Subtype
Malignant Hepatobiliary Neoplasm
CI-CAN-00001136Explore in graph →
1,159 active trials17 approved drugs42 evidence items
- NCIt
- C8609
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Subtype
CI-CAN-00001136Explore in graph →
Clinical trials
5,025 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (560)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00712855 | A Study of Mapatumumab in Combination With Sorafenib in Subjects With Advanced Hepatocellular Carcinoma(HCC) | completed | Phase 1 | 23 | Human Genome Sciences Inc., a GSK CompanyINDUSTRY | 1 | Oct 30, 2012 | clinicaltrials |
| NCT00966251 | Safety and Tolerability Study of the Monoclonal Antibody CT-011 in Patients With Hepatocellular Carcinoma | terminated | Phase 1 / Phase 2 | 2 | CureTech LtdINDUSTRY | 1 | Oct 23, 2012 |
| clinicaltrials |
| NCT00093548 | Vaccine Therapy in Treating Patients With Stage II, Stage IIIA, Stage IIIB, or Stage IVA Liver Cancer | withdrawn | Phase 1 / Phase 2 | 0 | Jonsson Comprehensive Cancer CenterOTHER | 0 | Oct 4, 2012 | clinicaltrials |
| NCT01213030 | Clinical Evaluation of the New Hypoxia Imaging Agent HX4 | completed | Phase 1 / Phase 2 | 12 | Siemens Molecular ImagingINDUSTRY | 1 | Sep 25, 2012 | clinicaltrials |
| NCT00293436 | Celecoxib and Erlotinib in Treating Patients With Liver Cancer | withdrawn | Phase 1 / Phase 2 | 0 | University of California, San FranciscoOTHER | 1 | Sep 17, 2012 | clinicaltrials |
| NCT00614913 | Proton Beam Therapy for Treatment of Hepatocellular Carcinoma | completed | Phase 1 / Phase 2 | 76 | Loma Linda UniversityOTHER | 1 | Aug 20, 2012 | clinicaltrials |
| NCT00426829 | Proton Therapy and Bevacizumab for Primary Liver Tumors | terminated | Phase 1 | 3 | M.D. Anderson Cancer CenterOTHER | 1 | Aug 1, 2012 | clinicaltrials |
| NCT00003046 | Interleukin-12 in Treating Patients With Cancer in the Abdomen | completed | Phase 1 | 29 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 30, 2012 | clinicaltrials |
| NCT00507585 | Hepatic Arterial Infusion of Oxaliplatin, Fluorouracil, Leucovorin, and Avastin | completed | Phase 1 | 63 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 30, 2012 | clinicaltrials |
| NCT00802555 | Safety Study of ARQ 197 in Cirrhotic Patients With Hepatocellular Carcinoma (HCC) | completed | Phase 1 | 21 | ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)INDUSTRY | 3 | Jul 12, 2012 | clinicaltrials |
| NCT00999882 | Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Efficacy of Tor Kinase Inhibitor in Liver Cancer Patients | completed | Phase 1 | 26 | AstraZenecaINDUSTRY | 2 | Jul 10, 2012 | clinicaltrials |
| NCT00731445 | Phase I/II Study of Z-208 in Advanced Hepatocellular Carcinoma (HCC) | completed | Phase 1 / Phase 2 | 43 | Zeria PharmaceuticalINDUSTRY | 1 | Jul 3, 2012 | clinicaltrials |
| NCT00562666 | Immunotherapy of Hepatocellular Carcinoma With Gamma Delta T Cells(ICAR) | terminated | Phase 1 | 2 | Rennes University HospitalOTHER | 1 | Jun 22, 2012 | clinicaltrials |
| NCT00057980 | Epirubicin and Celecoxib in Treating Patients With Hepatocellular Carcinoma | completed | Phase 1 / Phase 2 | 8 | Northwestern UniversityOTHER | 1 | Jun 11, 2012 | clinicaltrials |
| NCT00004910 | Endoscopic Placement of Metal Stents in Treating Patients With Cancer- Related Duodenal Obstruction | completed | Phase 1 / Phase 2 | — | Northwestern UniversityOTHER | 1 | Jun 6, 2012 | clinicaltrials |
| NCT00767468 | Sorafenib in Treating Patients With Locally Advanced or Metastatic Liver Cancer and Cirrhosis | terminated | Phase 1 | 6 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | May 23, 2012 | clinicaltrials |
| NCT00662246 | Dose Escalation Study Using Proton Beam Radiotherapy for Hepatocellular Carcinoma | completed | Phase 1 | 24 | National Cancer Center, KoreaOTHER_GOV | 1 | Apr 3, 2012 | clinicaltrials |
| NCT00784290 | Phase I/II Study of TSU-68 for Advanced Hepatocellular Carcinoma | completed | Phase 1 / Phase 2 | 35 | Taiho Pharmaceutical Co., Ltd.INDUSTRY | 1 | Mar 26, 2012 | clinicaltrials |
| NCT00019513 | Combination Chemotherapy in Treating Patients With Recurrent, Refractory, or Metastatic Solid Tumors or Lymphomas | completed | Phase 1 | 108 | National Institutes of Health Clinical Center (CC)NIH | 1 | Mar 23, 2012 | clinicaltrials |
| NCT00873002 | Panobinostat and Sorafenib in Treating Patients With Liver Cancer That is Metastatic and/or Cannot Be Removed by Surgery | terminated | Phase 1 | 3 | Case Comprehensive Cancer CenterOTHER | 1 | Mar 20, 2012 | clinicaltrials |
| NCT00030108 | Ixabepilone in Treating Young Patients With Solid Tumors or Leukemia That Haven't Responded to Therapy | completed | Phase 1 | 30 | National Institutes of Health Clinical Center (CC)NIH | 1 | Mar 15, 2012 | clinicaltrials |
| NCT00036959 | ABT-751 in Treating Young Patients With Refractory Solid Tumors | completed | Phase 1 | 90 | National Institutes of Health Clinical Center (CC)NIH | 1 | Mar 15, 2012 | clinicaltrials |
| NCT00093444 | Heat Activated Liposomal Doxorubicin and Radiofrequency Ablation in Treating Patients With Primary or Metastatic Liver Tumors | completed | Phase 1 | 30 | National Institutes of Health Clinical Center (CC)NIH | 2 | Mar 15, 2012 | clinicaltrials |
| NCT00303940 | Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors | completed | Phase 1 | 26 | National Institutes of Health Clinical Center (CC)NIH | 1 | Mar 15, 2012 | clinicaltrials |
| NCT00988195 | Study of Pegylated Human Recombinant Arginase for Liver Cancer | completed | Phase 1 | 15 | Bio-Cancer Treatment International LimitedINDUSTRY | 1 | Mar 14, 2012 | clinicaltrials |
| NCT01092091 | Study of Pegylated Human Recombinant Arginase for Liver Cancer (BCT-100-002)(BCT-100-002) | completed | Phase 1 / Phase 2 | 20 | Bio-Cancer Treatment International LimitedINDUSTRY | 1 | Mar 14, 2012 | clinicaltrials |
| NCT00021047 | Epirubicin, Carboplatin, and Capecitabine in Treating Patients With Unresectable Locally Advanced, Metastatic, or Recurrent Solid Tumor | completed | Phase 1 / Phase 2 | — | National Institutes of Health Clinical Center (CC)NIH | 1 | Mar 8, 2012 | clinicaltrials |
| NCT00266097 | Oxaliplatin, Gemcitabine, Erlotinib, and Radiation Therapy in Treating Patients With Unresectable and/or Metastatic Pancreatic Cancer or Biliary Tract Cancer | completed | Phase 1 | 23 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Mar 7, 2012 | clinicaltrials |
| NCT01131689 | Trial of S-1 in Combination With Sorafenib for Patients With Advanced Hepatocellular Carcinoma | completed | Phase 1 | 20 | Samsung Medical CenterOTHER | 1 | Feb 2, 2012 | clinicaltrials |
| NCT01031784 | Radioactive Holmium Microspheres for the Treatment of Liver Metastases(HEPAR) | completed | Phase 1 | 15 | UMC UtrechtOTHER | 1 | Jan 31, 2012 | clinicaltrials |
| NCT01441388 | A Study Of Crizotinib Plus VEGF Inhibitor Combinations In Patients With Advanced Solid Tumors. | withdrawn | Phase 1 | 0 | PfizerINDUSTRY | 0 | Dec 20, 2011 | clinicaltrials |
| NCT00073736 | Safety and Tolerability of I.V. Infusion of MB07133 in Patients With Unresectable Hepatocellular Carcinoma | completed | Phase 1 / Phase 2 | 28 | Ligand PharmaceuticalsINDUSTRY | 3 | Aug 12, 2011 | clinicaltrials |
| NCT00882869 | XIAP Antisense AEG35156 in Combination With Sorafenib in Patients With Advanced Hepatocellular Carcinoma (HCC) | completed | Phase 1 / Phase 2 | 75 | Aegera TherapeuticsINDUSTRY | 1 | Jul 13, 2011 | clinicaltrials |
| NCT00437424 | A Study of Brivanib (BMS-582664) in Patients With Liver Cancer and Mild, Moderate or Severe Liver Dysfunction | completed | Phase 1 | 24 | Bristol-Myers SquibbINDUSTRY | 2 | May 4, 2011 | clinicaltrials |
| NCT01266707 | Antiangiogenic Peptide Vaccine Therapy in Treating Patient With Hepatocellular Carcinoma | unknown | Phase 1 | 9 | Fukushima Medical UniversityOTHER | 1 | Dec 24, 2010 | clinicaltrials |
| NCT01116154 | Vorinostat and Lenalidomide in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma | terminated | Phase 1 | 30 | City of Hope Medical CenterOTHER | 1 | Dec 9, 2010 | clinicaltrials |
| NCT00933816 | Study of Sorafenib In Combination With Low-dose 5-fluorouracil/Cisplatin (FP) Intraarterial Infusion Chemotherapy(SILIUS) | completed | Phase 1 / Phase 2 | 37 | Kindai UniversityOTHER | 1 | Nov 25, 2010 | clinicaltrials |
| NCT00768937 | Sorafenib and Transarterial Chemoembolization for Hepatocellular Carcinoma | completed | Phase 1 / Phase 2 | 22 | Medical University of ViennaOTHER | 1 | Nov 9, 2010 | clinicaltrials |
| NCT00478374 | Sorafenib With TACE to Treat Hepatocellular Carcinoma(S-TACE) | completed | Phase 1 | 21 | University of BernOTHER | 1 | Nov 2, 2010 | clinicaltrials |
| NCT00179816 | Tandem Peripheral Blood Stem Cell (PBSC) Rescue for High Risk Solid Tumors | unknown | Phase 1 / Phase 2 | 12 | Ann & Robert H Lurie Children's Hospital of ChicagoOTHER | 1 | Oct 11, 2010 | clinicaltrials |
| NCT00791544 | Dose Finding Study of AVE1642 in Patients With Advanced or Metastatic Liver Carcinoma | terminated | Phase 1 / Phase 2 | 13 | SanofiINDUSTRY | 1 | Aug 4, 2010 | clinicaltrials |
| NCT00423254 | Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer. | completed | Phase 1 | 12 | Mannkind CorporationINDUSTRY | 1 | Aug 3, 2010 | clinicaltrials |
| NCT00230347 | Evaluation of Stereotactic Radiosurgery For Liver Malignancies | completed | Phase 1 | 20 | Stanford UniversityOTHER | 1 | Apr 1, 2010 | clinicaltrials |
| NCT00909558 | Safety and Effectiveness Study of Autologous Natural Killer and Natural Killer T Cells on Cancer | suspended | Phase 1 | 24 | Envita Medical Center, Inc.INDUSTRY | 1 | Feb 24, 2010 | clinicaltrials |
| NCT00185874 | Phase I Intratumoral Dendritic Cell Immunotherapy in Thermally Ablated Liver Metastases | terminated | Phase 1 | 22 | Stanford UniversityOTHER | 1 | Jan 13, 2010 | clinicaltrials |
| NCT00999843 | Safety Study of Sorafenib Following Combined Therapy of Radiation and TACE for Liver Cancer | unknown | Phase 1 / Phase 2 | 30 | Fudan UniversityOTHER | 1 | Oct 22, 2009 | clinicaltrials |
| NCT00960167 | A Dose Escalation Trial of Radiation Therapy (RT) for Hepatocellular Carcinoma (HCC) | unknown | Phase 1 | 20 | National Taiwan University HospitalOTHER | 1 | Oct 15, 2009 | clinicaltrials |
| NCT00390195 | Randomized Phase I/II of RAD001 in Advanced Hepatocellular Carcinoma (HCC) | unknown | Phase 1 / Phase 2 | 134 | National Health Research Institutes, TaiwanOTHER | 1 | Jul 2, 2009 | clinicaltrials |
| NCT00848094 | Radiation Dose Escalation Study for Advanced Liver Cancer | completed | Phase 1 | 40 | Fudan UniversityOTHER | 0 | Feb 20, 2009 | clinicaltrials |
| NCT00319683 | A Study of ADH300004 and 5-Fluorouracil in Locally Advanced, Recurrent, or Metastatic Hepatocellular Carcinoma | terminated | Phase 1 / Phase 2 | — | Adherex Technologies, Inc.INDUSTRY | 3 | Dec 15, 2008 | clinicaltrials |
Data updated 23 days agoSource updated Oct 30, 2012source: clinicaltrials