Cancer Family
Malignant Respiratory System Neoplasm
CI-CAN-00000249Explore in graph →
2,650 active trials51 approved drugs619 evidence items
- NCIt
- C4571
Loading cancer entity…
Loading cancer entity…
Cancer Family
CI-CAN-00000249Explore in graph →
Clinical trials
11,130 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (1,492)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05107674 | A Study of NX-1607 in Adults With Advanced Malignancies | recruiting | Phase 1 | 345 | Nurix Therapeutics, Inc.INDUSTRY | 2 | Sep 9, 2025 | clinicaltrials |
| NCT06512207 | A Study on the Efficacy of Androgen Deprivation Therapy Combined With Anti-PD-1 Therapy in Advanced Lung Cancer | recruiting | N/A | 80 | Jinzhou Medical UniversityOTHER | 1 | Sep 9, 2025 | clinicaltrials |
| NCT06682793 |
| A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression(DENALI-1) |
| recruiting |
| Phase 1 / Phase 2 |
| 240 |
| A2 Biotherapeutics Inc.INDUSTRY |
| 1 |
| Sep 9, 2025 |
| clinicaltrials |
| NCT06262321 | Thoracic Radiotherapy for Patients With Metastatic (Stage IV) Non-Small Cell Lung Cancer at High Risk of Symptomatic Progression Within the Thorax(DRO2301) | recruiting | Phase 2 | 48 | University of RochesterOTHER | 1 | Sep 8, 2025 | clinicaltrials |
| NCT06548711 | Effect of Transcutaneous Acupoint Electrical Stimulation (TAES) on Postoperative Cough in Lung Cancer | recruiting | N/A | 84 | Kong FanmingOTHER | 1 | Sep 8, 2025 | clinicaltrials |
| NCT06868485 | A Study to Assess the Efficacy of WSD0922-FU in Patients With C797S+ Advanced Non-small Cell Lung Cancer | recruiting | Phase 2 | 40 | Wayshine Biopharm, Inc.INDUSTRY | 3 | Sep 8, 2025 | clinicaltrials |
| NCT07150663 | Nanocrystalline Megestrol Acetate in Concurrent Chemoradiotherapy for Locally Advanced Non-Small Cell Lung Cancer | recruiting | Phase 3 | 134 | Changchun GeneScience Pharmaceutical Co., Ltd.INDUSTRY | 1 | Sep 8, 2025 | clinicaltrials |
| NCT05903430 | A Feasibility Study of MRI Guided Stereotactic Ablative Radiotherapy (MIDSECTION)(MIDSECTION) | recruiting | — | 60 | The Christie NHS Foundation TrustOTHER | 1 | Sep 5, 2025 | clinicaltrials |
| NCT06127303 | Toripalimab Combined With Cryoablation for First-line Oligo-progression in Driver-negative Advanced NSCLC | recruiting | Phase 2 | 54 | Shanghai Chest HospitalOTHER | 1 | Sep 5, 2025 | clinicaltrials |
| NCT05874401 | Trilaciclib vs Placebo in Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC) Receiving Topotecan | recruiting | Phase 4 | 302 | Pharmacosmos A/SINDUSTRY | 1 | Sep 4, 2025 | clinicaltrials |
| NCT04300062 | Tumor Rebiopsy During Progression Under Immunotherapy for Patients With Lung Cancer(REBIMMUNE) | recruiting | N/A | 50 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Sep 3, 2025 | clinicaltrials |
| NCT06942143 | An Open-label, Phase I Clinical Trial of Super1 TCR-T in NY-ESO-1-positive Patients With Advanced Solid Tumors | recruiting | Phase 1 | 15 | Guangzhou FineImmune Biotechnology Co., LTD.INDUSTRY | 1 | Sep 3, 2025 | clinicaltrials |
| NCT06076005 | Characteristics of Advanced LUNG CANCER at the tIme of Diagnosis in a Large Italian Cohor(LUNG-CANCER) | recruiting | — | 1,000 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT06276530 | Impact of Surgical Approach on Adaptation of Posture-respiratory Coupling(VaPosVent) | recruiting | N/A | 50 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT06483698 | Real-world Clinical Outcomes of Patients With Early-stage Lung Cancer After the Surgery(EarlyLC-RW) | recruiting | — | 20,000 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Aug 29, 2025 | clinicaltrials |
| NCT06784791 | Preoperative Amivantamab or Amivantamab and Carboplatin/Pemetrexed Treatment in Patients With Resectable Non-small-cell Lung Cancer Harboring Oncogenic EGFR Mutations (NEOpredict-EGFR)(NEOpredict-EGF) | recruiting | Phase 2 | 20 | University Hospital, EssenOTHER | 3 | Aug 29, 2025 | clinicaltrials |
| NCT06529081 | Radiotherapy Strategies for Use in Combined Treatment of Small-cell Lung Cancer | recruiting | N/A | 165 | Copernicus Memorial HospitalOTHER | 1 | Aug 28, 2025 | clinicaltrials |
| NCT04527419 | SLND or Not in cT1 GGO Invasive Lung Adenocarcinoma (ECTOP-1009) | recruiting | N/A | 545 | Fudan UniversityOTHER | 1 | Aug 26, 2025 | clinicaltrials |
| NCT07056556 | A Study of BL-M09D1 in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer and Other Solid Tumors | recruiting | Phase 1 | 31 | Sichuan Baili Pharmaceutical Co., Ltd.INDUSTRY | 1 | Aug 22, 2025 | clinicaltrials |
| NCT06508307 | A Phase I Clinical Study of Intratumoral Injection Oncolytic Vaccinia Virus GC001 in Patient With Advanced Solid Tumors | recruiting | Phase 1 | 21 | GONGCHU Biotechnology Co., LtdOTHER | 1 | Aug 21, 2025 | clinicaltrials |
| NCT06258642 | Irinotecan Liposome Combined With Anlotinib as Second-line Regimen for SCLC | recruiting | N/A | 39 | Fudan UniversityOTHER | 1 | Aug 20, 2025 | clinicaltrials |
| NCT07131163 | Real World Stage II-III NSCLC Patients Receiving Neoadjuvant Chemo-immunotherapy and no Surgical Resection(NoSurgery) | recruiting | — | 60 | Sheba Medical CenterOTHER_GOV | 1 | Aug 20, 2025 | clinicaltrials |
| NCT07131670 | Symptoms Burden in Lung Cancer Patients Undergoing Definitive Chemoradiotherapy: Insights From Electronic Patient-Reported Outcomes(ePRO-LC-CRT) | recruiting | — | 100 | Qian ChuOTHER | 1 | Aug 20, 2025 | clinicaltrials |
| NCT07130032 | Efficacy And Safety Of Anti-PD-1/PD-L1 Antibodies In Combination With Bevacizumab And Metronomic Cyclophosphamide In Patients With Non-Small Cell Lung Cancer And Cutaneous Melanoma Previously Treated With Immune Checkpoint Blockade(reICB) | recruiting | Phase 2 | 90 | EuroCityClinic LLCNETWORK | 1 | Aug 19, 2025 | clinicaltrials |
| NCT07130916 | A Study of Aumolertinib in European Participants With Non-Small Cell Lung Cancer | recruiting | Phase 1 | 20 | Jiangsu Hansoh Pharmaceutical Co., Ltd.INDUSTRY | 3 | Aug 19, 2025 | clinicaltrials |
| NCT04429542 | Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors | recruiting | Phase 1 | 292 | Bicara TherapeuticsINDUSTRY | 3 | Aug 15, 2025 | clinicaltrials |
| NCT05049837 | PROSPECT - Profiling of Resistance Patterns & Oncogenic Signaling Pathways in Evaluation of Cancers of the Thorax and Therapeutic Target Identification | recruiting | — | 7,200 | M.D. Anderson Cancer CenterOTHER | 1 | Aug 15, 2025 | clinicaltrials |
| NCT06634979 | Selective Lymph Node Resection for Invasive Non-small Cell Lung Cancer With the CTR of 0.5-1 and the Diameter of ≤ 2 cm | recruiting | N/A | 684 | Fudan UniversityOTHER | 1 | Aug 12, 2025 | clinicaltrials |
| NCT06861543 | The Purpose of This Study is to Evaluate the Safety, Tolerability and Efficacy of TMT101 Injection Monotherapy in Patients With Advanced Pancreatic Cancer or Non-small Cell Lung Cancer(NSCLC)(TMT101-01) | recruiting | Phase 1 | 18 | Peking Union Medical College HospitalOTHER | 1 | Aug 11, 2025 | clinicaltrials |
| NCT07004868 | Inflammation, Cachexia and Therapeutic Response in Lung Cancer Treated With Immune Checkpoint Inhibitors: Exploratory Observational Study(LCab) | recruiting | — | 150 | University Hospital, ToursOTHER | 1 | Aug 11, 2025 | clinicaltrials |
| NCT06896422 | Randomized Trial of Glutathione With Anti-PD-1 and Chemotherapy in Advanced NSCLC | recruiting | Phase 1 | 80 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Aug 7, 2025 | clinicaltrials |
| NCT07109401 | Perioperative Immunotherapy for Resectable Limited-Stage SCLC | recruiting | Phase 2 | 37 | Fudan UniversityOTHER | 1 | Aug 7, 2025 | clinicaltrials |
| NCT06592638 | A Phase 1 Dose Escalation Study of ZG006 in Patients With Small Cell Lung Cancer | recruiting | Phase 1 | 30 | Suzhou Zelgen Biopharmaceuticals Co.,LtdINDUSTRY | 1 | Aug 6, 2025 | clinicaltrials |
| NCT07102589 | SWEEP: Shuttle Walking Test for Exercise Evaluation in Pulmonary Resection(SWEEP) | recruiting | — | 100 | Seoul National University Bundang HospitalOTHER | 1 | Aug 4, 2025 | clinicaltrials |
| NCT05442060 | To Evaluate OBI-833/OBI-821 in Combination With First-Line Erlotinib in Patients With EGFR-Mutated, Globo H-Positive, Locally Advanced or Metastatic Non-Small Cell Lung Cancer(EGFR) | recruiting | Phase 2 | 60 | OBI Pharma, IncINDUSTRY | 1 | Aug 3, 2025 | clinicaltrials |
| NCT04706754 | Pan-Canadian Lung Cancer Observational Study (PALEOS) | recruiting | — | 25,000 | William Osler Health SystemOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT06417008 | A Study of HS-20117 Combined With Aumolertinib in Participants With Advanced Non-Squamous Non-Small Cell Lung Cancer | recruiting | Phase 2 / Phase 3 | 1,080 | Hansoh BioMedical R&D CompanyINDUSTRY | 1 | Aug 1, 2025 | clinicaltrials |
| NCT06462963 | OligoCare TwiCs (Trials Within Cohorts) Trial Comparing Acute Toxicity in Single-fraction vs Multiple-fraction SBRT for Metastasis-directed Treatment (SPRINT)(SPRINT) | recruiting | N/A | 302 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 4 | Aug 1, 2025 | clinicaltrials |
| NCT06691776 | Feasibility of CBCT-Guided Online Adaptive Radiotherapy (FASCINATE)(FASCINATE) | recruiting | N/A | 100 | The Netherlands Cancer InstituteOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT06897046 | Perioperative Study of Iparomlimab and Tuvonralimab in Resectable NSCLC | recruiting | Phase 2 | 90 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT07099027 | The Lung Health Check Pilot | recruiting | N/A | 2,183 | Royal College of Surgeons, IrelandOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT04209218 | Intraoperative Blood Pressure Management and Dexamethasone in Lung Cancer Surgery | recruiting | N/A | 1,988 | Peking University First HospitalOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT07087080 | Plasma Metabolomics as a Tool to Distinguish PET-positive Malignant From PET-positive Benign Nodules | recruiting | N/A | 350 | Hasselt UniversityOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT07096258 | EMPATHY NSCLC: European Registry for Plasma-Based Molecular Profiling in Advanced NSCLC Patients(EMPATHY NSCLC) | recruiting | — | 1,000 | Hedera Dx SAINDUSTRY | 4 | Jul 31, 2025 | clinicaltrials |
| NCT07096882 | SDTM001 Injection as Adjuvant Therapy for NSCLC Patients After Radical Surgical Resection | recruiting | Phase 1 | 22 | Cytocraft Biopharmaceutical Co., Ltd.INDUSTRY | 1 | Jul 31, 2025 | clinicaltrials |
| NCT07014202 | Consolidation Radiotherapy vs. Observation in Oligoresidual Advanced Non-Small Cell Lung Cancer After Chemo-Immunotherapy | recruiting | Phase 2 | 224 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Jul 30, 2025 | clinicaltrials |
| NCT07092202 | Firmonertinib Combined With Intrathecal Injection for the Treatment of EGFR Mutant NSCLC With Leptomeningeal Metastases | recruiting | Phase 4 | 40 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Jul 29, 2025 | clinicaltrials |
| NCT06864624 | Perioperative Treatment of Sunvozertinib in Stage II-IIIB NSCLC(WU-KONG20) | recruiting | Phase 2 | 27 | Tang-Du HospitalOTHER | 1 | Jul 25, 2025 | clinicaltrials |
| NCT07085182 | Tislelizumab Combined With sCRT in Stage IIIB/C-IV Non-Squamous Non-Small Cell Lung Cancer：A Prospective, Single-Arm, Phase II Study | recruiting | Phase 2 | 20 | Zibo Municipal HospitalOTHER | 1 | Jul 25, 2025 | clinicaltrials |
| NCT07086300 | Electroacupuncture Combined With PD-1 Inhibitor for Elderly Patients With Advanced NSCLC | recruiting | N/A | 120 | Kong FanmingOTHER | 1 | Jul 25, 2025 | clinicaltrials |
Data updated 24 days agoSource updated Sep 9, 2025source: clinicaltrials