Cancer Family
Squamous Cell Neoplasm
CI-CAN-00000359Explore in graph →
Non-malignant1,024 active trials9 approved drugs78 evidence items
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Cancer Family
CI-CAN-00000359Explore in graph →
Genomics
26 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
40 cases with simple somatic mutation data · 40 cases total · 2026-01-07 · mapped to Head and Neck Squamous Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| TP53 |
| Ssm |
| 19 |
| 40 |
| 47.5% |
| cbioportal |
| 2 | TTN | Ssm | 5 | 40 | 12.5% | cbioportal |
| 3 | FAT1 | Ssm | 4 | 40 | 10% | cbioportal |
| 4 | OR2T35 | Ssm | 4 | 40 | 10% | cbioportal |
| 6 | EPHA7 | Ssm | 3 | 40 | 7.5% | cbioportal |
| 8 | RYR2 | Ssm | 3 | 40 | 7.5% | cbioportal |
| 7 | GPRIN2 | Ssm | 3 | 40 | 7.5% | cbioportal |
| 5 | ARHGAP29 | Ssm | 3 | 40 | 7.5% | cbioportal |
| 11 | ACSF3 | Ssm | 2 | 40 | 5% | cbioportal |
| 18 | COL11A1 | Ssm | 2 | 40 | 5% | cbioportal |
| 19 | CRABP2 | Ssm | 2 | 40 | 5% | cbioportal |
| 20 | CSMD3 | Ssm | 2 | 40 | 5% | cbioportal |
| 21 | DCC | Ssm | 2 | 40 | 5% | cbioportal |
| 22 | DMKN | Ssm | 2 | 40 | 5% | cbioportal |
| 23 | DSC1 | Ssm | 2 | 40 | 5% | cbioportal |
| 24 | EGFR | Ssm | 2 | 40 | 5% | cbioportal |
| 25 | EPG5 | Ssm | 2 | 40 | 5% | cbioportal |
| 26 | ERICH3 | Ssm | 2 | 40 | 5% | cbioportal |
| 27 | GALNT14 | Ssm | 2 | 40 | 5% | cbioportal |
| 28 | GDF2 | Ssm | 2 | 40 | 5% | cbioportal |
| 29 | HCRTR2 | Ssm | 2 | 40 | 5% | cbioportal |
| 30 | HLA-B | Ssm | 2 | 40 | 5% | cbioportal |
| 31 | ITGB4 | Ssm | 2 | 40 | 5% | cbioportal |
| 32 | ITGB7 | Ssm | 2 | 40 | 5% | cbioportal |
| 33 | KALRN | Ssm | 2 | 40 | 5% | cbioportal |
| 34 | KCNJ12 | Ssm | 2 | 40 | 5% | cbioportal |
| 35 | KDM3B | Ssm | 2 | 40 | 5% | cbioportal |
| 36 | LRP1B | Ssm | 2 | 40 | 5% | cbioportal |
| 37 | LRP8 | Ssm | 2 | 40 | 5% | cbioportal |
| 38 | MAGEC1 | Ssm | 2 | 40 | 5% | cbioportal |
Data updated 22 days agoSource updated 2026-01-07