Cancer Family
Malignant Nervous System Neoplasm
CI-CAN-00000246Explore in graph →
953 active trials7 approved drugs131 evidence items
- NCIt
- C4788
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Cancer Family
CI-CAN-00000246Explore in graph →
Clinical trials
3,457 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (494)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05021770 | Orelabrutinib in Combination With Thiotepa in Refractory and Relapsed Primary CNS Lymphoma | unknown | Phase 1 / Phase 2 | 29 | Huiqiang HuangOTHER | 1 | Aug 26, 2021 | clinicaltrials |
| NCT03347097 | Adoptive Cell Therapy of Autologous TIL and PD1-TIL Cells for Patients With Glioblastoma Multiforme | unknown | Early Phase 1 | 40 | Huashan HospitalOTHER | 1 | Aug 25, 2021 | clinicaltrials |
| NCT04728568 |
| Exploratory Study of PD-1 Neoadjuvant Treatment of Recurrent Meningioma |
| unknown |
| N/A |
| 15 |
| Beijing Tiantan HospitalOTHER |
| 1 |
| Aug 10, 2021 |
| clinicaltrials |
| NCT04990271 | A Clinical Study on the Efficacy and Safety of VEC Intravenous Chemotherapy Combined With Conbercept Intravitreal Injection in the Treatment of Retinoblastoma | unknown | Phase 2 | 92 | Chengdu Kanghong Biotech Co., Ltd.INDUSTRY | 1 | Aug 4, 2021 | clinicaltrials |
| NCT04970615 | Educating Brain Tumor Patients Using Patient-specific Actual-size Three-dimensional Printed Models(IMAGE-3D) | unknown | — | 60 | Sümeyye SezerOTHER | 1 | Jul 21, 2021 | clinicaltrials |
| NCT04129710 | A Trial to Compare Ibrutinib Versus Lenalidomide in Combination With MRE-chemotherapy for Adult Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL) | unknown | Phase 2 | 120 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Jul 16, 2021 | clinicaltrials |
| NCT04856852 | Iodine-125 Brachytherapy Together With Chemotherapy in Patients With Newly Diagnosed Glioblastoma(IBCNG) | unknown | N/A | 84 | The Affiliated Hospital of Qingdao UniversityOTHER | 0 | Jun 29, 2021 | clinicaltrials |
| NCT04943718 | Personalized Vaccine for Patients With Recurrent Malignant Glioma | unknown | Phase 1 | 10 | Xuanwu Hospital, BeijingOTHER | 1 | Jun 29, 2021 | clinicaltrials |
| NCT04944069 | Almonertinib With Bevacizumab for EGFR-Mutant NSCLC Patients With Leptomeningeal Metastasis(ATTRACT) | unknown | N/A | 69 | Second Affiliated Hospital of Nanchang UniversityOTHER | 1 | Jun 29, 2021 | clinicaltrials |
| NCT04938297 | Rituximab,Zanubrutinib in Combination With Lenalidomide, Followed by Zanubrutinib or Lenalidomide Maintenance in Patients With Primary or Secondary CNS Lymphoma | unknown | Phase 2 | 100 | Henan Cancer HospitalOTHER_GOV | 1 | Jun 24, 2021 | clinicaltrials |
| NCT04902586 | Effect of Radiotherapy Concurrent of TTFields in Patients With Glioblastoma(ECTG001) | unknown | N/A | 30 | Zhongnan HospitalOTHER | 1 | May 26, 2021 | clinicaltrials |
| NCT04899427 | Phase II Study of Orelabrutinib Combined With PD-1 Inhibitor in Relapsed/Refractory Primary Central Nervous System Lymphoma | unknown | Phase 2 | 32 | Peking Union Medical College HospitalOTHER | 1 | May 24, 2021 | clinicaltrials |
| NCT04899453 | Intravitreal MTX and ZR Regimen in Newly Diagnosed PVRL | unknown | Phase 2 | 42 | Peking Union Medical College HospitalOTHER | 1 | May 24, 2021 | clinicaltrials |
| NCT03008148 | Phase II/III Trial of CCRT With or Without JP001 for Newly Diagnosed GBM | unknown | Phase 2 / Phase 3 | 288 | Johnpro Biotech, Inc.INDUSTRY | 1 | May 11, 2021 | clinicaltrials |
| NCT04864821 | Clinical Study of CD276 Targeted Autologous Chimeric Antigen Receptor T Cell Infusion in Patients With CD276 Positive Advanced Solid Tumor | unknown | Early Phase 1 | 24 | PersonGen BioTherapeutics (Suzhou) Co., Ltd.INDUSTRY | 0 | May 6, 2021 | clinicaltrials |
| NCT04874506 | MBM-02 (Tempol) for the Treatment of Glioblastoma Multiforme (GBM) | unknown | Phase 2 | 55 | Matrix Biomed, Inc.INDUSTRY | 1 | May 5, 2021 | clinicaltrials |
| NCT03025893 | A Phase II/III Study of High-dose, Intermittent Sunitinib in Patients With Recurrent Glioblastoma Multiforme(STELLAR) | unknown | Phase 2 / Phase 3 | 100 | Amsterdam UMC, location VUmcOTHER | 1 | Apr 19, 2021 | clinicaltrials |
| NCT04829097 | Neoadjuvant Temozolomide Combined With Simultaneous IMRT for Treatment of Glioblastoma | unknown | Phase 3 | 80 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolOTHER | 1 | Apr 2, 2021 | clinicaltrials |
| NCT04772846 | Chloroquine for Glioblastoma. | unknown | Phase 1 / Phase 2 | 60 | Egyptian Medical SyndicateOTHER | 1 | Feb 26, 2021 | clinicaltrials |
| NCT00790413 | Haploidentical Stem Cell Transplantation in Neuroblastoma | unknown | Early Phase 1 | 15 | Lund University HospitalOTHER | 1 | Feb 21, 2021 | clinicaltrials |
| NCT03989596 | Hypofractionated Radiotherapy With Hyperthermia in Unresectable or Marginally Resectable Soft Tissue Sarcomas(SINDIR) | unknown | Phase 2 | 30 | Maria Sklodowska-Curie National Research Institute of OncologyOTHER | 1 | Feb 1, 2021 | clinicaltrials |
| NCT03258021 | TTFields In GErmany in Routine Clinical Care(TIGER) | unknown | — | 710 | NovoCure Ltd.INDUSTRY | 1 | Jan 28, 2021 | clinicaltrials |
| NCT02904525 | Glioblastoma: Validation and Comparison Between Primary Tumor and Its Murine Model(XENOGBM) | unknown | N/A | 20 | Andreas HottingerOTHER | 1 | Jan 27, 2021 | clinicaltrials |
| NCT04588454 | 18F-PSMA PET/CT for Visualization of Glioblastoma Multiforme(PSMA-GBM) | unknown | N/A | 5 | Radboud University Medical CenterOTHER | 1 | Jan 27, 2021 | clinicaltrials |
| NCT04017104 | Dynamic Whole Body Positron Emission Tomography/Computed Tomography Imaging | unknown | — | 60 | British Columbia Cancer AgencyOTHER | 1 | Jan 26, 2021 | clinicaltrials |
| NCT04725214 | Anlotinib Combined With STUPP for MGMT Nonmethylated Glioblastoma | unknown | Phase 2 | 33 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Jan 26, 2021 | clinicaltrials |
| NCT03651375 | Hypofractionated Radiotherapy With Sequential Chemotherapy in Marginally Resectable Soft Tissue Sarcomas of Extremities or Trunk Wall(UN-RESARC) | unknown | Phase 2 | 46 | Maria Sklodowska-Curie National Research Institute of OncologyOTHER | 1 | Jan 22, 2021 | clinicaltrials |
| NCT04717999 | Pilot Study of NKG2D CAR-T in Treating Patients With Recurrent Glioblastoma | unknown | N/A | 20 | UWELL BiopharmaINDUSTRY | 0 | Jan 22, 2021 | clinicaltrials |
| NCT04715620 | Niraparib Combined With Radiotherapy in rGBM | unknown | Phase 2 | 30 | Tianjin Huanhu HospitalOTHER | 1 | Jan 20, 2021 | clinicaltrials |
| NCT04689087 | A Prospective, Open-label, Single-arm Clinical Study | unknown | N/A | 40 | Sun Yat-sen UniversityOTHER | 1 | Dec 30, 2020 | clinicaltrials |
| NCT04674527 | Pilot Study of Elemene in Treating Patients With Refractory Glioblastoma | unknown | Phase 2 | 30 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Dec 19, 2020 | clinicaltrials |
| NCT04674579 | Automatic Segmentation MRI Cerebral Glioma | unknown | — | 50 | Assiut UniversityOTHER | 0 | Dec 19, 2020 | clinicaltrials |
| NCT04668508 | Anlotinib to Malignant Brainstem Glioma | unknown | Phase 2 | 25 | Zhejiang Cancer HospitalOTHER | 1 | Dec 16, 2020 | clinicaltrials |
| NCT03896958 | The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)(PIONEER) | unknown | — | 1,000 | SpeciCareINDUSTRY | 1 | Dec 4, 2020 | clinicaltrials |
| NCT04583020 | Neoadjuvant PD-1 in Newly Diagnosed Glioblastoma | unknown | Phase 2 | 42 | Peking Union Medical College HospitalOTHER | 1 | Nov 30, 2020 | clinicaltrials |
| NCT04174820 | Child's Study of the Impact of PF Lesion on Motor Skills, Language, Cognitive Functioning and Social Cognition(CervIRM) | unknown | — | 145 | University Hospital, AngersOTHER_GOV | 1 | Nov 19, 2020 | clinicaltrials |
| NCT03569995 | [CREMA]Combination of R-M Followed by R-A in Elderly Patients With Primary CNS Lymphoma | unknown | Phase 2 | 35 | Won Seog KimOTHER | 1 | Oct 22, 2020 | clinicaltrials |
| NCT04457869 | A Study of F520 in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) or Secondary Central Nervous System Lymphoma (SCNSL) | unknown | Phase 2 | 43 | Shandong New Time Pharmaceutical Co., LTDINDUSTRY | 0 | Oct 22, 2020 | clinicaltrials |
| NCT03903419 | Feasibility Study of 68Ga-PSMA PET-CT and 18F-FDOPA PET-CT in Glioblastoma's Patients(PAraDiGM) | unknown | N/A | 16 | Centre Leon BerardOTHER | 1 | Oct 14, 2020 | clinicaltrials |
| NCT03463733 | Hydroxy-urea and Temozolomide in Patients With a Recurrent Malignant Brain Tumor (Glioblastoma)(HUTMZ) | unknown | Phase 1 | 54 | M.E. van LindeOTHER | 1 | Oct 8, 2020 | clinicaltrials |
| NCT04562077 | Role of Surgery in Treatment of Recurrent Brian Glioma:Prognostic Factors and Outcome | unknown | — | 25 | Assiut UniversityOTHER | 1 | Sep 24, 2020 | clinicaltrials |
| NCT04552977 | A Trail of Fluzoparil in Combination With Temozolomide in Patients With Recurrent Glioblastoma | unknown | Phase 2 | 50 | Shandong Cancer Hospital and InstituteOTHER | 0 | Sep 17, 2020 | clinicaltrials |
| NCT04547621 | HSRT and IMRT Chemoradiotherapy for Newly Diagnosed GBM(HSCK-010) | unknown | Phase 1 / Phase 2 | 50 | Huashan HospitalOTHER | 1 | Sep 14, 2020 | clinicaltrials |
| NCT04547855 | Anlotinib Combined With Dose-dense Temozolomide for the First Recurrent or Progressive Glioblastoma After STUPP Regimen | unknown | Phase 2 | 54 | Yonggao MouOTHER | 1 | Sep 14, 2020 | clinicaltrials |
| NCT01567202 | Study of DC Vaccination Against Glioblastoma | unknown | Phase 2 | 100 | Huashan HospitalOTHER | 1 | Sep 9, 2020 | clinicaltrials |
| NCT04536649 | Proton and Heavy Ion Beam Radiation vs. Photon Beam Radiation for Newly Diagnosed Glioblastoma. | unknown | Phase 3 | 369 | Shanghai Proton and Heavy Ion CenterOTHER | 1 | Sep 2, 2020 | clinicaltrials |
| NCT04516655 | A Phase II Trail of Chidamide ,Rituximab and Methotrexate in Lymphoma Patients(C-R-HDMTX) | unknown | Phase 2 | 51 | Fudan UniversityOTHER | 0 | Aug 18, 2020 | clinicaltrials |
| NCT04488783 | Potentiation of Chemotherapy in Brain Tumors by Zinc | unknown | N/A | 30 | Sheba Medical CenterOTHER_GOV | 1 | Jul 28, 2020 | clinicaltrials |
| NCT03734913 | A Phase 1 Study of ZSP1602 in Participants With Advanced Solid Tumors | unknown | Phase 1 | 65 | Guangdong Zhongsheng Pharmaceutical Co., Ltd.INDUSTRY | 1 | Jul 22, 2020 | clinicaltrials |
| NCT01701479 | Long Term Continuous Infusion ch14.18/CHO Plus s.c. Aldesleukin (IL-2)(LTI) | unknown | Phase 1 / Phase 2 | 288 | St. Anna KinderkrebsforschungOTHER | 7 | Jul 14, 2020 | clinicaltrials |
Data updated 23 days agoSource updated Aug 26, 2021source: clinicaltrials