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CancerIndex

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Reproductive System Neoplasm — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Site
Genitourinary System Neoplasm
Reproductive System Neoplasm

Cancer Family

Reproductive System Neoplasm

CI-CAN-00000338Explore in graph →

Non-malignant3,042 active trials38 approved drugs197 evidence items

NCIt: C3674

Overview
Statistics
Survival
Genomics65
Variants & evidence197
Drugs58
Trials13672
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

What CancerIndex knows

Trials tab
Methodology: publication counts

Literature

Linked publications (625)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 576–600 of 625 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

Expression of p16 and retinoblastoma determines response to CDK4/6 inhibition in ovarian cancer.
· Clin Cancer Res · 2011 · PMID 21278246 · validated civic_curation pubmed
Feedback suppression of PI3Kα signaling in PTEN-mutated tumors is relieved by selective inhibition of PI3Kβ.
· Cancer Cell · 2015 · PMID 25544636 · validated civic_curation pubmed
PI3K pathway dependencies in endometrioid endometrial cancer cell lines.
· Clin Cancer Res · 2013 · PMID 23674493 · validated civic_curation pubmed
Growth Arrest-Specific 6 (GAS6) Promotes Prostate Cancer Survival by G1 Arrest/S Phase Delay and Inhibition of Apoptosis During Chemotherapy in Bone Marrow.
· J Cell Biochem · 2016 · PMID 27153245 · validated civic_curation pubmed
hVps37A Status affects prognosis and cetuximab sensitivity in ovarian cancer.
· Clin Cancer Res · 2011 · PMID 22016507 · validated civic_curation pubmed
Phosphatidyl inositol-3 kinase (PIK3CA) E545K mutation confers cisplatin resistance and a migratory phenotype in cervical cancer cells.
· Oncotarget · 2016 · PMID 27489350 · validated civic_curation pubmed
Cetuximab inhibits the growth of mucinous ovarian carcinoma tumor cells lacking KRAS gene mutations.
· Oncol Rep · 2012 · PMID 22246397 · validated civic_curation pubmed

Showing 576–600 of 625 publications

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Epigenetic silencing of argininosuccinate synthetase confers resistance to platinum-induced cell death but collateral sensitivity to arginine auxotrophy in ovarian cancer.

· Int J Cancer · 2009 · PMID 19533750 · validated civic_curation pubmed

Targeting CCNE1 amplified ovarian and endometrial cancers by combined inhibition of PKMYT1 and ATR.

· Nat Commun · 2025 · PMID 40169546 · validated civic_curation pubmed

Loss of STK11 expression is an early event in prostate carcinogenesis and predicts therapeutic response to targeted therapy against MAPK/p38.

· Autophagy · 2015 · PMID 26391455 · validated civic_curation pubmed

Effect of MRE11 loss on PARP-inhibitor sensitivity in endometrial cancer in vitro.

· PLoS One · 2014 · PMID 24927325 · validated civic_curation pubmed

Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells.

· Mol Cancer Ther · 2006 · PMID 17088436 · validated civic_curation pubmed

Downregulation of cytokeratin 18 is associated with paclitaxel‑resistance and tumor aggressiveness in prostate cancer.

· Int J Oncol · 2016 · PMID 26892177 · validated civic_curation pubmed

Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line.

· Gynecol Oncol · 2005 · PMID 15790433 · validated civic_curation pubmed

Cyclin-dependent kinase 2 is an ideal target for ovary tumors with elevated cyclin E1 expression.

· Oncotarget · 2015 · PMID 26204491 · validated civic_curation pubmed

BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one functionally deleterious BRCA1 mutation.

· Mol Oncol · 2013 · PMID 23415752 · validated civic_curation pubmed

Elkin et al. NPJ Genome Med 2021

· 2021 · PMID 34819508 · validated cbioportal_study pubmed

Manning-Geist et al. Clin Cancer Res. 2022

· 2022 · PMID 35443055 · validated cbioportal_study pubmed

Beltran et al. Nat Med 2016

· 2016 · PMID 26855148 · validated cbioportal_study pubmed

TCGA, Nature 2011

· 2011 · PMID 21720365 · validated cbioportal_study pubmed

Barbieri et al. Nat Genet 2012

· 2012 · PMID 22610119 · validated cbioportal_study pubmed

Baca et al. Cell 2013

· 2013 · PMID 23622249 · validated cbioportal_study pubmed

Nguyen et al. Eur Urol 2020

· 2020 · PMID 32317181 · validated cbioportal_study pubmed

Fraser et al. Nature 2017

· 2017 · PMID 28068672 · validated cbioportal_study pubmed

Shancheng et al. Eur Urol 2017

· 2017 · PMID 28927585 · validated cbioportal_study pubmed