Subtype
Primary Central Nervous System Neoplasm
CI-CAN-00001432Explore in graph →
Non-malignant957 active trials5 approved drugs175 evidence items
- NCIt
- C102871
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Subtype
CI-CAN-00001432Explore in graph →
Clinical trials
3,293 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05802693 | A Study to Evaluate the Safety, Tolerance and Initial Efficacy of EGFRvIII CAR-T on Glioblastoma | unknown | Early Phase 1 | 22 | Beijing Tsinghua Chang Gung HospitalOTHER | 0 | Aug 25, 2023 | clinicaltrials |
| NCT05984108 | Clinical, Radiological, Histologic and Molecular Features of a Cohort of Melanocytic Tumors of the Central Nervous System(MelaMen) | unknown | — | 50 | Central Hospital, Nancy, FranceOTHER | 1 |
| Aug 9, 2023 |
| clinicaltrials |
| NCT04532229 | Nimotuzumab in Combined With Chemoradiotherapy to Treat the Newly Diagnosed Diffuse Intrinsic Pontine Glioma in Children | unknown | Phase 3 | 48 | Biotech Pharmaceutical Co., Ltd.OTHER | 1 | Jul 27, 2023 | clinicaltrials |
| NCT05958472 | Navigating the Clinical Research Process for Glioma | unknown | — | 500 | Power Life Sciences Inc.INDUSTRY | 1 | Jul 24, 2023 | clinicaltrials |
| NCT05958485 | A Close Examination of Patient Experiences in Glioblastoma Multiforme Clinical Research | unknown | — | 500 | Power Life Sciences Inc.INDUSTRY | 1 | Jul 24, 2023 | clinicaltrials |
| NCT05950490 | Construction of Diagnosis and Treatment System for Primary Vitreoretinal Lymphoma | unknown | — | 100 | Peking Union Medical College HospitalOTHER | 1 | Jul 18, 2023 | clinicaltrials |
| NCT05635435 | Immune and Inflammatory Indices in Peripheral Blood Predict Prognosis of Glioma and Correlate With Grades and Subtypes | unknown | — | 1,282 | Sun Yat-sen UniversityOTHER | 1 | Jul 12, 2023 | clinicaltrials |
| NCT04967690 | A Dose Escalation Study to Estimate MTD, DLTs and Pharmacokinetics After a Single Intracranial Dose of SI-053 as an add-on to the Current Standard of Care, in Adult Patients With Newly Diagnosed GBM(TARGLIO) | unknown | Phase 1 | 27 | Double Bond Pharmaceutical ABINDUSTRY | 0 | Jul 6, 2023 | clinicaltrials |
| NCT05929456 | Multispectral Bimodal Fluorescence Guided Surgery of High-grade Glioma With Cetuximab-800CW and 5-ALA (5-aminolevulinic Acid)(MIRROR) | unknown | Phase 1 | 21 | University Medical Center GroningenOTHER | 1 | Jul 3, 2023 | clinicaltrials |
| NCT04671459 | TTFields and Radiosurgery of Recurrent Glioblastoma +/- 18F-Fluoro-Ethyl-Thyrosine(TaRRGET) | unknown | Phase 2 | 40 | Prof. Franciszek Lukaszczyk Memorial Oncology CenterOTHER | 1 | Jun 28, 2023 | clinicaltrials |
| NCT05901844 | Evaluate the Accuracy of Raman IVD Analyzer in the Diagnosis of Gliomas During Surgery | unknown | N/A | 256 | Beijing Tiantan HospitalOTHER | 0 | Jun 13, 2023 | clinicaltrials |
| NCT05191784 | GX-I7 in Combination With Bevacizumab in Recurrent Glioblastoma (GBM) Patients | unknown | Phase 2 | 20 | Genexine, Inc.INDUSTRY | 1 | Jun 12, 2023 | clinicaltrials |
| NCT05728125 | Pinpointing the Factors Affecting Clinical Trial Experiences of Glioblastoma Patients | unknown | — | 500 | Power Life Sciences Inc.INDUSTRY | 0 | Jun 12, 2023 | clinicaltrials |
| NCT04223999 | Improving Tumor Treating Fields Treatment for Brain Cancer Patients With Skullremodeling Surgery (Neurosurgery)(OptimalTTF-2) | unknown | Phase 2 | 70 | Anders Rosendal KorshøjOTHER | 1 | Jun 6, 2023 | clinicaltrials |
| NCT03411408 | Accelerated Hypofractionated Intensity - Modulated Radiotherapy After Hyperbaric Oxygenation for Recurrent High Grade Glioma.(HBO-RT) | unknown | N/A | 24 | Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCSOTHER | 1 | May 30, 2023 | clinicaltrials |
| NCT05764460 | Social Cognition and Language in Patients With Gliomas | unknown | — | 105 | University Medical Center GroningenOTHER | 0 | May 17, 2023 | clinicaltrials |
| NCT05850377 | 5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas | unknown | — | 90 | Sociedad de Lucha Contra el Cáncer del EcuadorOTHER | 1 | May 9, 2023 | clinicaltrials |
| NCT02137759 | MRSI to Predict Response to RT/TMZ ± Belinostat in GBM | unknown | Phase 2 | 29 | Emory UniversityOTHER | 1 | May 6, 2023 | clinicaltrials |
| NCT05803057 | Accelerating Motor Recovering in Patients With SMA Syndrome After Glioma Surgery by Using nrTMS | unknown | N/A | 64 | Beijing Neurosurgical InstituteOTHER | 1 | May 3, 2023 | clinicaltrials |
| NCT03534050 | Neuropsychological and Oncological Outcomes in Grade 2 or 3 Glioma Patients Undergoing Postoperative Modern Radiotherapy | unknown | Phase 2 / Phase 3 | 80 | Chang Gung Memorial HospitalOTHER | 1 | May 1, 2023 | clinicaltrials |
| NCT04712214 | Use of Non-invasive Optical Analysis in Neurosurgery | unknown | N/A | 50 | Imperial College LondonOTHER | 1 | Apr 25, 2023 | clinicaltrials |
| NCT04359745 | Improving Treatment of Glioblastoma: Distinguishing Progression From Pseudoprogression | unknown | — | 500 | Guy's and St Thomas' NHS Foundation TrustOTHER | 1 | Apr 21, 2023 | clinicaltrials |
| NCT05821790 | Role of the Tumor Microenvironment in Aggressive Meningiomas(MEME) | unknown | — | 40 | Assistance Publique - Hôpitaux de ParisOTHER | 0 | Apr 20, 2023 | clinicaltrials |
| NCT05363826 | Intracavitary Photodynamic Therapy as an Adjuvant to Resection of Glioblastoma or Gliosarcoma Using IV Photobac® | unknown | Phase 1 | 30 | Photolitec LLCINDUSTRY | 1 | Apr 13, 2023 | clinicaltrials |
| NCT05811793 | Efficacy and Safety of SCAI of Bevacizumab Combined With IC of Tislelizumab in the Treatment of Recurrent Glioblastoma. | unknown | N/A | 36 | Second Affiliated Hospital of Nanchang UniversityOTHER | 0 | Apr 13, 2023 | clinicaltrials |
| NCT05793021 | FKBP51s: a New Molecular Biomarker for Glioblastoma? Pre- and Post-operative Blood Levels Evaluation of FKBP51s Protein and Correlation With MRI Phenotype | unknown | N/A | 70 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 31, 2023 | clinicaltrials |
| NCT01672463 | Clinical Trial of IV OKN-007 in a Pilot Cohort of Human Recurrent Malignant Glioma Patients(OKN-007) | unknown | Phase 1 | 31 | Oblato, Inc.INDUSTRY | 1 | Mar 29, 2023 | clinicaltrials |
| NCT05788445 | High-frequency nrTMS on the Contralateral Broca Mirror Area for Glioma Patients With Early Postoperative Aphasia | unknown | N/A | 48 | Beijing Neurosurgical InstituteOTHER | 0 | Mar 28, 2023 | clinicaltrials |
| NCT03561207 | 3D Prediction of Patient-Specific Response(3D-PREDICT) | unknown | — | 570 | KIYATECINDUSTRY | 1 | Mar 24, 2023 | clinicaltrials |
| NCT05772741 | Grafts of GSCs Into Brain Organoids for Testing Anti-invasion Drugs(2253) | unknown | N/A | 160 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 16, 2023 | clinicaltrials |
| NCT05752877 | Safety and Efficacy of Targeted IL-13 Rα2 or B7-H3 UCAR-T for Advanced Glioma | unknown | N/A | 12 | Second Affiliated Hospital of Soochow UniversityOTHER | 1 | Mar 3, 2023 | clinicaltrials |
| NCT05739500 | MRI-based Computer Aided Diagnosis Software (V1) for Glioma | unknown | — | 250 | Mingge LLCINDUSTRY | 1 | Feb 22, 2023 | clinicaltrials |
| NCT05737368 | Treatment of Recurrent Glioblastoma With Fractionated Radiotherapy Combined With Cadonilimab | unknown | Phase 1 | 11 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 0 | Feb 21, 2023 | clinicaltrials |
| NCT05707728 | Evaluation of Role of Intraoperative Ultrasound in Gross Total Resection of Gliomas | unknown | — | 45 | Assiut UniversityOTHER | 0 | Feb 8, 2023 | clinicaltrials |
| NCT04642937 | Study of CD200 Activation Receptor Ligand (CD200AR-L) and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent Glioblastoma | unknown | Phase 1 | 24 | OX2 TherapeuticsINDUSTRY | 1 | Jan 27, 2023 | clinicaltrials |
| NCT05700955 | Neoadjuvant Chemoimmunotherapy in Recurrent Glioblastoma | unknown | Phase 1 | 30 | University of LouisvilleOTHER | 1 | Jan 26, 2023 | clinicaltrials |
| NCT05694416 | Etoposide Plus Cisplatin Compared With Temozolomide in Patients With Glioblastoma | unknown | Phase 2 | 60 | Zhongnan HospitalOTHER | 0 | Jan 23, 2023 | clinicaltrials |
| NCT04840069 | Radiotherapy Planning Using Fluciclovine PET in Patients With Newly Diagnosed Glioblastoma | unknown | Phase 2 | 100 | St. Joseph's Hospital and Medical Center, PhoenixOTHER | 1 | Jan 13, 2023 | clinicaltrials |
| NCT04908267 | How the Precise Habitats Can Predict the IDH Mutation Status and Prognosis of the Patients With High-grade Gliomas | unknown | — | 100 | Weiguo ZhangOTHER | 1 | Jan 11, 2023 | clinicaltrials |
| NCT04717739 | TIGER PRO-Active - Daily Activity, Sleep and Neurocognitive Functioning Study | unknown | — | 500 | NovoCure Ltd.INDUSTRY | 1 | Jan 10, 2023 | clinicaltrials |
| NCT05540873 | A Clinical Study of IL13Rα2 Targeted CAR-T in Patients With Malignant Glioma (MAGIC-I) | unknown | Phase 1 | 18 | CellabMEDINDUSTRY | 1 | Jan 6, 2023 | clinicaltrials |
| NCT04077866 | B7-H3 CAR-T for Recurrent or Refractory Glioblastoma | unknown | Phase 1 / Phase 2 | 40 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Dec 28, 2022 | clinicaltrials |
| NCT04385173 | Pilot Study of B7-H3 CAR-T in Treating Patients With Recurrent and Refractory Glioblastoma | unknown | Phase 1 | 12 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Dec 28, 2022 | clinicaltrials |
| NCT05663125 | LITT Combined With Early Use of Temozolomide for Recurrent Glioblastomas | unknown | Phase 1 / Phase 2 | 10 | Beijing Tiantan HospitalOTHER | 1 | Dec 23, 2022 | clinicaltrials |
| NCT05656300 | Glioblastoma Imaging Using a Strong Iron-like Bloodpool Contrast Medium? | unknown | — | 15 | Radboud University Medical CenterOTHER | 0 | Dec 19, 2022 | clinicaltrials |
| NCT05630664 | Liquid Biopsy in High-grade Gliomas and Meningiomas(SOPRANO) | unknown | — | 90 | IRCCS San RaffaeleOTHER | 1 | Dec 2, 2022 | clinicaltrials |
| NCT05624736 | Hierarchical Diagnosis for Adult Diffuse Glioma Based on Deep Learning | unknown | — | 500 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolOTHER | 1 | Nov 22, 2022 | clinicaltrials |
| NCT05611645 | Low-dose Bevacizumab With HSRT vs BVZ Alone for GBM at First Recurrence | unknown | Phase 2 | 42 | Huashan HospitalOTHER | 1 | Nov 10, 2022 | clinicaltrials |
Data updated 23 days agoSource updated Aug 25, 2023source: clinicaltrials