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Variants & evidence
3 evidence items mapped to this entity or its descendants, grouped by molecular profile, then therapy. 50 items per page.
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| MAML2 Fusion3 | ||||||||
| (diagnostic) | Salivary Gland Mucoepidermoid Carcinoma | Diagnostic | B | Supports Positive | 4 | accepted | EID11591In this 2010 study, the authors included 55 salivary gland mucoepidermoid carcinomas (MEC) and a control group of 36 potential MEC mimics, including Warthin tumors, oncocytomas, squamous cell carcinom… (full text at CIViC) PMID 20588178 · Seethala et al., 2010 · Open in CIViC | civic |
| 〃 | Salivary Gland Mucoepidermoid Carcinoma | Diagnostic | B | Supports Positive | 3 | accepted | EID11592In this 2013 study, the authors investigated 95 salivary gland mucoepidermoid carcinomas (MEC) using FFPE material. RT-PCR and FISH were utilized to detect CRTC1::MAML2 and CRTC3::MAML2 fusions, as we… (full text at CIViC) PMID 23035786 · Noda et al., 2013 · Open in CIViC | civic |
| 〃 | Salivary Gland Mucoepidermoid Carcinoma | Diagnostic | B | Supports Positive | 3 | accepted | EID11593In this 2009 study, the authors investigated 101 mucoepidermoid carcinomas (MECs) and 89 non-MEC salivary gland tumors using RT-PCR to detect CRTC1::MAML2, CRTC2::MAML2, and CRTC3::MAML2 fusions. The … (full text at CIViC) PMID 19749740 · Nakayama et al., 2009 · Open in CIViC | civic |
Data updated 19 minutes agoSource updated unknownsource: civic (CC0)
Evidence levels, directions and ratings are those assigned by CIViC curators. "Submitted" items have not completed curation review. This is not treatment guidance.