Myxoid Glioneuronal Tumor — Variants & evidence

Myxoid Glioneuronal Tumor — Variants & evidence · CancerIndex

Variants & evidence

Curated clinical evidence by variant and therapy

2 evidence items mapped to this entity or its descendants, grouped by molecular profile, then therapy. 50 items per page.

civicCuratedShowing 1–2 of 2 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
PDGFRA K3852
(diagnostic)	Diagnostic	C	Supports Positive	3	submitted	EID10669 Mutations at codon K385 are specific to glial and glioneuronal tumors. In addition, tumors with these mutations do not typically have other pathogenic mutations in other typical brain-cancer-associate… (full text at CIViC) PMID 30006677 · Solomon et al., 2018 · Open in CIViC	civic
〃	Diagnostic	C	Supports Positive	3	submitted	EID10670 PDGFRA K385L (6) or K385I (2) mutations were identified as the sole somatic pathogenic alteration in 8 patients with low-grade glioneuronal tumors; furthering defining "Myxoid glioneuronal tumor, PDGF… (full text at CIViC) PMID 31609499 · Lucas et al., 2020 · Open in CIViC	civic

Data updated 23 hours agoSource updated unknownsource: civic (CC0)

Evidence levels, directions and ratings are those assigned by CIViC curators. "Submitted" items have not completed curation review. This is not treatment guidance.