Cancer Family
Nervous System Neoplasm
CI-CAN-00000038Explore in graph →
Non-malignant1,523 active trials9 approved drugs210 evidence items
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Cancer Family
CI-CAN-00000038Explore in graph →
Clinical trials
5,871 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04681677 | Recurrent GBM Treated With Neurosurgical Resection and IORT Using the Xoft Axxent eBx System and Bevacizumab(IORT) | terminated | Phase 2 | 12 | Xoft, Inc.INDUSTRY | 1 | Apr 26, 2024 | clinicaltrials |
| NCT05518942 | Effects of SMR Neurofeedback on Insomnia in Patients With Benign Brain Tumors | terminated | N/A | 5 | Taipei Medical UniversityOTHER | 1 | Apr 22, 2024 | clinicaltrials |
| NCT02085304 | Tumor Resection and Gliadel® Wafers, Followed by Temodar® With Standard Radiation or GammaKnife® for New GBM | terminated | Phase 1 / Phase 2 | 8 | St. Joseph's Hospital and Medical Center, PhoenixOTHER | 1 | Apr 19, 2024 | clinicaltrials |
| NCT02386241 | Identification of Genomic Changes in Families Having Multiple Members With Tumors | terminated | — | 4 | St. Joseph's Hospital and Medical Center, PhoenixOTHER | 1 | Apr 19, 2024 | clinicaltrials |
| NCT02880410 | Feasibility Study on LITT for Newly Diagnosed Glioblastoma(FLAG) | terminated | Phase 1 | 3 | Monteris MedicalINDUSTRY | 1 | Apr 12, 2024 | clinicaltrials |
| NCT03927222 | Immunotherapy Targeted Against Cytomegalovirus in Patients With Newly-Diagnosed WHO Grade IV Unmethylated Glioma(I-ATTAC) | terminated | Phase 2 | 6 | Mustafa Khasraw, MBChB, MD, FRCP, FRACPOTHER | 1 | Apr 8, 2024 | clinicaltrials |
| NCT02133183 | Sapanisertib Before and After Surgery in Treating Patients With Recurrent Glioblastoma | terminated | Phase 1 | 40 | National Cancer Institute (NCI)NIH | 1 | Apr 4, 2024 | clinicaltrials |
| NCT04556929 | Enhanced Detection in Glioma Excision(EDGE) | terminated | N/A | 4 | University of OxfordOTHER | 1 | Mar 22, 2024 | clinicaltrials |
| NCT04610684 | Chemotherapy and Atezolizumab for Patients With Extensive Stage Small Cell Lung Cancer (SCLC) With Untreated, Asymptomatic Brain Metastases | terminated | Phase 2 | 3 | Jeffrey ClarkeOTHER | 1 | Mar 13, 2024 | clinicaltrials |
| NCT03705351 | Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBM | terminated | Phase 1 | 7 | Providence Health & ServicesOTHER | 1 | Mar 4, 2024 | clinicaltrials |
| NCT03403361 | Dual-Energy CT on Plan Quality, Dose-delivery Accuracy, and Simulated Outcomes of Patients Treated With Proton or Photon Therapy | terminated | N/A | 36 | Washington University School of MedicineOTHER | 1 | Mar 1, 2024 | clinicaltrials |
| NCT02905643 | Discerning Pseudoprogression vs True Tumor Growth in GBMs | terminated | — | 1 | Ascension HealthINDUSTRY | 0 | Feb 22, 2024 | clinicaltrials |
| NCT04341311 | Phase I Study of Marizomib + Panobinostat for Children With DIPG(DIPG) | terminated | Phase 1 | 4 | Dana-Farber Cancer InstituteOTHER | 1 | Feb 15, 2024 | clinicaltrials |
| NCT01345136 | Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma | terminated | Phase 2 | 4 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Feb 13, 2024 | clinicaltrials |
| NCT03275402 | 131I-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous System/Leptomeningeal Metastases | terminated | Phase 2 / Phase 3 | 52 | Y-mAbs TherapeuticsINDUSTRY | 4 | Feb 13, 2024 | clinicaltrials |
| NCT02768337 | Cambridge Brain Mets Trial 1(CamBMT1) | terminated | Phase 1 / Phase 2 | 26 | Cambridge University Hospitals NHS Foundation TrustOTHER | 1 | Jan 31, 2024 | clinicaltrials |
| NCT01894633 | Study of Whole-brain Irradiation With Chloroquine for Brain Metastases(CLQ) | terminated | Phase 2 | 73 | Instituto Nacional de Cancerologia de MexicoOTHER | 1 | Jan 24, 2024 | clinicaltrials |
| NCT00089245 | Radiolabeled MAB Therapy in Patients With Refractory, Recurrent, or Advanced CNS or Leptomeningeal Cancer | terminated | Phase 1 | 177 | Y-mAbs TherapeuticsINDUSTRY | 1 | Dec 26, 2023 | clinicaltrials |
| NCT05394558 | AsiDNA Children, Adolescents and Young Adults(AsiDNA) | terminated | Phase 1 / Phase 2 | 8 | Institut CurieOTHER | 1 | Dec 26, 2023 | clinicaltrials |
| NCT04096716 | Mapping Draining Lymph Nodes in CNS Malignancies | terminated | Phase 1 | 14 | Washington University School of MedicineOTHER | 1 | Dec 21, 2023 | clinicaltrials |
| NCT03451123 | FET-PET/MRI for Surgical Assessment of Pediatric Brain Tumors | terminated | Early Phase 1 | 1 | University of Alabama at BirminghamOTHER | 1 | Dec 19, 2023 | clinicaltrials |
| NCT03458728 | Safety, Tolerability, Efficacy and Pharmacokinetics of Copanlisib in Pediatric Patients | terminated | Phase 1 / Phase 2 | 31 | BayerINDUSTRY | 1 | Dec 4, 2023 | clinicaltrials |
| NCT02168270 | Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade Glioma | terminated | Phase 1 | 4 | University of NebraskaOTHER | 1 | Nov 24, 2023 | clinicaltrials |
| NCT02530502 | Radiation Therapy With Temozolomide and Pembrolizumab in Treating Patients With Newly Diagnosed Glioblastoma | terminated | Phase 1 | 4 | Northwestern UniversityOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT04763031 | Recurrent GBM With Maximal Neurosurgical Removal and Treatment With IORT | terminated | N/A | 1 | Parkridge Medical CenterOTHER | 1 | Nov 9, 2023 | clinicaltrials |
| NCT03939858 | Bioenergetic Profiling and Cognition in GBM Patients | terminated | — | 6 | Wake Forest University Health SciencesOTHER | 1 | Nov 8, 2023 | clinicaltrials |
| NCT02833701 | Bevacizumab and Ascorbic Acid in Patients Treating With Recurrent High Grade Glioma | terminated | Phase 1 | 9 | University of NebraskaOTHER | 1 | Oct 24, 2023 | clinicaltrials |
| NCT05414123 | A Therapy Treatment Response Trial in Patients With Leptomeningeal Metastases ((LM) Using CNSide(FORESEE) | terminated | — | 40 | Biocept, Inc.INDUSTRY | 1 | Oct 16, 2023 | clinicaltrials |
| NCT05456997 | Metabolic Myopathy in Endocrinopathy(LYDIA) | terminated | — | 1 | Barts & The London NHS TrustOTHER | 1 | Oct 16, 2023 | clinicaltrials |
| NCT04040400 | Study of Intraoperative Radiotherapy for Patients With Large Brain Metastases Treated With Neurosurgical Resection | terminated | N/A | 5 | University of LouisvilleOTHER | 1 | Oct 12, 2023 | clinicaltrials |
| NCT03190967 | T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery | terminated | Phase 1 / Phase 2 | 12 | National Cancer Institute (NCI)NIH | 1 | Oct 11, 2023 | clinicaltrials |
| NCT02659800 | Study of the Effect NT-I7 on CD4 Counts in Patients With High Grade Gliomas | terminated | Phase 1 | 12 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Oct 6, 2023 | clinicaltrials |
| NCT03593993 | A Biospecimen Collection Study in BRAF-V600E Mutated Recurrent Gliomas | terminated | — | 3 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Oct 6, 2023 | clinicaltrials |
| NCT03971734 | Determining Dose of Regadenoson Most Likely to Transiently Alter the Integrity of the Blood-Brain Barrier in Patients With High Grade Gliomas | terminated | Phase 1 | 7 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Oct 6, 2023 | clinicaltrials |
| NCT04167618 | 177Lu-DTPA-Omburtamab Radioimmunotherapy for Recurrent or Refractory Medulloblastoma | terminated | Phase 1 / Phase 2 | 2 | Y-mAbs TherapeuticsINDUSTRY | 5 | Oct 6, 2023 | clinicaltrials |
| NCT03430947 | Vemurafenib Plus Cobimetinib After Radiosurgery in Patients With BRAF-mutant Melanoma Brain Metastases(RadioCoBRIM) | terminated | Phase 2 | 20 | Technische Universität DresdenOTHER | 1 | Sep 14, 2023 | clinicaltrials |
| NCT03860207 | Study of the Safety and Efficacy of Humanized 3F8 Bispecific Antibody (Hu3F8-BsAb) in Patients With Relapsed/Refractory Neuroblastoma, Osteosarcoma and Other Solid Tumor Cancers | terminated | Phase 1 / Phase 2 | 12 | Y-mAbs TherapeuticsINDUSTRY | 1 | Sep 13, 2023 | clinicaltrials |
| NCT05116878 | Enhancing Facial Nerve Function With Omega-3 After Resection of Vestibular Schwannoma(EFFORTS) | terminated | N/A | 15 | Mayo ClinicOTHER | 1 | Sep 8, 2023 | clinicaltrials |
| NCT00659126 | Ferumoxytol- and Gadolinium-Labeled MRI in Measuring Tumors Before or After Treatment in Patients With Primary or Metastatic Brain Tumors | terminated | Phase 2 | 40 | OHSU Knight Cancer InstituteOTHER | 1 | Sep 7, 2023 | clinicaltrials |
| NCT02536183 | A Phase I Study of Lyso-thermosensitive Liposomal Doxorubicin and MR-HIFU for Pediatric Refractory Solid Tumors | terminated | Phase 1 | 2 | AeRang KimOTHER | 1 | Aug 29, 2023 | clinicaltrials |
| NCT02095353 | Comparison of Contrast Agents for MRI Perfusion Analysis in Brain Tumor Patients | terminated | — | 6 | University of NebraskaOTHER | 1 | Aug 23, 2023 | clinicaltrials |
| NCT04608812 | Convection-enhanced Delivery of OS2966 for Patients With High-grade Glioma Undergoing a Surgical Resection | terminated | Phase 1 | 7 | OncoSynergy, Inc.INDUSTRY | 1 | Aug 18, 2023 | clinicaltrials |
| NCT04644315 | A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors(ALpha-T) | terminated | Phase 2 | 1 | Hoffmann-La RocheINDUSTRY | 1 | Aug 7, 2023 | clinicaltrials |
| NCT02774291 | Anti-NY ESO-1 mTCR Peripheral Blood Lymphocytes | terminated | Early Phase 1 | 3 | Albert Einstein College of MedicineOTHER | 1 | Aug 4, 2023 | clinicaltrials |
| NCT04422639 | Preoperative SRS/SRT vs Postoperative SRS/SRT for Brain Metastases | terminated | N/A | 3 | University of ArkansasOTHER | 1 | Jul 28, 2023 | clinicaltrials |
| NCT05948137 | F-18 FDOPA PET/CT Versus I-123 MIBG Scintigraphy With SPECT/CT for the Diagnosis of Pheochromocytoma and Paraganglioma | terminated | — | 32 | Asan Medical CenterOTHER | 1 | Jul 17, 2023 | clinicaltrials |
| NCT00788125 | Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors | terminated | Phase 1 / Phase 2 | 7 | City of Hope Medical CenterOTHER | 1 | Jul 14, 2023 | clinicaltrials |
| NCT04541225 | Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors | terminated | Phase 1 | 74 | Nuvation Bio Inc.INDUSTRY | 1 | Jul 14, 2023 | clinicaltrials |
| NCT03986593 | Cryoablation of Bone Metastases From Endocrine Tumors | terminated | N/A | 17 | Instituto do Cancer do Estado de São PauloOTHER | 1 | Jul 5, 2023 | clinicaltrials |
| NCT04650204 | Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy | terminated | Phase 4 | 4 | Mayo ClinicOTHER | 1 | Jun 22, 2023 | clinicaltrials |
Data updated 23 days agoSource updated Apr 26, 2024source: clinicaltrials