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Genomics
3 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
244 cases with simple somatic mutation data · 244 cases total · 2026-04-07 · mapped to Gallbladder Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 | Ssm | 154 | 244 | 63.1% | cbioportal |
| 2 | SMAD4 | Ssm | 52 | 244 | 21.3% | cbioportal |
| 3 | ARID1A | Ssm | 50 | 244 | 20.5% | cbioportal |
| 7 | ELF3 | Ssm | 21 | 191 | 11% | cbioportal |
| 5 | PIK3CA | Ssm | 26 | 244 | 10.7% | cbioportal |
| 4 | CDKN2A | Ssm | 26 | 244 | 10.7% | cbioportal |
| 6 | STK11 | Ssm | 22 | 244 | 9% | cbioportal |
| 9 | KMT2C |
Data updated 21 days agoSource updated 2026-04-07
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 20 |
| 244 |
| 8.2% |
| cbioportal |
| 8 | ARID2 | Ssm | 20 | 244 | 8.2% | cbioportal |
| 10 | ERBB2 | Ssm | 19 | 244 | 7.8% | cbioportal |
| 152 | SMARCA2 | Ssm | 3 | 40 | 7.5% | cbioportal |
| 11 | KRAS | Ssm | 18 | 244 | 7.4% | cbioportal |
| 13 | ERBB3 | Ssm | 16 | 244 | 6.6% | cbioportal |
| 14 | KMT2D | Ssm | 16 | 244 | 6.6% | cbioportal |
| 12 | ATM | Ssm | 16 | 244 | 6.6% | cbioportal |
| 16 | TERT | Ssm | 15 | 244 | 6.1% | cbioportal |
| 15 | CTNNB1 | Ssm | 15 | 244 | 6.1% | cbioportal |
| 17 | BRCA2 | Ssm | 13 | 244 | 5.3% | cbioportal |
| 30 | SLX4 | Ssm | 9 | 191 | 4.7% | cbioportal |
| 28 | PREX2 | Ssm | 9 | 191 | 4.7% | cbioportal |
| 18 | RBM10 | Ssm | 11 | 244 | 4.5% | cbioportal |
| 20 | NF1 | Ssm | 10 | 244 | 4.1% | cbioportal |
| 21 | PBRM1 | Ssm | 10 | 244 | 4.1% | cbioportal |
| 19 | KMT2A | Ssm | 10 | 244 | 4.1% | cbioportal |
| 22 | RB1 | Ssm | 10 | 244 | 4.1% | cbioportal |
| 29 | RASA1 | Ssm | 9 | 244 | 3.7% | cbioportal |
| 26 | IKZF1 | Ssm | 9 | 244 | 3.7% | cbioportal |
| 25 | FBXW7 | Ssm | 9 | 244 | 3.7% | cbioportal |
| 27 | KEAP1 | Ssm | 9 | 244 | 3.7% | cbioportal |
| 23 | ATRX | Ssm | 9 | 244 | 3.7% | cbioportal |