Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,502 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02078726 | Glucagon Use in Colonoscopies | completed | Phase 4 | 100 | University of California, San FranciscoOTHER | 1 | Jul 3, 2025 | clinicaltrials |
| NCT06314971 | Predicting Local and Distant Recurrence in T1 Colorectal Cancer(T1CR) | completed | — | 138 | City of Hope Medical CenterOTHER | 3 | Jul 3, 2025 | clinicaltrials |
| NCT07048847 | The Effect of Aerobic Exercise on Selective Biomarkers of Patients With Cancer | completed | — | 32 | Izmir Bakircay UniversityOTHER | 1 | Jul 3, 2025 | clinicaltrials |
| NCT02821793 | Expectations and Priorities of Elderly Patients for a First Medical Treatment for Cancer(PRIORITY) | completed | — | 346 | Institut BergoniéOTHER | 1 | Jul 1, 2025 | clinicaltrials |
| NCT03442569 | PhII Trial Panitumumab, Nivolumab, Ipilimumab in Kras/Nras/BRAF Wild-type MSS Refractory mCRC | completed | Phase 2 | 56 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Jul 1, 2025 | clinicaltrials |
| NCT03630354 | EXERCISING TOGETHER for Couples Coping With Cancer | completed | N/A | 496 | OHSU Knight Cancer InstituteOTHER | 1 | Jul 1, 2025 | clinicaltrials |
| NCT03186326 | Standard Chemotherapy vs Immunotherapie in 2nd Line Treatment of MSI Colorectal Mestastatic Cancer(SAMCO) | completed | Phase 2 | 132 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Jun 29, 2025 | clinicaltrials |
| NCT03584711 | FOLFOX + Panitumumab According to a "Stop and go" Strategy With a Reintroduction Loop After Progression on Fluoropyrimidine as Maintenance Treatment, as the First Line in Patients With Metastatic Colorectal Adenocarcinoma Without a RAS Mutation(OPTIPRIME) | completed | Phase 2 | 118 | Federation Francophone de Cancerologie DigestiveOTHER | 2 | Jun 29, 2025 | clinicaltrials |
| NCT03789162 | Blood and Stool Sample Collection in Subjects With a Diagnosis of Colorectal Cancer or Colorectal Lesion: Act Fast | completed | — | 850 | Exact Sciences CorporationINDUSTRY | 2 | Jun 29, 2025 | clinicaltrials |
| NCT03519295 | A Study of mDCF in Combination or Not With Atezolizumab in Advanced Squamous Cell Anal Carcinoma(SCARCE) | completed | Phase 2 | 97 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Jun 27, 2025 | clinicaltrials |
| NCT06414304 | Dynamics of MSI and Genomic Profile of Colorectal Cancer In the Course of Immune Checkpoint Inhibitor Therapy(BLOOMSI) | completed | — | 30 | OncoAtlas LLCINDUSTRY | 1 | Jun 27, 2025 | clinicaltrials |
| NCT05468827 | ICG Fluorescence Guided Lymph Node Mapping for Determination of Bowel Resection Margins in Colon Cancer(ISCAPE) | completed | N/A | 108 | N.N. Petrov National Medical Research Center of OncologyOTHER | 1 | Jun 26, 2025 | clinicaltrials |
| NCT02824484 | A Guided Written Disclosure Intervention to Promote Post-traumatic Growth in Cancer Patients GUIDED WRITTEN DISCLOSURE | completed | N/A | 250 | Azienda USL Reggio Emilia - IRCCSOTHER_GOV | 1 | Jun 25, 2025 | clinicaltrials |
| NCT04697394 | CITRuS Stage 1; Feasibility(CITRuS1) | completed | — | 380 | Royal Surrey County Hospital NHS Foundation TrustOTHER | 1 | Jun 25, 2025 | clinicaltrials |
| NCT04500171 | Colorectal Cancer Screening Assessment Study | completed | N/A | 264 | University of HawaiiOTHER | 1 | Jun 24, 2025 | clinicaltrials |
| NCT00873275 | Ursodiol, Combination Chemotherapy, and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer | completed | Phase 1 | 11 | City of Hope Medical CenterOTHER | 1 | Jun 22, 2025 | clinicaltrials |
| NCT03267524 | Walking for Recovery From Surgery in Improving Quality of Life in Older Adults With Lung or Gastrointestinal Cancer and Their Family Caregivers | completed | N/A | 87 | City of Hope Medical CenterOTHER | 1 | Jun 22, 2025 | clinicaltrials |
| NCT02368886 | Lower or Standard Dose Regorafenib in Treating Patients With Refractory Metastatic Colorectal Cancer | completed | Phase 2 | 123 | Academic and Community Cancer Research UnitedOTHER | 1 | Jun 18, 2025 | clinicaltrials |
| NCT07026955 | Colorectal Cancer in Young Adults: Study of Incidence, Survival, and Prognostic Factors in Tarragona, Spain(CCR50) | completed | — | 59 | HJ23INDUSTRY | 1 | Jun 18, 2025 | clinicaltrials |
| NCT04625803 | Neoadjuvant Therapy for Locally Advanced Colon Cancer | completed | Phase 2 | 64 | Zhejiang UniversityOTHER | 1 | Jun 17, 2025 | clinicaltrials |
| NCT03642067 | Study of Nivolumab and Relatlimab in Patients With Microsatellite Stable (MSS) Advanced Colorectal Cancer | completed | Phase 2 | 59 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Jun 15, 2025 | clinicaltrials |
| NCT05788484 | A Study of CDX-585 in Patients With Advanced Malignancies | completed | Phase 1 | 20 | Celldex TherapeuticsINDUSTRY | 1 | Jun 15, 2025 | clinicaltrials |
| NCT07021378 | Tolerance to Immunomodulatory Nutritional Therapy in Oncology Patients Undergoing Chemotherapy and Radiotherapy(NESTLE) | completed | N/A | 16 | D'Or Institute for Research and EducationOTHER | 1 | Jun 15, 2025 | clinicaltrials |
| NCT01804790 | Efficacy of Neoadjuvant Folfirinox Regimen in Patients With Resectable Locally Advanced Rectal Cancer(Néofirinox) | completed | Phase 3 | 461 | UNICANCEROTHER | 1 | Jun 12, 2025 | clinicaltrials |
| NCT07012538 | RASi for Preventing Postoperative Recurrence of Stage II/III Colon Cancer(RAIPC) | completed | — | 2,640 | Fudan UniversityOTHER | 1 | Jun 10, 2025 | clinicaltrials |
| NCT04554836 | MoLiMoR - A Study With FOLFIRI-based First-line Therapy With or Without Intermittent Cetuximab | completed | Phase 2 | 6 | TheraOpOTHER | 1 | Jun 8, 2025 | clinicaltrials |
| NCT04616196 | Study of NKTR 255 in Combination With Cetuximab in Solid Tumors | completed | Phase 1 / Phase 2 | 25 | Nektar TherapeuticsINDUSTRY | 1 | Jun 8, 2025 | clinicaltrials |
| NCT05405530 | Nasal Mask Kit in Gastrointestinal Endoscopy(NASO) | completed | N/A | 1,204 | RenJi HospitalOTHER | 1 | Jun 5, 2025 | clinicaltrials |
| NCT01493206 | A Prospective Single Arm Study of Intraoperative Radiotherapy for Locally Advanced or Recurrent Rectal Cancer | completed | Phase 2 | 32 | Peter MacCallum Cancer Centre, AustraliaOTHER | 1 | May 31, 2025 | clinicaltrials |
| NCT00324415 | Combined Modality Therapy for Patients With With HIV and Stage I, Stage II, or Stage III Anal Cancer | completed | Phase 2 | 45 | AIDS Malignancy ConsortiumNETWORK | 1 | May 30, 2025 | clinicaltrials |
| NCT04068896 | Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy | completed | Phase 1 / Phase 2 | 89 | NGM Biopharmaceuticals, IncINDUSTRY | 1 | May 29, 2025 | clinicaltrials |
| NCT06242197 | Comparing the Effectiveness of Written Vs Verbal Advice for First Degree Relatives of Colorectal Cancer Patients | completed | N/A | 180 | Ramathibodi HospitalOTHER | 1 | May 29, 2025 | clinicaltrials |
| NCT05667181 | The Application Value of da Vinci Linear Cutting Stapler SureForm in Robotic Anus Preserving Surgery for Rectal Cancer | completed | N/A | 276 | Nanchang UniversityOTHER | 1 | May 28, 2025 | clinicaltrials |
| NCT05801965 | A Digital Therapeutic Solution for Cancer Patients | completed | N/A | 48 | Sidekick HealthINDUSTRY | 1 | May 25, 2025 | clinicaltrials |
| NCT03206151 | CMAB009 Combined With FOLFIRI First-line Treatment in Patients With RAS/BRAF Wild-type, Metastatic Colorectal Cancer | completed | Phase 3 | 520 | Taizhou Mabtech Pharmaceutical Co.,LtdINDUSTRY | 1 | May 23, 2025 | clinicaltrials |
| NCT06804876 | COMBO Endoscopy Oropharyngeal Airway in Sedated Gastrointestinal Endoscopy for Obese Patients | completed | Phase 2 | 107 | Zhejiang UniversityOTHER | 1 | May 21, 2025 | clinicaltrials |
| NCT04121286 | A Study of JAB-3312 in Adult Patients With Advanced Solid Tumors in China | completed | Phase 1 | 17 | Allist Pharmaceuticals, Inc.INDUSTRY | 1 | May 20, 2025 | clinicaltrials |
| NCT02138617 | Genotype-Directed Study Of Irinotecan Dosing In FOLFIRI + BevacizumabTreated Metastatic Colorectal Cancer | completed | Phase 2 | 100 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | May 18, 2025 | clinicaltrials |
| NCT06978595 | Primary Colorectal Signet Ring Cell Carcinoma and the Risk of Multiple Primary Gastrointestinal Malignancies | completed | — | 8,171 | asmaa salama ibrahimOTHER | 1 | May 18, 2025 | clinicaltrials |
| NCT04449679 | Real-Time Monitoring of Chemotherapy Side-Effects in Patients With Gastrointestinal Cancers, RT-CAMSS Study | completed | N/A | 34 | Thomas Jefferson UniversityOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT05658263 | Bacterial Intestinal Gut Modification Around Cancer Surgery (BIG MACS) Diet | completed | Early Phase 1 | 14 | University of MinnesotaOTHER | 1 | May 13, 2025 | clinicaltrials |
| NCT00574353 | Study Using Fluorine-18-Labeled Fluoro-Misonidazole Positron Emission Tomography to Detect Hypoxia in Locally Advanced (T3-T4 and./or N1)Primary Rectal Cancer Patients | completed | N/A | 23 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 9, 2025 | clinicaltrials |
| NCT06137248 | Study to Assess Colonic Microbiota Changes in Response to Energy Drink Consumption(ROSANNA) | completed | Phase 2 | 76 | University of FloridaOTHER | 1 | May 6, 2025 | clinicaltrials |
| NCT02272244 | Increasing Colorectal Cancer (CRC) Screening Among Hispanic Primary Care Patients | completed | N/A | 400 | Thomas Jefferson UniversityOTHER | 1 | May 4, 2025 | clinicaltrials |
| NCT06124131 | Building Engagement Using Financial Incentives Trial - Colorectal Cancer Screening(BENEFIT-C) | completed | N/A | 50 | Tulane UniversityOTHER | 1 | May 4, 2025 | clinicaltrials |
| NCT01972737 | Phase I Study of Ad5-hGCC (Human Guanylyl Cyclase C)-PADRE in Stage I/II Colon Cancer | completed | Phase 1 | 10 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 2, 2025 | clinicaltrials |
| NCT02632448 | A Study of LY2880070 in Participants With Advanced or Metastatic Cancer | completed | Phase 1 / Phase 2 | 229 | Esperas Pharma Inc.OTHER | 4 | May 2, 2025 | clinicaltrials |
| NCT04328740 | Phase 1 Study of Oral TP-1454 | completed | Phase 1 | 31 | Sumitomo Pharma America, Inc.INDUSTRY | 1 | May 1, 2025 | clinicaltrials |
| NCT04495621 | MEN1611 With Cetuximab in Metastatic Colorectal Cancer (C-PRECISE-01)(C-PRECISE-01) | completed | Phase 1 / Phase 2 | 29 | Menarini GroupINDUSTRY | 7 | May 1, 2025 | clinicaltrials |
| NCT06573424 | Tirellizumab+Anlotinib VS Anlotinib for MSS-type CRC | completed | — | 124 | fan liOTHER | 1 | May 1, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Jul 3, 2025source: clinicaltrials