Cancer Family
Nervous System Neoplasm
CI-CAN-00000038Explore in graph →
Non-malignant1,523 active trials9 approved drugs210 evidence items
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Cancer Family
CI-CAN-00000038Explore in graph →
Clinical trials
5,871 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05851378 | Hyperpolarized Carbon-13 Alpha-ketoglutarate Imaging in IDH Mutant Glioma | completed | Early Phase 1 | 13 | Robert Bok, MD, PhDOTHER | 1 | Aug 12, 2026 | clinicaltrials |
| NCT03542409 | Safety and Feasibility of Preoperative and Intraoperative Image-Guided Resection of Gliomas | completed | Early Phase 1 | 53 | University of UtahOTHER | 1 | Aug 10, 2026 | clinicaltrials |
| Expedited Laser Interstitial Thermal Therapy + Chemoradiation For Newly Diagnosed High Grade Gliomas |
| completed |
| Early Phase 1 |
| 13 |
| Case Comprehensive Cancer CenterOTHER |
| 1 |
| Aug 6, 2026 |
| clinicaltrials |
| NCT04614909 | Study of Pamiparib in Newly Diagnosed and rGBM | completed | Early Phase 1 | 50 | Nader SanaiOTHER | 1 | May 14, 2026 | clinicaltrials |
| NCT04895592 | Radiosurgery Before Surgery for the Treatment of Brain Metastases | completed | Early Phase 1 | 26 | Emory UniversityOTHER | 1 | May 14, 2026 | clinicaltrials |
| NCT05704933 | Pilot Study of Nivolumab w/Ipilimumab or Relatlimab in Surgically Resectable Melanoma Brain Metastases | completed | Early Phase 1 | 1 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Apr 6, 2026 | clinicaltrials |
| NCT05577416 | A Study of AB-218 in Patients With IDH1 Mutated Low Grade Glioma(AB-218-IIT-201) | completed | Early Phase 1 | 14 | Melbourne HealthOTHER | 1 | Mar 18, 2026 | clinicaltrials |
| NCT04391595 | LY3214996 Plus Abemaciclib in Recurrent Glioblastoma Patients | completed | Early Phase 1 | 42 | Nader SanaiOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT04173104 | PET and MRI Imaging of Brain Tumors Using [18F]PARPi | completed | Early Phase 1 | 5 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 9, 2026 | clinicaltrials |
| NCT05432375 | Study of Tinostamustine for Adjuvant Treatment of Glioblastoma | completed | Early Phase 1 | 10 | Mundipharma Research LimitedINDUSTRY | 2 | Dec 10, 2025 | clinicaltrials |
| NCT02245997 | Local Control With Reduced-dose Radiotherapy for High-Risk Neuroblastoma | completed | Early Phase 1 | 78 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Sep 29, 2025 | clinicaltrials |
| NCT01165632 | Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma | completed | Early Phase 1 | 24 | Mayo ClinicOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT03834740 | A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection | completed | Early Phase 1 | 27 | St. Joseph's Hospital and Medical Center, PhoenixOTHER | 1 | May 30, 2025 | clinicaltrials |
| NCT03477110 | Temozolomide, Radiation Therapy, and Tumor Treating Fields Therapy in Treating Participants With Glioblastoma | completed | Early Phase 1 | 30 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT04315064 | Infusion of Panobinostat (MTX110) Into the Fourth Ventricle in Children and Adults with Recurrent Medulloblastoma | completed | Early Phase 1 | 2 | The University of Texas Health Science Center, HoustonOTHER | 1 | Mar 10, 2025 | clinicaltrials |
| NCT02992015 | Gemcitabine in Newly-Diagnosed Diffuse Intrinsic Pontine Glioma | completed | Early Phase 1 | 2 | University of Colorado, DenverOTHER | 1 | Mar 7, 2025 | clinicaltrials |
| NCT02020720 | 18F-DOPA-PET in Planning Surgery in Patients With Gliomas | completed | Early Phase 1 | 72 | Mayo ClinicOTHER | 1 | Jan 23, 2025 | clinicaltrials |
| NCT02901925 | A Microdose Evaluation Study of ABY-029 in Recurrent Glioma(ABY-029) | completed | Early Phase 1 | 14 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | Dec 13, 2024 | clinicaltrials |
| NCT04217694 | Memantine for the Reduction of Cognitive Impairment After Radiation Therapy in Pediatric Patients With Central Nervous System Tumors | completed | Early Phase 1 | 18 | Mayo ClinicOTHER | 1 | Nov 21, 2024 | clinicaltrials |
| NCT03995706 | Neuro/Sacituzumab Govitecan/Breast Brain Metastasis/Glioblastoma/Ph 0 | completed | Early Phase 1 | 26 | The University of Texas Health Science Center at San AntonioOTHER | 1 | Sep 4, 2024 | clinicaltrials |
| NCT04067960 | Pharmacogenomics Testing in the Optimal Use of Supportive Care Medications in Stage III-IV Cancer | completed | Early Phase 1 | 197 | Mayo ClinicOTHER | 1 | Aug 14, 2024 | clinicaltrials |
| NCT05977738 | Repurposed Drugs in Research for Cancer Clinical Trials- Pitavastatin(ReDiReCCT-Pita) | completed | Early Phase 1 | 12 | C.DirvenOTHER | 1 | Aug 7, 2024 | clinicaltrials |
| NCT04937413 | The PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics Evaluation | completed | Early Phase 1 | 32 | Duke UniversityOTHER | 1 | Jun 25, 2024 | clinicaltrials |
| NCT04752267 | 18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases | completed | Early Phase 1 | 10 | University of Southern CaliforniaOTHER | 1 | May 24, 2024 | clinicaltrials |
| NCT03454295 | Easing Psychosocial Burden for Informal Caregivers | completed | Early Phase 1 | 64 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Apr 1, 2024 | clinicaltrials |
| NCT02338037 | Neuropharmacokinetics of Eribulin Mesylate in Treating Patients With Primary or Metastatic Brain Tumors | completed | Early Phase 1 | 8 | City of Hope Medical CenterOTHER | 1 | Mar 19, 2024 | clinicaltrials |
| NCT04408092 | Study of the Effect of GM-CSF on Macrophages in Ependymoma | completed | Early Phase 1 | 6 | University of Colorado, DenverOTHER | 1 | Mar 15, 2024 | clinicaltrials |
| NCT01383135 | Biodistribution and Safety of the PET Probes [18F]FPRGD2 and [18F]FPPRGD2 | completed | Early Phase 1 | 27 | Stanford UniversityOTHER | 1 | Jan 12, 2024 | clinicaltrials |
| NCT01957956 | Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma | completed | Early Phase 1 | 21 | Mayo ClinicOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT03360708 | Vaccine Therapy in Treating Patients With Recurrent Glioblastoma | completed | Early Phase 1 | 20 | Mayo ClinicOTHER | 1 | Jun 28, 2023 | clinicaltrials |
| NCT03250520 | Application of Palliative Treatment in Children With Brain Stem Glioma and Recurrent High-grade Tumors in the Central Nervous System With the Nanomaterial NPt-Ca | completed | Early Phase 1 | 8 | Hospital Infantil de Mexico Federico GomezOTHER | 1 | Feb 28, 2023 | clinicaltrials |
| NCT04114370 | Evaluation of 18F-fluciclovine (FACBC) PET/MR Uptake in Participants With Glioma(FACBC) | completed | Early Phase 1 | 9 | James MountzOTHER | 1 | Dec 6, 2022 | clinicaltrials |
| NCT03020017 | NU-0129 in Treating Patients With Recurrent Glioblastoma or Gliosarcoma Undergoing Surgery | completed | Early Phase 1 | 8 | Northwestern UniversityOTHER | 1 | Aug 26, 2022 | clinicaltrials |
| NCT00978562 | DSC-MRI With Ferumoxytol and DCE-MRI With Gadolinium in Imaging Vascular Properties in Younger Patients With Brain Tumors | completed | Early Phase 1 | 14 | OHSU Knight Cancer InstituteOTHER | 1 | Aug 3, 2022 | clinicaltrials |
| NCT02885272 | FDG PET Imaging in Diagnosing Patients With Glioblastoma | completed | Early Phase 1 | 21 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 21, 2022 | clinicaltrials |
| NCT03291990 | 5 Fraction Stereotactic Radiosurgery With Temozolomide for Glioblastoma Multiforme | completed | Early Phase 1 | 3 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Nov 19, 2021 | clinicaltrials |
| NCT03930173 | 18F-Fluciclovine PET to Distinguish Tumor Progression From Radiation Necrosis | completed | Early Phase 1 | 18 | Case Comprehensive Cancer CenterOTHER | 1 | May 5, 2021 | clinicaltrials |
| NCT02630030 | Phase 0 Analysis of Ixazomib (MLN9708) in Patients With Glioblastoma | completed | Early Phase 1 | 3 | Emory UniversityOTHER | 1 | Mar 26, 2021 | clinicaltrials |
| NCT00863122 | Concentration and Activity of Lapatinib in Vestibular Schwannomas | completed | Early Phase 1 | 26 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Jan 12, 2021 | clinicaltrials |
| NCT02605746 | Preoperative Ceritinib (LDK378) in Glioblastoma Multiforme and CNS Metastasis | completed | Early Phase 1 | 10 | St. Joseph's Hospital and Medical Center, PhoenixOTHER | 1 | Dec 11, 2020 | clinicaltrials |
| NCT02207010 | A Phase 0 Study of AZD1775 in Recurrent GBM Patients | completed | Early Phase 1 | 20 | St. Joseph's Hospital and Medical Center, PhoenixOTHER | 1 | Dec 10, 2020 | clinicaltrials |
| NCT01880749 | Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas | completed | Early Phase 1 | 5 | NYU Langone HealthOTHER | 1 | May 13, 2020 | clinicaltrials |
| NCT00993057 | Efficiency of Two Glucose Sampling Protocols for Maintenance of Euglycemia | completed | Early Phase 1 | 120 | Northwestern UniversityOTHER | 1 | Dec 13, 2019 | clinicaltrials |
| NCT00795457 | Effects of Vaccinations With HLA-A2-Restricted Glioma Antigen-Peptides in Combination With Poly-ICLC for Adults With High-Risk WHO Grade II Astrocytomas and Oligo-Astrocytomas | completed | Early Phase 1 | 13 | Ian F. Pollack, M.D.OTHER | 1 | Aug 30, 2019 | clinicaltrials |
| NCT03885258 | Melatonin Replacement Therapy in Pinealectomized Patients | completed | Early Phase 1 | 5 | University of Sao PauloOTHER | 1 | Mar 21, 2019 | clinicaltrials |
| NCT02768389 | Feasibility Trial of the Modified Atkins Diet and Bevacizumab for Recurrent Glioblastoma | completed | Early Phase 1 | 18 | Case Comprehensive Cancer CenterOTHER | 1 | Mar 15, 2019 | clinicaltrials |
| NCT01907165 | Disulfiram in Treating Patients With Glioblastoma Multiforme After Radiation Therapy With Temozolomide | completed | Early Phase 1 | 21 | Washington University School of MedicineOTHER | 1 | Jul 20, 2018 | clinicaltrials |
| NCT01459237 | Effects of Hormone Stimulation on Brain Scans for Cushing s Disease | completed | Early Phase 1 | 30 | National Institute of Neurological Disorders and Stroke (NINDS)NIH | 1 | Jun 14, 2018 | clinicaltrials |
| NCT01091792 | Exploratory Study of the Modulation of the Immune System by VEGF Blockade in Patients With Glioblastoma Multiforme (GBM) | completed | Early Phase 1 | 13 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | May 25, 2018 | clinicaltrials |
| NCT00890786 | A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas | completed | Early Phase 1 | 27 | Children's Hospital Medical Center, CincinnatiOTHER | 1 | May 2, 2018 | clinicaltrials |
Data updated 22 days agoSource updated Aug 12, 2026source: clinicaltrials