Cancer Family
Stromal Neoplasm
CI-CAN-00000360Explore in graph →
Non-malignant52 active trials2 approved drugs89 evidence items
- NCIt
- C6781
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Cancer Family
CI-CAN-00000360Explore in graph →
Clinical trials
355 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05565066 | A Real-world Comparison of FNB and FNA in IHC-required Lesions. | completed | — | 439 | Huazhong University of Science and TechnologyOTHER | 1 | Dec 1, 2022 | clinicaltrials |
| NCT03353753 | Phase 3 Study of DCC-2618 vs Placebo in Advanced GIST Patients Who Have Been Treated With Prior Anticancer Therapies(INVICTUS) | completed | Phase 3 | 129 | Deciphera Pharmaceuticals, LLCINDUSTRY | 13 | Nov 21, 2022 |
| clinicaltrials |
| NCT00623831 | A Phase 1 Study of Mixed Bacteria Vaccine (MBV) in Patients With Tumors Expressing NY-ESO-1 Antigen | completed | Phase 1 | 17 | Ludwig Institute for Cancer ResearchOTHER | 1 | Oct 25, 2022 | clinicaltrials |
| NCT03465722 | (VOYAGER) Study of Avapritinib vs Regorafenib in Patients With Locally Advanced Unresectable or Metastatic GIST | completed | Phase 3 | 476 | Blueprint Medicines CorporationINDUSTRY | 18 | Oct 6, 2022 | clinicaltrials |
| NCT05408897 | Prediction of Postoperative Treatment Efficacy and Recurrence Risk of High-risk GIST Based on Liquid Biopsy MRD | recruiting | — | 45 | Peking University People's HospitalOTHER | 1 | Sep 21, 2022 | clinicaltrials |
| NCT02880020 | Nivolumab With or Without Ipilimumab in Treating Patients With Gastrointestinal Stromal Tumor That Is Metastatic or Cannot Be Removed by Surgery | completed | Phase 2 | 36 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Aug 18, 2022 | clinicaltrials |
| NCT02071862 | Study of the Glutaminase Inhibitor CB-839 in Solid Tumors | completed | Phase 1 | 210 | Calithera Biosciences, IncINDUSTRY | 1 | Jul 20, 2022 | clinicaltrials |
| NCT02508532 | (NAVIGATOR) Study of BLU-285 in Patients With Gastrointestinal Stromal Tumors (GIST) and Other Relapsed and Refractory Solid Tumors | completed | Phase 1 | 250 | Blueprint Medicines CorporationINDUSTRY | 10 | Jun 21, 2022 | clinicaltrials |
| NCT05400018 | Clinical Evaluation of Genetron D842V PCR Kit in GIST Patients | completed | — | 1,041 | Genetron HealthINDUSTRY | 1 | Jun 6, 2022 | clinicaltrials |
| NCT05354388 | Ripretinib Combined With Surgery in Advanced GIST That Have Failed Imatinib Therapy: A Multicenter,Observational Study | unknown | — | 30 | Sichuan Provincial People's HospitalOTHER | 1 | Apr 29, 2022 | clinicaltrials |
| NCT03404076 | Unifying Advanced Treatment With Advanced Imaging(GISTm3) | completed | — | 93 | Heidelberg UniversityOTHER | 1 | Apr 7, 2022 | clinicaltrials |
| NCT01933958 | Regorafenib Post-marketing Surveillance in Japan | completed | — | 72 | BayerINDUSTRY | 1 | Apr 1, 2022 | clinicaltrials |
| NCT04825470 | Liver Transplantation for Unresectable GIST Liver Metastases(TRANSGIST) | unknown | N/A | 50 | Hospital Universitario Virgen de la ArrixacaOTHER | 1 | Mar 11, 2022 | clinicaltrials |
| NCT02924714 | SSG XXV: The Stop-GIST Trial; Discontinuation of Imatinib in Patients With Oligo-metastatic GIST | suspended | N/A | 31 | Oslo University HospitalOTHER | 1 | Feb 18, 2022 | clinicaltrials |
| NCT05197933 | Safety of Laparoscopic Resection for Gastrointestinal Stromal Tumor on Unfavorable Anatomic Site of Stomach | unknown | N/A | 182 | RenJi HospitalOTHER | 1 | Jan 20, 2022 | clinicaltrials |
| NCT05080621 | Ripretinib in Combination With Binimetinib in Patients With Gastrointestinal Stromal Tumor (GIST) | withdrawn | Phase 1 / Phase 2 | 0 | Deciphera Pharmaceuticals, LLCINDUSTRY | 0 | Jan 5, 2022 | clinicaltrials |
| NCT04751591 | Study On Safety Of Endoscopic Resection For 2-5cm Gastric Gastrointestinal Stromal Tumor | unknown | N/A | 260 | Shanghai Zhongshan HospitalOTHER | 0 | Nov 30, 2021 | clinicaltrials |
| NCT05132738 | Ripretinib Used for Resectable Metastatic GIST After Failure of Imatinib Therapy | unknown | N/A | 20 | RenJi HospitalOTHER | 1 | Nov 24, 2021 | clinicaltrials |
| NCT04933669 | Prospective Multicenter Clinical Study of Neoadjuvant Imatinib Mesylate for Gastrointestinal Stromal Tumors(ZJGIST-01) | recruiting | Phase 2 | 122 | First Affiliated Hospital of Zhejiang UniversityOTHER | 1 | Oct 12, 2021 | clinicaltrials |
| NCT05001204 | 68Ga-NOTA-RM26 PET/CT for the Detection of Gastrointestinal Stromal Tumor | unknown | Early Phase 1 | 30 | Peking Union Medical College HospitalOTHER | 1 | Aug 11, 2021 | clinicaltrials |
| NCT02216578 | Ph II CABOGIST in GIST | completed | Phase 2 | 51 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 6 | Jul 15, 2021 | clinicaltrials |
| NCT01275222 | Everolimus in Combination With Imatinib in Patients With Glivec Refractory/Resistant Gastrointestinal Stromal Tumors | completed | Phase 1 / Phase 2 | 117 | Novartis PharmaceuticalsINDUSTRY | 4 | Jun 25, 2021 | clinicaltrials |
| NCT02164240 | Phase Ib Study of SUnitinib Alternating With REgorafenib in Patients With Metastatic and/or Unresectable GIST(SURE) | completed | Phase 1 | 14 | Dana-Farber Cancer InstituteOTHER | 1 | Jun 14, 2021 | clinicaltrials |
| NCT03158103 | A Study of MEK162 (Binimetinib) in Combination With Pexidartinib in Patients With Advanced Gastrointestinal Stromal Tumor (GIST) | completed | Phase 1 | 3 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Apr 30, 2021 | clinicaltrials |
| NCT04761172 | NIR Fluorescence Imaging With ICG for the Intraoperative Identification of Gastrointestinal Stromal Cell Tumours | unknown | Phase 2 / Phase 3 | 10 | Leiden University Medical CenterOTHER | 1 | Feb 18, 2021 | clinicaltrials |
| NCT01271712 | Study of Regorafenib as a 3rd-line or Beyond Treatment for Gastrointestinal Stromal Tumors (GIST)(GRID) | completed | Phase 3 | 199 | BayerINDUSTRY | 17 | Jan 29, 2021 | clinicaltrials |
| NCT00135005 | Study of AMN107 With Imatinib in Gastrointestinal Stromal Tumors (GIST) | completed | Phase 1 | 59 | Novartis PharmaceuticalsINDUSTRY | 4 | Dec 8, 2020 | clinicaltrials |
| NCT01694277 | Masitinib in Patients With Gastrointestinal Stromal Tumour After Progression With Imatinib | completed | Phase 3 | 258 | AB ScienceINDUSTRY | 4 | Dec 8, 2020 | clinicaltrials |
| NCT02185937 | Influence of an Acidic Beverage on the Imatinib Exposure After Major Gastrectomy(ABILITY) | terminated | Phase 1 | 5 | Radboud University Medical CenterOTHER | 1 | Dec 8, 2020 | clinicaltrials |
| NCT03896958 | The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)(PIONEER) | unknown | — | 1,000 | SpeciCareINDUSTRY | 1 | Dec 4, 2020 | clinicaltrials |
| NCT00028002 | Neoadjuvant and Adjuvant Imatinib Mesylate in Treating Patients With Primary or Recurrent Malignant Gastrointestinal Stromal Tumor | completed | Phase 2 | 63 | National Cancer Institute (NCI)NIH | 1 | Oct 26, 2020 | clinicaltrials |
| NCT00510354 | Treatment of Patients With Everolimus and Imatinib Mesylate Who Have Progressive Gastro Intestinal Stromal Tumors (GIST) and Are Resistant to Imatinib Mesylate(Radix) | completed | Phase 4 | 28 | Novartis PharmaceuticalsINDUSTRY | 1 | Sep 10, 2020 | clinicaltrials |
| NCT01068769 | Regorafenib in Patients With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor | completed | Phase 2 | 34 | Suzanne George, MDOTHER | 1 | Aug 24, 2020 | clinicaltrials |
| NCT03880617 | Distress, Medication Adherence and Care Needs in Patients With CML and GIST Receiving Oral Targeted Therapy | completed | — | 297 | National Taiwan University HospitalOTHER | 1 | Aug 10, 2020 | clinicaltrials |
| NCT03862885 | Early Access Program (EAP) for Avapritinib in Patients With Locally Advanced Unresectable or Metastatic GIST | approved for marketing | — | — | Blueprint Medicines CorporationINDUSTRY | 0 | Jul 27, 2020 | clinicaltrials |
| NCT03426722 | L-carnitine vs Placebo for the Treatment of Muscle Cramps After Imatinib in Gastrointestinal Stromal Tumors | completed | Phase 3 | 4 | Asan Medical CenterOTHER | 1 | Jul 13, 2020 | clinicaltrials |
| NCT04256226 | Clinical Outcome of Female Non-gastric Gastrointestinal Stromal Tumor | completed | — | 26 | Far Eastern Memorial HospitalOTHER | 1 | Jun 2, 2020 | clinicaltrials |
| NCT04148092 | Expanded Access Program of Ripretinib (DCC-2618) for the Treatment of Patients With Advanced GIST | approved for marketing | — | — | Deciphera Pharmaceuticals, LLCINDUSTRY | 0 | May 29, 2020 | clinicaltrials |
| NCT04143048 | A Study on Non-invasive Early Diagnosis of Gastrointestinal Stromal Tumors and Differentiation of Benign and Malignant Nodules | unknown | — | 300 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | May 11, 2020 | clinicaltrials |
| NCT04343456 | Salvage Surgery for Patients With Metastatic GIST With Rego | completed | — | 41 | Chang Gung Memorial HospitalOTHER | 1 | Apr 14, 2020 | clinicaltrials |
| NCT00718211 | A Retrospective Clinical Records Review of Patients Diagnosed With Gastrointestinal Stromal Tumour at Two Tertiary Institutes in Singapore | completed | — | — | National University Hospital, SingaporeOTHER | 1 | Mar 30, 2020 | clinicaltrials |
| NCT02015065 | Phase II Trial of Vandetanib in Children and Adults With Wild-Type Gastrointestinal Stromal Tumors | completed | Phase 2 | 9 | National Cancer Institute (NCI)NIH | 1 | Mar 30, 2020 | clinicaltrials |
| NCT02257541 | BGJ398 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST) | completed | Phase 1 / Phase 2 | 16 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Mar 30, 2020 | clinicaltrials |
| NCT02452424 | A Combination Clinical Study of PLX3397 and Pembrolizumab To Treat Advanced Melanoma and Other Solid Tumors | terminated | Phase 1 / Phase 2 | 78 | Daiichi SankyoINDUSTRY | 1 | Mar 5, 2020 | clinicaltrials |
| NCT04269941 | Prognostic Factors Affecting Survival of Gastric GIST | completed | — | 34 | Université de SousseOTHER | 0 | Feb 17, 2020 | clinicaltrials |
| NCT01440959 | Dovitinib for Imatinib/Sumitinib-failed Gastrointestinal Stromal Tumors (GIST): TKI258 | completed | Phase 2 | 30 | Asan Medical CenterOTHER | 1 | Jan 18, 2020 | clinicaltrials |
| NCT01151852 | Rechallenge of Imatinib in GIST Having no Effective Treatment: RIGHT | completed | Phase 3 | 81 | Asan Medical CenterOTHER | 1 | Jan 14, 2020 | clinicaltrials |
| NCT01178307 | Symptom Inventory for Gastrointestinal Stromal Tumors | unknown | — | 187 | M.D. Anderson Cancer CenterOTHER | 1 | Jan 13, 2020 | clinicaltrials |
| NCT02889328 | Phase II Study of Regorafenib Continuous Dosing of Regorafenib in Patients With GISTs | completed | Phase 2 | 25 | Asan Medical CenterOTHER | 1 | Jan 9, 2020 | clinicaltrials |
| NCT00278876 | Adjuvant Imatinib in High-risk Gastrointestinal Stromal Tumor (GIST) With C-kit Mutation | completed | Phase 2 | 47 | Asan Medical CenterOTHER | 1 | Jan 7, 2020 | clinicaltrials |
Data updated 22 days agoSource updated Dec 1, 2022source: clinicaltrials