Cancer Family
Malignant Nervous System Neoplasm
CI-CAN-00000246Explore in graph →
953 active trials7 approved drugs131 evidence items
- NCIt
- C4788
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Cancer Family
CI-CAN-00000246Explore in graph →
Clinical trials
3,457 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (494)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00082758 | hu14.18-Interleukin-2 Fusion Protein in Treating Young Patients With Recurrent or Refractory Neuroblastoma | completed | Phase 2 | 39 | Children's Oncology GroupNETWORK | 2 | Feb 12, 2015 | clinicaltrials |
| NCT01853345 | iCAT for Recurrent/Refractory/HR Solid Tumors | completed | — | 101 | Dana-Farber Cancer InstituteOTHER | 1 | Feb 10, 2015 | clinicaltrials |
| NCT00723827 | Temodal (Temozolomide) Post Marketing Surveillance Protocol (Study P05557AM2) | completed | — | 682 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Jan 30, 2015 | clinicaltrials |
| NCT01386580 | An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma. | completed | Phase 1 / Phase 2 | 84 | BBB-Therapeutics B.V.INDUSTRY | 4 | Jan 22, 2015 | clinicaltrials |
| NCT00876499 | Fatigue, Sleep and Cytokines in Primary Brain Tumor (PBT) Patients | completed | — | 20 | M.D. Anderson Cancer CenterOTHER | 1 | Jan 9, 2015 | clinicaltrials |
| NCT00734682 | A Phase I Trial of Nanoliposomal CPT-11 (NL CPT-11) in Patients With Recurrent High-Grade Gliomas | completed | Phase 1 | 34 | University of California, San FranciscoOTHER | 1 | Jan 7, 2015 | clinicaltrials |
| NCT01131234 | Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors | completed | Phase 1 | 20 | National Cancer Institute (NCI)NIH | 1 | Dec 23, 2014 | clinicaltrials |
| NCT02227901 | Tipifarnib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | completed | Phase 1 | 19 | National Cancer Institute (NCI)NIH | 1 | Dec 23, 2014 | clinicaltrials |
| NCT01115491 | A Study of Bevacizumab and Extended Treatment of Temozolomide in Patients With Recurrent Glioblastoma Multiforme | completed | Phase 2 | 32 | Hoffmann-La RocheINDUSTRY | 1 | Dec 8, 2014 | clinicaltrials |
| NCT00024570 | Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma | completed | Phase 1 / Phase 2 | 60 | INSYS Therapeutics IncINDUSTRY | 1 | Nov 14, 2014 | clinicaltrials |
| NCT00331643 | Ixabepilone in Treating Young Patients With Refractory Solid Tumors | completed | Phase 2 | 120 | National Cancer Institute (NCI)NIH | 1 | Nov 14, 2014 | clinicaltrials |
| NCT00525525 | Study of Bevacizumab Plus Temodar and Tarceva in Patients With Glioblastoma or Gliosarcoma(AVF4120s) | completed | Phase 2 | 74 | University of California, San FranciscoOTHER | 1 | Nov 14, 2014 | clinicaltrials |
| NCT01158274 | RO4929097 and Capecitabine in Treating Patients With Refractory Solid Tumors | completed | Phase 1 | 30 | National Cancer Institute (NCI)NIH | 2 | Nov 7, 2014 | clinicaltrials |
| NCT00689221 | Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Methylated Gene Promoter Status(CENTRIC) | completed | Phase 3 | 545 | EMD SeronoINDUSTRY | 2 | Nov 4, 2014 | clinicaltrials |
| NCT00884416 | Sorafenib in Newly Diagnosed High Grade Glioma | completed | Phase 1 | 17 | University Hospital, GenevaOTHER | 1 | Nov 4, 2014 | clinicaltrials |
| NCT00576641 | Immunotherapy for Patients With Brain Stem Glioma and Glioblastoma | completed | Phase 1 | 22 | Cedars-Sinai Medical CenterOTHER | 1 | Oct 30, 2014 | clinicaltrials |
| NCT01770626 | A Pilot Study to Determine Nutrition Status in Glioblastoma Multiforme Patients(BEAM) | completed | Early Phase 1 | 40 | University of Alabama at BirminghamOTHER | 1 | Oct 28, 2014 | clinicaltrials |
| NCT00098865 | Thalidomide and Temozolomide in Relapsed or Progressive CNS Disease or Neuroblastoma | completed | Phase 2 | 15 | Dana-Farber Cancer InstituteOTHER | 1 | Oct 7, 2014 | clinicaltrials |
| NCT00528684 | Safety and Efficacy Study of REOLYSIN® in the Treatment of Recurrent Malignant Gliomas | completed | Phase 1 | 18 | Oncolytics BiotechINDUSTRY | 1 | Oct 2, 2014 | clinicaltrials |
| NCT00357500 | Etoposide, Cyclophosphamide, Thalidomide, Celecoxib, and Fenofibrate in Relapsed or Progressive Cancer | completed | Phase 2 | 101 | Dana-Farber Cancer InstituteOTHER | 1 | Oct 1, 2014 | clinicaltrials |
| NCT00311584 | Irinotecan and Temozolomide in Treating Young Patients With Recurrent Neuroblastoma | completed | Phase 2 | 59 | Children's Oncology GroupNETWORK | 3 | Sep 30, 2014 | clinicaltrials |
| NCT00960492 | Safety Study of XL184 (Cabozantinib) in Combination With Temozolomide and Radiation Therapy in the Initial Treatment of Adults With Glioblastoma | completed | Phase 1 | 26 | ExelixisINDUSTRY | 1 | Sep 22, 2014 | clinicaltrials |
| NCT00003107 | Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors | completed | Phase 1 | — | Indiana UniversityOTHER | 1 | Sep 10, 2014 | clinicaltrials |
| NCT01006044 | Efficacy & Safety of Autologous Dendritic Cell Vaccination in Glioblastoma Multiforme After Complete Surgical Resection | completed | Phase 2 | 26 | Clinica Universidad de Navarra, Universidad de NavarraOTHER | 1 | Sep 3, 2014 | clinicaltrials |
| NCT00003461 | Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors | completed | Phase 1 / Phase 2 | — | Duke UniversityOTHER | 1 | Aug 21, 2014 | clinicaltrials |
| NCT00293319 | 131 I-MIBG in Treating Patients With Refractory or Relapsed Neuroblastoma | completed | Phase 2 | 164 | University of California, San FranciscoOTHER | 1 | Aug 18, 2014 | clinicaltrials |
| NCT00616005 | Ph. II Treatment of Adults w Primary Malignant Glioma w Irinotecan + Temozolomide | completed | Phase 2 | 41 | Duke UniversityOTHER | 1 | Aug 18, 2014 | clinicaltrials |
| NCT01380782 | BIBF 1120 for Recurrent High-Grade Gliomas | completed | Phase 2 | 37 | Patrick Y. Wen, MDOTHER | 1 | Aug 18, 2014 | clinicaltrials |
| NCT00941460 | Comparison of Two Dosing Regimens of Temozolomide in Patients With Progressive or Recurrent Glioblastoma(DIRECTOR) | completed | Phase 2 | 105 | Prof. Dr. Wolfgang WickOTHER | 3 | Aug 15, 2014 | clinicaltrials |
| NCT00003750 | Biological Therapy in Treating Children With Refractory or Recurrent Neuroblastoma or Other Tumors | completed | Phase 1 | 28 | Children's Oncology GroupNETWORK | 3 | Aug 8, 2014 | clinicaltrials |
| NCT00003093 | Combination Chemotherapy in Treating Children With Neuroblastoma | completed | Phase 3 | 573 | Children's Oncology GroupNETWORK | 7 | Aug 1, 2014 | clinicaltrials |
| NCT00003234 | Vinorelbine in Treating Children With Recurrent or Refractory Cancers | completed | Phase 2 | 50 | Children's Oncology GroupNETWORK | 7 | Jul 28, 2014 | clinicaltrials |
| NCT00003846 | Radiation Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Primitive Neuroectodermal Tumors | completed | Phase 2 | 25 | Children's Oncology GroupNETWORK | 1 | Jul 28, 2014 | clinicaltrials |
| NCT00002740 | Combination Chemotherapy Plus Peripheral Stem Cell Transplantation Followed by Surgery and/or Radiation Therapy in Treating Young Patients With Advanced Neuroblastoma | completed | Phase 1 | 30 | Children's Oncology GroupNETWORK | 1 | Jul 24, 2014 | clinicaltrials |
| NCT00611728 | Ph I SU011248 + Irinotecan in Treatment of Pts w MG | completed | Phase 1 | 25 | Duke UniversityOTHER | 1 | Jul 21, 2014 | clinicaltrials |
| NCT00609999 | Ph I Dasatinib + Erlotinib in Recurrent MG | completed | Phase 1 | 47 | Duke UniversityOTHER | 1 | Jul 16, 2014 | clinicaltrials |
| NCT00612989 | Ph I 5-day Temozolomide + O6-BG in Treatment of Pts w Recurrent / Progressive GBM | completed | Phase 1 | 42 | Duke UniversityOTHER | 1 | Jul 16, 2014 | clinicaltrials |
| NCT00613093 | Ph. II Temozolomide + O6-BG in Treatment of Pts w Temozolomide-Resistant Malignant Glioma | completed | Phase 2 | 67 | Duke UniversityOTHER | 1 | Jul 9, 2014 | clinicaltrials |
| NCT00946335 | ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors | completed | Phase 1 | 31 | National Cancer Institute (NCI)NIH | 1 | Jul 9, 2014 | clinicaltrials |
| NCT00217412 | Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia | completed | Phase 1 | 60 | National Cancer Institute (NCI)NIH | 1 | Jun 17, 2014 | clinicaltrials |
| NCT00093613 | Sorafenib in Treating Patients With Recurrent or Progressive Malignant Glioma | completed | Phase 1 | 47 | National Cancer Institute (NCI)NIH | 1 | May 30, 2014 | clinicaltrials |
| NCT00650923 | Aflibercept, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme, Gliosarcoma, or Other Malignant Glioma | completed | Phase 1 | 61 | National Cancer Institute (NCI)NIH | 1 | May 30, 2014 | clinicaltrials |
| NCT00042991 | Gefitinib and Radiation Therapy in Treating Children With Newly Diagnosed Gliomas | completed | Phase 1 / Phase 2 | 69 | National Cancer Institute (NCI)NIH | 1 | May 28, 2014 | clinicaltrials |
| NCT00095940 | Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors | completed | Phase 1 / Phase 2 | 52 | National Cancer Institute (NCI)NIH | 1 | May 23, 2014 | clinicaltrials |
| NCT00238303 | Vorinostat in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme | completed | Phase 2 | 103 | National Cancer Institute (NCI)NIH | 1 | May 23, 2014 | clinicaltrials |
| NCT00245102 | Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma | completed | Phase 2 | 147 | National Cancer Institute (NCI)NIH | 1 | May 23, 2014 | clinicaltrials |
| NCT00641706 | Vorinostat and Bortezomib in Treating Patients With Progressive, Recurrent Glioblastoma Multiforme | completed | Phase 2 | 44 | National Cancer Institute (NCI)NIH | 1 | May 14, 2014 | clinicaltrials |
| NCT00492089 | Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer | completed | Phase 2 | 11 | National Cancer Institute (NCI)NIH | 1 | May 9, 2014 | clinicaltrials |
| NCT00597402 | Avastin in Combination With Radiation (XRT) & Temozolomide, Followed by Avastin, Temozolomide and Irinotecan for Glioblastoma (GBM) and Gliosarcomas | completed | Phase 2 | 125 | Duke UniversityOTHER | 1 | May 7, 2014 | clinicaltrials |
| NCT00575146 | Ketogenic Diet for Recurrent Glioblastoma(ERGO) | completed | Phase 1 | 20 | University Hospital TuebingenOTHER | 1 | May 2, 2014 | clinicaltrials |
Data updated 24 days agoSource updated Feb 12, 2015source: clinicaltrials