Subtype
Malignant Neck Neoplasm
CI-CAN-00001148Explore in graph →
607 active trials11 approved drugs67 evidence items
- NCIt
- C4940
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Subtype
CI-CAN-00001148Explore in graph →
Clinical trials
2,145 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (181)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03360890 | Pembrolizumab With Chemotherapy for Poorly Chemo-responsive Thyroid and Salivary Gland Tumors(iPRIME) | active not recruiting | Phase 2 | 46 | University of ChicagoOTHER | 1 | Mar 13, 2026 | clinicaltrials |
| NCT06030440 | De-Intensification of Postoperative Radiotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck(DIREKHT2) | recruiting | Phase 2 / Phase 3 | 508 | University of Erlangen-Nürnberg Medical SchoolOTHER |
| 1 |
| Mar 13, 2026 |
| clinicaltrials |
| NCT03753919 | Durvalumab Plus Tremelimumab for the Treatment of Patients With Progressive, Refractory Advanced Thyroid Carcinoma -The DUTHY Trial(DUTHY) | terminated | Phase 2 | 79 | Grupo Espanol de Tumores NeuroendocrinosOTHER | 1 | Mar 11, 2026 | clinicaltrials |
| NCT04696744 | Prospective Study for the Prognostic and Predictive Role of Circulating Tumor Cells in Patients With Oropharyngeal Squamous Cell Carcinoma: CTCO (Circulating Tumor Cells in the Oropharynx)(CTCO) | completed | — | 12 | Hospices Civils de LyonOTHER | 1 | Mar 11, 2026 | clinicaltrials |
| NCT00939627 | Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent Cetuximab | completed | Phase 2 | 55 | National Cancer Institute (NCI)NIH | 1 | Mar 10, 2026 | clinicaltrials |
| NCT04742608 | Development of Liquid Biopsy Technologies for Noninvasive Cancer Diagnostics in Patients With Suspicious Thyroid Nodules or Thyroid Cancer | recruiting | — | 250 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Mar 10, 2026 | clinicaltrials |
| NCT04030455 | Cisplatin, Docetaxel, and Pembrolizumab in Treating Patients With Stage II-III Laryngeal Cancer | active not recruiting | Phase 2 | 28 | M.D. Anderson Cancer CenterOTHER | 1 | Mar 9, 2026 | clinicaltrials |
| NCT07412314 | Proton Therapy for Recurrent Nasopharyngeal Carcinoma | recruiting | N/A | 52 | Guangzhou Concord Cancer CenterOTHER | 1 | Mar 9, 2026 | clinicaltrials |
| NCT07457099 | Impact of Postoperative Radiotherapy Versus PD-1 Inhibitor Maintenance on Survival in Resectable Locally Advanced Oral and Oropharyngeal Squamous Cell Carcinoma | not yet recruiting | — | 85 | Zhujiang HospitalOTHER | 1 | Mar 9, 2026 | clinicaltrials |
| NCT03570021 | ESTIMation of the ABiLity of Prophylactic Central Compartment Neck Dissection to Modify Outcomes in Low-risk Differentiated Thyroid Cancer(ESTIMABL3) | active not recruiting | Phase 3 | 352 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 3 | Mar 6, 2026 | clinicaltrials |
| NCT06239727 | Reduced-dose Radiotherapy for Stage III Nasopharyngeal Carcinoma Based on the Treatment Response | recruiting | Phase 3 | 593 | Sun Yat-sen UniversityOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT02597426 | Nasopharyngeal Carcinoma Post IMRT | active not recruiting | — | 108 | University Health Network, TorontoOTHER | 1 | Mar 4, 2026 | clinicaltrials |
| NCT05721222 | Trial of PRO1160 (GEN1160) in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) (PRO1160-001) | terminated | Phase 1 / Phase 2 | 42 | GenmabINDUSTRY | 2 | Mar 4, 2026 | clinicaltrials |
| NCT06868433 | TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer | recruiting | Phase 1 | 40 | Emory UniversityOTHER | 1 | Mar 4, 2026 | clinicaltrials |
| NCT07327216 | Sapylin Versus Dexamethasone Inhalation for CCRT-Induced Oral Mucositis in Nasopharyngeal Carcinoma | recruiting | Phase 3 | 180 | Affiliated Hospital of Guangdong Medical UniversityOTHER | 1 | Mar 4, 2026 | clinicaltrials |
| NCT05389306 | Combining MRI and CEUS to Diagnose Small Cervical Lymph Node Metastases in NPC Patients(NPC-LN) | completed | N/A | 348 | Sun Yat-sen UniversityOTHER | 1 | Mar 3, 2026 | clinicaltrials |
| NCT06524167 | RW Study of Adjuvant Radiotherapy in Locally Advanced Thyroid Cancer | recruiting | — | 80 | Fudan UniversityOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT06554652 | Selective Neck Dissection Versus Modified Neck Dissection in PTC | recruiting | Phase 3 | 250 | Fudan UniversityOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT06558981 | Adjuvant Radiotherapy in High Risk Locally Advanced DTC | recruiting | Phase 3 | 124 | Fudan UniversityOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT07044635 | Shortened Course of Radiation Therapy After Trans-oral Robotic Surgery in Patients With HPV-Mediated Oropharyngeal Squamous Cell Carcinoma.(RAD RAPTORS) | recruiting | Phase 2 | 42 | University of UtahOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT07193186 | Anlotinib and Benmelstobart in DTC | not yet recruiting | Phase 2 | 23 | Fudan UniversityOTHER | 0 | Feb 27, 2026 | clinicaltrials |
| NCT07436455 | F-18 Tetrafluoroborate PET/CT in Differentiated Thyroid Cancer(NISDETECT) | recruiting | N/A | 50 | Ankara UniversityOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT07438847 | 177Lu-CTR-FAPI for the Treatment of Thyroid Cancer | recruiting | Phase 1 | 12 | SHAOYAN LIUOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT05261750 | Autologous Dendritic Cells and Allogenic Dendritic Secretomes for Patients With Advanced Nasopharyngeal Cancer | active not recruiting | Phase 1 / Phase 2 | 15 | PT. Prodia Stem Cell IndonesiaINDUSTRY | 1 | Feb 25, 2026 | clinicaltrials |
| NCT07433283 | Carbon Nanoparticle-Loaded Iron in the Treatment of Advanced Solid Tumor | recruiting | Phase 1 / Phase 2 | 54 | Sichuan Enray Pharmaceutical Sciences CompanyOTHER | 1 | Feb 25, 2026 | clinicaltrials |
| NCT05837221 | Microbiome in Head and Neck Squamous Cell Carcinoma | recruiting | — | 60 | University of Colorado, DenverOTHER | 1 | Feb 24, 2026 | clinicaltrials |
| NCT03174275 | Carboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and Neck Squamous Cell Carcinoma | active not recruiting | Phase 2 | 39 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Feb 23, 2026 | clinicaltrials |
| NCT04713449 | Enhancing Self Care Among Oral Cancer Survivors: The Empowered Survival Trial | active not recruiting | N/A | 643 | Rutgers, The State University of New JerseyOTHER | 1 | Feb 23, 2026 | clinicaltrials |
| NCT05229341 | Evaluation of DNA Methylation Signatures for the Diagnosis and Management of Thyroid Nodules | recruiting | N/A | 1,450 | City of Hope Medical CenterOTHER | 1 | Feb 23, 2026 | clinicaltrials |
| NCT07428148 | Lattice-Based Radiotherapy and Chemoimmunotherapy for Oropharyngeal Squamous Cell Carcinoma | not yet recruiting | Phase 1 / Phase 2 | 60 | NYU Langone HealthOTHER | 1 | Feb 23, 2026 | clinicaltrials |
| NCT03656133 | Use of a Proliferation Saturation Index to Determine Personalized Radiotherapy for HPV + Oropharyngeal Cancers | completed | N/A | 55 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Feb 20, 2026 | clinicaltrials |
| NCT06600295 | Oncology, Undernutrition and Sensoriality: Links, Mechanisms and Levers for Action(ONDES) | recruiting | — | 306 | Centre Hospitalier Universitaire DijonOTHER | 1 | Feb 19, 2026 | clinicaltrials |
| NCT07063212 | A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC) | recruiting | Phase 2 | 40 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 19, 2026 | clinicaltrials |
| NCT07419932 | Response to Neoadjuvant Treatment in Locally Advanced Thyroid Cancer(NeoLATC) | recruiting | — | 120 | Fujian Medical UniversityOTHER | 1 | Feb 19, 2026 | clinicaltrials |
| NCT06059261 | Envafolimab Combined With Chemoradiotherapy and Recombinant Human Endostatin for LA-NPC. | recruiting | Phase 2 | 30 | Chongqing University Cancer HospitalOTHER | 1 | Feb 18, 2026 | clinicaltrials |
| NCT03822897 | De-Escalation Radiotherapy in Patients With Low-Risk HPV-Related Oropharyngeal Squamous Cell Carcinoma(EVADER) | active not recruiting | Phase 2 | 103 | Canadian Cancer Trials GroupNETWORK | 1 | Feb 17, 2026 | clinicaltrials |
| NCT06073223 | Intervention to Decrease Overtreatment of Patients With Low-risk Thyroid Cancer | completed | N/A | 50 | University of Michigan Rogel Cancer CenterOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT07407205 | Tumor Mutational Burden, Liquid Biopsy, Angiogenic Factors and DCE-MRI Perfusion in HPV-Negative Oropharyngeal Cancer | active not recruiting | N/A | 30 | Institute of Oncology LjubljanaOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT07033091 | Prevalence of Human Papillomavirus (HPV) in a Healthy Population: A Feasibility Study of Oropharyngeal Cancer Screening | recruiting | N/A | 20,000 | The Institute of Molecular and Translational Medicine, Czech RepublicOTHER | 1 | Feb 13, 2026 | clinicaltrials |
| NCT07381699 | MRG003 Combined With Immunotherapy in Recurrent/Metastatic Nasopharyngeal Carcinoma: A Phase II Clinical Trial | not yet recruiting | Phase 2 | 30 | West China HospitalOTHER | 0 | Feb 13, 2026 | clinicaltrials |
| NCT07410637 | Impact of Thyroid Hormones on Human Glucose and Energy Metabolism | recruiting | N/A | 60 | University of UlmOTHER | 1 | Feb 13, 2026 | clinicaltrials |
| NCT03993353 | Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer | completed | Phase 2 | 7 | University of California, San DiegoOTHER | 1 | Feb 12, 2026 | clinicaltrials |
| NCT04151134 | Evaluation of Tongue Base MucOsectomy & Step sErial Sectioning(MOSES) | active not recruiting | — | 100 | Royal Marsden NHS Foundation TrustOTHER | 1 | Feb 12, 2026 | clinicaltrials |
| NCT05774561 | Role of Liquid Biopsies in HPV-associated Cancer Treatment Monitoring | recruiting | — | 480 | The Institute of Molecular and Translational Medicine, Czech RepublicOTHER | 1 | Feb 12, 2026 | clinicaltrials |
| NCT07405320 | A Brief Video Intervention to Improve Patient Outcomes Following Radioiodine Treatment | not yet recruiting | N/A | 80 | University of Auckland, New ZealandOTHER | 0 | Feb 12, 2026 | clinicaltrials |
| NCT02143726 | Sorafenib Tosylate With or Without Everolimus in Treating Patients With Advanced, Radioactive Iodine Refractory Hurthle Cell Thyroid Cancer | active not recruiting | Phase 2 | 35 | Alliance for Clinical Trials in OncologyOTHER | 1 | Feb 11, 2026 | clinicaltrials |
| NCT06636734 | Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial | recruiting | Phase 2 | 28 | Emory UniversityOTHER | 1 | Feb 11, 2026 | clinicaltrials |
| NCT07402538 | Surgery With or Without Neoadjuvant Treatment of SBRT Plus Chemoimmunotherapy in Resectable Locally Advanced Oral and HPV-unrelated Oropharyngeal Squamous Cell Carcinoma | not yet recruiting | Phase 3 | 184 | Sun Yat-sen UniversityOTHER | 1 | Feb 11, 2026 | clinicaltrials |
| NCT01473784 | Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck | recruiting | N/A | 600 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT01932697 | Radiation Therapy and Docetaxel in Treating Patients With HPV-Related Oropharyngeal Cancer | completed | Phase 2 | 81 | Mayo ClinicOTHER | 1 | Feb 10, 2026 | clinicaltrials |
Data updated 23 days agoSource updated Mar 13, 2026source: clinicaltrials