Subtype
Renal Cell Carcinoma
CI-CAN-00006578RCCExplore in graph →
375 active trials17 approved drugs60 evidence items
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Subtype
CI-CAN-00006578RCCExplore in graph →
Genomics
24 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
943 cases with simple somatic mutation data · 943 cases total · 2026-03-09 · mapped to Clear Cell Renal Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | VHL |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 642 |
| 943 |
| 68.1% |
| cbioportal |
| 2 | PBRM1 | Ssm | 325 | 943 | 34.5% | cbioportal |
| 3 | SETD2 | Ssm | 151 | 943 | 16% | cbioportal |
| 4 | BAP1 | Ssm | 119 | 943 | 12.6% | cbioportal |
| 5 | KDM5C | Ssm | 67 | 943 | 7.1% | cbioportal |
| 6 | ATM | Ssm | 31 | 943 | 3.3% | cbioportal |
| 8 | TP53 | Ssm | 29 | 943 | 3.1% | cbioportal |
| 7 | DMD | Ssm | 29 | 943 | 3.1% | cbioportal |
| 9 | COL11A1 | Ssm | 21 | 943 | 2.2% | cbioportal |
| 10 | TRRAP | Ssm | 12 | 943 | 1.3% | cbioportal |
| 11 | PTK7 | Ssm | 6 | 943 | 0.6% | cbioportal |
| 12 | ATP9B | Ssm | 5 | 943 | 0.5% | cbioportal |
Data updated 21 days agoSource updated 2026-03-09