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Drugs
One entity per molecule (INN preferred); brand names and development codes are aliases. Approvals are always shown with jurisdiction and indication.
820 drugs
| Drug | Kind | Mechanism | Approvals | Evidence items | Trials | Identifiers |
|---|---|---|---|---|---|---|
| Uprosertib | Small Molecule | Serine/threonine-protein kinase AKT inhibitor | 0 | 4 | 11 | C84870 · CHEMBL3137336 |
| Vistusertib | Small Molecule | Serine/threonine-protein kinase mTOR inhibitor | 0 | 4 | 29 | C88329 · CHEMBL2336325 |
| AG1295 | Small Molecule | — | 0 | 3 | 0 | CHEMBL7724 |
| Alvespimycin | Small Molecule | Heat shock protein HSP90 inhibitor; Reactive oxygen species | 0 | 3 | 7 | C38142 · CHEMBL383824 |
| Anti-CTLA-4 Monoclonal Antibody | — | — | 0 | 3 | 0 | C128036 |
| Anti-VEGF Monoclonal Antibody | — | — | 0 | 3 | 1 | C2496 |
| ATR Inhibitor | — | — | 0 | 3 | 0 | C155926 |
| AZD-4547 | Small Molecule | — | 0 | 3 | 1 | CHEMBL3184679 |
| Birabresib | Small Molecule | Bromodomain and extra-terminal motif (BET) inhibitor | 0 | 3 | 5 | C103298 · CHEMBL3581647 |
| B-Raf/VEGFR-2 Inhibitor RAF265 | — | — | 0 | 3 | 1 | C61311 |
| Canertinib | Small Molecule | Epidermal growth factor receptor erbB1 inhibitor; Receptor protein-tyrosine kinase erbB-2 inhibitor; Receptor protein-tyrosine kinase erbB-4 inhibitor | 0 | 3 | 3 | C77588 · CHEMBL31965 |
| CDK4/6 Inhibition | — | — | 0 | 3 | 0 | C116938 |
| CDK Inhibitor SNS-032 | — | — | 0 | 3 | 0 | C62523 |
| Cisplatin/Pembrolizumab/Pemetrexed Regimen | — | — | 0 | 3 | 0 | C157397 |
| Deguelin | Small Molecule | — | 0 | 3 | 0 | C63666 · CHEMBL393417 |
| Dual IGF-1R/InsR Inhibitor BMS-754807 | — | — | 0 | 3 | 6 | C74043 |
| Durvalumab/Tremelimumab Regimen | — | — | 0 | 3 | 14 | C191202 |
| EAP Protocol | — | — | 0 | 3 | 0 | — |
| Everolimus/Exemestane Regimen | — | — | 0 | 3 | 1 | C142863 |
| FLT3/ABL/Aurora Kinase Inhibitor KW-2449 | — | — | 0 | 3 | 2 | C116858 |
| FOLFOX-4 Regimen | — | — | 0 | 3 | 13 | C63590 |
| IGF1R Monoclonal Antibody | — | — | 0 | 3 | 0 | — |
| Immunotherapy | — | — | 0 | 3 | 94 | C15262 |
| Ipatasertib | Small Molecule | Serine/threonine-protein kinase AKT inhibitor | 0 | 3 | 50 | C91072 · CHEMBL2177390 |
| KRAS G12D Inhibitor HRS-4642 | — | — | 0 | 3 | 7 | C192673 |
| KW2449 | — | — | 0 | 3 | 0 | — |
| Letetresgene Autoleucel | Gene Therapy | — | 0 | 3 | 7 | C121379 · CHEMBL4650238 |
| Mobocertinib | Small Molecule | Epidermal growth factor receptor erbB1 inhibitor | 0 | 3 | 2 | C126752 · CHEMBL4650319 |
| Nimotuzumab | Monoclonal Antibody | Epidermal growth factor receptor erbB1 inhibitor | 0 | 3 | 109 | C2733 · CHEMBL2108359 |
| PD98059 | — | — | 0 | 3 | 0 | — |
| Perifosine | Small Molecule | — | 0 | 3 | 41 | C1727 · CHEMBL372764 |
| R406 | — | — | 0 | 3 | 0 | — |
| RapaLink-1 | — | — | 0 | 3 | 0 | — |
| RDEA 119 | Small Molecule | Dual specificity mitogen-activated protein kinase kinase 1 inhibitor; Dual specificity mitogen-activated protein kinase kinase 2 inhibitor | 0 | 3 | 0 | CHEMBL1236682 |
| RG7112 | Small Molecule | — | 0 | 3 | 6 | CHEMBL2386346 |
| Ridaforolimus | Small Molecule | Serine/threonine-protein kinase mTOR inhibitor | 0 | 3 | 33 | C49061 · CHEMBL2103839 |
| Savolitinib | Small Molecule | Hepatocyte growth factor receptor inhibitor | 0 | 3 | 34 | C104732 · CHEMBL3334567 |
| SU5614 | — | — | 0 | 3 | 0 | — |
| Tandutinib | Small Molecule | Tyrosine-protein kinase receptor FLT3 inhibitor; Stem cell growth factor receptor inhibitor; Platelet-derived growth factor receptor beta inhibitor | 0 | 3 | 6 | C48404 · CHEMBL124660 |
| Tipifarnib | Small Molecule | Protein farnesyltransferase inhibitor | 0 | 3 | 79 | C1703 · CHEMBL289228 |
| Trichostatin A | — | — | 0 | 3 | 1 | C1261 |
| 5-Fluorouracil/Salicylic Acid Topical Solution | — | — | 0 | 2 | 0 | C97131 |
| 7-Ethyl-10-Hydroxycamptothecin | Small Molecule | DNA topoisomerase I inhibitor | 0 | 2 | 4 | C61618 · CHEMBL837 |
| Adjuvant Chemotherapy | — | — | 0 | 2 | 50 | C15360 |
| AGI-5198 | Small Molecule | — | 0 | 2 | 0 | CHEMBL2180727 |
| AGS324 | — | — | 0 | 2 | 0 | — |
| ALK2 Inhibitor LDN-193189 | — | — | 0 | 2 | 0 | — |
| Alvocidib | Small Molecule | Cyclin-dependent kinase 2 inhibitor; Cyclin-dependent kinase 4 inhibitor; Cyclin-dependent kinase 6 inhibitor; Cyclin-dependent kinase 9 inhibitor; Cyclin-dependent kinase 1 inhibitor; Cyclin-dependent kinase 7 inhibitor | 0 | 2 | 63 | C74940 · CHEMBL428690 |
| Amrubicin | Small Molecule | DNA topoisomerase II alpha inhibitor | 0 | 2 | 22 | C80089 · CHEMBL1186894 |
| Angiogenesis Inhibitor | — | — | 0 | 2 | 0 | C1742 |