Cancer Family
Malignant Nervous System Neoplasm
CI-CAN-00000246Explore in graph →
953 active trials7 approved drugs131 evidence items
- NCIt
- C4788
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Cancer Family
CI-CAN-00000246Explore in graph →
Clinical trials
3,457 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (494)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01231919 | MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia | completed | Phase 1 | 45 | National Cancer Institute (NCI)NIH | 2 | Apr 29, 2014 | clinicaltrials |
| NCT00677716 | Dose Confirmation Study of Cotara for the Treatment of Glioblastoma Multiforme at First Relapse | completed | Phase 2 | 41 | Peregrine PharmaceuticalsINDUSTRY | 2 | Apr 24, 2014 | clinicaltrials |
| NCT00397072 | Epothilone in Recurrent Glioblastoma Patients | completed | Phase 2 | 15 | Fondazione I.R.C.C.S. Istituto Neurologico Carlo BestaOTHER | 1 | Apr 17, 2014 | clinicaltrials |
| NCT00822458 | GDC-0449 in Treating Young Patients With Medulloblastoma That is Recurrent or Did Not Respond to Previous Treatment | completed | Phase 1 | 34 | National Cancer Institute (NCI)NIH | 1 | Apr 2, 2014 | clinicaltrials |
| NCT00003141 | Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors | completed | Phase 1 | 94 | Children's Oncology GroupNETWORK | 3 | Mar 28, 2014 | clinicaltrials |
| NCT00979017 | Avastin/Temozolomide/Irinotecan for Unresectable/Multifocal Glioblastoma Multiforme | completed | Phase 2 | 41 | Katy PetersOTHER | 1 | Mar 19, 2014 | clinicaltrials |
| NCT00657267 | Dose-Intense Temozolomide in Recurrent Glioblastoma | completed | Phase 2 | 58 | Patrick Y. Wen, MDOTHER | 1 | Mar 14, 2014 | clinicaltrials |
| NCT00611325 | Phase II Avastin + Bortezomib for Patients With Recurrent Malignant Glioma | completed | Phase 2 | 56 | Duke UniversityOTHER | 1 | Mar 12, 2014 | clinicaltrials |
| NCT00337883 | A Study of the Safety and Efficacy of Tarceva in Patients With First Relapse of Grade IV Glioma (Glioblastoma Multiforme) | completed | Phase 2 | 110 | Genentech, Inc.INDUSTRY | 0 | Mar 4, 2014 | clinicaltrials |
| NCT01017250 | Radiosurgery and Avastin for Recurrent Malignant Gliomas | completed | N/A | 15 | Duke UniversityOTHER | 1 | Feb 28, 2014 | clinicaltrials |
| NCT00499811 | Vorinostat in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphoma and Liver Dysfunction | completed | Phase 1 | 15 | National Cancer Institute (NCI)NIH | 1 | Feb 24, 2014 | clinicaltrials |
| NCT00002485 | Development of Strategies to Increase Enrollment in Clinical Trials for Children With Cancer | completed | — | 359 | Children's Oncology GroupNETWORK | 4 | Feb 14, 2014 | clinicaltrials |
| NCT00017368 | Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Neuroblastoma | completed | Phase 2 | 42 | Children's Oncology GroupNETWORK | 2 | Feb 13, 2014 | clinicaltrials |
| NCT00070200 | Induction Chemotherapy Using Cyclophosphamide and Topotecan in Treating Patients Who Are Undergoing Autologous Peripheral Stem Cell Transplantation for Newly Diagnosed or Progressive Neuroblastoma | completed | Phase 1 | 31 | Children's Oncology GroupNETWORK | 2 | Feb 13, 2014 | clinicaltrials |
| NCT01048892 | Seneca Valley Virus-001 and Cyclophosphamide in Treating Young Patients With Relapsed or Refractory Neuroblastoma, Rhabdomyosarcoma, or Rare Tumors With Neuroendocrine Features | completed | Phase 1 | 22 | Children's Oncology GroupNETWORK | 1 | Jan 30, 2014 | clinicaltrials |
| NCT00387920 | Sunitinib in Treating Young Patients With Refractory Solid Tumors | completed | Phase 1 | 35 | National Cancer Institute (NCI)NIH | 2 | Jan 28, 2014 | clinicaltrials |
| NCT00575887 | Efficacy of Protracted Temozolomide in Patients With Progressive High Grade Glioma | completed | Phase 2 | 25 | Marmara UniversityOTHER | 1 | Dec 20, 2013 | clinicaltrials |
| NCT00002802 | Therapy Based on Stage of Disease and Risk Assessment in Treating Children With Neuroblastoma | completed | Phase 3 | 500 | Children's Hospital Medical Center, CincinnatiOTHER | 1 | Dec 19, 2013 | clinicaltrials |
| NCT00002803 | Combination Chemotherapy or Observation Following Surgery in Treating Infants With Neuroblastoma | completed | Phase 2 | 44 | Children's Hospital Medical Center, CincinnatiOTHER | 1 | Dec 19, 2013 | clinicaltrials |
| NCT00028522 | R(+)XK469 in Treating Patients With Advanced Neuroblastoma | completed | Phase 1 | 85 | National Cancer Institute (NCI)NIH | 1 | Dec 16, 2013 | clinicaltrials |
| NCT00025428 | Combination Chemotherapy Before Surgery in Treating Children With Localized Neuroblastoma | completed | Phase 3 | 100 | Societe Internationale d'Oncologie PediatriqueOTHER | 12 | Dec 4, 2013 | clinicaltrials |
| NCT00921167 | A Study to Evaluate the Efficacy of Bevacizumab Plus Irinotecan in Recurrent Gliomas | completed | Phase 2 | 32 | Clinical Research Center for Solid Tumor, KoreaOTHER | 1 | Dec 4, 2013 | clinicaltrials |
| NCT00431561 | Phase IIb Clinical Trial With TGF-β2 Antisense Compound AP 12009 for Recurrent or Refractory High-grade Glioma | completed | Phase 2 | 141 | Isarna Therapeutics GmbHINDUSTRY | 6 | Dec 3, 2013 | clinicaltrials |
| NCT00004110 | Monoclonal Antibody Therapy Plus Etoposide in Treating Patients With Neuroblastoma | completed | Phase 2 | — | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Oct 31, 2013 | clinicaltrials |
| NCT00919737 | Study of NPC-08 is to Treat for Newly-Diagnosed Malignant Glioma and Recurrent Glioblastoma Multiforme | completed | Phase 1 / Phase 2 | 24 | NobelpharmaINDUSTRY | 1 | Oct 30, 2013 | clinicaltrials |
| NCT00610571 | Ph I Oral Topotecan and Temozolomide for Patients With Malignant Gliomas | completed | Phase 1 | 62 | Katy PetersOTHER | 1 | Oct 25, 2013 | clinicaltrials |
| NCT00385853 | PTK787/ZK 222584 in Combination With Temozolomide and Radiation in Patients With Glioblastoma Taking Enzyme-Inducing Anti-Epileptic Drugs | completed | Phase 1 | 19 | Massachusetts General HospitalOTHER | 1 | Oct 21, 2013 | clinicaltrials |
| NCT01135875 | Laboratory Study of Early Tumor Markers in the Peripheral Blood of Glioblastoma Multiforme Patients | completed | — | 130 | University of FloridaOTHER | 1 | Oct 17, 2013 | clinicaltrials |
| NCT00450307 | Monoclonal Antibody 3F8 and GM-CSF in Treating Young Patients With High-Risk, Refractory or Relapsed Neuroblastoma | completed | Phase 1 | 32 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Oct 16, 2013 | clinicaltrials |
| NCT00053326 | Fenretinide in Treating Children With Recurrent or Resistant Neuroblastoma | completed | Phase 2 | 70 | National Cancer Institute (NCI)NIH | 1 | Oct 8, 2013 | clinicaltrials |
| NCT00070525 | Tipifarnib in Treating Young Patients With Recurrent or Progressive High-Grade Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, or Brain Stem Glioma | completed | Phase 2 | 90 | National Cancer Institute (NCI)NIH | 1 | Oct 8, 2013 | clinicaltrials |
| NCT00052780 | Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors | completed | Phase 1 | 72 | National Cancer Institute (NCI)NIH | 1 | Sep 30, 2013 | clinicaltrials |
| NCT00063973 | Cilengitide in Treating Children With Refractory Primary Brain Tumors | completed | Phase 1 | 24 | National Cancer Institute (NCI)NIH | 1 | Sep 30, 2013 | clinicaltrials |
| NCT00075634 | Decitabine, Doxorubicin, and Cyclophosphamide in Treating Children With Relapsed or Refractory Solid Tumors or Neuroblastoma | completed | Phase 1 | 21 | National Cancer Institute (NCI)NIH | 1 | Sep 30, 2013 | clinicaltrials |
| NCT00100880 | Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors | completed | Phase 1 | 45 | National Cancer Institute (NCI)NIH | 1 | Sep 30, 2013 | clinicaltrials |
| NCT00293345 | 3-AP and Gemcitabine in Treating Patients With Advanced Solid Tumors or Lymphoma | completed | Phase 1 | 30 | National Cancer Institute (NCI)NIH | 1 | Sep 30, 2013 | clinicaltrials |
| NCT00929903 | Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment | completed | Phase 1 | 55 | National Cancer Institute (NCI)NIH | 1 | Sep 30, 2013 | clinicaltrials |
| NCT00025597 | Combination Chemotherapy Followed by Surgery in Treating Infants With Newly Diagnosed Neuroblastoma. | completed | Phase 2 | — | European Infant Neuroblastoma Study Group - 1999OTHER | 11 | Sep 17, 2013 | clinicaltrials |
| NCT00025610 | Combination Chemotherapy in Treating Infants With Newly Diagnosed Neuroblastoma | completed | Phase 2 | — | European Infant Neuroblastoma Study Group - 1999OTHER | 11 | Sep 17, 2013 | clinicaltrials |
| NCT00025623 | Combination Chemotherapy Followed by Surgery in Treating Infants With Newly Diagnosed Neuroblastoma | completed | Phase 2 | — | European Infant Neuroblastoma Study Group - 1999OTHER | 11 | Sep 17, 2013 | clinicaltrials |
| NCT00025649 | Combination Chemotherapy Followed by Surgery and Peripheral Stem Cell or Bone Marrow Transplantation in Treating Infants With Newly Diagnosed Neuroblastoma | completed | Phase 2 | — | European Infant Neuroblastoma Study Group - 1999OTHER | 11 | Sep 17, 2013 | clinicaltrials |
| NCT00276679 | Temozolomide in Treating Young Patients With High-Risk Relapsed or Refractory Neuroblastoma | completed | Phase 2 | — | Children's Cancer and Leukaemia GroupOTHER | 3 | Sep 17, 2013 | clinicaltrials |
| NCT00953121 | Bevacizumab Plus Irinotecan Plus Carboplatin for Recurrent Malignant Glioma (MG) | completed | Phase 2 | 104 | Annick DesjardinsOTHER | 1 | Sep 16, 2013 | clinicaltrials |
| NCT00003203 | Carboplatin and Vincristine Plus Radiation Therapy Followed By Adjuvant Chemotherapy in Treating Young Patients With Newly Diagnosed CNS Embryonal Tumors | completed | Phase 2 | 168 | Children's Oncology GroupNETWORK | 3 | Aug 23, 2013 | clinicaltrials |
| NCT00305656 | AZD2171 in Treating Patients With Recurrent Glioblastoma Multiforme | completed | Phase 2 | 31 | National Cancer Institute (NCI)NIH | 1 | Aug 22, 2013 | clinicaltrials |
| NCT00612430 | Ph II Bevacizumab + Etoposide for Pts w Recurrent MG | completed | Phase 2 | 59 | Duke UniversityOTHER | 1 | Aug 12, 2013 | clinicaltrials |
| NCT00006461 | Combination Chemotherapy Followed by Second-Look Surgery and Radiation Therapy in Treating Children With Nonmetastatic Medulloblastoma or Primitive Neuroectodermal Tumor | completed | Phase 3 | 82 | Children's Oncology GroupNETWORK | 1 | Aug 9, 2013 | clinicaltrials |
| NCT00672243 | Ph II Erlotinib + Sirolimus for Pts w Recurrent Malignant Glioma Multiforme | completed | Phase 2 | 32 | Duke UniversityOTHER | 1 | Aug 7, 2013 | clinicaltrials |
| NCT00017225 | Chemotherapy and Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastoma | completed | Phase 2 | — | German Society for Pediatric Oncology and Hematology GPOH gGmbHOTHER | 3 | Aug 2, 2013 | clinicaltrials |
| NCT00039494 | Erlotinib and Temozolomide With Radiation Therapy in Treating Patients With Glioblastoma Multiforme or Other Brain Tumors | completed | Phase 2 | 171 | National Cancer Institute (NCI)NIH | 1 | Aug 2, 2013 | clinicaltrials |
Data updated 23 days agoSource updated Apr 29, 2014source: clinicaltrials