Cancer Family
Malignant Respiratory System Neoplasm
CI-CAN-00000249Explore in graph →
2,650 active trials51 approved drugs619 evidence items
- NCIt
- C4571
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Cancer Family
CI-CAN-00000249Explore in graph →
Clinical trials
11,128 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (1,492)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03299088 | Pembrolizumab and Trametinib in Treating Patients With Stage IV Non-Small Cell Lung Cancer and KRAS Gene Mutations | completed | Phase 1 | 15 | Jonathan RiessOTHER | 1 | May 21, 2025 | clinicaltrials |
| NCT03845296 | Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial) | completed | Phase 2 | 64 | SWOG Cancer Research NetworkNETWORK | 1 | May 21, 2025 |
| NCT03929926 | Proactive Outreach and Shared Decision Making in Improving Lung Cancer Screening Rates in Primary Care Patients | completed | N/A | 2,355 | Thomas Jefferson UniversityOTHER | 1 | May 20, 2025 | clinicaltrials |
| NCT04121286 | A Study of JAB-3312 in Adult Patients With Advanced Solid Tumors in China | completed | Phase 1 | 17 | Allist Pharmaceuticals, Inc.INDUSTRY | 1 | May 20, 2025 | clinicaltrials |
| NCT04969341 | Improving Lung Cancer Screening Adherence by Overcoming Barriers for Vulnerable Populations | completed | — | 947 | Thomas Jefferson UniversityOTHER | 1 | May 20, 2025 | clinicaltrials |
| NCT06304805 | TGRX-326 Pharmacokinetic Food Effect Bioavailability Study | completed | Phase 1 | 24 | Shenzhen TargetRx Co., Ltd.INDUSTRY | 1 | May 18, 2025 | clinicaltrials |
| NCT03375489 | Early Integrated Telehealth Versus In-Person Palliative Care for Patients With Lung Cancer(REACH PC) | completed | N/A | 1,798 | Massachusetts General HospitalOTHER | 1 | May 16, 2025 | clinicaltrials |
| NCT03704688 | Trial of Trametinib and Ponatinib in Patients With KRAS Mutant Advanced Non-Small Cell Lung Cancer | completed | Phase 1 / Phase 2 | 12 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 16, 2025 | clinicaltrials |
| NCT02245100 | Circulating Tumor DNA in Predicting Outcomes in Patients With Stage IV Head and Neck Cancer or Stage III-IV Non-small Cell Lung Cancer | completed | — | 130 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT02318771 | Radiation Therapy and MK-3475 for Patients With Recurrent/Metastatic Head and Neck Cancer, Renal Cell Cancer, Melanoma, and Lung Cancer | completed | Phase 1 | 41 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT03340714 | Automated Device for Asthma Monitoring and Management in Monitoring Adults With Lung Cancer Undergoing Radiation Therapy | completed | — | 24 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT03755102 | A Pilot Study of Dacomitinib With or Without Osimertinib for Patients With Metastatic EGFR Mutant Lung Cancers With Disease Progression on Osimertinib. | completed | Early Phase 1 | 17 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT03784378 | Continued Access to RXDX-105 | completed | Phase 1 | 3 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT04826575 | Pre-habilitation in Lung Surgery Candidates | completed | N/A | 150 | St. Anne's University Hospital Brno, Czech RepublicOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT04553809 | Navigation Endobronchial Ultrasound(NEBULA) | completed | N/A | 200 | Amanda Dandanell JuulOTHER | 1 | May 14, 2025 | clinicaltrials |
| NCT04383938 | Phase 1/2 Study of APR-246 in Combination With Pembrolizumab in Subjects With Solid Tumor Malignancies | completed | Phase 1 / Phase 2 | 40 | Aprea TherapeuticsINDUSTRY | 1 | May 13, 2025 | clinicaltrials |
| NCT05270395 | Piloting 'mPal,' a Multilevel Strategy for Palliative Care Implementation | completed | N/A | 75 | Laurie McLouthOTHER | 1 | May 13, 2025 | clinicaltrials |
| NCT01880515 | Tetracycline as a Prophylaxis for Rash in Patients With NSCLC Receiving Treatment With BIBW2992 (Afatinib) | completed | Phase 2 | 107 | Instituto Nacional de Cancerologia de MexicoOTHER | 1 | May 11, 2025 | clinicaltrials |
| NCT04671303 | To Evaluate the Efficacy and Safety of Anlotinib Combined With Furmonertinib Mesylate in Lung Cancer | completed | Phase 2 | 36 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | May 11, 2025 | clinicaltrials |
| NCT04993677 | A Study of SEA-CD40 Given With Other Drugs in Cancers | completed | Phase 2 | 77 | Seagen Inc.INDUSTRY | 6 | May 11, 2025 | clinicaltrials |
| NCT03554473 | M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers | completed | Phase 1 / Phase 2 | 37 | National Cancer Institute (NCI)NIH | 1 | May 9, 2025 | clinicaltrials |
| NCT04967417 | Pembrolizumab With Standard Cytotoxic Chemotherapy in Treatment Naive NSCLC Patients With Asymptomatic Brain Metastases(PHOEBS) | completed | Phase 2 | 13 | Samsung Medical CenterOTHER | 1 | May 9, 2025 | clinicaltrials |
| NCT06964698 | Optimizing Post-Thoracotomy Pain Management: Comparing Erector Spinae vs. Paravertebral Block in Thoracotomy Patients | completed | — | 60 | Başakşehir Çam & Sakura City HospitalOTHER_GOV | 1 | May 9, 2025 | clinicaltrials |
| NCT03212469 | A Trial of Durvalumab and Tremelimumab in Combination With SBRT in Patients With Metastatic Cancer(ABIMMUNE) | completed | Phase 1 / Phase 2 | 54 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 1 | May 8, 2025 | clinicaltrials |
| NCT06751576 | Retrospective Clinical Trial Comparing Radiologists' Diagnosis Accuracy in Lung Cancer Screening Population With and Without the Help of an AI/ML Tech-based SaMD(RELIVE) | completed | — | 480 | Median TechnologiesINDUSTRY | 2 | May 6, 2025 | clinicaltrials |
| NCT06958614 | Prophylactic PEG-rhG-CSF During cCRT in LA-NSCLC | completed | — | 213 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | May 6, 2025 | clinicaltrials |
| NCT00328562 | ZD1839 With Hypofractionated Radiation Therapy With an Immobilization Device for Advanced Non-Small Cell Lung Cancer | completed | Phase 1 | 13 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 4, 2025 | clinicaltrials |
| NCT01068210 | Lung Cancer Exercise Training Study | completed | N/A | 110 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 4, 2025 | clinicaltrials |
| NCT06953492 | Sleep State in Lung Cancer: A Retrospective Analysis | completed | — | 300 | Shanghai Zhongshan HospitalOTHER | 1 | May 1, 2025 | clinicaltrials |
| NCT00983307 | A Study of Erlotinib Plus Radiotherapy (RT) for Patients With Advanced or Inoperable Non-Small-Cell Lung Cancer | completed | Phase 2 | 17 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | Apr 30, 2025 | clinicaltrials |
| NCT02016872 | Prognostic Value of Tumor Hypoxia, as Measured by 18F-FMISO Breath Hold PET/CT, in Non-Small-Cell-Lung Cancer (NSCLC) Patients | completed | N/A | 25 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Apr 30, 2025 | clinicaltrials |
| NCT05628454 | Comparison of Three Different Puncture Techniques in EBUS-TBNA | completed | N/A | 75 | Beijing Friendship HospitalOTHER | 1 | Apr 30, 2025 | clinicaltrials |
| NCT06950996 | A Clinical Evaluation of AI Solutions Developed in the CHAIMELEON Project for Cancer: Prostate, Lung, Breast, Colon and Rectum | completed | — | 300 | Instituto de Investigacion Sanitaria La FeOTHER | 1 | Apr 30, 2025 | clinicaltrials |
| NCT03054298 | CAR T Cells in Mesothelin Expressing Cancers | completed | Phase 1 | 65 | University of PennsylvaniaOTHER | 1 | Apr 29, 2025 | clinicaltrials |
| NCT03820557 | Decision Counseling Program in Increasing Shared Decision Making and Clinical Trial Participation in Patients With Stage 0-IV Lung Cancer (Free to Breathe) | completed | N/A | 44 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | Apr 29, 2025 | clinicaltrials |
| NCT03944265 | Genetics and Shared Decision Making in Improving Care for Patients With Stage IVA-C Non-small Cell Lung Cancer | completed | N/A | 14 | Thomas Jefferson UniversityOTHER | 1 | Apr 29, 2025 | clinicaltrials |
| NCT04075396 | A Study of Lazertinib in Participants With Epidermal Growth Factor Receptor (EGFR) Mutation Positive Advanced Non-Small Cell Lung Cancer (NSCLC) | completed | Phase 1 / Phase 2 | 29 | Janssen Research & Development, LLCINDUSTRY | 3 | Apr 29, 2025 | clinicaltrials |
| NCT04078269 | MIDRIXNEO-LUNG Dendritic Cell Vaccine in Patients With Non-small Cell Lung Cancer(MIDRIXNEO) | completed | Phase 1 | 6 | University Hospital, GhentOTHER | 1 | Apr 29, 2025 | clinicaltrials |
| NCT04049474 | Bronchoscopic Cryo-Immunotherapy of Lung Cancer | completed | Early Phase 1 | 21 | NYU Langone HealthOTHER | 1 | Apr 24, 2025 | clinicaltrials |
| NCT05937399 | Project PLUS Lung Cancer Screening Promotion | completed | N/A | 34 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Apr 22, 2025 | clinicaltrials |
| NCT00026754 | Eligibility Screening for the NIH Intramural Research Program Clinical Protocols | completed | — | 19,522 | National Cancer Institute (NCI)NIH | 1 | Apr 18, 2025 | clinicaltrials |
| NCT02496585 | Study to Evaluate the Efficacy and Safety of Nintedanib (BIBF 1120) + Prednisone Taper in Patients With Radiation Pneumonitis | completed | Phase 2 | 34 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Apr 16, 2025 | clinicaltrials |
| NCT04776291 | Correlation of Pre- and Post-operative Cancer Imaging Techniques | completed | N/A | 7 | University of StrathclydeOTHER | 1 | Apr 16, 2025 | clinicaltrials |
| NCT03250390 | Breath Analysis to Diagnose Lung Cancer(CATOCOV) | completed | N/A | 1,500 | University Hospital, LilleOTHER | 1 | Apr 15, 2025 | clinicaltrials |
| NCT02487095 | Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers | completed | Phase 1 / Phase 2 | 62 | National Cancer Institute (NCI)NIH | 1 | Apr 13, 2025 | clinicaltrials |
| NCT01853826 | An Open Label Trial of Afatinib (Giotrif) in Treatment-naive (1st Line) or Chemotherapy Pre-treated Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Harboring EGFR Mutation(s) | completed | Phase 3 | 481 | Boehringer IngelheimINDUSTRY | 11 | Apr 11, 2025 | clinicaltrials |
| NCT04720976 | JAB-3312 Based Combination Therapy in Adult Patients With Advanced Solid Tumors | completed | Phase 1 / Phase 2 | 58 | Allist Pharmaceuticals, Inc.INDUSTRY | 1 | Apr 11, 2025 | clinicaltrials |
| NCT03301493 | Genomic Testing and Resulting Medical Decisions | completed | — | 1,500 | Arbeitsgemeinschaft medikamentoese TumortherapieOTHER | 1 | Apr 10, 2025 | clinicaltrials |
| NCT03631706 | M7824 Versus Pembrolizumab as a First-line (1L) Treatment in Participants With Programmed Death-ligand 1 (PD-L1) Expressing Advanced Non-small Cell Lung Cancer (NSCLC) | completed | Phase 3 | 304 | EMD Serono Research & Development Institute, Inc.INDUSTRY | 18 | Apr 8, 2025 | clinicaltrials |
| NCT04568564 | Telerehabilitation in Lung Surgery Patients | completed | N/A | 40 | Istanbul Medipol University HospitalOTHER | 1 | Apr 8, 2025 | clinicaltrials |
Data updated 24 days agoSource updated May 21, 2025source: clinicaltrials