Subtype
Malignant Neoplasm of Unknown Primary
CI-CAN-00001150CUPExplore in graph →
4,163 active trials54 approved drugs532 evidence items
- NCIt
- C8566
- Other
- 1 more code
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Subtype
CI-CAN-00001150CUPExplore in graph →
Clinical trials
14,263 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (1,897)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05282433 | Surufatinib Alone or Combined With Anti-PD-1 mAb in the Treatment of Advanced Hepatocellular Carcinoma | unknown | Phase 2 | 45 | Zhongnan HospitalOTHER | 1 | Mar 16, 2022 | clinicaltrials |
| NCT03976973 | BromAc for Recurrent Peritoneal Mucinous Tumour or Pseudomyxoma Peritonei | unknown | Phase 2 | 62 | Mucpharm Pty LtdINDUSTRY | 0 | Mar 15, 2022 | clinicaltrials |
| NCT04390958 |
| Neoadjuvant Chemotherapy With Nab-paclitaxel Plus Cisplatin and Capecitabine for Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma |
| unknown |
| Phase 2 |
| 70 |
| Chinese Academy of Medical SciencesOTHER |
| 1 |
| Mar 15, 2022 |
| clinicaltrials |
| NCT05279521 | The Effect of Interventional Pulmonary Rehabilitation Exercise With Advanced Lung Cancer. | unknown | N/A | 104 | National Taiwan University HospitalOTHER | 0 | Mar 15, 2022 | clinicaltrials |
| NCT05277675 | Radiofrequency Ablation Plus Systematic Neoadjuvant Therapy for Recurrent Hepatocellular Carcinoma (RANT Study)(RANT) | unknown | N/A | 160 | Southwest Hospital, ChinaOTHER | 1 | Mar 14, 2022 | clinicaltrials |
| NCT05278195 | Assessing the Prognosis of TACE in Combination With PD-1/PD-L1 Inhibitors and Molecular Target Therapies for HCC by Using Clinical and Imaging Biomarkers(CHANCEsub) | unknown | — | 300 | Zhongda HospitalOTHER | 1 | Mar 14, 2022 | clinicaltrials |
| NCT05275985 | 68Ga-FAPI PET/CT in Pancreatic Ductal Carcinoma | unknown | N/A | 80 | Peking Union Medical College HospitalOTHER | 1 | Mar 11, 2022 | clinicaltrials |
| NCT05075122 | Tolerability and Efficacy of UV1 Vaccine in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Planned for First-line Treatment With Pembrolizumab(FOCUS) | unknown | Phase 2 | 75 | Martin-Luther-Universität Halle-WittenbergOTHER | 1 | Mar 9, 2022 | clinicaltrials |
| NCT05270642 | Plan for Microwave Thermal Field | unknown | N/A | 5 | Chinese PLA General HospitalOTHER | 1 | Mar 8, 2022 | clinicaltrials |
| NCT05270889 | Study to Evaluate the Safety and Efficacy of Tislelizumab in Combination With Zanidatamab as a 2nd Line in HER2-Positive Advanced Gastric Cancer in K-Umbrella Trial | unknown | Phase 2 | 50 | Yonsei UniversityOTHER | 1 | Mar 8, 2022 | clinicaltrials |
| NCT05268952 | A Study to Evaluate the Value of Circulating Tumour DNA in Follow-up of Patients With an Advanced Gastroenteropancreatic or Lung Neuroendocrine Tumour Under Everolimus +- SSA Treatment (Liquid-NET 2.0) | unknown | N/A | 100 | University Hospital, AntwerpOTHER | 2 | Mar 7, 2022 | clinicaltrials |
| NCT03917966 | The Phase II Trial of SHR-1210 Combined With Preoperative Chemotherapy or Apatinib for Locally Advanced ESCC | unknown | Phase 2 | 80 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Mar 4, 2022 | clinicaltrials |
| NCT05265962 | Decitabine Plus Penpulimab as Second-line Therapy for Advanced ESCC Treated With PD-1 Blockade | unknown | Phase 2 | 85 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 0 | Mar 4, 2022 | clinicaltrials |
| NCT05267353 | Develop and Test the 'Multi-Faced Continuous Exercise Program' in Operable Head and Neck Cancer Patients | unknown | N/A | 390 | National Taiwan University HospitalOTHER | 0 | Mar 4, 2022 | clinicaltrials |
| NCT03322280 | TACE Combined With Iodine-125 Seeds Implantation for HCC | unknown | N/A | 270 | Second Affiliated Hospital of Guangzhou Medical UniversityOTHER | 1 | Mar 3, 2022 | clinicaltrials |
| NCT05262413 | A Study of QL1706 Plus Lenvatinib in Subjects With Advanced Renal Cell Carcinoma(RCC) | unknown | Phase 1 / Phase 2 | 60 | Qilu Pharmaceutical Co., Ltd.INDUSTRY | 0 | Mar 2, 2022 | clinicaltrials |
| NCT03145961 | A Trial Using ctDNA Blood Tests to Detect Cancer Cells After Standard Treatment to Trigger Additional Treatment in Early Stage Triple Negative Breast Cancer Patients(c-TRAK-TN) | unknown | Phase 2 | 208 | Institute of Cancer Research, United KingdomOTHER | 1 | Feb 24, 2022 | clinicaltrials |
| NCT04787328 | A Study of HA121-28 Tablets in Patients With Medullary Thyroid Carcinoma (MTC) | unknown | Phase 2 | 30 | CSPC ZhongQi Pharmaceutical Technology Co., Ltd.INDUSTRY | 1 | Feb 23, 2022 | clinicaltrials |
| NCT05150509 | Association of Salivary Amino Acid Level With OSCC Identified By Liquid Chromatography Mass Spectroscopy(OSCC) | unknown | — | 110 | DR. MALA KHANOTHER_GOV | 1 | Feb 22, 2022 | clinicaltrials |
| NCT05245994 | An Open Label, Multicenter Phase 2 Study of Durvalumab (MEDI4736) + Olaparib as Maintenance Therapy in Chinese | unknown | Phase 2 | 60 | Li Zhang, MDOTHER | 1 | Feb 18, 2022 | clinicaltrials |
| NCT05246228 | Immune System Modulation and Outcome in High-risk cSCC Treated With Surgery and Radiotherapy(HR-cSCC) | unknown | — | 42 | Azienda Socio Sanitaria Territoriale degli Spedali Civili di BresciaOTHER | 0 | Feb 18, 2022 | clinicaltrials |
| NCT05247476 | Type 2 Deiodinase Gene Polymorphism and the Treatment of Hypothyroidism Caused by Thyroidectomy in Thyroid Cancer Patients. | unknown | Phase 4 | 50 | Zhongshan Hospital Xiamen UniversityOTHER | 1 | Feb 18, 2022 | clinicaltrials |
| NCT03221400 | PEN-866 in Patients With Advanced Solid Malignancies | unknown | Phase 1 / Phase 2 | 340 | Tarveda TherapeuticsINDUSTRY | 1 | Feb 17, 2022 | clinicaltrials |
| NCT03177239 | Phase II Sequential Treatment Trial of Single Agent Nivolumab, Then Combination Ipilimumab + Nivolumab in Metastatic or Unresectable Non-Clear Cell Renal Cell Carcinoma (ANZUP1602)(UNISoN) | unknown | Phase 2 | 85 | Australian and New Zealand Urogenital and Prostate Cancer Trials GroupOTHER | 1 | Feb 16, 2022 | clinicaltrials |
| NCT05242237 | Prognostic Value of Liver Cancer CTCs Isolated by a Novel Microfluidic Platform | unknown | — | 300 | The Second Affiliated Hospital of Chongqing Medical UniversityOTHER | 1 | Feb 16, 2022 | clinicaltrials |
| NCT05242757 | Clinical Study of MAK Immune Cells in the Treatment of PHC | unknown | N/A | 12 | Zhongnan HospitalOTHER | 1 | Feb 16, 2022 | clinicaltrials |
| NCT05240404 | Adjuvant Immunotherapy With Toripalimab Following Curative-intent Ablation for Recurrent Hepatocarcinoma | unknown | Phase 2 | 116 | Xiangya Hospital of Central South UniversityOTHER | 1 | Feb 15, 2022 | clinicaltrials |
| NCT05240690 | Umbilical Cord Blood Derived MAK Immune Cells Combined With Standard Second-Line Treatments for Hepatobiliary and Pancreatic Malignancies | unknown | Phase 1 | 27 | Zhou FuxiangOTHER | 1 | Feb 15, 2022 | clinicaltrials |
| NCT05241132 | Tislelizumab Combined With Chemotherapy in the Treatment of Bone Metastases of Unknown Primary | unknown | Phase 2 | 27 | Wei XuOTHER | 1 | Feb 15, 2022 | clinicaltrials |
| NCT02009176 | Laparoscope Anatomical and Aon-anatomical Hepatectomy | unknown | N/A | 110 | Shuguo Zheng, MDOTHER | 1 | Feb 11, 2022 | clinicaltrials |
| NCT03605706 | A Trial of SHR-1210 (an Anti-PD-1 Inhibitor) in Combination With FOLFOX4 in Subjects With Advanced HCC Who Have Never Received Prior Systemic Treatment. | unknown | Phase 3 | 396 | Jiangsu HengRui Medicine Co., Ltd.INDUSTRY | 1 | Feb 10, 2022 | clinicaltrials |
| NCT05118451 | A Multicenter RCT Study of 3DV Technology in the Diagnosis and Treatment of PLC | unknown | N/A | 420 | Zhujiang HospitalOTHER | 1 | Feb 10, 2022 | clinicaltrials |
| NCT05233358 | HAIC Combined With Second-line "Target Immunity" for HCC With TACE Standard Treatment Low Response or Failure | unknown | N/A | 176 | The Central Hospital of Lishui CityOTHER | 0 | Feb 10, 2022 | clinicaltrials |
| NCT05233540 | Circulating Biomarkers in Patients With Anal Cancer Treated With Induction Chemotherapy | unknown | — | 60 | Aarhus University HospitalOTHER | 1 | Feb 10, 2022 | clinicaltrials |
| NCT04177797 | Toripalimab With Neoadjuvant Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 20 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Feb 9, 2022 | clinicaltrials |
| NCT05201729 | Influence Factors of PD-1 Therapeutic Efficacy in Advanced Pancreatic Cancer | unknown | — | 30 | Ruijin HospitalOTHER | 1 | Feb 8, 2022 | clinicaltrials |
| NCT02446704 | Study of Olaparib and Temozolomide in Patients With Recurrent Small Cell Lung Cancer Following Failure of Prior Chemotherapy | unknown | Phase 1 / Phase 2 | 66 | Zofia PiotrowskaOTHER | 1 | Feb 7, 2022 | clinicaltrials |
| NCT04740996 | Study of Pembrolizumab in the First Line Therapy for R/M HNSCC in China | unknown | — | 30 | Shi YuankaiUNKNOWN | 1 | Feb 7, 2022 | clinicaltrials |
| NCT05213637 | Expanded Activated Lymphocytes (EAL) as Adjuvant Therapy in Patients With HCC at High Risk of Recurrence After Radical Resection | unknown | Phase 2 | 430 | Chinese PLA General HospitalOTHER | 1 | Feb 7, 2022 | clinicaltrials |
| NCT05224024 | Retzius-sparing Technique in Robotic-assisted Radical Prostatectomy | unknown | N/A | 80 | Ankara UniversityOTHER | 1 | Feb 4, 2022 | clinicaltrials |
| NCT04617821 | AG vs mFOLFIRINOX as Neoadjuvant Therapy for Borderline Reseactable and Locally Advanced Pancreatic Cancer | unknown | Phase 3 | 300 | Fudan UniversityOTHER | 1 | Jan 28, 2022 | clinicaltrials |
| NCT04233840 | P1101 and Anti-PD1 for After Curative Surgery of Hepatitis B-related Hepatocellular Carcinoma | unknown | Phase 1 / Phase 2 | 72 | National Taiwan University HospitalOTHER | 1 | Jan 27, 2022 | clinicaltrials |
| NCT05113290 | Effect and Safety of Recombinant Human Adenovirus Type 5 in Advanced HCC With Stable Disease After Sorafenib Treatment | unknown | Phase 4 | 66 | First Affiliated Hospital Xi'an Jiaotong UniversityOTHER | 1 | Jan 27, 2022 | clinicaltrials |
| NCT05162898 | Radiofrequency Ablation Combined With Toripalimab and Lenvatinib in the Treatment of Short-term Recurrent Hepatocellular Carcinoma. | unknown | N/A | 90 | Henan Cancer HospitalOTHER_GOV | 0 | Jan 27, 2022 | clinicaltrials |
| NCT05210348 | Clinical Evaluation of Detection of High Risk HPV in Urine(Urine-hrHPV) | unknown | — | 1,000 | Peking University People's HospitalOTHER | 1 | Jan 27, 2022 | clinicaltrials |
| NCT03067493 | RFA or Surgical Resection Combined With Neo-MASCT for Primary HCC: a Phase II Trial(RAMEC) | unknown | Phase 2 | 98 | Sun Yat-sen UniversityOTHER | 1 | Jan 26, 2022 | clinicaltrials |
| NCT05207904 | Tislelizumab Plus Chemotherapy as First-Line Treatment for Advanced Squamous NSCLC With Brain Metastases | unknown | Phase 2 | 41 | Sun Yat-sen UniversityOTHER | 1 | Jan 26, 2022 | clinicaltrials |
| NCT05202015 | Non-invasive MRI Subclassification of Heptocellular Carcinoma - HepCaSt-Study(HepCaSt) | unknown | — | 150 | Charite University, Berlin, GermanyOTHER | 1 | Jan 21, 2022 | clinicaltrials |
| NCT05202275 | The Optimization of Antiemetic Regimen for C-RINV in LA-HNSCCs | unknown | Phase 2 | 43 | Chinese Academy of Medical SciencesOTHER | 1 | Jan 21, 2022 | clinicaltrials |
| NCT05199649 | Correlation Between the Efficacy of Neoadjuvant Chemotherapy Combined With Immunotherapy of Operable Thoracic Esophageal Squamous Cell Carcinoma and the Metabolites of Intestinal Flora | unknown | N/A | 30 | The First Affiliated Hospital of Soochow UniversityOTHER | 1 | Jan 20, 2022 | clinicaltrials |
Data updated 24 days agoSource updated Mar 16, 2022source: clinicaltrials