Cancer
Malignant Esophageal Neoplasm
CI-CAN-00001127Explore in graph →
Top-level518 active trials6 approved drugs12 evidence items
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Cancer
CI-CAN-00001127Explore in graph →
Clinical trials
1,926 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (169)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01366833 | Optimal Management of Malignant Dysphagia | terminated | N/A | 3 | McGill University Health Centre/Research Institute of the McGill University Health CentreOTHER | 1 | Oct 23, 2023 | clinicaltrials |
| NCT04424641 | A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors | terminated | Phase 1 / Phase 2 | 48 | GenmabINDUSTRY | 4 | Jul 25, 2023 | clinicaltrials |
| NCT02530437 | Taladegib, Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Localized Esophageal or Gastroesophageal Junction Cancer | terminated | Phase 1 / Phase 2 | 7 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 10, 2023 | clinicaltrials |
| NCT00551759 | Chemotherapy, Radiation Therapy, and Cetuximab Followed by Surgery, Docetaxel, and Cetuximab in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer | terminated | Phase 2 | 22 | Eastern Cooperative Oncology GroupNETWORK | 1 | Jul 3, 2023 | clinicaltrials |
| NCT03233724 | Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal Carcinomas | terminated | Phase 1 / Phase 2 | 9 | National Cancer Institute (NCI)NIH | 1 | May 31, 2023 | clinicaltrials |
| NCT03385343 | Staging of Superficial EAC Using VLE | terminated | N/A | 30 | Mayo ClinicOTHER | 1 | May 9, 2023 | clinicaltrials |
| NCT03240679 | Endoscopic Mucosal Resection and Cellular Matrix | terminated | N/A | 3 | Mayo ClinicOTHER | 1 | Feb 6, 2023 | clinicaltrials |
| NCT03251417 | Apatinib and Irinotecan Combination Treatment in Unresectable or Metastatic Esophageal Squamous Cell Carcinoma | terminated | Phase 2 | 11 | Peking UniversityOTHER | 1 | Feb 1, 2023 | clinicaltrials |
| NCT04510285 | A Single-Arm Pilot Study of Adjuvant Pembrolizumab Plus Trastuzumab in HER2+ Esophagogastric Tumors With Persistent Circulating Tumor DNA Following Curative Resection | terminated | Phase 2 | 1 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 1, 2023 | clinicaltrials |
| NCT04077372 | Assessment of a Serious Illness Conversation Guide (SICG) in Advanced Gastro-Intestinal Cancers | terminated | N/A | 12 | Stanford UniversityOTHER | 1 | Jan 27, 2023 | clinicaltrials |
| NCT03570996 | A Trial Comparing Transversus Abdominis Plane Catheter Versus Epidural After Esophagectomy | terminated | N/A | 38 | Swedish Medical CenterOTHER | 1 | Jan 23, 2023 | clinicaltrials |
| NCT04642690 | Nitrates and IL-8 in Barrett's Esophagus | terminated | — | 9 | Mayo ClinicOTHER | 1 | Dec 15, 2022 | clinicaltrials |
| NCT04060342 | GB1275 Monotherapy and in Combination With an Anti-PD1 Antibody in Patients With Specified Advanced Solid Tumors or in Combination With Standard of Care in Patients With Metastatic Pancreatic Adenocarcinoma | terminated | Phase 1 | 61 | GB006, Inc., a wholly owned subsidiary of Gossamer Bio, Inc.INDUSTRY | 2 | Aug 18, 2022 | clinicaltrials |
| NCT00573131 | Efficacy and Safety of OncoGel™ Added to Chemotherapy and Radiation Before Surgery in Subjects With Esophageal Cancer | terminated | Phase 2 | 137 | Boston Scientific CorporationINDUSTRY | 4 | Jun 22, 2022 | clinicaltrials |
| NCT03278626 | Immune Checkpoint Therapy With Nivolumab Esophageal Squamous Cell Carcinoma | terminated | Phase 1 / Phase 2 | 12 | NYU Langone HealthOTHER | 1 | Mar 28, 2022 | clinicaltrials |
| NCT01868139 | Spray Cryotherapy for Esophageal Cancer (ICE-CANCER)(ICE-CANCER) | terminated | N/A | 1 | University of Maryland, BaltimoreOTHER | 1 | Mar 7, 2022 | clinicaltrials |
| NCT01445327 | Predictors of Tumor Response and of Radiation Therapy Side Effects in Patients With Gastrointestinal Cancers | terminated | — | 9 | National Cancer Institute (NCI)NIH | 1 | Feb 1, 2022 | clinicaltrials |
| NCT01806649 | BKM120 in Esophageal Squamous Cell Carcinoma After Failure of First Line Chemotherapy | terminated | Phase 2 | 5 | Prince of Songkla UniversityOTHER | 1 | Oct 11, 2021 | clinicaltrials |
| NCT00003487 | Antineoplaston Therapy in Treating Patients With Cancer of the Esophagus | terminated | Phase 2 | 8 | Burzynski Research InstituteOTHER | 1 | May 14, 2021 | clinicaltrials |
| NCT04086901 | Dose Escalated Adaptive RadioTherapy in Definitive Chemo-radiotherapy for Esophageal Cancer(DART) | terminated | N/A | 3 | University of AarhusOTHER | 1 | Mar 9, 2021 | clinicaltrials |
| NCT02864355 | Does Perioperative Goal Directed Therapy Using Flotrac Improve Outcomes in Esophagectomy Patients | terminated | N/A | 53 | Medical University of South CarolinaOTHER | 1 | Mar 2, 2021 | clinicaltrials |
| NCT00064259 | A Phase I/II Study of Oblimersen Plus Cisplatin and Fluorouracil in Gastric & Esophageal Junction Cancer | terminated | Phase 1 / Phase 2 | 15 | National Cancer Institute (NCI)NIH | 1 | Feb 17, 2021 | clinicaltrials |
| NCT02757391 | CD8+ T Cell Therapy and Pembrolizumab in Treating Patients With Metastatic Gastrointestinal Tumors | terminated | Phase 1 | 1 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 30, 2020 | clinicaltrials |
| NCT02297607 | Routine Post-Operative Supplemental Nutrition | terminated | N/A | 30 | University of MichiganOTHER | 1 | Aug 27, 2020 | clinicaltrials |
| NCT00006472 | Combination Chemotherapy Plus Radiation Therapy Followed By Surgery in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer | terminated | Phase 2 | 4 | Medstar Health Research InstituteOTHER | 1 | Aug 18, 2020 | clinicaltrials |
| NCT01249443 | Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV Infection | terminated | Phase 1 | 17 | AIDS Malignancy ConsortiumNETWORK | 1 | Jul 29, 2020 | clinicaltrials |
| NCT02017600 | A Phase II Trial of Induction Chemotherapy With ND-420, Cisplatin and Fluorouracil Followed by Surgery in the Treatment of Patients With Localized Squamous Cell Carcinoma of the Esophagus | terminated | Phase 2 | 48 | Nang Kuang Pharmaceutical Co., Ltd.INDUSTRY | 1 | May 20, 2020 | clinicaltrials |
| NCT03206125 | NCI UNC Project ESCC | terminated | — | 648 | National Cancer Institute (NCI)NIH | 1 | May 20, 2020 | clinicaltrials |
| NCT00539617 | Chemotherapy & Erlotinib in Treating Patients w/ Esophageal or Gastroesophageal Cancer That Cannot Be Removed by Surgery | terminated | Phase 2 | 7 | University of California, San FranciscoOTHER | 1 | Mar 23, 2020 | clinicaltrials |
| NCT01143545 | Pilot Study of Allogeneic Tumor Cell Vaccine With Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thymic Neoplasms, and Malignant Pleural Mesotheliomas | terminated | Phase 1 | 10 | National Cancer Institute (NCI)NIH | 1 | Mar 3, 2020 | clinicaltrials |
| NCT01624090 | Mithramycin for Lung, Esophagus, and Other Chest Cancers | terminated | Phase 2 | 16 | National Cancer Institute (NCI)NIH | 1 | Dec 30, 2019 | clinicaltrials |
| NCT00585117 | Pilot Study of (61)CuATSM-PET Imaging in Cancer Patients | terminated | N/A | 9 | University of Wisconsin, MadisonOTHER | 1 | Dec 13, 2019 | clinicaltrials |
| NCT01258868 | Tumor Cell Vaccines With ISCOMATRIX Adjuvant and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers and Malignant Pleural Mesotheliomas | terminated | Phase 1 | 44 | National Cancer Institute (NCI)NIH | 1 | Dec 3, 2019 | clinicaltrials |
| NCT02318901 | Pembrolizumab and Monoclonal Antibody Therapy in Advanced Cancer(PembroMab) | terminated | Phase 1 / Phase 2 | 16 | Western Regional Medical CenterOTHER | 1 | Oct 21, 2019 | clinicaltrials |
| NCT03211780 | Use of Intra-Operative Shear Wave Ultrasound Vibrometry for Characterization of Esophageal Malignant Tumors | terminated | N/A | 3 | Mayo ClinicOTHER | 1 | Oct 4, 2019 | clinicaltrials |
| NCT02062632 | Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapy | terminated | Phase 2 | 5 | Mayo ClinicOTHER | 1 | Oct 1, 2019 | clinicaltrials |
| NCT02457299 | Esophagectomy With or Without Prior Ischemic Gastric Preconditioning | terminated | N/A | 1 | Endeavor HealthOTHER | 1 | Aug 5, 2019 | clinicaltrials |
| NCT01248299 | Benefit of Chemotherapy Over Best Supportive Care in Metastatic and Squamous Cell-type Esophageal Cancer.(E-DIS) | terminated | Phase 2 | 105 | Centre Oscar LambretOTHER | 1 | May 16, 2019 | clinicaltrials |
| NCT03122548 | Safety and Efficacy of CRS-207 With Pembrolizumab in Gastric, Gastroesophageal Junction or Esophageal Cancers | terminated | Phase 2 | 5 | Aduro Biotech, Inc.INDUSTRY | 1 | Apr 4, 2019 | clinicaltrials |
| NCT02547142 | Early Integration of Palliative Care in Esophageal Cancer Patients | terminated | N/A | 12 | McMaster UniversityOTHER | 1 | Mar 14, 2019 | clinicaltrials |
| NCT01372202 | CHFR Methylation Status Esophageal Cancer Study(J10130) | terminated | Phase 2 | 31 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Jan 25, 2019 | clinicaltrials |
| NCT02221245 | Wnt, Notch and Hedgehog Activity in Chemo-Naive Tumors Collected During Staging of Esophageal Cancer Patients | terminated | — | 24 | University of MiamiOTHER | 1 | Jan 15, 2019 | clinicaltrials |
| NCT00493025 | Paclitaxel, Cisplatin, Gefitinib, and Radiation Therapy Followed by Surgery and Gefitinib in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction That Can Be Removed By Surgery | terminated | Phase 2 | 19 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Dec 6, 2018 | clinicaltrials |
| NCT01446874 | Prevention of Post-operative Pneumonia (POPP)(POPP) | terminated | Phase 2 / Phase 3 | 150 | Washington University School of MedicineOTHER | 1 | Nov 8, 2018 | clinicaltrials |
| NCT03223662 | Metabolomic and BH3 Profiling of Esophageal Cancers: Identification of Novel Assessment Methods of Treatment Response for Precision Therapy | terminated | Phase 2 | 2 | National Cancer Institute (NCI)NIH | 1 | Oct 30, 2018 | clinicaltrials |
| NCT02234180 | Regorafenib in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction Who Have Completed Chemoradiation Therapy and Surgery | terminated | Phase 2 | 3 | Academic and Community Cancer Research UnitedOTHER | 1 | Oct 17, 2018 | clinicaltrials |
| NCT01471249 | Quality of Life and Dysphagia Following Palliative Stenting in Esophageal Cancer | terminated | — | 13 | Centre hospitalier de l'Université de Montréal (CHUM)OTHER | 1 | Sep 17, 2018 | clinicaltrials |
| NCT02358863 | Molecularly Tailored Therapy for Patients With Metastatic Cancer of the Esophagus and Stomach(mEGA) | terminated | N/A | 13 | Georgetown UniversityOTHER | 1 | Sep 6, 2018 | clinicaltrials |
| NCT01608464 | Pre-op Chemo-RT w/CDDP/5FU vs Chemo w/ Docetaxel/Irinotecan in PET Non Responder Resectable Esophagus Cancer | terminated | Phase 2 | 170 | King Faisal Specialist Hospital & Research CenterOTHER | 1 | Aug 10, 2018 | clinicaltrials |
| NCT01738633 | Quality of Life After Esophagectomy for Cancer - Step 2 | terminated | N/A | 80 | University of PadovaOTHER | 1 | May 23, 2018 | clinicaltrials |
Data updated 22 days agoSource updated Oct 23, 2023source: clinicaltrials