Cancer Family
Malignant Digestive System Neoplasm
CI-CAN-00000229Explore in graph →
4,263 active trials43 approved drugs556 evidence items
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Cancer Family
CI-CAN-00000229Explore in graph →
Clinical trials
19,110 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (2,003)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06126406 | Clinical Study of CEA Targeting Chimeric Antigen Receptor T Lymphocytes（CAR-T） for CEA Positive Advanced Malignant Solid Tumors | recruiting | Phase 1 | 60 | Chongqing Precision Biotech Co., LtdINDUSTRY | 1 | Nov 13, 2023 | clinicaltrials |
| NCT04575363 | RPSA as a Potential Prognostic Biomarker of Pancreatic Cancer(PaCaBioMarkeR) | recruiting | N/A | 90 | CHU de ReimsOTHER | 1 | Nov 9, 2023 | clinicaltrials |
| NCT06010862 | Clinical Study of CEA-targeted CAR-T Therapy for CEA-positive Advanced/Metastatic Malignant Solid Tumors | recruiting | Phase 1 | 36 | Chongqing Precision Biotech Co., LtdINDUSTRY | 1 | Nov 8, 2023 | clinicaltrials |
| NCT06121700 | Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancer(Miracle-G) | recruiting | Phase 2 | 55 | Fudan UniversityOTHER | 1 | Nov 8, 2023 | clinicaltrials |
| NCT06122493 | Optimization of Treatment Strategy for Unresectable cN3 Esophageal Squamous Cell Carcinoma | recruiting | Phase 2 | 48 | Ruijin HospitalOTHER | 1 | Nov 8, 2023 | clinicaltrials |
| NCT05444478 | Microwave Ablation Simultaneously Combined With Lenavatinib for Recurrent Hepatocellular Carcinoma | recruiting | N/A | 274 | Sun Yat-sen UniversityOTHER | 1 | Nov 7, 2023 | clinicaltrials |
| NCT05494060 | XELOX Combined With Anlotinib and Penpulimab vs XELOX as Adjuvant Therapy in ctDNA Positive Gastric and Esophagogastric Junction Adenocarcinoma(EXPLORING) | recruiting | Phase 2 | 80 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Nov 7, 2023 | clinicaltrials |
| NCT06118762 | Clinical Study of Fruquintinib Combined With Raltitrexed in the Treatment of Metastatic Colorectal Cancer | recruiting | Phase 4 | 30 | The First Affiliated Hospital of Nanchang UniversityOTHER | 1 | Nov 7, 2023 | clinicaltrials |
| NCT06116019 | Online Adaptive Radiotherapy Using a Novel Linear Accelerator (ETHOS)(ART-02) | recruiting | — | 649 | Charite University, Berlin, GermanyOTHER | 1 | Nov 3, 2023 | clinicaltrials |
| NCT05752812 | The HELPP Score: A Pretreatment Score to Predict Survival in Pancreatic Cancer | recruiting | — | 1,500 | Medical University of ViennaOTHER | 1 | Oct 27, 2023 | clinicaltrials |
| NCT06104241 | BGT007 Cells for the Treatment of Refractory Digestive System Tumors | recruiting | Early Phase 1 | 14 | The Affiliated Hospital of Xuzhou Medical UniversityOTHER | 1 | Oct 27, 2023 | clinicaltrials |
| NCT05916261 | Personalized Tumor Vaccines and Pabolizumab in Patients With Advanced Pancreatic Cancer | recruiting | Early Phase 1 | 54 | Ruijin HospitalOTHER | 1 | Oct 26, 2023 | clinicaltrials |
| NCT05985109 | KN 046 Plus Regorafenib in MSS Metastatic Colorectal Cancer | recruiting | Phase 2 | 98 | Peking University Cancer Hospital & InstituteOTHER | 1 | Oct 26, 2023 | clinicaltrials |
| NCT06099821 | KN046 Plus Regorafenib or Apatinib in MSI-H Digestive System Cancers Resistant to PD-1/PD-L1 Blockade | recruiting | Phase 2 | 39 | Peking University Cancer Hospital & InstituteOTHER | 1 | Oct 26, 2023 | clinicaltrials |
| NCT06102759 | Adebrelimab and Fruquintinib Combined With Paclitaxel/Albumin Paclitaxel for Advanced Gastric Cancer After PD-1 Antibody Failed | recruiting | — | 30 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Oct 26, 2023 | clinicaltrials |
| NCT06102772 | Adebrelimab and Fruquintinib Combined With Paclitaxel/Albumin Paclitaxel for Advanced Gastric Cancer | recruiting | — | 30 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Oct 26, 2023 | clinicaltrials |
| NCT06102785 | Fruquintinib Combined With TAS102 for Advanced Gastric Cancer | recruiting | — | 30 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Oct 26, 2023 | clinicaltrials |
| NCT05551416 | The EpiGASTRIC/EDGAR Project: New Strategies for the Early Detection and Prevention of Gastric Cancer | recruiting | — | 1,200 | EDUARDO ALBENIZOTHER | 1 | Oct 24, 2023 | clinicaltrials |
| NCT03964753 | Neoadjuvant Therapy With Nab-paclitaxel and Cisplatin for Locally Advanced Esophageal Squamous Cell Carcinoma(NTNC) | recruiting | Phase 2 | 202 | Hebei Medical University Fourth HospitalOTHER | 1 | Oct 10, 2023 | clinicaltrials |
| NCT06070740 | First- Line Treatment With Durvalumab Plus XELOX Chemotherapy in Advanced Gastrointestinal Neuroendocrine Carcinoma | recruiting | Phase 2 | 22 | Peking Union Medical College HospitalOTHER | 1 | Oct 6, 2023 | clinicaltrials |
| NCT06068023 | The ADAPTA Study: ADjuvant chemotherAPy After Curative Intent resecTion of Ampullary Cancer.(ADAPTA) | recruiting | — | 400 | Fondazione Poliambulanza Istituto OspedalieroOTHER | 1 | Oct 5, 2023 | clinicaltrials |
| NCT06065891 | Para-aortic Lymph Node Metastasis in Resectable Pancreatic Cancer(PALN) | recruiting | N/A | 300 | Jon UnossonOTHER | 2 | Oct 4, 2023 | clinicaltrials |
| NCT06035250 | AI Prediction of Gastric Cancer Response to Neoadjuvant Chemotherapy | recruiting | — | 200 | Chinese Academy of SciencesOTHER_GOV | 2 | Sep 28, 2023 | clinicaltrials |
| NCT06056336 | Perioperative Tislelizumab Plus Chemotherapy for Resectable Thoracic Oesophageal Squamous Cell Carcinoma | recruiting | Phase 2 | 73 | Guo XufengOTHER | 1 | Sep 28, 2023 | clinicaltrials |
| NCT05450029 | Neoadjuvant Chemoradiotherapy Plus Sintilimab for Intermediate/High Immunoscore Locally Advanced Rectal Cancer(SILAR) | recruiting | Phase 2 | 51 | Yanhong DengOTHER | 1 | Sep 26, 2023 | clinicaltrials |
| NCT06044506 | Autologous Natural Killer Cell Therapy for Hepatocellular Carcinoma | recruiting | Phase 1 | 3 | Dr Cipto Mangunkusumo General HospitalOTHER | 1 | Sep 26, 2023 | clinicaltrials |
| NCT06055010 | Improving Pancreatic Cancer Care by the Use of Computational Science and Technology(IMPACT) | recruiting | — | 5,000 | UMC UtrechtOTHER | 1 | Sep 26, 2023 | clinicaltrials |
| NCT05438836 | Re-optimization Based Online Adaptive Radiotherapy of Anal Cancer(ROAR-A) | recruiting | — | 205 | Herlev HospitalOTHER | 1 | Sep 25, 2023 | clinicaltrials |
| NCT04616495 | Liver Transplantation in Patients With Unresectable Colorectal Liver Metastases(TRASMETIR) | recruiting | — | 30 | Hospital Universitario La FeOTHER | 1 | Sep 22, 2023 | clinicaltrials |
| NCT06042998 | A Multicenter, RCT Study of the Clinical Efficacy of Robotic and Laparoscopic Gastrectomy in Neoadjuvant Gastric Cancer(CLASS14) | recruiting | N/A | 588 | The Affiliated Hospital of Qingdao UniversityOTHER | 1 | Sep 21, 2023 | clinicaltrials |
| NCT06043466 | A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid Tumors | recruiting | Phase 1 | 30 | Chongqing Precision Biotech Co., LtdINDUSTRY | 1 | Sep 21, 2023 | clinicaltrials |
| NCT06043921 | Multicenter Study of Circulating Tumor DNA in Patients With Pancreatic Cancer Using a Personalized Panel(ARTEMIS-PC) | recruiting | — | 150 | Invitae CorporationINDUSTRY | 1 | Sep 21, 2023 | clinicaltrials |
| NCT06043999 | Salvage Chemotherapy Versus Total Mesorectal Resection for Local Resection Rectal Cancer Patients | recruiting | N/A | 392 | Sun Yat-sen UniversityOTHER | 1 | Sep 21, 2023 | clinicaltrials |
| NCT05994859 | SIRT for Potentially Resectable HCC | recruiting | N/A | 35 | Second Affiliated Hospital of Guangzhou Medical UniversityOTHER | 1 | Sep 14, 2023 | clinicaltrials |
| NCT06037902 | CPAP for Esophageal Cancer With Radiotherapy(TROS-7) | recruiting | N/A | 44 | Sheba Medical CenterOTHER_GOV | 1 | Sep 14, 2023 | clinicaltrials |
| NCT06028724 | A Study on the Prevalence of Clinically Useful Mutations in Solid Tumor Characterized by Next Generation Sequencing Methods on Liquid Biopsy Analysis (POPCORN)(POPCORN) | recruiting | — | 782 | Centro di Riferimento Oncologico - AvianoOTHER | 1 | Sep 13, 2023 | clinicaltrials |
| NCT05264896 | Perioperative FLOT vs Adjuvant XELOX for CA Stomach | recruiting | Phase 3 | 110 | Chinese University of Hong KongOTHER | 1 | Sep 7, 2023 | clinicaltrials |
| NCT04743479 | Artificial Intelligence-based Early Screening of Pancreatic Cancer and High Risk Tracing (ESPRIT-AI)(ESPRIT-AI) | recruiting | — | 5,000 | Changhai HospitalOTHER | 1 | Sep 1, 2023 | clinicaltrials |
| NCT05962502 | Cetuximab Plus Irinotecan in Patients With NeoRAS Wild-type Metastatic Colorectal Cancer In Third-line Therapy | recruiting | Phase 2 | 54 | Sun Yat-sen UniversityOTHER | 1 | Aug 31, 2023 | clinicaltrials |
| NCT05047510 | GPC3 Targeted Fluorescence Image Guided Surgery of Hepatocellular Carcinoma | recruiting | N/A | 60 | Chinese Academy of SciencesOTHER_GOV | 1 | Aug 30, 2023 | clinicaltrials |
| NCT05336539 | A Community Population Screening Cohort Study Based on Polygene Methylation Detection for Colorectal Cancer in Yangzhou | recruiting | — | 80,000 | Singlera Genomics Inc.INDUSTRY | 1 | Aug 29, 2023 | clinicaltrials |
| NCT05956847 | The Role of Extracellular DNA (ecDNA) in the Occurrence and Development of Gastric | recruiting | — | 1,000 | Xijing HospitalOTHER | 1 | Aug 29, 2023 | clinicaltrials |
| NCT03637569 | The Relationship Between Triceps Skinfold and Overall Survival of Pancreas, Bile Duct, Gallbladder Cancer | recruiting | — | 1,000 | Samsung Medical CenterOTHER | 1 | Aug 25, 2023 | clinicaltrials |
| NCT05502198 | Relevance of Sarcopenia in Advanced Liver Disease(ACCESS-ESLD) | recruiting | — | 150 | Linkoeping UniversityOTHER_GOV | 1 | Aug 24, 2023 | clinicaltrials |
| NCT05879783 | Optical Biopsy for Peritoneal Nodules in Colorectal Patients | recruiting | N/A | 278 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Aug 23, 2023 | clinicaltrials |
| NCT06006650 | Neoadjuvant Therapy for Stage II-IVA Resectable Esophageal Squamous Cell | recruiting | Phase 2 | 114 | Tang-Du HospitalOTHER | 1 | Aug 23, 2023 | clinicaltrials |
| NCT05984342 | Adjuvant Chemotherapy in Combination With Tislelizumab in Lymph Node-Positive Esophageal Squamous Cell Carcinoma | recruiting | Phase 1 | 50 | Affiliated Cancer Hospital of Shantou University Medical CollegeOTHER | 1 | Aug 9, 2023 | clinicaltrials |
| NCT05984485 | The Efficacy of Primary Total Mesorectal Excision (TME) Surgery Versus Neoadjuvant Chemotherapy Combined With TME Surgery in Low-risk Locally Advanced Rectal Cancer(TaLaR-02) | recruiting | Phase 3 | 766 | Sun Yat-sen UniversityOTHER | 1 | Aug 9, 2023 | clinicaltrials |
| NCT05869474 | Implantation of iodine125-Seeds Combined With Chemotherapy in the Treatment of Metastatic Pancreatic Carcinoma | recruiting | N/A | 206 | Changhai HospitalOTHER | 1 | Aug 4, 2023 | clinicaltrials |
| NCT05734300 | The "SPARCOL" Study | recruiting | N/A | 48 | Zealand University HospitalOTHER | 1 | Jul 25, 2023 | clinicaltrials |
Data updated 24 days agoSource updated Nov 13, 2023source: clinicaltrials