Cancer Family
Malignant Skin Neoplasm
CI-CAN-00000250Explore in graph →
320 active trials14 approved drugs64 evidence items
- NCIt
- C2920
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Cancer Family
CI-CAN-00000250Explore in graph →
Genomics
19 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
121 cases with simple somatic mutation data · 121 cases total · 2026-01-13 · mapped to Cutaneous Melanoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TTN |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 98 |
| 121 |
| 81% |
| cbioportal |
| 2 | MUC16 | Ssm | 88 | 121 | 72.7% | cbioportal |
| 3 | BRAF | Ssm | 76 | 121 | 62.8% | cbioportal |
| 4 | DNAH5 | Ssm | 61 | 121 | 50.4% | cbioportal |
| 6 | PCLO | Ssm | 56 | 121 | 46.3% | cbioportal |
| 5 | LRP1B | Ssm | 56 | 121 | 46.3% | cbioportal |
| 7 | CSMD1 | Ssm | 48 | 121 | 39.7% | cbioportal |
| 9 | PKHD1L1 | Ssm | 47 | 121 | 38.8% | cbioportal |
| 8 | APOB | Ssm | 47 | 121 | 38.8% | cbioportal |
| 12 | MUC17 | Ssm | 46 | 121 | 38% | cbioportal |
| 10 | ANK3 | Ssm | 46 | 121 | 38% | cbioportal |
| 11 | DNAH7 | Ssm | 46 | 121 | 38% | cbioportal |
| 13 | USH2A | Ssm | 44 | 121 | 36.4% | cbioportal |
| 14 | ADGRV1 | Ssm | 43 | 121 | 35.5% | cbioportal |
| 15 | CSMD2 | Ssm | 43 | 121 | 35.5% | cbioportal |
| 16 | DNAH8 | Ssm | 42 | 121 | 34.7% | cbioportal |
| 17 | FAT4 | Ssm | 41 | 121 | 33.9% | cbioportal |
| 18 | ZFHX4 | Ssm | 40 | 121 | 33.1% | cbioportal |
| 19 | HYDIN | Ssm | 39 | 121 | 32.2% | cbioportal |
| 20 | MGAM | Ssm | 38 | 121 | 31.4% | cbioportal |
| 21 | MXRA5 | Ssm | 38 | 121 | 31.4% | cbioportal |
| 23 | UNC13C | Ssm | 37 | 121 | 30.6% | cbioportal |
| 22 | PREX2 | Ssm | 37 | 121 | 30.6% | cbioportal |
| 27 | SPHKAP | Ssm | 36 | 121 | 29.8% | cbioportal |
| 26 | RP1 | Ssm | 36 | 121 | 29.8% | cbioportal |
| 24 | FAT3 | Ssm | 36 | 121 | 29.8% | cbioportal |
| 25 | MYH4 | Ssm | 36 | 121 | 29.8% | cbioportal |
| 31 | TPTE | Ssm | 35 | 121 | 28.9% | cbioportal |
| 28 | CSMD3 | Ssm | 35 | 121 | 28.9% | cbioportal |
| 29 | PAPPA2 | Ssm | 35 | 121 | 28.9% | cbioportal |
Data updated 22 days agoSource updated 2026-01-13