Cancer
Malignant Esophageal Neoplasm
CI-CAN-00001127Explore in graph →
Top-level518 active trials6 approved drugs12 evidence items
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Cancer
CI-CAN-00001127Explore in graph →
Clinical trials
1,926 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (169)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03800953 | The Ave-CRT Study for Newly Diagnosed Metastatic Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 26 | National Taiwan University HospitalOTHER | 1 | Sep 8, 2021 | clinicaltrials |
| NCT03387904 | Study of Anlotinib Plus Irinotecan in Patients With Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 120 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Sep 2, 2021 | clinicaltrials |
| NCT04090554 | Cytosponge™ Feasibility Study in Tanzania(CytoSCCAPE) | completed | N/A | 101 | International Agency for Research on CancerOTHER | 1 | Aug 25, 2021 | clinicaltrials |
| NCT04514835 | A Phase Ⅱ Trials of Sintilimab as Consolidation Therapy After Radical Concurrent Chemoradiotherapy in Locally Advanced Unresectable ESCC | unknown | Phase 2 | 44 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Aug 25, 2021 | clinicaltrials |
| NCT03529266 | Study of Porcine Fibrin Sealant in Preventing Cervical Anastomotic Leakage for Esophageal or Junctional Carcinoma.(PLACE020) | completed | Phase 2 | 57 | Sun Yat-sen UniversityOTHER | 1 | Aug 24, 2021 | clinicaltrials |
| NCT04063683 | Paclitaxel and DDP Combined With Anlotinib in the First-line Treatment for Patients With Advanced Esophageal Squamous Cell Carcinoma（ESCC）. | unknown | Phase 2 | 47 | Henan Cancer HospitalOTHER_GOV | 1 | Aug 24, 2021 | clinicaltrials |
| NCT04533490 | A Phase Ⅱ Clinical Trial of Camrelizumab for Adjuvant Treatment of Resectable Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 42 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 0 | Aug 23, 2021 | clinicaltrials |
| NCT04654403 | Study of First-line Camrelizumab With or Without Chemotherapy for Advanced Esophageal Squamous Cell Cancer | unknown | N/A | 337 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Aug 23, 2021 | clinicaltrials |
| NCT04888403 | Exploring the Safety and Effectiveness of Toripalimab Combined With Neoadjuvant Radiotherapy and Chemotherapy in the Locally Advanced Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 45 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Aug 23, 2021 | clinicaltrials |
| NCT03734627 | Gastrointestinal Nutrient Transit and Enteroendocrine Function After Upper Gastrointestinal Surgery(EndoGut) | completed | — | 40 | St. James's Hospital, IrelandOTHER | 1 | Aug 16, 2021 | clinicaltrials |
| NCT01631552 | Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer | completed | Phase 1 / Phase 2 | 515 | Gilead SciencesINDUSTRY | 1 | Aug 12, 2021 | clinicaltrials |
| NCT01558648 | Quality of Life Outcomes Following Minimally Invasive and Open Esophagectomy for Esophageal Cancer | completed | — | 257 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Aug 6, 2021 | clinicaltrials |
| NCT03962179 | Feasibility and Efficacy of a Combination of a SEMS and Vacuum Wound Treatment (VACStent)(VACStent) | unknown | N/A | 20 | University Hospital of CologneOTHER | 1 | Aug 5, 2021 | clinicaltrials |
| NCT04984018 | Chidamide Plus Camrelizumab as Second-line Therapy for Advanced ESCC Treated With PD-1 Blockade | unknown | Phase 2 | 73 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 0 | Jul 30, 2021 | clinicaltrials |
| NCT04984096 | Anlotinib Combined With PD-1 Inhibitors for Advanced/Metastatic Esophageal Cancer(APEC) | unknown | — | 50 | Shanghai Chest HospitalOTHER | 0 | Jul 30, 2021 | clinicaltrials |
| NCT02452021 | Pencil Beam Scanning Proton Radiotherapy for Esophageal Cancer | completed | — | 30 | Mayo ClinicOTHER | 1 | Jul 27, 2021 | clinicaltrials |
| NCT04966611 | Anlotinib for Esophageal Cancer (AFEC) | unknown | — | 200 | Anyang Tumor HospitalOTHER | 1 | Jul 19, 2021 | clinicaltrials |
| NCT03787056 | Predictive Value of Progastrin Titer at Diagnosis and of Progastrin Kinetics During Treatment in Cancer Patients(ONCOPRO) | recruiting | N/A | 410 | Hospices Civils de LyonOTHER | 1 | Jul 16, 2021 | clinicaltrials |
| NCT04880811 | Afatinib Plus Toripalimab in Previously Treated ESCC With EGFR Overexpression or EGFR Amplification | unknown | Phase 2 | 43 | Peking UniversityOTHER | 1 | Jul 13, 2021 | clinicaltrials |
| NCT03766178 | Study of Anti-PD-1 Antibody SHR-1210 Plus Nimotuzumab in the Treatment of Advanced Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 45 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Jul 7, 2021 | clinicaltrials |
| NCT04275986 | Concurrent Chemoradiotherapy After Endoscopic Resection for Stage I Esophageal Carcinoma | unknown | Phase 2 | 56 | Chinese Academy of Medical SciencesOTHER | 1 | Jul 7, 2021 | clinicaltrials |
| NCT03713749 | Robotic-assisted Esophagectomy vs. Video-Assisted Thoracoscopic Esophagectomy(REVATE) Trial | unknown | N/A | 212 | Chang Gung Memorial HospitalOTHER | 1 | Jul 1, 2021 | clinicaltrials |
| NCT00487695 | Confocal Endomicroscopy for Barrett's Esophagus(CEBE) | completed | Phase 3 | 46 | Johns Hopkins UniversityOTHER | 1 | Jun 22, 2021 | clinicaltrials |
| NCT04851132 | Radiotherapy Plus Durvalumab in Elderly Esophageal Squamous Cell Carcinoma | unknown | N/A | 33 | Chinese Academy of Medical SciencesOTHER | 1 | Jun 22, 2021 | clinicaltrials |
| NCT04669951 | Urokinase-type Plasminogen Activator Receptor and Gastroesophageal Cancer | completed | N/A | 100 | Michael Patrick AchiamOTHER | 1 | Jun 3, 2021 | clinicaltrials |
| NCT04894149 | Prehabilitation and Rehabilitation for Patients With Oesophageal Cancer(PRESO) | unknown | N/A | 25 | Gabriella Alexandersson von DöbelnOTHER | 1 | May 20, 2021 | clinicaltrials |
| NCT00003487 | Antineoplaston Therapy in Treating Patients With Cancer of the Esophagus | terminated | Phase 2 | 8 | Burzynski Research InstituteOTHER | 1 | May 14, 2021 | clinicaltrials |
| NCT04464967 | Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers | withdrawn | Phase 1 / Phase 2 | 0 | NKGen Biotech, Inc.INDUSTRY | 0 | May 12, 2021 | clinicaltrials |
| NCT04866381 | An Exploratory Clinical Study of SHR6390 and SHR1020 in the Treatment of Esophageal Squamous Cell Carcinoma After Progression on PD-1 Antibody | unknown | Phase 2 | 87 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Apr 29, 2021 | clinicaltrials |
| NCT02326779 | Low-dose Aspirin Therapy for Esophageal Cancer | withdrawn | Phase 3 | 0 | Zhejiang UniversityOTHER | 0 | Apr 27, 2021 | clinicaltrials |
| NCT03151642 | A PILOT STUDY OF DIFFUSION WEIGHTED MRI TO ASSESS ESOPHAGEAL TUMOR RESONSE TO NEOADJUVANT CHEMORADIATION | completed | — | 11 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Apr 26, 2021 | clinicaltrials |
| NCT01077999 | Chemoradiation and Panitumumab for Esophageal Cancer | completed | Phase 2 | 78 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Apr 21, 2021 | clinicaltrials |
| NCT04843397 | Diagnostic Performance Indicators in Upper GI Endoscopy:PROSPERO Study(PROSPERO) | unknown | — | 1,000 | University of CambridgeOTHER | 0 | Apr 15, 2021 | clinicaltrials |
| NCT01217060 | Trimodality Management of T1b Esophageal Cancers | completed | Phase 1 / Phase 2 | 4 | M.D. Anderson Cancer CenterOTHER | 1 | Apr 13, 2021 | clinicaltrials |
| NCT03585530 | Raltitrexed Concurrent With Radiotherapy for Elderly Chinese Patients With Squamous Cell Carcinoma of Esophagus | unknown | Phase 2 | 32 | Huai'an First People's HospitalOTHER | 1 | Apr 6, 2021 | clinicaltrials |
| NCT02128243 | Trial of S-1 Maintenance Therapy in Metastatic Esophagogastric Cancer(MATEO) | completed | Phase 2 | 242 | AIO-Studien-gGmbHOTHER | 1 | Mar 26, 2021 | clinicaltrials |
| NCT04818476 | Outcomes of Endoscopically Resected High-risk Mucosal and Low- and High-risk Submucosal Adenocarcinoma Arising in Barrett's Esophagus | unknown | — | 1,000 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 7 | Mar 26, 2021 | clinicaltrials |
| NCT04813406 | Study of Anlotinib Plus Sintilimab in the Treatment of Advanced Esophageal Squamous Cell Carcinoma | unknown | N/A | 53 | Henan Provincial People's HospitalOTHER | 0 | Mar 24, 2021 | clinicaltrials |
| NCT03619317 | Impact of Cancer Therapy on Myocardial Function in Patients With Esophagus Cancer(Heartcheck) | unknown | — | 56 | Aarhus University Hospital SkejbyOTHER | 1 | Mar 23, 2021 | clinicaltrials |
| NCT02272699 | Neoadjuvant Treatment of Nimotuzumab With Chemotherapy or Radiotherapy in Resectable Esophageal Squamous Cell Carcinoma | withdrawn | Phase 2 / Phase 3 | 0 | Peking UniversityOTHER | 1 | Mar 18, 2021 | clinicaltrials |
| NCT02645864 | Apatinib and Irinotecan Combination Treatment in Esophageal Squamous Cell Carcinoma | completed | Phase 1 | 12 | Peking UniversityOTHER | 1 | Mar 18, 2021 | clinicaltrials |
| NCT03535207 | High-dose Intensity Modulated Radiotherapy and Concurrent Chemotherapy in Esophageal Cancer | unknown | N/A | 50 | Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 1 | Mar 18, 2021 | clinicaltrials |
| NCT03936179 | High Dose PET/CT-guided Intensity Modulated Radiotherapy and Concurrent Chemotherapy in Esophageal Cancer | unknown | N/A | 50 | Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 1 | Mar 18, 2021 | clinicaltrials |
| NCT04804410 | Dielectric Properties of Matched Tissue Samples From Thoracic Malignancies and Corresponding Normal Tissues | unknown | N/A | 30 | University of Maryland, BaltimoreOTHER | 0 | Mar 18, 2021 | clinicaltrials |
| NCT03541629 | Audit of the Spanish EURECCA Esophagogastric Cancer Registry | completed | — | 1,839 | Parc de Salut MarOTHER | 1 | Mar 16, 2021 | clinicaltrials |
| NCT04797507 | SHR-1210 in Combination With Anlotinib in Patients With Advanced or Metastatic Esophageal Squamous Cell Cancer | unknown | Phase 2 | 33 | Peking Union Medical College HospitalOTHER | 0 | Mar 15, 2021 | clinicaltrials |
| NCT03719716 | Early Support in Primary Care for People Starting Treatment for Cancer(GI-ACP) | completed | N/A | 46 | NHS LothianOTHER_GOV | 1 | Mar 9, 2021 | clinicaltrials |
| NCT04086901 | Dose Escalated Adaptive RadioTherapy in Definitive Chemo-radiotherapy for Esophageal Cancer(DART) | terminated | N/A | 3 | University of AarhusOTHER | 1 | Mar 9, 2021 | clinicaltrials |
| NCT02864355 | Does Perioperative Goal Directed Therapy Using Flotrac Improve Outcomes in Esophagectomy Patients | terminated | N/A | 53 | Medical University of South CarolinaOTHER | 1 | Mar 2, 2021 | clinicaltrials |
Data updated 23 days agoSource updated Sep 8, 2021source: clinicaltrials