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Drugs
One entity per molecule (INN preferred); brand names and development codes are aliases. Approvals are always shown with jurisdiction and indication.
820 drugs
| Drug | Kind | Mechanism | Approvals | Evidence items | Trials | Identifiers |
|---|---|---|---|---|---|---|
| RG7356 | — | — | 0 | 2 | 0 | — |
| Rigosertib | Small Molecule | — | 0 | 2 | 12 | C152216 · CHEMBL1241855 |
| Rovalpituzumab Tesirine | Adc | Delta-like protein 3 binding agent; DNA cross-linking agent | 0 | 2 | 14 | C107678 · CHEMBL3990011 |
| SAIT301 | — | — | 0 | 2 | 0 | — |
| Salinomycin | Small Molecule | — | 0 | 2 | 0 | C76430 · CHEMBL1208572 |
| Salirasib | Small Molecule | RAS inhibitor | 0 | 2 | 2 | C71146 · CHEMBL23293 |
| Selective Estrogen Receptor Covalent Antagonist H3B-6545 | — | — | 0 | 2 | 2 | C142980 |
| Selitrectinib | Small Molecule | Neurotrophic tyrosine kinase receptor inhibitor | 0 | 2 | 4 | C138160 · CHEMBL4297627 |
| Setidegrasib | Small Molecule | — | 0 | 2 | 3 | C206987 · CHEMBL6068173 |
| Sintilimab | Monoclonal Antibody | Programmed cell death protein 1 antagonist | 0 | 2 | 317 | C132992 · CHEMBL4297829 |
| Sotrastaurin Acetate | Small Molecule | Protein kinase C (PKC) inhibitor | 0 | 2 | 7 | C80631 · CHEMBL2105655 |
| Spliceostatin A | — | — | 0 | 2 | 0 | — |
| Tarextumab | Monoclonal Antibody | Neurogenic locus notch homolog protein 3 inhibitor; Neurogenic locus notch homolog protein 2 inhibitor | 0 | 2 | 3 | C95719 · CHEMBL3301588 |
| Therapeutic Tumor Infiltrating Lymphocytes | — | — | 0 | 2 | 50 | C28699 |
| Triciribine | Small Molecule | — | 0 | 2 | 4 | C142998 · CHEMBL331237 |
| Tyrosine Kinase Inhibitor | — | — | 0 | 2 | 14 | C1967 |
| Tyrphostin AG 1296 | — | — | 0 | 2 | 0 | C1731 |
| U0126 | — | — | 0 | 2 | 0 | — |
| Vatalanib | Small Molecule | Stem cell growth factor receptor inhibitor; Platelet-derived growth factor receptor inhibitor; Vascular endothelial growth factor receptor inhibitor; Macrophage colony stimulating factor receptor inhibitor | 0 | 2 | 25 | C1868 · CHEMBL101253 |
| Zenocutuzumab-zbco | Monoclonal Antibody | ErbB-2/ErbB-3 heterodimer inhibitor | 0 | 2 | 4 | CHEMBL4298025 |
| 2,4-pyrimidinediamine | — | — | 0 | 1 | 0 | — |
| 2-Deoxy-D-glucose | Small Molecule | — | 0 | 1 | 3 | C116618 · CHEMBL1880349 |
| 3-Dimensional Conformal Radiation Therapy | — | — | 0 | 1 | 0 | C16035 |
| 4'-(9-acridinylamino)methanesulfon-m-anisidide | — | — | 0 | 1 | 0 | — |
| 5-Fluoro-2-Deoxycytidine | — | — | 0 | 1 | 3 | C62785 |
| 6-(7-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl)-N-(4-(methylsulfonyl)phenyl)pyridin-2-amine | — | — | 0 | 1 | 0 | — |
| 9F7-F11 | — | — | 0 | 1 | 0 | — |
| A66 | — | — | 0 | 1 | 0 | — |
| Abemaciclib Regimen | — | — | 0 | 1 | 0 | C159980 |
| Abexinostat | Small Molecule | Histone deacetylase inhibitor | 0 | 1 | 14 | C68920 · CHEMBL2103863 |
| ACLY SiRNA | — | — | 0 | 1 | 0 | — |
| Adebrelimab | Monoclonal Antibody | Programmed cell death 1 ligand 1 inhibitor | 0 | 1 | 148 | C148535 · CHEMBL4297828 |
| Ado-trastuzumab Emtansine Regimen | — | — | 0 | 1 | 0 | C159982 |
| Afamitresgene Autoleucel | Gene Therapy | Melanoma-associated antigen 4 binding agent | 0 | 1 | 0 | C175738 · CHEMBL4802254 |
| Afimoxifene | Small Molecule | Estrogen receptor modulator; Estrogen-related receptor gamma antagonist | 0 | 1 | 5 | C975 · CHEMBL489 |
| Agerafenib | Small Molecule | Serine/threonine-protein kinase B-raf inhibitor; Epidermal growth factor receptor erbB1 inhibitor; Tyrosine-protein kinase receptor RET inhibitor | 0 | 1 | 3 | C107245 · CHEMBL2029988 |
| AKTi-1/2 | — | — | 0 | 1 | 0 | — |
| ALK/TRK Inhibitor TSR-011 | — | — | 0 | 1 | 1 | C114287 |
| AMG511 | — | — | 0 | 1 | 0 | — |
| Amuvatinib | Small Molecule | Tyrosine-protein kinase receptor FLT3 inhibitor; Stem cell growth factor receptor inhibitor; Hepatocyte growth factor receptor inhibitor; Platelet-derived growth factor receptor alpha inhibitor | 0 | 1 | 2 | C71750 · CHEMBL2103851 |
| Anthracycline Antineoplastic Antibiotic | — | — | 0 | 1 | 0 | C1594 |
| Anti-CD123 | — | — | 0 | 1 | 0 | — |
| Anti-EGFR Monoclonal Antibody | — | — | 0 | 1 | 5 | C133878 |
| Antiestrogen Therapy | — | — | 0 | 1 | 0 | C15757 |
| Antigen-specific Cytotoxic T-lymphocyte Therapy | — | — | 0 | 1 | 0 | — |
| Anti-HER3 Monoclonal Antibody GSK2849330 | — | — | 0 | 1 | 2 | C111997 |
| Anti-PDL1 Therapy | — | — | 0 | 1 | 0 | C217372 |
| Antisecretory Factor-enriched Egg Yolk Powder Supplement | — | — | 0 | 1 | 1 | C165649 |
| Anti-TIM-3 Monoclonal Antibody | — | — | 0 | 1 | 0 | C141146 |
| Anvumetostat | — | — | 0 | 1 | 5 | C185417 |