Cancer Family
Nervous System Neoplasm
CI-CAN-00000038Explore in graph →
Non-malignant1,523 active trials9 approved drugs210 evidence items
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Cancer Family
CI-CAN-00000038Explore in graph →
Clinical trials
5,873 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03115398 | A Simple Walking Program to Enhance Concurrent Chemoradiotherapy Delivery | completed | N/A | 166 | Montefiore Medical CenterOTHER | 1 | Apr 13, 2026 | clinicaltrials |
| NCT03213665 | Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial) | completed | Phase 2 | 20 | National Cancer Institute (NCI)NIH | 2 | Apr 13, 2026 |
| clinicaltrials |
| NCT04988750 | Evaluate the Safety and Preliminary Efficacy of the Combination of NaviFUS System With Re-irradiation for rGBM Patients | completed | N/A | 7 | NaviFUS CorporationINDUSTRY | 1 | Apr 13, 2026 | clinicaltrials |
| NCT04446416 | Efficacy and Safety of NaviFUS System add-on Bevacizumab (BEV) in Recurrent GBM Patients | completed | N/A | 6 | NaviFUS CorporationINDUSTRY | 1 | Apr 9, 2026 | clinicaltrials |
| NCT05704933 | Pilot Study of Nivolumab w/Ipilimumab or Relatlimab in Surgically Resectable Melanoma Brain Metastases | completed | Early Phase 1 | 1 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Apr 6, 2026 | clinicaltrials |
| NCT03526250 | Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial) | completed | Phase 2 | 23 | National Cancer Institute (NCI)NIH | 2 | Apr 3, 2026 | clinicaltrials |
| NCT07497373 | A Phase I Study to Evaluate the Safety and Tolerability of JL15003 Injection in Patients With Recurrent Glioblastoma(JL15003) | completed | Phase 1 | 17 | Jecho Biopharmaceuticals Co., Ltd.INDUSTRY | 1 | Apr 3, 2026 | clinicaltrials |
| NCT00850278 | Assessment of [18F]FLT-PET Imaging for Diagnosis and Prognosis of Brain Tumors(FLT) | completed | N/A | 50 | University Hospital, CaenOTHER | 1 | Apr 2, 2026 | clinicaltrials |
| NCT06676306 | Patient and Caregiver Priorities in Neuro-oncology Care | completed | — | 33 | Mayo ClinicOTHER | 1 | Apr 1, 2026 | clinicaltrials |
| NCT06650605 | Phase 1 Open-label Study of 123I-ATT001 in Subjects With Relapsed Glioblastoma(CITADEL-123) | completed | Phase 1 | 7 | Theragnostics LtdINDUSTRY | 1 | Mar 31, 2026 | clinicaltrials |
| NCT03194971 | NovoTTF Treatment Signatures in Glioblastoma Patients at Autopsy | completed | — | 20 | Medical College of WisconsinOTHER | 1 | Mar 30, 2026 | clinicaltrials |
| NCT04471844 | Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM(EF-32) | completed | N/A | 981 | NovoCure Ltd.INDUSTRY | 11 | Mar 30, 2026 | clinicaltrials |
| NCT06826170 | Hypofractionated Radiosurgery to Treat Residual/Recurrent Non Secreting Pituitary Adenoma (HYPOADENO)(HYPOADENO) | completed | N/A | 25 | Fondazione I.R.C.C.S. Istituto Neurologico Carlo BestaOTHER | 1 | Mar 30, 2026 | clinicaltrials |
| NCT07499141 | Use of Fluorescence in Gliomas(UFGAG) | completed | — | 41 | Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di AlessandriaOTHER | 1 | Mar 30, 2026 | clinicaltrials |
| NCT04019002 | Hyperpolarized Carbon-13 (13C) Pyruvate Imaging in Patients With Glioblastoma | completed | Phase 1 | 17 | Susan ChangOTHER | 1 | Mar 27, 2026 | clinicaltrials |
| NCT04801147 | Immunotherapy With Autologous Tumor Lysate-Loaded Dendritic Cells In Patients With Newly Diagnosed Glioblastoma Multiforme(DENDR1) | completed | Phase 1 / Phase 2 | 76 | Fondazione I.R.C.C.S. Istituto Neurologico Carlo BestaOTHER | 1 | Mar 27, 2026 | clinicaltrials |
| NCT04266665 | Effect of Dexmedetomidine on Brain Homeostasis and Neurocognitive Outcome | completed | Phase 4 | 56 | Georgia TsaousiOTHER | 1 | Mar 25, 2026 | clinicaltrials |
| NCT02286167 | Glioma Modified Atkins-based Diet in Patients With Glioblastoma(GLAD) | completed | N/A | 25 | Wake Forest University Health SciencesOTHER | 1 | Mar 24, 2026 | clinicaltrials |
| NCT04074642 | OCT-angiography as a Pronostic Marker for Visual Impairment in Patients Undergoing Neurosurgery for Compressive Macroadenoma : a Prospective Study.(FIRST) | completed | N/A | 21 | Centre Hospitalier Universitaire de NiceOTHER | 1 | Mar 24, 2026 | clinicaltrials |
| NCT04545814 | Analyzing Preoperative Stereotactic Radiosurgery With Gamma Knife Icon for Brain Metastases | completed | N/A | 11 | Medical College of WisconsinOTHER | 1 | Mar 24, 2026 | clinicaltrials |
| NCT03551249 | Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption | completed | N/A | 20 | InSightecINDUSTRY | 1 | Mar 20, 2026 | clinicaltrials |
| NCT04417088 | Exablate Blood-Brain Barrier Disruption for the Treatment of rGBM in Subjects Undergoing Carboplatin Monotherapy | completed | Phase 1 / Phase 2 | 28 | InSightecINDUSTRY | 1 | Mar 20, 2026 | clinicaltrials |
| NCT01011920 | Trial for Patients With Newly Diagnosed Primary Central Nervous System (CNS) Lymphoma | completed | Phase 2 | 227 | International Extranodal Lymphoma Study Group (IELSG)OTHER | 5 | Mar 19, 2026 | clinicaltrials |
| NCT02115074 | Safety of Fluvastatin-Celebrex Association in Low-grade and High Grade Optico-chiasmatic Gliomas(FLUVABREX) | completed | Phase 1 | 20 | Centre Oscar LambretOTHER | 1 | Mar 18, 2026 | clinicaltrials |
| NCT05577416 | A Study of AB-218 in Patients With IDH1 Mutated Low Grade Glioma(AB-218-IIT-201) | completed | Early Phase 1 | 14 | Melbourne HealthOTHER | 1 | Mar 18, 2026 | clinicaltrials |
| NCT05393258 | Temporally-modulated Pulsed Radiation Therapy (TMPRT) After Prior EBRT for Recurrent IDH-mutant Gliomas | completed | N/A | 13 | Washington University School of MedicineOTHER | 1 | Mar 17, 2026 | clinicaltrials |
| NCT01165333 | Cilengitide in Combination With Irradiation in Children With Diffuse Intrinsic Pontine Glioma(CILENT) | completed | Phase 1 | 32 | Centre Oscar LambretOTHER | 1 | Mar 16, 2026 | clinicaltrials |
| NCT03475186 | Testing Ramipril to Prevent Memory Loss in People With Glioblastoma | completed | Phase 2 | 75 | Wake Forest University Health SciencesOTHER | 2 | Mar 13, 2026 | clinicaltrials |
| NCT04283669 | Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas(NF110) | completed | Phase 2 | 12 | University of Alabama at BirminghamOTHER | 1 | Mar 13, 2026 | clinicaltrials |
| NCT03257618 | Quality of Life and Neurocognitive Functioning(TEMOIN) | completed | N/A | 26 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Mar 12, 2026 | clinicaltrials |
| NCT04044937 | Fluoroethyltyrosine for Evaluation of Intracranial Neoplasms(UC-GlioFET) | completed | Phase 2 | 143 | Thomas HopeOTHER | 1 | Mar 11, 2026 | clinicaltrials |
| NCT04716699 | Systemic and Local Levels of Lidocaine During Surgery for the Removal of Glioblastoma | completed | Phase 1 | 12 | University of California, DavisOTHER | 1 | Mar 10, 2026 | clinicaltrials |
| NCT07457255 | Late Endocrine and Metabolic Consequences After Childhood Brain Tumor Treatment | completed | N/A | 12 | Institute of Oncology LjubljanaOTHER | 1 | Mar 9, 2026 | clinicaltrials |
| NCT04391595 | LY3214996 Plus Abemaciclib in Recurrent Glioblastoma Patients | completed | Early Phase 1 | 42 | Nader SanaiOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT00026312 | Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma | completed | Phase 3 | 1,449 | National Cancer Institute (NCI)NIH | 5 | Mar 5, 2026 | clinicaltrials |
| NCT03368625 | A Study of Neoadjuvant Stereotactic Radiosurgery for Large Brain Metastases(NASRS) | completed | N/A | 30 | University Health Network, TorontoOTHER | 2 | Mar 4, 2026 | clinicaltrials |
| NCT05431348 | Effect of stRess and exeRcize on the Outcome After Chemo-Radiation(ERROR) | completed | — | 42 | Maastricht Radiation OncologyOTHER | 1 | Mar 4, 2026 | clinicaltrials |
| NCT03719768 | Avelumab With Radiotherapy in Patients With Leptomeningeal Disease | completed | Phase 1 | 16 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Mar 2, 2026 | clinicaltrials |
| NCT04343573 | Proton Craniospinal Radiation Therapy vs. Partial Photon Radiation Therapy for Leptomeningeal Metastasis From Solid Tumors | completed | Phase 2 | 102 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT02669173 | Capecitabine + Bevacizumab in Patients With Recurrent Glioblastoma | completed | Phase 1 | 12 | Case Comprehensive Cancer CenterOTHER | 1 | Feb 23, 2026 | clinicaltrials |
| NCT07425678 | Comparison of Systemic Opioid (Morphine) and Pre-Incision Bilateral Scalp Nerve Block for Pain Management in Craniotomy Patients | completed | Phase 4 | 62 | Aga Khan UniversityOTHER | 1 | Feb 23, 2026 | clinicaltrials |
| NCT04268979 | Electronic Social Network Assessment Program (eSNAP) + Caregiver Navigator | completed | N/A | 296 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Feb 20, 2026 | clinicaltrials |
| NCT05984667 | C-SMART: Cognitive Strategies, Mindfulness, and Rehabilitation Therapy for Patients With Primary Brain Tumors(C-SMART) | completed | — | 32 | Virginia Commonwealth UniversityOTHER | 1 | Feb 20, 2026 | clinicaltrials |
| NCT03429803 | DAY101 In Gliomas and Other Tumors | completed | Phase 1 | 44 | Karen D. Wright, MDOTHER | 1 | Feb 19, 2026 | clinicaltrials |
| NCT05938387 | Safety and Tolerability of CVGBM in Adults With Newly Diagnosed MGMT-Unmethylated Glioblastoma or Astrocytoma | completed | Phase 1 | 37 | CureVacINDUSTRY | 3 | Feb 18, 2026 | clinicaltrials |
| NCT07416838 | Quality of Life and Cognitive Functioning in Patients With Glial Tumors | completed | N/A | 90 | Institute of Oncology LjubljanaOTHER | 1 | Feb 18, 2026 | clinicaltrials |
| NCT02073994 | Study of Orally Administered AG-120 in Subjects With Advanced Solid Tumors, Including Glioma, With an IDH1 Mutation | completed | Phase 1 | 174 | Institut de Recherches Internationales ServierOTHER | 2 | Feb 17, 2026 | clinicaltrials |
| NCT02481154 | Study of Orally Administered AG-881 in Patients With Advanced Solid Tumors, Including Gliomas, With an IDH1 and/or IDH2 Mutation | completed | Phase 1 | 95 | Institut de Recherches Internationales ServierOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT03343197 | Study of AG-120 and AG-881 in Subjects With Low Grade Glioma | completed | Phase 1 | 49 | Institut de Recherches Internationales ServierOTHER | 1 | Feb 17, 2026 | clinicaltrials |
Data updated 23 days agoSource updated Apr 13, 2026source: clinicaltrials