Cancer Family
Malignant Digestive System Neoplasm
CI-CAN-00000229Explore in graph →
4,262 active trials43 approved drugs556 evidence items
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Cancer Family
CI-CAN-00000229Explore in graph →
Clinical trials
19,101 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (2,000)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07769853 | Iparomlimab and Tuvonralimab Combined With Chemotherapy and Bevacizumab as Neoadjuvant Therapy for Locally Advanced Rectal Cancer(IT-CABLE) | not yet recruiting | N/A | 56 | Zhejiang UniversityOTHER | 0 | Sep 15, 2026 | clinicaltrials |
| NCT07819604 | Serplulimab Combined With CAPOX and Bevacizumab as Neoadjuvant Therapy for Locally Advanced Colorectal Cancer | not yet recruiting | Phase 2 | 85 | Xijing HospitalOTHER | 0 | Sep 15, 2026 |
| clinicaltrials |
| NCT07404228 | Multidimensional Study Designed to Develop a Methodological Framework Based on MRI Data to Predict Pathological Complete Response (pCR) in Patients With Locally Advanced Rectal Cancer After Neoadjuvant Treatment(RESTAGE) | not yet recruiting | — | 115 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Sep 14, 2026 | clinicaltrials |
| NCT07817602 | Real-world Evaluation of Different Endoscopic Biliary Drainage Techniques in Patients With Jaundice of Biliopancreatic Malignant Origin(PROBILEUS) | not yet recruiting | — | 300 | Centre Hospitalier Universitaire de NīmesOTHER | 1 | Sep 14, 2026 | clinicaltrials |
| NCT07818070 | A Trial of ONO-4578 Versus Placebo in Combination With Nivolumab and Chemotherapy in Participants With Gastric Cancer, Esophagogastric Junction Cancer, or Esophageal Adenocarcinoma | not yet recruiting | Phase 3 | 600 | Ono Pharmaceutical Co., Ltd.INDUSTRY | 0 | Sep 14, 2026 | clinicaltrials |
| NCT07819019 | A Phase II Study of Irinotecan Liposome Plus Fruquintinib and Sintilimab in Second-Line PD-L1-Positive Advanced Gastric Cancer | not yet recruiting | Phase 2 | 20 | Cancer Hospital Chinese Academy of Medical Science, Shenzhen CenterOTHER | 0 | Sep 14, 2026 | clinicaltrials |
| NCT04381130 | A Phase I/IIa Study of EF-009 in Patients With Pancreatic Cancer | not yet recruiting | Phase 1 / Phase 2 | 30 | Everfront Biotech Co., Ltd.INDUSTRY | 0 | Sep 11, 2026 | clinicaltrials |
| NCT07799740 | Examination of Rectal Blood Supply During Rectal Cancer Surgery Using Laser Speckle Contrast Imaging(LIRA) | not yet recruiting | N/A | 100 | University of AarhusOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT07814586 | Prognostic Evaluation and Systematic Re-Assessment of Cholangiocarcinoma Therapy(Re-ACT) | not yet recruiting | — | 900 | Karolinska University HospitalOTHER | 0 | Sep 11, 2026 | clinicaltrials |
| NCT07814859 | Retlirafusp Alfa Combined With Famitinib, Nab-Paclitaxel and Gemcitabine for First-Line Treatment of Patients With Unresectable Pancreatic Cancer | not yet recruiting | Phase 2 | 88 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT07815054 | Efficacy Evaluation of Microwave Ablation Assisted by Diaphragm Hydrodissection for Hepatocellular Carcinoma and Comparative Analysis With Surgical | not yet recruiting | — | 200 | The First Hospital of Jilin UniversityOTHER | 0 | Sep 11, 2026 | clinicaltrials |
| NCT07815093 | Multimodal Artificial Intelligence for Non-Invasive Colorectal Cancer Screening Based on Holographic Biology | not yet recruiting | — | 11,000 | Xiuli ZuoOTHER | 0 | Sep 11, 2026 | clinicaltrials |
| NCT07733427 | Evaluating the Effectiveness of AIT in the Treatment of Pain Related to Pancreatic Cancer(PIT) | not yet recruiting | N/A | 40 | Clinique BizetOTHER | 1 | Sep 10, 2026 | clinicaltrials |
| NCT07811453 | Liver Transplantation for Non-Resectable Colorectal Liver Metastases Without Local Treatment Options(GTO-001) | not yet recruiting | N/A | 260 | Charite University, Berlin, GermanyOTHER | 1 | Sep 10, 2026 | clinicaltrials |
| NCT07813572 | ZG005 Plus Bevacizumab vs Sintilimab Plus Bevacizumab as First-Line Therapy for Advanced Hepatocellular | not yet recruiting | Phase 3 | 600 | Suzhou Zelgen Biopharmaceuticals Co.,LtdINDUSTRY | 1 | Sep 10, 2026 | clinicaltrials |
| NCT07814066 | A Multicenter, Open-label, Phase II Umbrella Study to Evaluate the Efficacy and Safety of the Investigational Product in Participants With Advanced or Metastatic Pancreatic Cancer | not yet recruiting | Phase 2 | 30 | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.INDUSTRY | 0 | Sep 10, 2026 | clinicaltrials |
| NCT07814248 | A Phase 1, First-in-Human (FIH), Open-Label, Dose-Escalation and Dose Expansion Study of the Peptide Drug Conjugate (PDC), TS-104, as a Monotherapy in Subjects With Select Advanced Solid Tumors | not yet recruiting | Phase 1 | 74 | TwoStep Therapeutics, Inc.INDUSTRY | 0 | Sep 10, 2026 | clinicaltrials |
| NCT07814326 | Feasibility of the Loop Brush EUS-FNA for Characterization of Pancreatic Cysts: Pilot Clinical Investigation(PCLoop-Pilot) | not yet recruiting | N/A | 8 | Urban ArneloOTHER_GOV | 1 | Sep 10, 2026 | clinicaltrials |
| NCT05039892 | Efficacy and Safety of 3D185 Monotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Cholangiocarcinoma | not yet recruiting | Phase 2 | 50 | 3D Medicines (Beijing) Co., Ltd.INDUSTRY | 0 | Sep 9, 2026 | clinicaltrials |
| NCT07805369 | A Phase 1 Study of DEM301 in Participants With Metastatic Colorectal Cancer | not yet recruiting | Phase 1 | 60 | DEM BioPharma, Inc.INDUSTRY | 0 | Sep 9, 2026 | clinicaltrials |
| NCT07808671 | A Decision Support Tool for Pancreatic Cancer Screening -Aim 2 | not yet recruiting | N/A | 40 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Sep 9, 2026 | clinicaltrials |
| NCT07809074 | Mindfulness and Self-Compassion Intervention for Ostomy Patients Due to Colorectal Cancer on Loneliness (MSC-OP)(MSC-OP) | not yet recruiting | N/A | 20 | The Hong Kong Polytechnic UniversityOTHER | 0 | Sep 9, 2026 | clinicaltrials |
| NCT07810114 | Total Neoadjuvant mFOLFOX6 Plus Suvemcitug and Enlonstobart With Selective Omission of Pelvic Radiotherapy for High-Risk Mid-Rectal Locally Advanced Rectal Cancer(SPARE) | not yet recruiting | Phase 2 | 52 | Fudan UniversityOTHER | 1 | Sep 9, 2026 | clinicaltrials |
| NCT07811076 | Serine/Glycine-Restricted Diet With Chemoradiotherapy for Rectal Cancer(SG-RCT) | not yet recruiting | Phase 1 / Phase 2 | 140 | Xuelei Ma MDOTHER | 1 | Sep 9, 2026 | clinicaltrials |
| NCT07811128 | Leveraging Digital Health Solutions to Collect Patient-Reported Outcomes in Rectal Cancer | not yet recruiting | — | 150 | University of California, San FranciscoOTHER | 1 | Sep 9, 2026 | clinicaltrials |
| NCT07779694 | 16-Hour Fasting Plus Serplulimab and CAPEOX as Neoadjuvant Therapy in pMMR/MSS Advanced Mid-to-Low Rectal Cancer | not yet recruiting | Phase 2 | 51 | Zhejiang UniversityOTHER | 0 | Sep 8, 2026 | clinicaltrials |
| NCT07795801 | Mind-Body Sexual Well-Being Program for Female GI Cancer Survivors | not yet recruiting | N/A | 100 | Massachusetts General HospitalOTHER | 1 | Sep 8, 2026 | clinicaltrials |
| NCT07806058 | An Open-Label, Multicenter, Phase IB/II Clinical Study of HRS-7172 in Combination With Antitumor Therapy in Participants With Solid Tumors | not yet recruiting | Phase 1 / Phase 2 | 140 | Jiangsu HengRui Medicine Co., Ltd.INDUSTRY | 1 | Sep 8, 2026 | clinicaltrials |
| NCT07806500 | Phase Ib Study of Oral R01 Monotherapy in Advanced Solid Tumors | not yet recruiting | Phase 1 | 18 | Beijing Anjianxi Bio-Medical Technology Co., Ltd.INDUSTRY | 1 | Sep 8, 2026 | clinicaltrials |
| NCT07807345 | Phase 1 Study of STRO-006 in Adults With Refractory Solid Tumors That Are Recurrent or Metastatic | not yet recruiting | Phase 1 | 285 | Sutro Biopharma, Inc.INDUSTRY | 1 | Sep 8, 2026 | clinicaltrials |
| NCT07807800 | A Study of DES-1357 in People With Deficient Mismatch Repair (dMMR)/Microsatellite Instability-High (MSI-H) Metastatic Colorectal Cancer (mCRC) | not yet recruiting | Phase 1 / Phase 2 | 88 | D. E. Shaw Research, LLCINDUSTRY | 0 | Sep 8, 2026 | clinicaltrials |
| NCT07807956 | A Study to Assess Adverse Events, Change in Disease Activity and How Intravenous ABBV-253 Moves Through the Body in Adult Participants With Advanced Solid Tumors | not yet recruiting | Phase 1 | 130 | AbbVieINDUSTRY | 0 | Sep 8, 2026 | clinicaltrials |
| NCT07808151 | Neoadjuvant Pembrolizumab and Porustobart in Resectable pMMR/MSS Colon Cancer | not yet recruiting | Phase 2 | 100 | Solstice Oncology, Inc.INDUSTRY | 6 | Sep 8, 2026 | clinicaltrials |
| NCT07803770 | EUS-Based Artificial Intelligence to Predict Outcomes in Pancreatic Cancer(EUS-AI-R) | not yet recruiting | — | 700 | IRCCS San RaffaeleOTHER | 1 | Sep 4, 2026 | clinicaltrials |
| NCT07803783 | A Study to Compare the Efficacy and Safety of YL201 With Standard Chemotherapy in Patients With Metastatic Pancreatic Cancer After Failure of Gemcitabine-Based Systemic Chemotherapy | not yet recruiting | Phase 3 | 320 | MediLink Therapeutics (Suzhou) Co., Ltd.INDUSTRY | 1 | Sep 4, 2026 | clinicaltrials |
| NCT07805681 | Observational Registry Evaluating the Clinical Impact of the Blood-Based Biomarker Test for Early-Stage Pancreatic Ductal Adenocarcinoma(ASSURE) | not yet recruiting | — | 400 | Immunovia, Inc.INDUSTRY | 0 | Sep 4, 2026 | clinicaltrials |
| NCT07418164 | Endoscopic Management of Biliopancreatic Disease in the Lombardy Pancreas Units(GENTLENESS) | not yet recruiting | — | 2,500 | IRCCS San RaffaeleOTHER | 1 | Sep 3, 2026 | clinicaltrials |
| NCT07801027 | A Trial of Pembrolizumab With Chemotherapy or Chemoradiotherapy in Participants From India With Different Types of Cancer (MK-3475-G44/KEYNOTE-G44) | not yet recruiting | Phase 4 | 150 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Sep 3, 2026 | clinicaltrials |
| NCT07802184 | GnP Combined With SHR-1701 and Apatinib as First-Line Treatment for Locally Advanced or Metastatic PDAC | not yet recruiting | Phase 1 / Phase 2 | 45 | West China HospitalOTHER | 1 | Sep 3, 2026 | clinicaltrials |
| NCT07802418 | Molecularly Tailored Therapy in Advanced Pancreatic Cancer(TAILOR-PANC) | not yet recruiting | Phase 2 | 1,200 | Herlev HospitalOTHER | 1 | Sep 3, 2026 | clinicaltrials |
| NCT07802847 | Innovative and Cooperative Pathway Integrating Oncogeriatric, Pharmaceutical and Pharmacological Follow-up in Elderly Patients.(POG) | not yet recruiting | Phase 4 | 794 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 1 | Sep 3, 2026 | clinicaltrials |
| NCT07803159 | Frailty, Immunonutrition, Surgery Type, and Biologic Recovery in Elderly Gastric Cancer | not yet recruiting | — | 328 | Kocaeli City HospitalOTHER_GOV | 1 | Sep 3, 2026 | clinicaltrials |
| NCT07363408 | Ivonescimab and ADG126, Alone, and in Combination With Leucovorin and Fluorouracil or FOLFIRI Regimen for the Treatment of Microsatellite Stable Advanced/Metastatic Colorectal Cancer | not yet recruiting | Phase 1 | 30 | City of Hope Medical CenterOTHER | 1 | Sep 2, 2026 | clinicaltrials |
| NCT07786792 | Biomarker and Mechanism Study of Systemic Therapy in Unresectable HCC(MUSE2) | not yet recruiting | — | 400 | Shanghai Zhongshan HospitalOTHER | 0 | Sep 2, 2026 | clinicaltrials |
| NCT07791758 | A Clinical Trial of LBL-024 Combination Drug in Patients With Metastatic Colorectal Carcinoma | not yet recruiting | Phase 1 / Phase 2 | 369 | Nanjing Leads Biolabs Co.,LtdINDUSTRY | 1 | Sep 2, 2026 | clinicaltrials |
| NCT07799077 | Paclitaxel Polymeric Micelles and Cisplatin Plus Sintilimab as Neoadjuvant Therapy for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma | not yet recruiting | Phase 2 | 32 | Hebei Medical University Fourth HospitalOTHER | 1 | Sep 2, 2026 | clinicaltrials |
| NCT07799298 | Spleen Preservation Versus Splenectomy in Left Pancreatectomy for Pancreatic Ductal Adenocarcinoma (SPLENDID)(SPLENDID RCT) | not yet recruiting | N/A | 360 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Sep 2, 2026 | clinicaltrials |
| NCT07799649 | ctDNA-MRD Monitoring After Neoadjuvant Therapy in Gastric Cancer With pCR or MPR | not yet recruiting | — | 150 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Sep 2, 2026 | clinicaltrials |
| NCT07800754 | A Study in Greece Observing How Patients With Stomach and Esophageal Cancer Are Diagnosed and Treated in Everyday Medical Practice(GRACE) | not yet recruiting | — | 300 | AstraZenecaINDUSTRY | 0 | Sep 2, 2026 | clinicaltrials |
| NCT07515729 | Raising Awareness of Colorectal Screening in American Indian Communities(AIC-DC) | not yet recruiting | — | 446 | University of OklahomaOTHER | 0 | Sep 1, 2026 | clinicaltrials |
Data updated 15 days agoSource updated Sep 15, 2026source: clinicaltrials