Cancer
Malignant Gastric Neoplasm
CI-CAN-00001130Explore in graph →
Top-level652 active trials4 approved drugs55 evidence items
Loading cancer entity…
Cancer
CI-CAN-00001130Explore in graph →
Genomics
9 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
478 cases with simple somatic mutation data · 478 cases total · 2026-01-13 · mapped to Gastric Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TTN | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 217 |
| 478 |
| 45.4% |
| cbioportal |
| 2 | TP53 | Ssm | 190 | 478 | 39.7% | cbioportal |
| 3 | MUC16 | Ssm | 134 | 478 | 28% | cbioportal |
| 4 | LRP1B | Ssm | 104 | 478 | 21.8% | cbioportal |
| 5 | ARID1A | Ssm | 102 | 478 | 21.3% | cbioportal |
| 6 | SYNE1 | Ssm | 101 | 478 | 21.1% | cbioportal |
| 7 | OBSCN | Ssm | 95 | 478 | 19.9% | cbioportal |
| 8 | FLG | Ssm | 86 | 478 | 18% | cbioportal |
| 9 | FAT4 | Ssm | 85 | 478 | 17.8% | cbioportal |
| 10 | CSMD1 | Ssm | 84 | 478 | 17.6% | cbioportal |
| 11 | PCLO | Ssm | 80 | 478 | 16.7% | cbioportal |
| 12 | RYR2 | Ssm | 77 | 478 | 16.1% | cbioportal |
| 15 | HMCN1 | Ssm | 73 | 478 | 15.3% | cbioportal |
| 14 | FAT3 | Ssm | 73 | 478 | 15.3% | cbioportal |
| 13 | DNAH5 | Ssm | 73 | 478 | 15.3% | cbioportal |
| 17 | SPTA1 | Ssm | 69 | 478 | 14.4% | cbioportal |
| 16 | KMT2D | Ssm | 69 | 478 | 14.4% | cbioportal |
| 18 | ZFHX4 | Ssm | 69 | 478 | 14.4% | cbioportal |
| 19 | PIK3CA | Ssm | 65 | 478 | 13.6% | cbioportal |
| 20 | HSPG2 | Ssm | 63 | 478 | 13.2% | cbioportal |
| 21 | DNAH7 | Ssm | 62 | 478 | 13% | cbioportal |
| 23 | RYR3 | Ssm | 61 | 478 | 12.8% | cbioportal |
| 22 | PCDH15 | Ssm | 61 | 478 | 12.8% | cbioportal |
| 24 | SACS | Ssm | 60 | 478 | 12.6% | cbioportal |
| 26 | DNAH11 | Ssm | 59 | 478 | 12.3% | cbioportal |
| 28 | USH2A | Ssm | 59 | 478 | 12.3% | cbioportal |
| 25 | ACVR2A | Ssm | 59 | 478 | 12.3% | cbioportal |
| 27 | LRRK2 | Ssm | 59 | 478 | 12.3% | cbioportal |
| 30 | CUBN | Ssm | 58 | 478 | 12.1% | cbioportal |
| 29 | AHNAK2 | Ssm | 58 | 478 | 12.1% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13