Subtype
Nasopharyngeal Carcinoma
CI-CAN-00008100NPCExplore in graph →
246 active trials1 approved drugs
- NCIt
- C3871
- OncoTree
- NPC
- UMLS CUI
- C2931822
- MeSH
- D000077274
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Subtype
CI-CAN-00008100NPCExplore in graph →
Clinical trials
702 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (35)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04929080 | The Safety and Efficacy of Multiple-dose of JS004 in Subject With HNC | completed | Phase 1 / Phase 2 | 149 | Shanghai Junshi Bioscience Co., Ltd.OTHER | 1 | Aug 1, 2023 | clinicaltrials |
| NCT00834093 | A Phase II Study of Epstein-Barr Virus-Specific Immunotherapy for Nasopharyngeal Carcinoma | completed | Phase 2 | 18 | Dana-Farber Cancer InstituteOTHER | 1 | Jun 28, 2023 | clinicaltrials |
| NCT02578641 | A Phase III Trial Evaluating Chemotherapy and Immunotherapy for Advanced Nasopharyngeal Carcinoma (NPC) Patients(VANCE) | completed | Phase 3 | 330 | Tessa TherapeuticsINDUSTRY | 5 | Jun 28, 2023 | clinicaltrials |
| NCT03429868 | PET and MRI in Prognosis Prediction of NPC | completed | N/A | 180 | Chang Gung Memorial HospitalOTHER | 1 | May 10, 2023 | clinicaltrials |
| NCT02940925 | TPC vs PF as Induction Chemotherapy Combined With CCRT for Stage IVa-b Nasopharyngeal Carcinoma | completed | Phase 3 | 241 | Sun Yat-sen UniversityOTHER | 1 | Apr 12, 2023 | clinicaltrials |
| NCT03849469 | A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors(DUET-4) | completed | Phase 1 | 78 | Xencor, Inc.INDUSTRY | 1 | Mar 30, 2023 | clinicaltrials |
| NCT04945421 | IBI310 in Combination With Siltilimab in Subjects With Anti-PD-1/PD-L1 Resistance R/M NPC | completed | Phase 1 | 30 | Innovent Biologics (Suzhou) Co. Ltd.INDUSTRY | 1 | Feb 23, 2023 | clinicaltrials |
| NCT04350190 | Apatinib Combined With PD-1 in the Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma | completed | Phase 2 | 25 | Wei JiangOTHER | 1 | Jan 13, 2023 | clinicaltrials |
| NCT03517488 | A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors(DUET-2) | completed | Phase 1 | 150 | Xencor, Inc.INDUSTRY | 1 | Dec 1, 2022 | clinicaltrials |
| NCT04636632 | Fosaprepitant for the Prevention of Nausea and Emesis During Concurrent Chemoradiotherapy for Nasopharyngeal Carcinoma | completed | Phase 1 | 100 | Sun Yat-sen UniversityOTHER | 1 | Nov 7, 2022 | clinicaltrials |
| NCT02460419 | Maintenance Capecitabine Plus Best Supportive Care Versus Best Supportive Care for Metastatic Nasopharyngeal Carcinoma | completed | Phase 3 | 104 | Sun Yat-sen UniversityOTHER | 1 | Oct 28, 2022 | clinicaltrials |
| NCT00274937 | Radiation Therapy, Amifostine, and Chemotherapy in Treating Young Patients With Newly Diagnosed Nasopharyngeal Cancer | completed | Phase 3 | 111 | Children's Oncology GroupNETWORK | 3 | Oct 25, 2022 | clinicaltrials |
| NCT00188253 | Positron Emission Tomography Scanning and Epstein-Barr Virus DNA Levels in the Staging and Follow-up of Nasopharyngeal Carcinoma. | completed | — | 30 | University Health Network, TorontoOTHER | 1 | Oct 18, 2022 | clinicaltrials |
| NCT03448341 | Dysphagia Assessment After Swallowing Sparing RadioTherapy(DASRT) | completed | — | 74 | Azienda Ospedaliero, Universitaria PisanaOTHER | 1 | Sep 15, 2022 | clinicaltrials |
| NCT00470496 | Photodynamic Therapy Using HPPH in Treating Patients Undergoing Surgery for Primary or Recurrent Head and Neck Cancer | completed | Phase 1 | 15 | Roswell Park Cancer InstituteOTHER | 1 | Jul 25, 2022 | clinicaltrials |
| NCT03121716 | A Study to Evaluate the Safety and Efficacy of SHR-1210, Gemcitabine and Cis-platinum by R/M NPC Subjects | completed | Phase 1 | 23 | Jiangsu HengRui Medicine Co., Ltd.INDUSTRY | 1 | Jul 12, 2022 | clinicaltrials |
| NCT04834206 | Nedaplatin in Treatment for Nasopharyngeal Carcinoma | completed | Phase 2 | 32 | Affiliated Cancer Hospital & Institute of Guangzhou Medical UniversityOTHER | 1 | May 10, 2022 | clinicaltrials |
| NCT04508816 | Anti-EGFR Therapy Plus IMRT Concurrent Chemoradiotherapy in Locally Advanced NPC Resistant to Induction Chemotherapy | completed | Phase 2 | 45 | Fudan UniversityOTHER | 1 | Apr 4, 2022 | clinicaltrials |
| NCT02562599 | Chemoradiotherapy for Patients With Locally Advanced Nasopharyngeal Carcinoma Using Raltitrexed-Cisplatin | completed | Phase 2 | 60 | Hubei Cancer HospitalOTHER | 1 | Feb 22, 2022 | clinicaltrials |
| NCT02237924 | Endostar Combined With Intensity-modulated Radiotherapy Compare With Chemoradiation for Nasopharyngeal Carcinoma | completed | Phase 2 | 120 | First Affiliated Hospital of Guangxi Medical UniversityOTHER | 1 | Feb 14, 2022 | clinicaltrials |
| NCT02605967 | Safety and Efficacy Study of PDR001 in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma | completed | Phase 2 | 122 | Novartis PharmaceuticalsINDUSTRY | 7 | Feb 10, 2022 | clinicaltrials |
| NCT02642107 | Individualized Elective Neck Irradiation Based on MRI in NPC Patients(NPC-CTVn) | completed | Phase 3 | 446 | Sun Yat-sen UniversityOTHER | 1 | Nov 5, 2021 | clinicaltrials |
| NCT00592501 | Proton Radiotherapy With Chemotherapy for Nasopharyngeal Carcinoma | completed | Phase 2 | 25 | Massachusetts General HospitalOTHER | 1 | Oct 26, 2021 | clinicaltrials |
| NCT03096808 | Adaptive Radiotherapy for Head and Neck Cancer | completed | Phase 2 | 64 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Oct 26, 2021 | clinicaltrials |
| NCT03352778 | IMRT vs 2DRT for NPC Patients | completed | — | 60 | Chinese University of Hong KongOTHER | 1 | Oct 22, 2021 | clinicaltrials |
| NCT04394065 | uEXPLORER Total-body PET/CT in Nasopharyngeal Carcinoma | completed | — | 56 | Sun Yat-sen UniversityOTHER | 1 | Sep 17, 2021 | clinicaltrials |
| NCT05020067 | Impact on Xerostomia for Nasopharyngeal Carcinoma Patients Treated With or Without Superficial Parotid Lobe-sparing Intensity-modulated Radiotherapy | completed | Phase 2 | 90 | Sun Yat-sen UniversityOTHER | 1 | Aug 25, 2021 | clinicaltrials |
| NCT03379610 | A Prospective Study of Molecular Detection of Salvageable Early Recurrent Nasopharyngeal Carcinoma After Radiotherapy | completed | — | 426 | The University of Hong KongOTHER | 0 | Apr 30, 2021 | clinicaltrials |
| NCT00896181 | Phase 2 Sequential and Concurrent Chemoradiation for Advanced Nasopharyngeal Carcinoma (NPC) | completed | Phase 2 | 26 | Stanford UniversityOTHER | 1 | Apr 6, 2021 | clinicaltrials |
| NCT03668366 | S-1 Combined With IMRT Concurrent Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma | completed | Phase 2 | 133 | Fudan UniversityOTHER | 1 | Feb 11, 2021 | clinicaltrials |
| NCT03601390 | Combining PET/CT and EBV DNA to Evaluate the Hazard of Progression in the Follow-up of Locally Advanced NPC | completed | — | 387 | Sun Yat-sen UniversityOTHER | 1 | Dec 19, 2020 | clinicaltrials |
| NCT02586532 | Evaluation of the Sensitivity of Endoscopy to Detect Nasopharyngeal Carcinoma (NPC) in an Epstein-Barr Virus (EBV)-Based NPC Screening Project in China | completed | — | 828 | National Cancer Institute (NCI)NIH | 1 | Dec 11, 2020 | clinicaltrials |
| NCT04387266 | To Evaluate the Efficacy and Feasibility of Modified Reduce-volume Target IMRT in the Treatment of Patients With Non-metastatic NPC | completed | — | 471 | Fujian Cancer HospitalOTHER_GOV | 1 | Oct 9, 2020 | clinicaltrials |
| NCT03989297 | PD-L1 and BRAF Expression in Nasopharyngeal Carcinoma | completed | — | 104 | Kiang Wu HospitalOTHER | 1 | Sep 2, 2020 | clinicaltrials |
| NCT02575547 | Effect of Chemoradiotherapy on Nutritional Status in Advanced NPC Patients | completed | — | 186 | Zhao ChongOTHER | 1 | Jul 30, 2020 | clinicaltrials |
| NCT01187238 | The Value of Concurrent Chemoradiotherapy for Stage II Nasopharyngeal Carcinoma | completed | Phase 2 | 84 | Chinese Academy of Medical SciencesOTHER | 1 | Jul 16, 2020 | clinicaltrials |
| NCT00341146 | Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s) | completed | — | 6,490 | National Cancer Institute (NCI)NIH | 1 | Jun 16, 2020 | clinicaltrials |
| NCT03670342 | Pilot Study of Somatostatin Receptor Imaging in Nasopharyngeal Cancer | completed | — | 20 | National Cancer Centre, SingaporeOTHER | 1 | Apr 30, 2020 | clinicaltrials |
| NCT01344356 | Stereotactic Body Radiotherapy for Head and Neck Tumors | completed | Phase 4 | 19 | Mercy ResearchOTHER | 1 | Apr 10, 2020 | clinicaltrials |
| NCT01254617 | Lenalidomide and Cetuximab in Treating Patients With Advanced Colorectal Cancer or Head and Neck Cancer(ADCC) | completed | Phase 1 | 24 | National Cancer Institute (NCI)NIH | 1 | Mar 13, 2020 | clinicaltrials |
| NCT01447056 | Most Closely HLA-Matched CTLs for Relapsed Epstein Barr Virus(EBV)-Associated Diseases(MALTED) | completed | Phase 1 | 37 | Baylor College of MedicineOTHER | 1 | Feb 7, 2020 | clinicaltrials |
| NCT03389295 | Reduced Target Delineation and Radiation Doses Chemoradiotherapy for Patients With Locoregionally Advanced Nasopharyngeal Carcinoma | completed | Phase 2 | 118 | Xiayun He, MDOTHER | 1 | Dec 16, 2019 | clinicaltrials |
| NCT01806675 | 18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy | completed | Phase 1 / Phase 2 | 25 | Sanjiv Sam GambhirOTHER | 1 | Oct 3, 2019 | clinicaltrials |
| NCT02794077 | Cyclophosphamide for Nasopharyngeal Carcinoma | completed | Phase 2 | 56 | The University of Hong KongOTHER | 0 | Oct 2, 2019 | clinicaltrials |
| NCT04108338 | Prospective Comparisons of Clinical Trial and Real-world Outcomes in Nasopharyngeal Carcinoma | completed | — | 5,448 | Sun Yat-sen UniversityOTHER | 1 | Oct 1, 2019 | clinicaltrials |
| NCT04094545 | Intestinal Flora Sequencing for Nasopharyngeal Carcinoma | completed | — | 568 | The Third Xiangya Hospital of Central South UniversityOTHER | 1 | Sep 19, 2019 | clinicaltrials |
| NCT02339558 | Nivolumab in Treating Patients With Recurrent and/or Metastatic Nasopharyngeal Cancer | completed | Phase 2 | 45 | National Cancer Institute (NCI)NIH | 3 | Sep 13, 2019 | clinicaltrials |
| NCT00379262 | Therapeutic Gain by Induction-concurrent Chemoradiotherapy and/or Accelerated Fractionation for Nasopharyngeal Carcinoma | completed | Phase 3 | 803 | Hong Kong Nasopharyngeal Cancer Study Group LimitedOTHER | 1 | Aug 7, 2019 | clinicaltrials |
| NCT01309633 | Study Evaluating Two Loading Regimens of Sunitinib or Bevacizumab Alternating With Cisplatin and Gemcitabine as Induction Therapy for Locally Advanced Nasopharyngeal Carcinoma (NPC) | completed | Phase 2 | 80 | National University Hospital, SingaporeOTHER | 1 | Jul 22, 2019 | clinicaltrials |
Data updated 23 days agoSource updated Aug 1, 2023source: clinicaltrials