Country
United States
Cancer incidence and mortality for United States as published by the source registry: per site group, per year and sex, with age-standardized rates where the source provides them. Population statistics describe groups, never individuals.
- ISO 3166-1
- USA · US
- WHO region
- WHO Region of the Americas
- Population
- not seeded — CancerIndex shows only rates and counts published by the source
- Years covered
- 1999–2024
- Cancer entities
- 36
- Estimate types
- observed
Summary
2010 · Male · all ages
Totals across all cancer sites are shown only when the source publishes an all-sites row. Otherwise the per-site figures below stand on their own; CancerIndex never sums site groups (definitions overlap between sources).
- Deathshighest site group:Malignant Lung Neoplasm87,698countcdc-uscsProvenance
- Source
- U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality
- Dataset
- U.S. Cancer Statistics — Data Visualizations tool data tables (BYSITE.TXT)
- Version
- USCS 1999-2023 ASCII package, Nov 2025 submission (last-modified Thu, 04 Jun 2026 20:40:00 GMT; sha256 291765c997e5)
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- registry
- License
- US Government work (public domain); citation requested; statistical reporting and analysis only; no linkage for re-identification
- Run
- ING-CDCUSCS-20260908-000001
- New caseshighest site group:Malignant Prostate Neoplasm219,637countcdc-uscsProvenance
- Source
- U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality
- Dataset
- U.S. Cancer Statistics — Data Visualizations tool data tables (BYSITE.TXT)
- Version
- USCS 1999-2023 ASCII package, Nov 2025 submission (last-modified Thu, 04 Jun 2026 20:40:00 GMT; sha256 291765c997e5)
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- registry
- License
- US Government work (public domain); citation requested; statistical reporting and analysis only; no linkage for re-identification
- Run
- ING-CDCUSCS-20260908-000001
- Mortality rate (age-standardized)highest site group:Malignant Lung Neoplasm60.1per 100,000cdc-uscsProvenance
- Source
- U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality
- Dataset
- U.S. Cancer Statistics — Data Visualizations tool data tables (BYSITE.TXT)
- Version
- USCS 1999-2023 ASCII package, Nov 2025 submission (last-modified Thu, 04 Jun 2026 20:40:00 GMT; sha256 291765c997e5)
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- registry
- License
- US Government work (public domain); citation requested; statistical reporting and analysis only; no linkage for re-identification
- Run
- ING-CDCUSCS-20260908-000001
- Incidence rate (age-standardized)highest site group:Malignant Prostate Neoplasm137.7per 100,000cdc-uscsProvenance
- Source
- U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality
- Dataset
- U.S. Cancer Statistics — Data Visualizations tool data tables (BYSITE.TXT)
- Version
- USCS 1999-2023 ASCII package, Nov 2025 submission (last-modified Thu, 04 Jun 2026 20:40:00 GMT; sha256 291765c997e5)
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- registry
- License
- US Government work (public domain); citation requested; statistical reporting and analysis only; no linkage for re-identification
- Run
- ING-CDCUSCS-20260908-000001
No all-sites total in source for this scope — per-site figures below; no national total is computed.
Top cancers
By deaths
2010 · Male · all ages · 26 site groups
| # | Cancer | Deaths (count) | 95% CI | Type | Rank in scope | Site definition | Source |
|---|---|---|---|---|---|---|---|
| 1 | Malignant Lung NeoplasmCancer | 87,698 | — | observed | #1 of 26 | USCS "Lung and Bronchus" (ICD-10 C34; ICD-O-3 C340-C349) | cdc-uscsObserved |
| 2 | Malignant Prostate NeoplasmCancer | 28,560 | — | observed | #2 of 26 | USCS "Prostate" (ICD-10 C61; ICD-O-3 C619) | cdc-uscsObserved |
| 3 | Malignant Colon NeoplasmCancer | 21,494 | — | observed | #3 of 26 | USCS "Colon excluding Rectum" (ICD-10 C18, C26.0; ICD-O-3 C180-C189, C260) | cdc-uscsObserved |
| 4 | Malignant Pancreatic NeoplasmCancer | 18,699 | — | observed | #4 of 26 | USCS "Pancreas" (ICD-10 C25; ICD-O-3 C250-C259) | cdc-uscsObserved |
| 5 | Malignant Liver NeoplasmCancer | 13,657 | — | observed | #5 of 26 | USCS "Liver and Intrahepatic Bile Duct" (ICD-10 C22; ICD-O-3 C220-C221) | cdc-uscsObserved |
| 6 | LeukemiaCancer Family | 12,912 | — | observed | #6 of 26 | USCS "Leukemias" (ICD-10 C91-C95 (leukemia recodes; C90.1 plasma cell leukemia included by SEER); ICD-O-3 leukemia histologies 9733-9948 per SEER site recode) | cdc-uscsObserved |
| 7 | Malignant Esophageal NeoplasmCancer | 11,416 | — | observed | #7 of 26 | USCS "Esophagus" (ICD-10 C15; ICD-O-3 C150-C159) | cdc-uscsObserved |
| 8 | Non-Hodgkin LymphomaHematologic Malignancy | 11,047 | — | observed | #8 of 26 | USCS "Non-Hodgkin Lymphoma" (ICD-10 C82-C85, C96.3; ICD-O-3 histology 9590-9597, 9670-9729, 9735, 9737-9738 (+9811-9818, 9823, 9827, 9837 outside marrow/blood)) | cdc-uscsObserved |
| 9 | Malignant Bladder NeoplasmCancer | 10,428 | — | observed | #9 of 26 | USCS "Urinary Bladder" (ICD-10 C67; ICD-O-3 C670-C679) | cdc-uscsObserved |
| 10 | Malignant Kidney NeoplasmCancer | 8,436 | — | observed | #10 of 26 | USCS "Kidney and Renal Pelvis" (ICD-10 C64-C65; ICD-O-3 C649, C659) | cdc-uscsObserved |
| 11 | Malignant Central Nervous System NeoplasmCancer | 7,977 | — | observed | #11 of 26 | USCS "Brain and Other Nervous System" (ICD-10 C70, C71, C72; ICD-O-3 C700-C709, C710-C719, C720-C729) | cdc-uscsObserved |
| 12 | Malignant Gastric NeoplasmCancer | 6,703 | — | observed | #12 of 26 | USCS "Stomach" (ICD-10 C16; ICD-O-3 C160-C169) | cdc-uscsObserved |
| 13 | Cutaneous MelanomaCancer | 6,002 | — | observed | #13 of 26 | USCS "Melanomas of the Skin" (ICD-10 C43; ICD-O-3 C440-C449 with histology 8720-8790) | cdc-uscsObserved |
| 14 | Multiple MyelomaHematologic Malignancy | 5,881 | — | observed | #14 of 26 | USCS "Myeloma" (ICD-10 C90.0, C90.2; ICD-O-3 histology 9731-9732, 9734) | cdc-uscsObserved |
| 15 | Malignant Rectal NeoplasmCancer | 5,579 | — | observed | #15 of 26 | USCS "Rectum and Rectosigmoid Junction" (ICD-10 C19-C20; ICD-O-3 C199, C209) | cdc-uscsObserved |
| 16 | Malignant Laryngeal NeoplasmCancer | 2,951 | — | observed | #16 of 26 | USCS "Larynx" (ICD-10 C32; ICD-O-3 C320-C329) | cdc-uscsObserved |
| 17 | Malignant MesotheliomaCancer Family | 2,044 | — | observed | #17 of 26 | USCS "Mesothelioma" (ICD-10 C45; ICD-O-3 histology 9050-9055 (any site)) | cdc-uscsObserved |
| 18 | Malignant Thyroid Gland NeoplasmCancer | 723 | — | observed | #18 of 26 | USCS "Thyroid" (ICD-10 C73; ICD-O-3 C739) | cdc-uscsObserved |
| 19 | Hodgkin LymphomaHematologic Malignancy | 714 | — | observed | #19 of 26 | USCS "Hodgkin Lymphoma" (ICD-10 C81; ICD-O-3 histology 9650-9667 (nodal and extranodal)) | cdc-uscsObserved |
| 20 | Malignant Salivary Gland NeoplasmCancer | 541 | — | observed | #20 of 26 | USCS "Salivary Gland" (ICD-10 C07-C08; ICD-O-3 C079-C089) | cdc-uscsObserved |
| 21 | Malignant Nasopharyngeal NeoplasmCancer | 479 | — | observed | #21 of 26 | USCS "Nasopharynx" (ICD-10 C11; ICD-O-3 C110-C119) | cdc-uscsObserved |
| 22 | Malignant Breast NeoplasmCancer Family | 439 | — | observed | #22 of 26 | USCS "Male Breast" (ICD-10 C50; ICD-O-3 C500-C509) | cdc-uscsObserved |
| 23 | Malignant Testicular NeoplasmCancer | 399 | — | observed | #23 of 26 | USCS "Testis" (ICD-10 C62; ICD-O-3 C620-C629) | cdc-uscsObserved |
| 24 | Malignant Anal NeoplasmCancer | 335 | — | observed | #24 of 26 | USCS "Anus, Anal Canal and Anorectum" (ICD-10 C21; ICD-O-3 C210-C212, C218) | cdc-uscsObserved |
| 25 | Malignant Penile NeoplasmCancer | 258 | — | observed | #25 of 26 | USCS "Penis" (ICD-10 C60; ICD-O-3 C600-C609) | cdc-uscsObserved |
| 26 | Malignant Hypopharyngeal NeoplasmCancer | 253 | — | observed | #26 of 26 | USCS "Hypopharynx" (ICD-10 C12-C13; ICD-O-3 C129, C130-C139) | cdc-uscsObserved |
- Source
- U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality
- Dataset
- U.S. Cancer Statistics — Data Visualizations tool data tables (BYSITE.TXT)
- Version
- USCS 1999-2023 ASCII package, Nov 2025 submission (last-modified Thu, 04 Jun 2026 20:40:00 GMT; sha256 291765c997e5)
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- registry
- License
- US Government work (public domain); citation requested; statistical reporting and analysis only; no linkage for re-identification
- Run
- ING-CDCUSCS-20260908-000001
Data updated 22 days agoSource updated USCS 1999-2023 ASCII package, Nov 2025 submission (last-modified Thu, 04 Jun 2026 20:40:00 GMT; sha256 291765c997e5)
Top cancers
By new cases
2010 · Male · all ages · 27 site groups
| # | Cancer | New cases (count) | 95% CI | Type | Rank in scope | Site definition | Source |
|---|---|---|---|---|---|---|---|
| 1 | Malignant Prostate NeoplasmCancer | 219,637 | — | observed | #1 of 27 | USCS "Prostate" (ICD-10 C61; ICD-O-3 C619) | cdc-uscsObserved |
| 2 | Malignant Lung NeoplasmCancer | 114,900 | — | observed | #2 of 27 | USCS "Lung and Bronchus" (ICD-10 C34; ICD-O-3 C340-C349) | cdc-uscsObserved |
| 3 | Malignant Bladder NeoplasmCancer | 53,679 | — | observed | #3 of 27 | USCS "Urinary Bladder" (ICD-10 C67; ICD-O-3 C670-C679) | cdc-uscsObserved |
| 4 | Malignant Colon NeoplasmCancer | 49,661 | — | observed | #4 of 27 | USCS "Colon excluding Rectum" (ICD-10 C18, C26.0; ICD-O-3 C180-C189, C260) | cdc-uscsObserved |
| 5 | Cutaneous MelanomaCancer | 38,815 | — | observed | #5 of 27 | USCS "Melanomas of the Skin" (ICD-10 C43; ICD-O-3 C440-C449 with histology 8720-8790) | cdc-uscsObserved |
| 6 | Non-Hodgkin LymphomaHematologic Malignancy | 35,656 | — | observed | #6 of 27 | USCS "Non-Hodgkin Lymphoma" (ICD-10 C82-C85, C96.3; ICD-O-3 histology 9590-9597, 9670-9729, 9735, 9737-9738 (+9811-9818, 9823, 9827, 9837 outside marrow/blood)) | cdc-uscsObserved |
| 7 | Malignant Kidney NeoplasmCancer | 33,939 | — | observed | #7 of 27 | USCS "Kidney and Renal Pelvis" (ICD-10 C64-C65; ICD-O-3 C649, C659) | cdc-uscsObserved |
| 8 | LeukemiaCancer Family | 27,951 | — | observed | #8 of 27 | USCS "Leukemias" (ICD-10 C91-C95 (leukemia recodes; C90.1 plasma cell leukemia included by SEER); ICD-O-3 leukemia histologies 9733-9948 per SEER site recode) | cdc-uscsObserved |
| 9 | Malignant Rectal NeoplasmCancer | 23,016 | — | observed | #9 of 27 | USCS "Rectum and Rectosigmoid Junction" (ICD-10 C19-C20; ICD-O-3 C199, C209) | cdc-uscsObserved |
| 10 | Malignant Pancreatic NeoplasmCancer | 20,983 | — | observed | #10 of 27 | USCS "Pancreas" (ICD-10 C25; ICD-O-3 C250-C259) | cdc-uscsObserved |
| 11 | Malignant Liver NeoplasmCancer | 18,742 | — | observed | #11 of 27 | USCS "Liver and Intrahepatic Bile Duct" (ICD-10 C22; ICD-O-3 C220-C221) | cdc-uscsObserved |
| 12 | Malignant Gastric NeoplasmCancer | 14,076 | — | observed | #12 of 27 | USCS "Stomach" (ICD-10 C16; ICD-O-3 C160-C169) | cdc-uscsObserved |
| 13 | Malignant Esophageal NeoplasmCancer | 12,592 | — | observed | #13 of 27 | USCS "Esophagus" (ICD-10 C15; ICD-O-3 C150-C159) | cdc-uscsObserved |
| 14 | Multiple MyelomaHematologic Malignancy | 12,352 | — | observed | #14 of 27 | USCS "Myeloma" (ICD-10 C90.0, C90.2; ICD-O-3 histology 9731-9732, 9734) | cdc-uscsObserved |
| 15 | Malignant Central Nervous System NeoplasmCancer | 12,127 | — | observed | #15 of 27 | USCS "Brain and Other Nervous System" (ICD-10 C70, C71, C72; ICD-O-3 C700-C709, C710-C719, C720-C729) | cdc-uscsObserved |
| 16 | Malignant Thyroid Gland NeoplasmCancer | 10,848 | — | observed | #16 of 27 | USCS "Thyroid" (ICD-10 C73; ICD-O-3 C739) | cdc-uscsObserved |
| 17 | Malignant Laryngeal NeoplasmCancer | 10,296 | — | observed | #17 of 27 | USCS "Larynx" (ICD-10 C32; ICD-O-3 C320-C329) | cdc-uscsObserved |
| 18 | Malignant Testicular NeoplasmCancer | 8,353 | — | observed | #18 of 27 | USCS "Testis" (ICD-10 C62; ICD-O-3 C620-C629) | cdc-uscsObserved |
| 19 | Hodgkin LymphomaHematologic Malignancy | 4,885 | — | observed | #19 of 27 | USCS "Hodgkin Lymphoma" (ICD-10 C81; ICD-O-3 histology 9650-9667 (nodal and extranodal)) | cdc-uscsObserved |
| 20 | Malignant MesotheliomaCancer Family | 2,569 | — | observed | #20 of 27 | USCS "Mesothelioma" (ICD-10 C45; ICD-O-3 histology 9050-9055 (any site)) | cdc-uscsObserved |
| 21 | Malignant Salivary Gland NeoplasmCancer | 2,478 | — | observed | #21 of 27 | USCS "Salivary Gland" (ICD-10 C07-C08; ICD-O-3 C079-C089) | cdc-uscsObserved |
| 22 | Malignant Anal NeoplasmCancer | 2,270 | — | observed | #22 of 27 | USCS "Anus, Anal Canal and Anorectum" (ICD-10 C21; ICD-O-3 C210-C212, C218) | cdc-uscsObserved |
| 23 | Malignant Breast NeoplasmCancer Family | 1,938 | — | observed | #23 of 27 | USCS "Male Breast" (ICD-10 C50; ICD-O-3 C500-C509) | cdc-uscsObserved |
| 24 | Malignant Hypopharyngeal NeoplasmCancer | 1,864 | — | observed | #24 of 27 | USCS "Hypopharynx" (ICD-10 C12-C13; ICD-O-3 C129, C130-C139) | cdc-uscsObserved |
| 25 | Malignant Nasopharyngeal NeoplasmCancer | 1,308 | — | observed | #25 of 27 | USCS "Nasopharynx" (ICD-10 C11; ICD-O-3 C110-C119) | cdc-uscsObserved |
| 26 | Malignant Penile NeoplasmCancer | 1,269 | — | observed | #26 of 27 | USCS "Penis" (ICD-10 C60; ICD-O-3 C600-C609) | cdc-uscsObserved |
| 27 | Kaposi SarcomaCancer | 1,067 | — | observed | #27 of 27 | USCS "Kaposi Sarcoma" (ICD-10 C46; ICD-O-3 histology 9140 (any site)) | cdc-uscsObserved |
- Source
- U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality
- Dataset
- U.S. Cancer Statistics — Data Visualizations tool data tables (BYSITE.TXT)
- Version
- USCS 1999-2023 ASCII package, Nov 2025 submission (last-modified Thu, 04 Jun 2026 20:40:00 GMT; sha256 291765c997e5)
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- registry
- License
- US Government work (public domain); citation requested; statistical reporting and analysis only; no linkage for re-identification
- Run
- ING-CDCUSCS-20260908-000001
Data updated 22 days agoSource updated USCS 1999-2023 ASCII package, Nov 2025 submission (last-modified Thu, 04 Jun 2026 20:40:00 GMT; sha256 291765c997e5)
Top cancers
By mortality rate (age-standardized)
2010 · Male · all ages · 26 site groups · 2000 U.S. standard population (19 age groups)
| # | Cancer | Mortality rate (age-standardized) (per 100,000) | 95% CI | Type | Rank in scope | Site definition | Source |
|---|---|---|---|---|---|---|---|
| 1 | Malignant Lung NeoplasmCancer | 60.1 | 59.7–60.5 | observed | #1 of 26 | USCS "Lung and Bronchus" (ICD-10 C34; ICD-O-3 C340-C349) | cdc-uscsObserved |
| 2 | Malignant Prostate NeoplasmCancer | 21.8 | 21.6–22.1 | observed | #2 of 26 | USCS "Prostate" (ICD-10 C61; ICD-O-3 C619) | cdc-uscsObserved |
| 3 | Malignant Colon NeoplasmCancer | 15 | 14.8–15.2 | observed | #3 of 26 | USCS "Colon excluding Rectum" (ICD-10 C18, C26.0; ICD-O-3 C180-C189, C260) | cdc-uscsObserved |
| 4 | Malignant Pancreatic NeoplasmCancer | 12.7 | 12.5–12.9 | observed | #4 of 26 | USCS "Pancreas" (ICD-10 C25; ICD-O-3 C250-C259) | cdc-uscsObserved |
| 5 | LeukemiaCancer Family | 9.3 | 9.1–9.4 | observed | #5 of 26 | USCS "Leukemias" (ICD-10 C91-C95 (leukemia recodes; C90.1 plasma cell leukemia included by SEER); ICD-O-3 leukemia histologies 9733-9948 per SEER site recode) | cdc-uscsObserved |
| 6 | Malignant Liver NeoplasmCancer | 8.7 | 8.6–8.9 | observed | #6 of 26 | USCS "Liver and Intrahepatic Bile Duct" (ICD-10 C22; ICD-O-3 C220-C221) | cdc-uscsObserved |
| 7 | Non-Hodgkin LymphomaHematologic Malignancy | 7.8 | 7.7–8 | observed | #7 of 26 | USCS "Non-Hodgkin Lymphoma" (ICD-10 C82-C85, C96.3; ICD-O-3 histology 9590-9597, 9670-9729, 9735, 9737-9738 (+9811-9818, 9823, 9827, 9837 outside marrow/blood)) | cdc-uscsObserved |
| 8 | Malignant Bladder NeoplasmCancer | 7.7 | 7.6–7.9 | observed | #8 of 26 | USCS "Urinary Bladder" (ICD-10 C67; ICD-O-3 C670-C679) | cdc-uscsObserved |
| 9 | Malignant Esophageal NeoplasmCancer | 7.5 | 7.4–7.7 | observed | #9 of 26 | USCS "Esophagus" (ICD-10 C15; ICD-O-3 C150-C159) | cdc-uscsObserved |
| 10 | Malignant Kidney NeoplasmCancer | 5.7 | 5.6–5.8 | observed | #10 of 26 | USCS "Kidney and Renal Pelvis" (ICD-10 C64-C65; ICD-O-3 C649, C659) | cdc-uscsObserved |
| 11 | Malignant Central Nervous System NeoplasmCancer | 5.2 | 5.1–5.3 | observed | #11 of 26 | USCS "Brain and Other Nervous System" (ICD-10 C70, C71, C72; ICD-O-3 C700-C709, C710-C719, C720-C729) | cdc-uscsObserved |
| 12 | Malignant Gastric NeoplasmCancer | 4.6 | 4.5–4.8 | observed | #12 of 26 | USCS "Stomach" (ICD-10 C16; ICD-O-3 C160-C169) | cdc-uscsObserved |
| 13 | Multiple MyelomaHematologic Malignancy | 4.2 | 4.1–4.3 | observed | #13 of 26 | USCS "Myeloma" (ICD-10 C90.0, C90.2; ICD-O-3 histology 9731-9732, 9734) | cdc-uscsObserved |
| 14 | Cutaneous MelanomaCancer | 4.1 | 4–4.2 | observed | #14 of 26 | USCS "Melanomas of the Skin" (ICD-10 C43; ICD-O-3 C440-C449 with histology 8720-8790) | cdc-uscsObserved |
| 15 | Malignant Rectal NeoplasmCancer | 3.7 | 3.6–3.8 | observed | #15 of 26 | USCS "Rectum and Rectosigmoid Junction" (ICD-10 C19-C20; ICD-O-3 C199, C209) | cdc-uscsObserved |
| 16 | Malignant Laryngeal NeoplasmCancer | 1.9 | 1.9–2 | observed | #16 of 26 | USCS "Larynx" (ICD-10 C32; ICD-O-3 C320-C329) | cdc-uscsObserved |
| 17 | Malignant MesotheliomaCancer Family | 1.5 | 1.4–1.6 | observed | #17 of 26 | USCS "Mesothelioma" (ICD-10 C45; ICD-O-3 histology 9050-9055 (any site)) | cdc-uscsObserved |
| 18 | Hodgkin LymphomaHematologic Malignancy | 0.5 | 0.5–0.5 | observed | #18 of 26 | USCS "Hodgkin Lymphoma" (ICD-10 C81; ICD-O-3 histology 9650-9667 (nodal and extranodal)) | cdc-uscsObserved |
| 19 | Malignant Thyroid Gland NeoplasmCancer | 0.5 | 0.5–0.5 | observed | #18 of 26 | USCS "Thyroid" (ICD-10 C73; ICD-O-3 C739) | cdc-uscsObserved |
| 20 | Malignant Salivary Gland NeoplasmCancer | 0.4 | 0.3–0.4 | observed | #20 of 26 | USCS "Salivary Gland" (ICD-10 C07-C08; ICD-O-3 C079-C089) | cdc-uscsObserved |
| 21 | Malignant Breast NeoplasmCancer Family | 0.3 | 0.3–0.3 | observed | #21 of 26 | USCS "Male Breast" (ICD-10 C50; ICD-O-3 C500-C509) | cdc-uscsObserved |
| 22 | Malignant Nasopharyngeal NeoplasmCancer | 0.3 | 0.3–0.3 | observed | #21 of 26 | USCS "Nasopharynx" (ICD-10 C11; ICD-O-3 C110-C119) | cdc-uscsObserved |
| 23 | Malignant Testicular NeoplasmCancer | 0.3 | 0.2–0.3 | observed | #21 of 26 | USCS "Testis" (ICD-10 C62; ICD-O-3 C620-C629) | cdc-uscsObserved |
| 24 | Malignant Anal NeoplasmCancer | 0.2 | 0.2–0.2 | observed | #24 of 26 | USCS "Anus, Anal Canal and Anorectum" (ICD-10 C21; ICD-O-3 C210-C212, C218) | cdc-uscsObserved |
| 25 | Malignant Hypopharyngeal NeoplasmCancer | 0.2 | 0.1–0.2 | observed | #24 of 26 | USCS "Hypopharynx" (ICD-10 C12-C13; ICD-O-3 C129, C130-C139) | cdc-uscsObserved |
| 26 | Malignant Penile NeoplasmCancer | 0.2 | 0.2–0.2 | observed | #24 of 26 | USCS "Penis" (ICD-10 C60; ICD-O-3 C600-C609) | cdc-uscsObserved |
- Source
- U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality
- Dataset
- U.S. Cancer Statistics — Data Visualizations tool data tables (BYSITE.TXT)
- Version
- USCS 1999-2023 ASCII package, Nov 2025 submission (last-modified Thu, 04 Jun 2026 20:40:00 GMT; sha256 291765c997e5)
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- registry
- License
- US Government work (public domain); citation requested; statistical reporting and analysis only; no linkage for re-identification
- Run
- ING-CDCUSCS-20260908-000001
Data updated 22 days agoSource updated USCS 1999-2023 ASCII package, Nov 2025 submission (last-modified Thu, 04 Jun 2026 20:40:00 GMT; sha256 291765c997e5)
Top cancers
By incidence rate (age-standardized)
2010 · Male · all ages · 27 site groups · 2000 U.S. standard population (19 age groups)
| # | Cancer | Incidence rate (age-standardized) (per 100,000) | 95% CI | Type | Rank in scope | Site definition | Source |
|---|---|---|---|---|---|---|---|
| 1 | Malignant Prostate NeoplasmCancer | 137.7 | 137.1–138.3 | observed | #1 of 27 | USCS "Prostate" (ICD-10 C61; ICD-O-3 C619) | cdc-uscsObserved |
| 2 | Malignant Lung NeoplasmCancer | 77.3 | 76.8–77.8 | observed | #2 of 27 | USCS "Lung and Bronchus" (ICD-10 C34; ICD-O-3 C340-C349) | cdc-uscsObserved |
| 3 | Malignant Bladder NeoplasmCancer | 37.3 | 37–37.7 | observed | #3 of 27 | USCS "Urinary Bladder" (ICD-10 C67; ICD-O-3 C670-C679) | cdc-uscsObserved |
| 4 | Malignant Colon NeoplasmCancer | 33.6 | 33.3–33.9 | observed | #4 of 27 | USCS "Colon excluding Rectum" (ICD-10 C18, C26.0; ICD-O-3 C180-C189, C260) | cdc-uscsObserved |
| 5 | Cutaneous MelanomaCancer | 25.8 | 25.5–26.1 | observed | #5 of 27 | USCS "Melanomas of the Skin" (ICD-10 C43; ICD-O-3 C440-C449 with histology 8720-8790) | cdc-uscsObserved |
| 6 | Non-Hodgkin LymphomaHematologic Malignancy | 23.9 | 23.6–24.1 | observed | #6 of 27 | USCS "Non-Hodgkin Lymphoma" (ICD-10 C82-C85, C96.3; ICD-O-3 histology 9590-9597, 9670-9729, 9735, 9737-9738 (+9811-9818, 9823, 9827, 9837 outside marrow/blood)) | cdc-uscsObserved |
| 7 | Malignant Kidney NeoplasmCancer | 21.8 | 21.6–22.1 | observed | #7 of 27 | USCS "Kidney and Renal Pelvis" (ICD-10 C64-C65; ICD-O-3 C649, C659) | cdc-uscsObserved |
| 8 | LeukemiaCancer Family | 19 | 18.7–19.2 | observed | #8 of 27 | USCS "Leukemias" (ICD-10 C91-C95 (leukemia recodes; C90.1 plasma cell leukemia included by SEER); ICD-O-3 leukemia histologies 9733-9948 per SEER site recode) | cdc-uscsObserved |
| 9 | Malignant Rectal NeoplasmCancer | 14.8 | 14.6–15 | observed | #9 of 27 | USCS "Rectum and Rectosigmoid Junction" (ICD-10 C19-C20; ICD-O-3 C199, C209) | cdc-uscsObserved |
| 10 | Malignant Pancreatic NeoplasmCancer | 14 | 13.8–14.2 | observed | #10 of 27 | USCS "Pancreas" (ICD-10 C25; ICD-O-3 C250-C259) | cdc-uscsObserved |
| 11 | Malignant Liver NeoplasmCancer | 11.5 | 11.3–11.7 | observed | #11 of 27 | USCS "Liver and Intrahepatic Bile Duct" (ICD-10 C22; ICD-O-3 C220-C221) | cdc-uscsObserved |
| 12 | Malignant Gastric NeoplasmCancer | 9.5 | 9.3–9.6 | observed | #12 of 27 | USCS "Stomach" (ICD-10 C16; ICD-O-3 C160-C169) | cdc-uscsObserved |
| 13 | Multiple MyelomaHematologic Malignancy | 8.3 | 8.1–8.4 | observed | #13 of 27 | USCS "Myeloma" (ICD-10 C90.0, C90.2; ICD-O-3 histology 9731-9732, 9734) | cdc-uscsObserved |
| 14 | Malignant Esophageal NeoplasmCancer | 8.1 | 8–8.3 | observed | #14 of 27 | USCS "Esophagus" (ICD-10 C15; ICD-O-3 C150-C159) | cdc-uscsObserved |
| 15 | Malignant Central Nervous System NeoplasmCancer | 7.9 | 7.8–8.1 | observed | #15 of 27 | USCS "Brain and Other Nervous System" (ICD-10 C70, C71, C72; ICD-O-3 C700-C709, C710-C719, C720-C729) | cdc-uscsObserved |
| 16 | Malignant Thyroid Gland NeoplasmCancer | 7 | 6.8–7.1 | observed | #16 of 27 | USCS "Thyroid" (ICD-10 C73; ICD-O-3 C739) | cdc-uscsObserved |
| 17 | Malignant Laryngeal NeoplasmCancer | 6.5 | 6.4–6.6 | observed | #17 of 27 | USCS "Larynx" (ICD-10 C32; ICD-O-3 C320-C329) | cdc-uscsObserved |
| 18 | Malignant Testicular NeoplasmCancer | 5.6 | 5.5–5.7 | observed | #18 of 27 | USCS "Testis" (ICD-10 C62; ICD-O-3 C620-C629) | cdc-uscsObserved |
| 19 | Hodgkin LymphomaHematologic Malignancy | 3.2 | 3.1–3.3 | observed | #19 of 27 | USCS "Hodgkin Lymphoma" (ICD-10 C81; ICD-O-3 histology 9650-9667 (nodal and extranodal)) | cdc-uscsObserved |
| 20 | Malignant MesotheliomaCancer Family | 1.9 | 1.8–1.9 | observed | #20 of 27 | USCS "Mesothelioma" (ICD-10 C45; ICD-O-3 histology 9050-9055 (any site)) | cdc-uscsObserved |
| 21 | Malignant Salivary Gland NeoplasmCancer | 1.7 | 1.6–1.8 | observed | #21 of 27 | USCS "Salivary Gland" (ICD-10 C07-C08; ICD-O-3 C079-C089) | cdc-uscsObserved |
| 22 | Malignant Anal NeoplasmCancer | 1.5 | 1.4–1.5 | observed | #22 of 27 | USCS "Anus, Anal Canal and Anorectum" (ICD-10 C21; ICD-O-3 C210-C212, C218) | cdc-uscsObserved |
| 23 | Malignant Breast NeoplasmCancer Family | 1.3 | 1.2–1.4 | observed | #23 of 27 | USCS "Male Breast" (ICD-10 C50; ICD-O-3 C500-C509) | cdc-uscsObserved |
| 24 | Malignant Hypopharyngeal NeoplasmCancer | 1.2 | 1.1–1.2 | observed | #24 of 27 | USCS "Hypopharynx" (ICD-10 C12-C13; ICD-O-3 C129, C130-C139) | cdc-uscsObserved |
| 25 | Malignant Penile NeoplasmCancer | 0.9 | 0.8–0.9 | observed | #25 of 27 | USCS "Penis" (ICD-10 C60; ICD-O-3 C600-C609) | cdc-uscsObserved |
| 26 | Malignant Nasopharyngeal NeoplasmCancer | 0.8 | 0.8–0.9 | observed | #26 of 27 | USCS "Nasopharynx" (ICD-10 C11; ICD-O-3 C110-C119) | cdc-uscsObserved |
| 27 | Kaposi SarcomaCancer | 0.7 | 0.7–0.8 | observed | #27 of 27 | USCS "Kaposi Sarcoma" (ICD-10 C46; ICD-O-3 histology 9140 (any site)) | cdc-uscsObserved |
- Source
- U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality
- Dataset
- U.S. Cancer Statistics — Data Visualizations tool data tables (BYSITE.TXT)
- Version
- USCS 1999-2023 ASCII package, Nov 2025 submission (last-modified Thu, 04 Jun 2026 20:40:00 GMT; sha256 291765c997e5)
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- registry
- License
- US Government work (public domain); citation requested; statistical reporting and analysis only; no linkage for re-identification
- Run
- ING-CDCUSCS-20260908-000001
Data updated 22 days agoSource updated USCS 1999-2023 ASCII package, Nov 2025 submission (last-modified Thu, 04 Jun 2026 20:40:00 GMT; sha256 291765c997e5)
Trend
Mortality rate (age-standardized) — top 8 cancers, all years
Top cancers of 2010 (Male) traced over every year published for United States. Dashed lines mark estimated or projected values; the y axis starts at zero.
cdc-uscsObservedstandard: 2000 U.S. standard population (19 age groups)264 points
Clinical research
Clinical trial activity in United States
Registrant-entered study locations on ClinicalTrials.gov mapped to this country (any study type, any phase). A site is one location; a multi-site study weighs by its number of sites. Recruiting = location status RECRUITING, or the study status when the site has none.
- Sites
- 609,751
- Studies with a site here
- 50,884
- Recruiting sites
- 71,552
- Recruiting studies
- 7,740
Computed formula ci-trial-sites-v1 · source: clinicaltrials · shares are of sites, not of studies
Data updated 16 hours agoSource updated unknowntrial_site_country_counts
Regulatory
Oncology approval records · US
Records of the country's regulator as ingested (one record = one decision for one application or product identifier). Absence of a record here is not evidence of absence.
FDA · approved: 2,343 records / 304 drugs
- Sep 18, 2026Abemaciclib approved cancer not stated in this recordEfficacy supplement 2026-09-18 (see label)openfda
- Sep 9, 2026Aminolevulinic Acid approved cancer not stated in this recordEfficacy supplement 2026-09-09 (see label)openfda
- Sep 9, 2026Sevabertinib approved cancer not stated in this recordEfficacy supplement 2026-09-09 (see label)openfda
- Sep 4, 2026Camizestrant approved Malignant Breast Neoplasmin combination with a CDK4/6 inhibitor (abemaciclib, palbociclib, or ribociclib) for the treatment of adult patients with hormone receptor…openfda
- Aug 28, 2026Ropeginterferon Alfa-2b approved cancer not stated in this recordEfficacy supplement 2026-08-28 (see label)openfda
- Aug 25, 2026Zanidatamab approved cancer not stated in this recordEfficacy supplement 2026-08-25 (see label)openfda
- Aug 25, 2026Tislelizumab approved cancer not stated in this recordEfficacy supplement 2026-08-25 (see label)openfda
- Jul 24, 2026Enzalutamide approved cancer not stated in this recordEfficacy supplement 2026-07-24 (see label)openfda
- Jul 24, 2026Enzalutamide approved cancer not stated in this recordEfficacy supplement 2026-07-24 (see label)openfda
- Jul 14, 2026Selpercatinib approved cancer not stated in this recordEfficacy supplement 2026-07-14 (see label)openfda
Regulatory
Provenance
Sources and freshness
What each source covers for this geography, exactly as ingested. Values are normalized (units, labels) but never changed.
| Source | Metric | Sex | Years | Cancers | Estimate types | Standard population | Ingested |
|---|---|---|---|---|---|---|---|
| cdc-uscs | Incidence rate (age-standardized) | Both | 1999–2023 (25) | 24 | observed | 2000 U.S. standard population (19 age groups) | 2026-09-08 |
| cdc-uscs | Incidence rate (age-standardized) | Female | 1999–2023 (25) | 29 | observed | 2000 U.S. standard population (19 age groups) | 2026-09-08 |
| cdc-uscs | Incidence rate (age-standardized) | Male | 1999–2023 (25) | 27 | observed | 2000 U.S. standard population (19 age groups) | 2026-09-08 |
| cdc-uscs | Mortality rate (age-standardized) | Both | 1999–2024 (26) | 23 | observed | 2000 U.S. standard population (19 age groups) | 2026-09-08 |
| cdc-wonder | Mortality rate (age-standardized) | Both | 2018–2024 (7) | 36 | observed | 2000 U.S. Std. Population | 2026-09-08 |
| cdc-uscs | Mortality rate (age-standardized) | Female | 1999–2024 (26) | 28 | observed | 2000 U.S. standard population (19 age groups) | 2026-09-08 |
| cdc-wonder | Mortality rate (age-standardized) | Female | 2018–2024 (7) | 36 | observed | 2000 U.S. Std. Population | 2026-09-08 |
| cdc-uscs | Mortality rate (age-standardized) | Male | 1999–2024 (26) | 26 | observed | 2000 U.S. standard population (19 age groups) | 2026-09-08 |
| cdc-wonder | Mortality rate (age-standardized) | Male | 2018–2024 (7) | 36 | observed | 2000 U.S. Std. Population | 2026-09-08 |
| cdc-uscs | New cases | Both | 1999–2023 (25) | 32 | observed | — | 2026-09-08 |
| cdc-uscs | New cases | Female | 1999–2023 (25) | 29 | observed | — | 2026-09-08 |
| cdc-uscs | New cases | Male | 1999–2023 (25) | 27 | observed | — | 2026-09-08 |
| cdc-uscs | Deaths | Both | 1999–2024 (26) | 31 | observed | — | 2026-09-08 |
| cdc-wonder | Deaths | Both | 2018–2024 (7) | 36 | observed | — | 2026-09-08 |
| cdc-uscs | Deaths | Female | 1999–2024 (26) | 28 | observed | — | 2026-09-08 |
| cdc-wonder | Deaths | Female | 2018–2024 (7) | 36 | observed | — | 2026-09-08 |
| cdc-uscs | Deaths | Male | 1999–2024 (26) | 26 | observed | — | 2026-09-08 |
| cdc-wonder | Deaths | Male | 2018–2024 (7) | 36 | observed | — | 2026-09-08 |
| cdc-wonder | Mortality rate (crude) | Both | 2018–2024 (7) | 36 | observed | — | 2026-09-08 |
| cdc-wonder | Mortality rate (crude) | Female | 2018–2024 (7) | 36 | observed | — | 2026-09-08 |
| cdc-wonder | Mortality rate (crude) | Male | 2018–2024 (7) | 36 | observed | — | 2026-09-08 |
- U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortalitylicense: approvedUS Government work (public domain); citation requested; statistical reporting and analysis only; no linkage for re-identification
- CDC WONDER — Underlying Cause of Death (US mortality by ICD-10 site)license: approvedUS Government work (public domain) subject to CDC WONDER data use restrictions (statistical reporting only; counts ≤ 9 must not be published; no re-identification)
Age-standardized rates use the 2000 U.S. standard population (19 age groups); they are not comparable with rates standardized to the World (Segi) population used by IARC. Global comparisons are not available: the IARC Global Cancer Observatory remains under license review and the SEER API awaits credentials (CLAUDE.md §10.3-10.4). Only geographies with licensed observations get a page; see /countries.
Data updated 22 days agoSource updated 1999–202410,680 observations approx. · ranks from snapshots geo=USA