Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,500 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06405776 | Effect of Lidocaine on Postoperative Pain and Long-term Survival in Elderly Patients Undergoing Colorectal Surgery | recruiting | N/A | 276 | West China HospitalOTHER | 1 | May 8, 2024 | clinicaltrials |
| NCT05539677 | Biobank and Register of Patients With Agresive Tumors for Translational and Analytical Research(REGATA) | recruiting | — | 1,000 | N.N. Petrov National Medical Research Center of OncologyOTHER | 1 |
| May 6, 2024 |
| clinicaltrials |
| NCT05228431 | Modified Sandwich Therapeutic Regimen for Locally Advanced Rectal Cancer | recruiting | Phase 2 | 121 | Zhen-Hai LuOTHER | 1 | Apr 22, 2024 | clinicaltrials |
| NCT05485077 | A Prospective Cohort Study on Colorectal Cancer Screening in Community Population | recruiting | — | 18,000 | Singlera Genomics Inc.INDUSTRY | 1 | Apr 17, 2024 | clinicaltrials |
| NCT03465982 | Timing to Minimally Invasive Surgery After Neoadjuvant Chemoradiotherapy for Rectal Cancer(TiMiSNAR) | recruiting | N/A | 340 | Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di AlessandriaOTHER | 1 | Apr 16, 2024 | clinicaltrials |
| NCT05714124 | Liver Embolization Approaches for Tumor Management(LEATUM) | recruiting | — | 580 | IRCCS San RaffaeleOTHER | 1 | Apr 12, 2024 | clinicaltrials |
| NCT06350370 | Short-term and Long-term Outcomes of Colorectal Cancer Treated With Natural Orifice Specimen Extraction Surgery : a National Registry-based Study | recruiting | N/A | 8,000 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Apr 5, 2024 | clinicaltrials |
| NCT06202001 | Irinotecan, TAS-102 Plus Bevacizumab as a Second-Line Therapy in mCRC Patients | recruiting | Phase 1 / Phase 2 | 70 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Apr 2, 2024 | clinicaltrials |
| NCT06331988 | Microbiome, Immune-system and Tumor Interaction in Colorectal Cancer(MITICO) | recruiting | — | 320 | European Institute of OncologyOTHER | 1 | Mar 27, 2024 | clinicaltrials |
| NCT06327568 | Anal Cancer and/or Precancer Screening: Performance Analysis of the BD Onclarity™ HPV Assay on Anal Specimens | recruiting | — | 200 | European Institute of OncologyOTHER | 1 | Mar 26, 2024 | clinicaltrials |
| NCT06326879 | A Comparative Study Between Early Onset Colorectal Cancer and Late Onset Colorectal Cancer Patients(EOrOS) | recruiting | — | 340 | Istituto Clinico HumanitasOTHER | 1 | Mar 25, 2024 | clinicaltrials |
| NCT06265025 | GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors | recruiting | Phase 1 / Phase 2 | 125 | GeneMedicine Co., Ltd.INDUSTRY | 1 | Mar 21, 2024 | clinicaltrials |
| NCT05224518 | Exercise Intervention to Improve Quality of Life in Patients With Colorectal Cancer | recruiting | N/A | 106 | National Taiwan University Hospital Hsin-Chu BranchOTHER | 1 | Mar 19, 2024 | clinicaltrials |
| NCT05883800 | Total Neoadjuvant Treatment Combined With Adaptive Radiotherapy for Rectal Cancer(TNT-RECORD) | recruiting | N/A | 61 | Haukeland University HospitalOTHER | 1 | Mar 19, 2024 | clinicaltrials |
| NCT06234007 | Short-course Radiotherapy Followed by Fruquintinib Plus Adebrelimab and CAPOX in the Full Course Neoadjuvant Treatment of Locally Advanced Rectal Cancer: a Multicenter, Single-arm, Open-label Study | recruiting | Phase 2 | 45 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Mar 18, 2024 | clinicaltrials |
| NCT06307249 | Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA(PTST_PALBEVA) | recruiting | Phase 1 | 50 | Lebanese UniversityOTHER | 1 | Mar 12, 2024 | clinicaltrials |
| NCT06293014 | TAS-102 Combined With Bevacizumab for Second-line Maintenance Treatment of Advanced Colorectal Cancer | recruiting | Phase 2 | 224 | Henan Cancer HospitalOTHER_GOV | 1 | Mar 5, 2024 | clinicaltrials |
| NCT06281145 | Stress-Reducing Intervention in Patients With Colorectal and Breast Cancer(SRI-BrCa_CRC) | recruiting | N/A | 100 | Comenius UniversityOTHER | 1 | Feb 28, 2024 | clinicaltrials |
| NCT05495048 | Transvaginal NOSES Versus Conventional Laparoscopic Surgery for Right Hemicolectomy | recruiting | N/A | 356 | Shanghai Minimally Invasive Surgery CenterOTHER | 1 | Feb 26, 2024 | clinicaltrials |
| NCT06270017 | Evaluation of Metastatic Disease and Oncological Treatment in Patients With Colon Cancer Using Zebra Fish Avatars(ZEBRA-COLON) | recruiting | Phase 1 / Phase 2 | 300 | University Hospital, LinkoepingOTHER | 1 | Feb 21, 2024 | clinicaltrials |
| NCT06266832 | The Efficacy and Safety of Short-course Radiation Combined With Adebrelimab and CAPEOX Neo-adjuvant Therapy for Organ-retention in Patients With MSS/pMMR Ultra Low Rectal Adenocarcinoma | recruiting | Phase 2 | 30 | Sir Run Run Shaw HospitalOTHER | 1 | Feb 20, 2024 | clinicaltrials |
| NCT06057350 | Surgery Versus Endoscopic Resection for Incompletely Removed Early Colon CAnceR(SCAR) | recruiting | N/A | 304 | Norwegian Department of Health and Social AffairsOTHER_GOV | 2 | Feb 16, 2024 | clinicaltrials |
| NCT05007132 | Trifluridine/ Tipiracil Plus Panitumumab Versus Trifluridine/ Tipiracil Plus Bevacizumab as First-line Treatment of Metastatic Colorectal Cancer | recruiting | Phase 2 | 153 | Dominik Paul ModestOTHER | 1 | Feb 15, 2024 | clinicaltrials |
| NCT06254521 | The Effects of Neoadjuvant Tislelizumab Combined With Chemotherapy in Locally Advanced MSS Rectal Cancer | recruiting | Phase 2 | 60 | First Affiliated Hospital of Guangxi Medical UniversityOTHER | 1 | Feb 12, 2024 | clinicaltrials |
| NCT04282044 | Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies | recruiting | Phase 1 | 60 | BioEclipse TherapeuticsINDUSTRY | 1 | Feb 8, 2024 | clinicaltrials |
| NCT01479608 | Liver Transplantation and Colorectal Cancer | recruiting | N/A | 25 | Oslo University HospitalOTHER | 1 | Feb 7, 2024 | clinicaltrials |
| NCT02215889 | Partial Liver Segment 2/3 Transplantation Study | recruiting | Phase 1 / Phase 2 | 20 | Oslo University HospitalOTHER | 1 | Feb 6, 2024 | clinicaltrials |
| NCT03494946 | Liver Transplantation Compared to Chemotherapy in Patients With ColoRectal Cancer(SECAIII) | recruiting | N/A | 30 | Oslo University HospitalOTHER | 1 | Feb 6, 2024 | clinicaltrials |
| NCT06242067 | Second-line Treatment of Metastatic Colorectal Cancer(BEV-TASIRI) | recruiting | Phase 2 | 50 | Qilu Hospital of Shandong UniversityOTHER | 1 | Feb 5, 2024 | clinicaltrials |
| NCT05952947 | HRYZ-T101 Injection for HPV18 Positive Solid Tumor | recruiting | Phase 1 | 32 | HRYZ Biotech Co.INDUSTRY | 1 | Feb 2, 2024 | clinicaltrials |
| NCT06220617 | Multi-omics Study for Early Detection of Colorectal Cancer (MOED-CRC) | recruiting | — | 3,600 | Zhejiang UniversityOTHER | 1 | Jan 30, 2024 | clinicaltrials |
| NCT06229041 | Total Neoadjuvant Treatment ±Immunotherapy for High Risk Locally Advanced Rectal Cancer (TNTi) | recruiting | Phase 3 | 472 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jan 29, 2024 | clinicaltrials |
| NCT05746897 | A First-in-human, Phase I, Open-label, Multicenter Study of NM1F(Anti-PVRIG) in Patients With Advanced Solid Tumors | recruiting | Phase 1 | 38 | Hefei TG ImmunoPharma Co., Ltd.OTHER | 1 | Jan 26, 2024 | clinicaltrials |
| NCT06222255 | The Safety and Efficacy of Transanal Irrigation in Patients With Sleep Disturbance From Low Anterior Resection Syndrome After Rectal Cancer Surgery (TraLARS)(TraLARS) | recruiting | N/A | 52 | Seoul National University HospitalOTHER | 1 | Jan 24, 2024 | clinicaltrials |
| NCT04936581 | Patient Reported Outcomes Following Cancer of the Rectum(PROCaRe) | recruiting | — | 200 | University Hospital Gregorio MarañónOTHER | 1 | Jan 23, 2024 | clinicaltrials |
| NCT06218810 | Cadonilimab in Combination With Bevacizumab and FOLFOX Regimen for the First-Line Treatment of Advanced Unresectable MSS-Type, RAS-Mutated Metastatic Colorectal Cancer | recruiting | Phase 2 | 53 | Fudan UniversityOTHER | 1 | Jan 23, 2024 | clinicaltrials |
| NCT06204484 | MRD-guided Deferred Adjuvant Therapy in Resectable Early-stage Colon Cancer(MIRROR) | recruiting | N/A | 349 | Sun Yat-sen UniversityOTHER | 1 | Jan 12, 2024 | clinicaltrials |
| NCT05245474 | Neoadjuvant Long-course Chemoradiation Plus PD-1 Blockade for Mid-low Locally Advanced Rectal Cancer | recruiting | Phase 2 | 186 | Beijing Friendship HospitalOTHER | 1 | Jan 10, 2024 | clinicaltrials |
| NCT04235114 | Evaluation of 89Zr-DFO-nimotuzumab for Non-invasive Imaging of EGFR+ Cancers by Positron Emission Tomography (PET) | recruiting | Phase 1 / Phase 2 | 14 | University of SaskatchewanOTHER | 1 | Jan 9, 2024 | clinicaltrials |
| NCT06194708 | Reasons for Non-reversal of Temporary Stomas After Surgeries of Mid-low Rectal Cancer （NORESTO Study） | recruiting | — | 235 | Peking Union Medical College HospitalOTHER | 1 | Jan 8, 2024 | clinicaltrials |
| NCT04894370 | Combination of Spartalizumab, mDCF and Radiotherapy in Patients With Metastatic Squamous Cell Anal Carcinoma(SPARTANA) | recruiting | Phase 2 | 34 | Centre Hospitalier Universitaire de BesanconOTHER | 1 | Dec 22, 2023 | clinicaltrials |
| NCT05991102 | Amplitude Modulated Radiofrequency Electromagnetic Field Treatment Combined With TAS-102 (Lonsurf) and Bevacizumab in Refractory Metastatic Colorectal Cancer(Live-RF) | recruiting | N/A | 12 | Charite University, Berlin, GermanyOTHER | 1 | Dec 21, 2023 | clinicaltrials |
| NCT06168786 | Cadonilimab Combined With Fruquintinib and SBRT as Athird-line and Posterior Line Treatment in Patients With MSS CRC | recruiting | Phase 2 | 40 | Huazhong University of Science and TechnologyOTHER | 1 | Dec 21, 2023 | clinicaltrials |
| NCT03908684 | Ultrasound Spectroscopy as Early Indicators of Radiation Treatment Response in Prostate, Rectum and Head & Neck Cancers | recruiting | — | 320 | Sunnybrook Health Sciences CentreOTHER | 1 | Dec 13, 2023 | clinicaltrials |
| NCT04792892 | ANCA II - Quality of Life and Functional Outcome in Patients With Anal Cancer(ANCAII) | recruiting | — | 600 | Sahlgrenska University HospitalOTHER | 1 | Dec 8, 2023 | clinicaltrials |
| NCT02649647 | Proximally Extended Resection for Rectal Cancer After Neoadjuvant Chemoradiotherapy(PERN) | recruiting | N/A | 240 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Dec 6, 2023 | clinicaltrials |
| NCT04754672 | Aerobic Fitness or Muscle Mass Training to Improve Colorectal Cancer Outcome(AMICO) | recruiting | N/A | 228 | Radboud University Medical CenterOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT06134388 | Sulfasalazine in Patients With Metastatic Colorectal Cancer | recruiting | Phase 3 | 50 | Tanta UniversityOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT06136949 | The Theranostic Value of STARD3 in Colorectal Cancer: The STAR Study(STAR) | recruiting | — | 150 | Centro di Riferimento Oncologico - AvianoOTHER | 1 | Nov 18, 2023 | clinicaltrials |
Data updated 23 days agoSource updated May 8, 2024source: clinicaltrials