Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,500 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02038699 | A First-in-man Phase I/II Study of Oral ONC201 in Patients With Advanced Cancer | withdrawn | Phase 1 / Phase 2 | 0 | Jazz PharmaceuticalsINDUSTRY | 1 | Apr 30, 2021 | clinicaltrials |
| NCT03576963 | Guadecitabine and Nivolumab in Treating Refractory Metastatic Colorectal Cancer | withdrawn | Phase 1 / Phase 2 | 0 | University of Southern CaliforniaOTHER | 1 | Apr 5, 2021 | clinicaltrials |
| NCT01097239 |
| Examining the Role of Transrectal High Intensity Focused Ultrasound (HIFU) in Rectal Pelvic Cancer |
| withdrawn |
| Phase 1 / Phase 2 |
| 0 |
| Imperial College LondonOTHER |
| 1 |
| Nov 20, 2020 |
| clinicaltrials |
| NCT03524274 | Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Colorectal Cancer | withdrawn | Phase 2 | 0 | Fuda Cancer Hospital, GuangzhouOTHER | 1 | Oct 19, 2020 | clinicaltrials |
| NCT01302613 | Altered Chemotherapy Sequencing During Neoadjuvant Therapy for Patients With Stage II or III Rectal Adenocarcinoma | withdrawn | Phase 1 / Phase 2 | 0 | University of Texas Southwestern Medical CenterOTHER | 1 | Aug 20, 2020 | clinicaltrials |
| NCT02713984 | A Clinical Research of CAR T Cells Targeting HER2 Positive Cancer | withdrawn | Phase 1 / Phase 2 | 0 | Zhi YangOTHER | 1 | Mar 19, 2020 | clinicaltrials |
| NCT03688230 | Study of Abituzumab in Combination With Cetuximab and FOLFIRI in Patients With Metastatic Colorectal Cancer.(AMELION) | withdrawn | Phase 2 | 0 | SFJ Pharmaceuticals X, LTD.INDUSTRY | 0 | Mar 18, 2020 | clinicaltrials |
| NCT03323424 | Phase II Trial Assessing the Efficacy of Immuno-Radiation Abscopal Effect in Patients With Metastatic Cancers(IRAM) | withdrawn | Phase 2 | 0 | Institut de Cancérologie de la LoireOTHER | 1 | Jan 30, 2020 | clinicaltrials |
| NCT01741038 | AlloStim® In-Situ Vaccine in Pre-Treated Metastatic Colorectal Cancer | withdrawn | Phase 2 / Phase 3 | 0 | Mirror Biologics, Inc.INDUSTRY | 1 | Jan 22, 2020 | clinicaltrials |
| NCT03272659 | The Correlation of Surgical Colorectal Cancer Specimen Pathology With the Fluorescence of Photodynamic Diagnostics(PDD) | withdrawn | Phase 2 | 0 | Dr. Te VuongOTHER | 0 | Sep 18, 2019 | clinicaltrials |
| NCT03161574 | FOLFOXIRI Chemotherapy Alone as Neoadjuvant Treatment for Circumferential Radial Margin (CRM) Positive Rectal Cancer | withdrawn | Phase 2 | 0 | Guangxi Medical UniversityOTHER | 1 | Aug 8, 2019 | clinicaltrials |
| NCT03340558 | Atezolizumab Monotherapy vs Atezolizumab Plus Cobimetinib in Liver Metastases From Colorectal Cancer(ATELIER) | withdrawn | Phase 2 | 0 | Niharika MettuOTHER | 1 | Oct 9, 2018 | clinicaltrials |
| NCT03182894 | Epacadostat in Combination With Pembrolizumab and Azacitidine in Subjects With Metastatic Colorectal Cancer | withdrawn | Phase 1 / Phase 2 | 0 | James J LeeOTHER | 1 | Aug 28, 2018 | clinicaltrials |
| NCT00577109 | A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Previously Untreated Metastatic Colorectal Cancer. | withdrawn | Phase 2 | 0 | Hoffmann-La RocheINDUSTRY | 1 | Jul 31, 2018 | clinicaltrials |
| NCT03222089 | Phase II Trial of FOLFOXIGIL Versus FOLFOXIRI as First-line Therapy in Patients With mCRC | withdrawn | Phase 2 | 0 | Fujian Cancer HospitalOTHER_GOV | 1 | Mar 27, 2018 | clinicaltrials |
| NCT03307603 | Yttrium-90 Radioembolization + Nivolumab for Liver + Extra-hepatic Metastases From Colorectal Cancer | withdrawn | Phase 1 / Phase 2 | 0 | Case Comprehensive Cancer CenterOTHER | 0 | Feb 27, 2018 | clinicaltrials |
| NCT00388700 | A New Agent GM-CT-01 in Combination With 5-FU, Avastin and Leucovorin in Subjects With Colorectal Cancer | withdrawn | Phase 2 | 0 | Galectin Therapeutics Inc.INDUSTRY | 1 | Feb 14, 2018 | clinicaltrials |
| NCT03264274 | Trial of Aflibercept Monotherapy With DCE-US in Chemorefractory Metastatic Colorectal Cancer(AUSCOR) | withdrawn | Phase 2 | 0 | Barts & The London NHS TrustOTHER | 0 | Aug 31, 2017 | clinicaltrials |
| NCT02345746 | Hepatic Arterial Infusion With FOLFOX Alone or in Combination With IV Chemotherapy in Colon Cancer With Liver Metastasis | withdrawn | Phase 2 | 0 | Western Regional Medical CenterOTHER | 0 | Aug 24, 2017 | clinicaltrials |
| NCT00002664 | Monoclonal Antibody Therapy and Colony- Stimulating Factor in Treating Patients With Metastatic Colorectal Cancer | withdrawn | Phase 2 | 0 | James AhlgrenOTHER | 1 | Jul 13, 2017 | clinicaltrials |
| NCT01095523 | Prospective Randomized Trial Evaluating Mandatory Second Look Surgery With HIPEC and CRS vs. Standard of Care in Subjects at High Risk of Developing Colorectal Peritoneal Metastases | withdrawn | Phase 2 | 0 | National Cancer Institute (NCI)NIH | 1 | Jul 2, 2017 | clinicaltrials |
| NCT01176500 | A Pilot, Open-label Study of 18F-Fluciclatide PET/CT Imaging in the Evaluation of Anti-angiogenic Therapy in Solid Tumors | withdrawn | Phase 1 / Phase 2 | 0 | National Cancer Institute (NCI)NIH | 1 | Jul 2, 2017 | clinicaltrials |
| NCT00408772 | Oxaliplatin, Capecitabine, and Bevacizumab Followed By Surgery and/or Radiofrequency Ablation in Patients With Colorectal Cancer | withdrawn | Phase 2 | 0 | University of California, DavisOTHER | 1 | Jun 9, 2017 | clinicaltrials |
| NCT01646554 | Efficacy of FOLFOX Versus FOLFOX Plus Aflibercept in K-ras Mutant Patients With Resectable Liver Metastases(BOS3) | withdrawn | Phase 2 / Phase 3 | 0 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 0 | May 9, 2017 | clinicaltrials |
| NCT02413853 | Combination Chemotherapy and Bevacizumab With or Without PRI-724 in Treating Patients With Newly Diagnosed Metastatic Colorectal Cancer(PRIMIER) | withdrawn | Phase 2 | 0 | University of Southern CaliforniaOTHER | 1 | Apr 17, 2017 | clinicaltrials |
| NCT01270438 | Combination Chemotherapy and Bevacizumab With or Without RO4929097 in Treating Patients With Metastatic Colorectal Cancer | withdrawn | Phase 2 | 0 | National Cancer Institute (NCI)NIH | 1 | Apr 4, 2017 | clinicaltrials |
| NCT02857608 | A Prospective, Open-Label, Multi-center Comparison of Lymphoseek Identified Lymph Nodes and Clinically Identified Lymph Nodes of Subjects With Known Cancer of the Anus | withdrawn | Phase 2 | 0 | Cardinal Health 414, LLCINDUSTRY | 0 | Mar 15, 2017 | clinicaltrials |
| NCT02965417 | Sym004 in Metastatic Colorectal Cancer and ECD-EGFR Patients | withdrawn | Phase 2 | 0 | Symphogen A/SINDUSTRY | 0 | Feb 1, 2017 | clinicaltrials |
| NCT02046538 | Phase II Study of Zaltrap and Chemotherapy for Advanced Resectable Colorectal Cancer | withdrawn | Phase 2 | 0 | Weill Medical College of Cornell UniversityOTHER | 1 | Jan 25, 2017 | clinicaltrials |
| NCT02586610 | Trial of Chemoradiation and Pembrolizumab in Patients With Rectal Cancer | withdrawn | Phase 2 | 0 | Osama Rahma, MDOTHER | 0 | Jan 20, 2017 | clinicaltrials |
| NCT02785068 | Evaluation of MM-151 + Nal-IRI + 5-FU + Leucovorin in RAS/RAF Wild-type Metastatic Colorectal Cancer | withdrawn | Phase 1 / Phase 2 | 0 | Merrimack PharmaceuticalsINDUSTRY | 0 | Jan 11, 2017 | clinicaltrials |
| NCT01522677 | A Study of Neoadjuvant Photodynamic Immunomodulation for Colon Cancer | withdrawn | Phase 1 / Phase 2 | 0 | Edward NelsonOTHER | 1 | Dec 1, 2016 | clinicaltrials |
| NCT02287727 | Regorafenib in Reducing Recurrence in Patients With Non-metastatic Rectal Cancer Who Have Completed Curative-Intent Treatment | withdrawn | Phase 2 | 0 | Roswell Park Cancer InstituteOTHER | 1 | Oct 12, 2016 | clinicaltrials |
| NCT00571740 | Cetuximab and Bevacizumab as First-Line Therapy Followed By Combination Chemotherapy and Bevacizumab With or Without Cetuximab as Second-Line Therapy in Treating Patients With Stage IV Colorectal Cancer | withdrawn | Phase 2 | 0 | Alliance for Clinical Trials in OncologyOTHER | 0 | Jul 6, 2016 | clinicaltrials |
| NCT02575508 | Pan FGFR Kinase Inhibitor BGJ398 and Combination Chemotherapy in Treating Patients With Untreated Metastatic Pancreatic Cancer | withdrawn | Phase 1 / Phase 2 | 0 | Roswell Park Cancer InstituteOTHER | 1 | May 20, 2016 | clinicaltrials |
| NCT01157039 | A Trial of Glutamine to Prevent Oxaliplatin Neurotoxicity and a Pharmacokinetic Analysis of Oxaliplatin | withdrawn | Phase 2 | 0 | AHS Cancer Control AlbertaOTHER | 0 | Feb 24, 2016 | clinicaltrials |
| NCT01501604 | BKM120 in Cancers With PIK3CA Activating Mutations | withdrawn | Phase 2 | 0 | Massachusetts General HospitalOTHER | 0 | Sep 17, 2015 | clinicaltrials |
| NCT00244348 | Hepatic Artery Infusion With Oxaliplatin | withdrawn | Phase 1 / Phase 2 | 0 | Medical College of WisconsinOTHER | 1 | Aug 27, 2015 | clinicaltrials |
| NCT00735241 | FOLFOX6 Plus Sir-Spheres Microspheres Plus Avastin in Patients With Nonresectable Liver Metastases From Colorectal Carcinoma(FAST) | withdrawn | Phase 2 / Phase 3 | 0 | Sirtex MedicalINDUSTRY | 1 | May 22, 2015 | clinicaltrials |
| NCT02235324 | Ziv-Aflibercept Followed by Ziv-Aflibercept, Fluorouracil, and Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer | withdrawn | Phase 2 | 0 | University of Southern CaliforniaOTHER | 1 | May 6, 2015 | clinicaltrials |
| NCT00575640 | Hydralazine as a Demethylating Agent in Rectal Cancer | withdrawn | Phase 1 / Phase 2 | 0 | University of ArkansasOTHER | 0 | Mar 4, 2015 | clinicaltrials |
| NCT01659424 | Phase II Trial of Preoperative High-dose-rate Endorectal Brachytherapy and FOLFOX Chemotherapy for Rectal Cancer(HDRBT) | withdrawn | Phase 2 | 0 | Beth Israel Medical CenterOTHER | 1 | Dec 18, 2014 | clinicaltrials |
| NCT01889680 | Safety and Effectiveness Study of Chemotherapy and Ziv-aflibercept to Treat Metastatic Colorectal Cancer | withdrawn | Phase 2 | 0 | NSABP Foundation IncNETWORK | 0 | Dec 2, 2014 | clinicaltrials |
| NCT01320267 | Single Port Laparoscopic Colectomy(SILS) | withdrawn | Phase 1 / Phase 2 | 0 | University of British ColumbiaOTHER | 0 | Mar 17, 2014 | clinicaltrials |
| NCT00003786 | Irofulven in Treating Patients With Metastatic or Recurrent Colorectal Cancer | withdrawn | Phase 2 | 0 | University of ChicagoOTHER | 1 | Mar 7, 2014 | clinicaltrials |
| NCT00026468 | Exisulind in Preventing Polyps in Patients With Familial Adenomatous Polyposis | withdrawn | Phase 2 / Phase 3 | 0 | University of UtahOTHER | 0 | Jul 24, 2013 | clinicaltrials |
| NCT00003486 | Antineoplaston Therapy in Treating Patients With Colon Cancer | withdrawn | Phase 2 | 0 | Burzynski Research InstituteOTHER | 1 | Jul 10, 2013 | clinicaltrials |
| NCT01293942 | IXO+A in mCRC With Liver-only Metastases | withdrawn | Phase 2 | 0 | Ottawa Hospital Research InstituteOTHER | 1 | Jun 5, 2013 | clinicaltrials |
Data updated 22 days agoSource updated Apr 30, 2021source: clinicaltrials