Drug
Checkpoint Kinase Inhibitor AZD7762
CI-DRUG-00000151Explore in graph →NCIt C66961 CIViC
Regulatory
Approvals (0)
Each record names the authority, jurisdiction, indication text and status. A drug approved in one jurisdiction for one indication is not 'approved' in general.
Data not yet available
Derived
Development pipeline
Most advanced stage across all cancers, then per top-level cancer reached through trial conditions or approval indications. Approval in any ingested jurisdiction outranks trial phase; counts are interventional studies.
| Scope | Stage | Max phase | Active | Recruiting | Phase 3 | Trials | Approvals | Jurisdictions | First approval | First trial |
|---|---|---|---|---|---|---|---|---|---|---|
| All cancers | Phase1 | Phase 1 | 0 | 0 | 0 | 3 | 0 | — | — | 2006-12 |
- Source
- clinicaltrials
- Layer
- derived (computed by CancerIndex)
Data updated 19 hours agoSource updated unknown
Curated evidence
Clinical evidence (2)
CIViC items in which this therapy appears, grouped by cancer context, then molecular profile. 50 items per page.
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 29386107
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| RB1 Loss-of-function1 | ||||||||
| Checkpoint Kinase Inhibitor AZD7762 | ||||||||
Clinical trials
Trials with this intervention (3)
Most recently updated first, 50 per page.
- Source
- ClinicalTrials.gov
- Dataset
- ClinicalTrials.gov API v2 studies
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00473616 | Phase I Single Ascending Dose/Multiple Ascending Dose in Patients Treated With AZD7762 and Irinotecan | terminated | Phase 1 | 60 | AstraZenecaINDUSTRY | 1 | Feb 11, 2011 | clinicaltrials |
| NCT00937664 | Safety and Tolerability Study of AZD7762 in Combination With Gemcitabine | terminated | Phase 1 | 24 |