Hematologic Malignancy
Myeloid Leukemia
CI-CAN-00001251Explore in graph →
Hematologic862 active trials22 approved drugs599 evidence items
Loading cancer entity…
Loading cancer entity…
Hematologic Malignancy
CI-CAN-00001251Explore in graph →
Clinical trials
3,530 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (619)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01119066 | HLA-Compatible Related or Unrelated Donors With CD34+ Enriched, T-cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients With Hematologic Malignancies | completed | Phase 2 | 422 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Aug 5, 2022 | clinicaltrials |
| NCT01168219 | Busulfan, Fludarabine Phosphate, and Anti-Thymocyte Globulin Followed By Donor Stem Cell Transplant and Azacitidine in Treating Patients With High-Risk Myelodysplastic Syndrome and Older Patients With Acute Myeloid Leukemia | completed | Phase 2 | 68 | National Cancer Institute (NCI) |
| 1 |
| Aug 4, 2022 |
| clinicaltrials |
| NCT01253070 | Sorafenib Tosylate and Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia | completed | Phase 2 | 54 | National Cancer Institute (NCI)NIH | 1 | Aug 4, 2022 | clinicaltrials |
| NCT03723681 | Study of Quizartinib in Combination With Standard Therapies in Chinese Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) | completed | Phase 1 | 7 | Daiichi Sankyo Co., Ltd.INDUSTRY | 1 | Jul 29, 2022 | clinicaltrials |
| NCT04452604 | Multicentric Registry of Patients With Acute Leukemia Infected by COVID-19(COVLA) | completed | — | 79 | French Innovative Leukemia OrganisationOTHER | 1 | Jul 27, 2022 | clinicaltrials |
| NCT03035422 | Sequential Conditioning in Haploidentical Transplantation for Refractory Acute Myeloid Leukemia(SET-HAPLO) | completed | N/A | 24 | Association for Training, Education, and Research in Hematology, Immunology, and TransplantationOTHER | 1 | Jul 25, 2022 | clinicaltrials |
| NCT01834248 | DEC-205/NY-ESO-1 Fusion Protein CDX-1401and Decitabine in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia | completed | Phase 1 | 9 | Roswell Park Cancer InstituteOTHER | 1 | Jul 22, 2022 | clinicaltrials |
| NCT02546674 | Study Assessing Deep Molecular Response in Adult Patients With CML in Chronic Phase Treated With Nilotinib Firstline.(NILOdeepR) | completed | Phase 4 | 171 | Novartis PharmaceuticalsINDUSTRY | 1 | Jul 22, 2022 | clinicaltrials |
| NCT01005277 | Study of Biomarkers in DNA Samples From Patients With Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia | completed | — | 2,000 | Children's Oncology GroupNETWORK | 1 | Jul 14, 2022 | clinicaltrials |
| NCT05456048 | Influence of Molecular Abnormalities on Response of VAH vs. VEN+HMA in RR-AML | completed | — | 231 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Jul 13, 2022 | clinicaltrials |
| NCT05169307 | CPX-351 Real-World Effectiveness and Safety Study | completed | — | 147 | Jazz PharmaceuticalsINDUSTRY | 1 | Jul 12, 2022 | clinicaltrials |
| NCT02109744 | Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients(AML) | completed | Phase 1 / Phase 2 | 27 | University of RochesterOTHER | 1 | Jul 5, 2022 | clinicaltrials |
| NCT01093573 | Midostaurin and Azacitidine in Treating Elderly Patients With Acute Myelogenous Leukemia | completed | Phase 1 / Phase 2 | 34 | Brenda Cooper, MDOTHER | 1 | Jun 30, 2022 | clinicaltrials |
| NCT01244750 | Studying First Line Treatment of Chronic Myeloid Leukemia (CML) in a Real-world Setting(SIMPLICITY) | completed | — | 1,494 | Bristol-Myers SquibbINDUSTRY | 8 | Jun 30, 2022 | clinicaltrials |
| NCT02551718 | High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia | completed | N/A | 34 | University of WashingtonOTHER | 1 | Jun 30, 2022 | clinicaltrials |
| NCT03848754 | Pracinostat and Gemtuzumab Ozogamicin (PraGO) in Patients With Relapsed/Refractory Acute Myeloid Leukemia | completed | Phase 1 | 14 | Medical College of WisconsinOTHER | 1 | Jun 30, 2022 | clinicaltrials |
| NCT03509896 | Study of Chinese Newly Diagnosed Participants With Philadelphia Chromosome-Positive (Ph+) Chronic Myeloid Leukemia in Chronic Phase (CML-CP) | completed | — | 463 | Bristol-Myers SquibbINDUSTRY | 1 | Jun 27, 2022 | clinicaltrials |
| NCT01303796 | A Study of Oral Sapacitabine in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia(SEAMLESS) | completed | Phase 3 | 482 | Cyclacel Pharmaceuticals, Inc.INDUSTRY | 12 | Jun 22, 2022 | clinicaltrials |
| NCT04089839 | A Study of Dasatinib Management Among CP-CML (Chronic Phase, Chronic Myeloid Leukemia) Participants Initiating Dasatinib in a Real Life Setting | completed | — | 177 | Bristol-Myers SquibbINDUSTRY | 1 | Jun 21, 2022 | clinicaltrials |
| NCT01667133 | A Study of Ponatinib in Japanese Participants With Chronic Myeloid Leukemia (CML) and Ph+ Acute Lymphoblastic Leukemia (ALL) | completed | Phase 1 / Phase 2 | 35 | Ariad PharmaceuticalsINDUSTRY | 1 | Jun 13, 2022 | clinicaltrials |
| NCT02842320 | Targeting Leukemic Stem Cell Expressing the IL-1RAP Protein in Chronic Myelogenous Leukemia (CML)(CAR-LMC) | completed | N/A | 53 | Centre Hospitalier Universitaire de BesanconOTHER | 1 | Jun 1, 2022 | clinicaltrials |
| NCT04788420 | Influence of Co-existing Mutations on Sorafenib Maintenance Therapy After Allo-HSCT for Patients With FLT3-ITD AML | completed | — | 456 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Jun 1, 2022 | clinicaltrials |
| NCT03483324 | Trial of AB-110 in Adults With Hematologic Malignancies Undergoing Cord Blood Transplantation | completed | Phase 1 | 10 | Angiocrine BioscienceINDUSTRY | 1 | May 31, 2022 | clinicaltrials |
| NCT05387330 | Dynamic Changes in the Levels of sCD62L and SPARC in Chronic Myeloid Leukemia Patients During Imatinib Treatment | completed | — | 35 | Tanta UniversityOTHER | 1 | May 24, 2022 | clinicaltrials |
| NCT03128411 | Study of Bosutinib in Japanese Adult Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia | completed | Phase 2 | 64 | PfizerINDUSTRY | 1 | May 19, 2022 | clinicaltrials |
| NCT02979366 | Phase I Study of S64315 Administred Intravenously in Patients With Acute Myeloid Leukaemia or Myelodysplastic Syndrome | completed | Phase 1 | 38 | Institut de Recherches Internationales ServierOTHER | 4 | May 18, 2022 | clinicaltrials |
| NCT03429387 | PET/CT and Bacterial/Fungal PCR in High Risk Febrile Neutropenia(PIPPIN) | completed | N/A | 147 | Peter MacCallum Cancer Centre, AustraliaOTHER | 1 | May 17, 2022 | clinicaltrials |
| NCT02200978 | A Study for Improving the Outcome of Childhood Acute Promyeloid Leukemia | completed | Phase 4 | 176 | South China Children's Leukemia GroupOTHER | 1 | May 10, 2022 | clinicaltrials |
| NCT00450450 | Donor Bone Marrow Transplant With or Without G-CSF in Treating Young Patients With Hematologic Cancer or Other Diseases | completed | Phase 3 | 27 | Children's Oncology GroupNETWORK | 1 | Apr 28, 2022 | clinicaltrials |
| NCT03449745 | Immune Checkpoint Receptors in AML-Leukemic Initiating Cells(ICAML-LIC) | completed | — | 199 | University Hospital, BordeauxOTHER | 1 | Apr 20, 2022 | clinicaltrials |
| NCT03563560 | A Study of DSP-2033 (Alvocidib) in Patients With Acute Myeloid Leukemia(AML) | completed | Phase 1 | 10 | Sumitomo Pharma Co., Ltd.INDUSTRY | 1 | Apr 12, 2022 | clinicaltrials |
| NCT03678454 | Iclusig® (Ponatinib) in Clinical Practice for the Treatment of Chronic Myeloid Leukemia or Ph+ Acute Lymphoblastic Leukemia in Belgium | completed | — | 80 | Incyte Biosciences BeneluxINDUSTRY | 1 | Apr 12, 2022 | clinicaltrials |
| NCT03787498 | A Study of PLX2853 in Relapsed or Refractory Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome | completed | Phase 1 | 22 | Opna Bio LLCINDUSTRY | 1 | Apr 12, 2022 | clinicaltrials |
| NCT02566395 | Stem Cell Transplantation From HLA Partially-Matched Related Donors for Patients With Hematologic Malignancies | completed | Phase 3 | 10 | Northwell HealthOTHER | 1 | Apr 7, 2022 | clinicaltrials |
| NCT00900809 | QUILT-3.018: Neukoplast™ (NK-92) for the Treatment of Refractory or Relapsed Acute Myeloid Leukemia | completed | Phase 1 | 7 | ImmunityBio, Inc.INDUSTRY | 1 | Apr 5, 2022 | clinicaltrials |
| NCT04014764 | Collect and Assess Tissue Samples From Subjects With Hematologic Malignancy((ANSWer)) | completed | — | 119 | Notable LabsINDUSTRY | 3 | Apr 5, 2022 | clinicaltrials |
| NCT01411267 | AC220 for Children With Relapsed/Refractory ALL or AML | completed | Phase 1 | 24 | Therapeutic Advances in Childhood Leukemia ConsortiumOTHER | 1 | Apr 4, 2022 | clinicaltrials |
| NCT02353728 | Stem Cell Monitoring for CML Patients Undergoing Nilotinib Therapy | completed | Phase 2 | 16 | Weill Medical College of Cornell UniversityOTHER | 1 | Mar 25, 2022 | clinicaltrials |
| NCT00531232 | A Dose Confirmation Study of Oral Clofarabine for Adult Patients Previously Treated for Myelodysplastic Syndromes (MDS) | completed | Phase 2 | 38 | Genzyme, a Sanofi CompanyINDUSTRY | 1 | Mar 24, 2022 | clinicaltrials |
| NCT01683123 | Study With Intravenous Busulfan And Fludarabine Myeloablative Conditioning Regimen For HLA Identical Sibling Donor HSCT(BUFLU) | completed | — | 143 | Grupo Espanol de trasplantes hematopoyeticos y terapia celularOTHER | 0 | Mar 17, 2022 | clinicaltrials |
| NCT03985007 | CDIAG Regimen in the Treatment of Relapsed or Refractory Acute Myeloid Leukemia | completed | Phase 2 | 40 | The First Affiliated Hospital of Soochow UniversityOTHER | 1 | Mar 17, 2022 | clinicaltrials |
| NCT01433965 | Study of Lenalidomide in Patients With Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome | completed | Phase 1 | 16 | University of California, DavisOTHER | 1 | Mar 10, 2022 | clinicaltrials |
| NCT03719183 | Comparison of Diagnostic Yield Among M-FISH, FISH Probe Panel and Conventional Cytogenetic Analysis in AML | completed | — | 120 | Assiut UniversityOTHER | 1 | Mar 9, 2022 | clinicaltrials |
| NCT02730312 | PH 1 Study to Evaluate Safety and Tolerability of XmAb14045 in Patients With CD123-expressing Hematologic Malignancies | completed | Phase 1 | 120 | Xencor, Inc.INDUSTRY | 1 | Mar 8, 2022 | clinicaltrials |
| NCT03012672 | Higher or Lower Dose Cladribine, Cytarabine, and Mitoxantrone in Treating Medically Less Fit Patients With Newly Diagnosed Acute Myeloid Leukemia or Myeloid Neoplasm | completed | Phase 2 | 50 | University of WashingtonOTHER | 1 | Mar 8, 2022 | clinicaltrials |
| NCT04327037 | Safety of Expanded Haploidentical Natural Killer Cells for Leukemia | completed | Phase 1 | 10 | Belarusian Research Center for Pediatric Oncology, Hematology and ImmunologyOTHER | 1 | Mar 2, 2022 | clinicaltrials |
| NCT01810705 | GRASPA Treatment for Patients With Acute Myeloblastic Leukemia(ENFORCE) | completed | Phase 2 | 123 | ERYtech PharmaINDUSTRY | 1 | Feb 21, 2022 | clinicaltrials |
| NCT00352365 | Lenalidomide in Treating Older Patients With Acute Myeloid Leukemia | completed | Phase 2 | 41 | National Cancer Institute (NCI)NIH | 1 | Feb 11, 2022 | clinicaltrials |
Data updated 24 days agoSource updated Aug 5, 2022source: clinicaltrials