Cancer
Malignant Esophageal Neoplasm
CI-CAN-00001127Explore in graph →
Top-level518 active trials6 approved drugs12 evidence items
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Cancer
CI-CAN-00001127Explore in graph →
Clinical trials
1,926 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (169)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05007145 | PD-1 Inhibitor Combined With Neoadjuvant Chemotherapy in Subjects With Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma(REVO) | unknown | Phase 2 | 92 | Fujian Cancer HospitalOTHER_GOV | 1 | Dec 21, 2021 | clinicaltrials |
| NCT04506138 | Camrelizumab in Combination With Neoadjuvant Chemotherapy for Resectable Thoracic Esophageal Squamous Cell Carcinoma | unknown | Phase 1 / Phase 2 | 46 | Zhejiang Cancer HospitalOTHER | 1 | Dec 14, 2021 |
| clinicaltrials |
| NCT02915432 | The Study to Evaluate Toripalimab (JS001) in Patients With Advanced GC, ESCC, NPC, HNSCC | unknown | Phase 1 / Phase 2 | 401 | Shanghai Junshi Bioscience Co., Ltd.OTHER | 1 | Dec 13, 2021 | clinicaltrials |
| NCT04286958 | A Study of Camrelizumab As Consolidation Therapy After Radical Concurrent Chemoradiotherapy In Locally Advanced ESCC(ESCC) | unknown | Phase 2 | 40 | Hebei Medical University Fourth HospitalOTHER | 1 | Dec 10, 2021 | clinicaltrials |
| NCT05130684 | Neo-NTP-CRT for Locally Advanced ESCC(Neo-NTP-CRT) | unknown | Phase 2 | 43 | National Taiwan University HospitalOTHER | 1 | Nov 23, 2021 | clinicaltrials |
| NCT02749513 | Itraconazole as a Targeted Therapy for Inhibiting Hedgehog Pathway Signaling in Esophageal Cancer Patients | unknown | Early Phase 1 | 18 | Dallas VA Medical CenterFED | 1 | Nov 4, 2021 | clinicaltrials |
| NCT05103501 | Salvage Immunotherapy and Chemotherapy in Esophageal Squamous Cell Carcinoma Patients Nonresponding to Initial Neoadjuvant Chemoradiotherapy(SINCERE) | unknown | Phase 2 | 54 | Shanghai Chest HospitalOTHER | 0 | Nov 2, 2021 | clinicaltrials |
| NCT04581005 | Prehabilitation in Esophageal Cancer Care | unknown | N/A | 54 | McGill University Health Centre/Research Institute of the McGill University Health CentreOTHER | 1 | Sep 28, 2021 | clinicaltrials |
| NCT05049681 | Study of Anti-PD-1 Antibody SHR-1210 Plus Apatinib vs SHR-1210 as Second-Line Treatment of Advanced Esophageal Squamous Cell | unknown | Phase 3 | 234 | Feng WangOTHER | 0 | Sep 20, 2021 | clinicaltrials |
| NCT04426955 | Study of Camrelizumab (SHR-1210) in Combination With Concurrent Chemoradiotherapy in Locally Advanced Esophageal Cancer | unknown | Phase 3 | 396 | Jiangsu HengRui Medicine Co., Ltd.INDUSTRY | 1 | Sep 16, 2021 | clinicaltrials |
| NCT05044728 | Exploration of Immunodynamic Monitoring in the Population Evaluation of Neoadjuvant Chemotherapy Immunotherapy in Patients With Solid Tumors of the Chest. | unknown | Phase 2 | 80 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Sep 16, 2021 | clinicaltrials |
| NCT03800953 | The Ave-CRT Study for Newly Diagnosed Metastatic Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 26 | National Taiwan University HospitalOTHER | 1 | Sep 8, 2021 | clinicaltrials |
| NCT03387904 | Study of Anlotinib Plus Irinotecan in Patients With Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 120 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Sep 2, 2021 | clinicaltrials |
| NCT04514835 | A Phase Ⅱ Trials of Sintilimab as Consolidation Therapy After Radical Concurrent Chemoradiotherapy in Locally Advanced Unresectable ESCC | unknown | Phase 2 | 44 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Aug 25, 2021 | clinicaltrials |
| NCT04063683 | Paclitaxel and DDP Combined With Anlotinib in the First-line Treatment for Patients With Advanced Esophageal Squamous Cell Carcinoma(ESCC). | unknown | Phase 2 | 47 | Henan Cancer HospitalOTHER_GOV | 1 | Aug 24, 2021 | clinicaltrials |
| NCT04533490 | A Phase Ⅱ Clinical Trial of Camrelizumab for Adjuvant Treatment of Resectable Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 42 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 0 | Aug 23, 2021 | clinicaltrials |
| NCT04654403 | Study of First-line Camrelizumab With or Without Chemotherapy for Advanced Esophageal Squamous Cell Cancer | unknown | N/A | 337 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Aug 23, 2021 | clinicaltrials |
| NCT04888403 | Exploring the Safety and Effectiveness of Toripalimab Combined With Neoadjuvant Radiotherapy and Chemotherapy in the Locally Advanced Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 45 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Aug 23, 2021 | clinicaltrials |
| NCT03962179 | Feasibility and Efficacy of a Combination of a SEMS and Vacuum Wound Treatment (VACStent)(VACStent) | unknown | N/A | 20 | University Hospital of CologneOTHER | 1 | Aug 5, 2021 | clinicaltrials |
| NCT04984018 | Chidamide Plus Camrelizumab as Second-line Therapy for Advanced ESCC Treated With PD-1 Blockade | unknown | Phase 2 | 73 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 0 | Jul 30, 2021 | clinicaltrials |
| NCT04984096 | Anlotinib Combined With PD-1 Inhibitors for Advanced/Metastatic Esophageal Cancer(APEC) | unknown | — | 50 | Shanghai Chest HospitalOTHER | 0 | Jul 30, 2021 | clinicaltrials |
| NCT04966611 | Anlotinib for Esophageal Cancer (AFEC) | unknown | — | 200 | Anyang Tumor HospitalOTHER | 1 | Jul 19, 2021 | clinicaltrials |
| NCT04880811 | Afatinib Plus Toripalimab in Previously Treated ESCC With EGFR Overexpression or EGFR Amplification | unknown | Phase 2 | 43 | Peking UniversityOTHER | 1 | Jul 13, 2021 | clinicaltrials |
| NCT03766178 | Study of Anti-PD-1 Antibody SHR-1210 Plus Nimotuzumab in the Treatment of Advanced Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 45 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Jul 7, 2021 | clinicaltrials |
| NCT04275986 | Concurrent Chemoradiotherapy After Endoscopic Resection for Stage I Esophageal Carcinoma | unknown | Phase 2 | 56 | Chinese Academy of Medical SciencesOTHER | 1 | Jul 7, 2021 | clinicaltrials |
| NCT03713749 | Robotic-assisted Esophagectomy vs. Video-Assisted Thoracoscopic Esophagectomy(REVATE) Trial | unknown | N/A | 212 | Chang Gung Memorial HospitalOTHER | 1 | Jul 1, 2021 | clinicaltrials |
| NCT04851132 | Radiotherapy Plus Durvalumab in Elderly Esophageal Squamous Cell Carcinoma | unknown | N/A | 33 | Chinese Academy of Medical SciencesOTHER | 1 | Jun 22, 2021 | clinicaltrials |
| NCT04894149 | Prehabilitation and Rehabilitation for Patients With Oesophageal Cancer(PRESO) | unknown | N/A | 25 | Gabriella Alexandersson von DöbelnOTHER | 1 | May 20, 2021 | clinicaltrials |
| NCT04866381 | An Exploratory Clinical Study of SHR6390 and SHR1020 in the Treatment of Esophageal Squamous Cell Carcinoma After Progression on PD-1 Antibody | unknown | Phase 2 | 87 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Apr 29, 2021 | clinicaltrials |
| NCT04843397 | Diagnostic Performance Indicators in Upper GI Endoscopy:PROSPERO Study(PROSPERO) | unknown | — | 1,000 | University of CambridgeOTHER | 0 | Apr 15, 2021 | clinicaltrials |
| NCT03585530 | Raltitrexed Concurrent With Radiotherapy for Elderly Chinese Patients With Squamous Cell Carcinoma of Esophagus | unknown | Phase 2 | 32 | Huai'an First People's HospitalOTHER | 1 | Apr 6, 2021 | clinicaltrials |
| NCT04818476 | Outcomes of Endoscopically Resected High-risk Mucosal and Low- and High-risk Submucosal Adenocarcinoma Arising in Barrett's Esophagus | unknown | — | 1,000 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 7 | Mar 26, 2021 | clinicaltrials |
| NCT04813406 | Study of Anlotinib Plus Sintilimab in the Treatment of Advanced Esophageal Squamous Cell Carcinoma | unknown | N/A | 53 | Henan Provincial People's HospitalOTHER | 0 | Mar 24, 2021 | clinicaltrials |
| NCT03619317 | Impact of Cancer Therapy on Myocardial Function in Patients With Esophagus Cancer(Heartcheck) | unknown | — | 56 | Aarhus University Hospital SkejbyOTHER | 1 | Mar 23, 2021 | clinicaltrials |
| NCT03535207 | High-dose Intensity Modulated Radiotherapy and Concurrent Chemotherapy in Esophageal Cancer | unknown | N/A | 50 | Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 1 | Mar 18, 2021 | clinicaltrials |
| NCT03936179 | High Dose PET/CT-guided Intensity Modulated Radiotherapy and Concurrent Chemotherapy in Esophageal Cancer | unknown | N/A | 50 | Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 1 | Mar 18, 2021 | clinicaltrials |
| NCT04804410 | Dielectric Properties of Matched Tissue Samples From Thoracic Malignancies and Corresponding Normal Tissues | unknown | N/A | 30 | University of Maryland, BaltimoreOTHER | 0 | Mar 18, 2021 | clinicaltrials |
| NCT04797507 | SHR-1210 in Combination With Anlotinib in Patients With Advanced or Metastatic Esophageal Squamous Cell Cancer | unknown | Phase 2 | 33 | Peking Union Medical College HospitalOTHER | 0 | Mar 15, 2021 | clinicaltrials |
| NCT04767295 | A Study of Camrelizumab Combined With Chemotherapy as Neoadjuvant Therapy in Adcanced Esophageal Squamous Cell Carcinoma (ESCC) | unknown | Phase 2 | 28 | Hunan Cancer HospitalOTHER | 1 | Feb 23, 2021 | clinicaltrials |
| NCT04759235 | Multimodal Functional Imaging Combined With Metabolomics in Predicting the Efficacy of nCRT for Locally Advanced ESCC | unknown | — | 118 | RenJi HospitalOTHER | 1 | Feb 18, 2021 | clinicaltrials |
| NCT04741490 | Camrelizumab Combined With Radiotherapy for Adjuvant Treatment of Esophageal Squamous Cell Carcinoma After Surgery | unknown | N/A | 20 | Fuzhou General HospitalOTHER | 1 | Feb 5, 2021 | clinicaltrials |
| NCT04514822 | Quantitative Evaluation of Metastatic Lymph Nodes With Dynamic 18F-FDG PET/CT in Patients With ESCC | unknown | N/A | 40 | Fifth Affiliated Hospital, Sun Yat-Sen UniversityOTHER | 1 | Feb 4, 2021 | clinicaltrials |
| NCT04014465 | Monitoring Efficacy of Radiotherapy in Lung Cancer and Esophageal Cancer | unknown | — | 150 | Chinese Academy of Medical SciencesOTHER | 1 | Feb 2, 2021 | clinicaltrials |
| NCT04694391 | Genomic Study of Relapse Esophageal Cancer After Radiotherapy | unknown | — | 200 | Fudan UniversityOTHER | 1 | Jan 26, 2021 | clinicaltrials |
| NCT03377400 | Definitive CCRT Combined With Durvalumab and Tremelimumab for Inoperable Esophageal Cancer | unknown | Phase 2 | 40 | Samsung Medical CenterOTHER | 1 | Dec 17, 2020 | clinicaltrials |
| NCT03987815 | Neoadjuvant Nivolumab for Operable Esophageal Carcinoma | unknown | Phase 2 | 20 | Samsung Medical CenterOTHER | 1 | Dec 17, 2020 | clinicaltrials |
| NCT03896958 | The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)(PIONEER) | unknown | — | 1,000 | SpeciCareINDUSTRY | 1 | Dec 4, 2020 | clinicaltrials |
| NCT04644250 | Combination of Toripalimab and Neoadjuvant Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 32 | Wei RenOTHER | 1 | Nov 25, 2020 | clinicaltrials |
| NCT03474341 | Preoperative Image-guided Identification of Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer(PRIDE) | unknown | — | 200 | UMC UtrechtOTHER | 1 | Nov 16, 2020 | clinicaltrials |
Data updated 22 days agoSource updated Dec 21, 2021source: clinicaltrials