Cancer Family
Malignant Digestive System Neoplasm
CI-CAN-00000229Explore in graph →
4,262 active trials43 approved drugs556 evidence items
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Cancer Family
CI-CAN-00000229Explore in graph →
Clinical trials
19,108 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (2,001)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07510932 | Fruquintinib In Patients With Metastatic Colorectal Cancer Refractory to Standard Chemotherapies in South Korea Patients (FIRST-K)(FIRST-K) | not yet recruiting | Phase 2 | 88 | Korea University Anam HospitalOTHER | 0 | Apr 6, 2026 | clinicaltrials |
| NCT07511504 | Y-90 Radioembolization, Durvalumab, Tremelimumab, and Zanzalintinib for the Treatment of Unresectable and Locally-Advanced Hepatocellular Carcinoma | not yet recruiting | Phase 2 | 40 | OHSU Knight Cancer InstituteOTHER |
| 1 |
| Apr 6, 2026 |
| clinicaltrials |
| NCT07509398 | FMT Combined With Standard First-Line Therapy in Initially Unresectable Colorectal Cancer | not yet recruiting | Phase 2 / Phase 3 | 220 | Shanghai 10th People's HospitalOTHER | 0 | Apr 3, 2026 | clinicaltrials |
| NCT07509424 | Neoadjuvant Short-course Radiotherapy Followed by a Combination of Disitamab Vedotin, Sintilimab, and Capecitabine in Locally Advanced HER2-expressing Rectal Cance | not yet recruiting | Phase 2 | 29 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 0 | Apr 3, 2026 | clinicaltrials |
| NCT07507071 | Comparison of the Sensitivity of pCLE and Pathological Biopsy for Gastric Mucosal Lesions(pCLE) | not yet recruiting | — | 169 | Changhai HospitalOTHER | 1 | Apr 2, 2026 | clinicaltrials |
| NCT07507526 | A Study of Disitamab Vedotin, Tunlametinib, and PD-1 Antibody for Advanced Gastric Cancer(DTP-HER2) | not yet recruiting | Phase 2 | 76 | Sun Yat-sen UniversityOTHER | 1 | Apr 2, 2026 | clinicaltrials |
| NCT07507916 | Dynamic ctDNA-Guided Adjuvant Therapy in cStage III and IVA Gastric or Gastroesophageal Junction Adenocarcinoma | not yet recruiting | Phase 2 | 32 | Fudan UniversityOTHER | 0 | Apr 2, 2026 | clinicaltrials |
| NCT07505186 | Camrelizumab, Chemotherapy and Ivarmacitinib in Patients With Resectable Esophageal Squamous Cell Carcinoma | not yet recruiting | Phase 2 | 45 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Apr 1, 2026 | clinicaltrials |
| NCT07502963 | Effectiveness of a Multimodal Outpatient Supervised Physical Activity Program to Improve Tolerance and Efficacy of Chemotherapy in Adults With Breast, Lung and Colon Cancer(PREDU) | not yet recruiting | N/A | 70 | University of Vic - Central University of CataloniaOTHER | 1 | Mar 31, 2026 | clinicaltrials |
| NCT07503639 | Umbrella Trial of Neoadjuvant Therapy for Locally Advanced Colorectal Cancer | not yet recruiting | Phase 2 | 134 | Fudan UniversityOTHER | 0 | Mar 31, 2026 | clinicaltrials |
| NCT07504263 | Phase 1/2a Study of RP-001 in Participants With Advanced Malignancies | not yet recruiting | Phase 1 / Phase 2 | 66 | Recurv Pharma IncINDUSTRY | 0 | Mar 31, 2026 | clinicaltrials |
| NCT07502014 | A Clinical Study of Iparomlimab and Tuvonralimab Combined With Fruquintinib and Heterogeneous Radiotherapy Versus Fruquintinib as Third-Line and Subsequent-Line Treatment for Metastatic Colorectal Cancer | not yet recruiting | Phase 2 | 60 | Huazhong University of Science and TechnologyOTHER | 0 | Mar 30, 2026 | clinicaltrials |
| NCT07502027 | A Clinical Study of Iparomlimab and Tuvonralimab Combined With SOX Following Heterogeneous Radiotherapy as First-line Treatment for Unresectable Locally Advanced or Metastatic HER2-negative Gastric or Gastroesophageal Junction Adenocarcinoma | not yet recruiting | Phase 4 | 55 | Huazhong University of Science and TechnologyOTHER | 0 | Mar 30, 2026 | clinicaltrials |
| NCT07489833 | Metabolomic Pathways and Traditional Chinese Medicine Body Constitution in Cancer-related Fatigue | not yet recruiting | — | 80 | Chang Gung Memorial HospitalOTHER | 0 | Mar 27, 2026 | clinicaltrials |
| NCT07489768 | GNB4 and Riplet Gene Methylation Combined Detection Kit for Hepatocellular Carcinoma Recurrence Monitoring(CCGLC-019) | not yet recruiting | — | 162 | Tongji HospitalOTHER | 0 | Mar 24, 2026 | clinicaltrials |
| NCT07312370 | Esomeprazole Plus Sucralfate for Post-ESD Ulcer Healing | not yet recruiting | Phase 4 | 120 | LanZhou UniversityOTHER | 1 | Mar 23, 2026 | clinicaltrials |
| NCT07486310 | Evaluation of Pressurized Intraperitoneal Aerosol Chemotherapy With VRT106 Versus PIPAC in Patients With Advanced Gastric Cancer and PeritonealMetastasis: A Prospective, Multicenter, Open-Label, Randomized Controlled Trial | not yet recruiting | Phase 2 | 30 | Guangdong Provincial People's HospitalOTHER | 1 | Mar 20, 2026 | clinicaltrials |
| NCT07482774 | Tumor Microenvironment Changes After Neoadjuvant Chemo-Immunotherapy in Esophageal Squamous Cell Carcinoma(TME-ESCC) | not yet recruiting | — | 12 | Nanjing Medical UniversityOTHER | 0 | Mar 19, 2026 | clinicaltrials |
| NCT07483060 | Next Generation STAR-TREC (NG-ST) - Organ Preservation in Early Rectal Cancer(NG-ST) | not yet recruiting | Phase 4 | 90 | Vastra Gotaland RegionOTHER_GOV | 0 | Mar 19, 2026 | clinicaltrials |
| NCT06735638 | Outside the Cage (OTC) Robotic Esophagectomy | not yet recruiting | Phase 1 | 31 | Centre hospitalier de l'Université de Montréal (CHUM)OTHER | 1 | Mar 18, 2026 | clinicaltrials |
| NCT07470268 | Impact of Hypertrophy-oriented Resistance Training on Muscle Mass and Quality of Life in Patients With Unresectable Pancreatic Cancer(HY-PANC) | not yet recruiting | N/A | 10 | Universidad Europea de MadridOTHER | 1 | Mar 18, 2026 | clinicaltrials |
| NCT07481032 | Effect of Fufang Biejiaruangan Combined With Antiviral Therapy on the Incidence of Hepatocellular Carcinoma in Patients With Hepatitis B-related Cirrhosis: A Multicenter, Randomized, Placebo-controlled Study | not yet recruiting | N/A | 1,034 | Nanfang Hospital, Southern Medical UniversityOTHER | 0 | Mar 18, 2026 | clinicaltrials |
| NCT07477418 | PDAC Regression and Intraoperative Surgical Margin With Neoadjuvant TAMP (PRISM-TAMP)(PRISM-TAMP) | not yet recruiting | Phase 1 / Phase 2 | 10 | University of VermontOTHER | 1 | Mar 17, 2026 | clinicaltrials |
| NCT07472868 | Neoadjuvant FOLFOXIRI and Chemoradiotherapy Versus Neoadjuvant CAPOX/FOLFOX and Chemoradiotherapy Followed by Surgery or a Watch-and-Wait Approach in High Risk Locally Advanced Rectal Cancer(MEND-IT II) | not yet recruiting | Phase 3 | 394 | J. W. A. BurgerOTHER | 1 | Mar 16, 2026 | clinicaltrials |
| NCT07474025 | Integrating Peritoneal Histological Growth Patterns Into Preoperative Decision-Making for Colorectal Peritoneal Metastses | not yet recruiting | — | 30 | Jules Bordet InstituteOTHER | 1 | Mar 16, 2026 | clinicaltrials |
| NCT07469241 | Study of MRI Guided Personal Chemoradiotherapy and Immunotherapy for Limited Advanced Esophageal Squamous Caicinoma.(FUTURE-3) | not yet recruiting | Phase 2 | 50 | Fudan UniversityOTHER | 0 | Mar 13, 2026 | clinicaltrials |
| NCT07469306 | Short-Course RT Plus CAPOX and Tislelizumab vs Long-Course CRT Plus Tislelizumab for Locally Advanced Rectal Cancer | not yet recruiting | Phase 2 | 130 | Fujian Cancer HospitalOTHER_GOV | 1 | Mar 13, 2026 | clinicaltrials |
| NCT07467174 | RCT Comparing Reduced-port Robotic and Conventional Laparoscopic Subtotal Gastrectomy(REPROG-RCT) | not yet recruiting | Phase 4 | 538 | Yonsei UniversityOTHER | 1 | Mar 12, 2026 | clinicaltrials |
| NCT07467590 | Combination of High and Low-Dose Radiotherapy With Immune Therapy and TKI in Advanced Colorectal Cancer: A Phase II Study(TRIUNITE-07) | not yet recruiting | Phase 2 | 33 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 0 | Mar 12, 2026 | clinicaltrials |
| NCT07463690 | Construction and Evaluation of a Flipped Discharge Model for Stomates With Colorectal Cancer | not yet recruiting | N/A | 200 | Sun Yat-sen UniversityOTHER | 1 | Mar 11, 2026 | clinicaltrials |
| NCT07461675 | Effects of Neoadjuvant Immunotherapy on Anti-tumour Immunity in Hepatocellular Carcinoma Patients Undergoing Liver Resection | not yet recruiting | Phase 3 | 30 | University of Geneva, SwitzerlandOTHER | 1 | Mar 10, 2026 | clinicaltrials |
| NCT07453394 | QLS5132 Combination Therapy in Advanced Solid Tumors | not yet recruiting | Phase 1 / Phase 2 | 626 | Qilu Pharmaceutical Co., Ltd.INDUSTRY | 0 | Mar 6, 2026 | clinicaltrials |
| NCT07453797 | A Prospective Study Assessing ActivSight Imaging for Intraoperative Perfusion Evaluation in Left-Sided Colectomy(VISION) | not yet recruiting | N/A | 150 | Activ SurgicalINDUSTRY | 0 | Mar 6, 2026 | clinicaltrials |
| NCT07454486 | TRACE-BTC. Relation of Biomarkers and Patients Reported Quality of Life to Outcomes in Patients With Biliary Tract Cancer: a Real- World Cohort(TRACE-BTC) | not yet recruiting | — | 300 | Aarhus University HospitalOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT07455422 | A Study of Barrett's Esophagus Patients: Optimization of a Risk Model to Better Predict the Development of Cancer Recurrence and the Effect of Risk Profile Disclosure on Patient Quality of Life and Fear of Cancer(Endeavor-2) | not yet recruiting | N/A | 266 | University Hospital, AntwerpOTHER | 7 | Mar 6, 2026 | clinicaltrials |
| NCT07452471 | Comparison of the Postoperative Analgesic Effects of the Temperature-responsive Gel Mixed With Local Anesthetics Application and Ultrasound-guided Transversus Abdominis Plane Block in Patients Undergoing Laparoscopic Gastrectomy(TAP-WELPASS) | not yet recruiting | N/A | 80 | Gyeong-Jo Byeon, MD, PhDOTHER | 1 | Mar 5, 2026 | clinicaltrials |
| NCT07453173 | ONCO-RET: Supervised Resistance Training During Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer(ONCO-RET) | not yet recruiting | N/A | 15 | Fundacion Arturo Lopez PerezOTHER | 1 | Mar 5, 2026 | clinicaltrials |
| NCT07446543 | Effect of Negative-Pressure Drainage Versus Pancreatic Duct Stenting for Preventing Pancreatitis After Endoscopic Papillectomy for Duodenal Papillary Tumors | not yet recruiting | N/A | 132 | Cui XiaobingOTHER | 0 | Mar 4, 2026 | clinicaltrials |
| NCT07448376 | EUS-guided CTCs + Multi-omics: Predicting Pancreatic Cancer Recurrence and Metastases | not yet recruiting | — | 20 | Huazhong University of Science and TechnologyOTHER | 1 | Mar 4, 2026 | clinicaltrials |
| NCT07449637 | Real-World Treatment Patterns and Survival Outcomes in Patients With Intermediate-Stage Hepatocellular Carcinoma. | not yet recruiting | — | 200 | Sohag UniversityOTHER | 1 | Mar 4, 2026 | clinicaltrials |
| NCT07444840 | How Does Pre-operative Biliary Drainage in Pancreatic Adenocarcinoma Affect Surgical Outcomes in Pancreatic Cancer Surgery(PBDSOO) | not yet recruiting | — | 90 | East Lancashire Hospitals NHS TrustOTHER | 0 | Mar 3, 2026 | clinicaltrials |
| NCT07446335 | A Phase III Study of First-line Anlotinib Combined With Benmelstobart in Patients With Advanced Esophageal Squamous Cell Carcinoma | not yet recruiting | Phase 3 | 578 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Mar 3, 2026 | clinicaltrials |
| NCT07446465 | FOLFOX Chemotherapy Combined With Fruquintinib and Serplulimab as First-Line Conversion Therapy for Initially Unresectable pMMR/MSS Colorectal Cancer | not yet recruiting | Phase 4 | 42 | Ye XuOTHER | 1 | Mar 3, 2026 | clinicaltrials |
| NCT07435584 | Everolimus in CDK12-Deficient Metastatic Colorectal Cancer (EVER-RECODE)(EVER-RECODE) | not yet recruiting | Phase 1 / Phase 2 | 38 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 0 | Feb 27, 2026 | clinicaltrials |
| NCT07437287 | Testing Mitazalimab in Combination With Standard Chemotherapy in Immunotherapy Resistant Advanced Biliary Tract Cancers(CROCOBIL) | not yet recruiting | Phase 2 / Phase 3 | 160 | UNICANCEROTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT07437326 | Food-related Quality of Life in Patients With Cancer(QVA-Mod) | not yet recruiting | — | 180 | Hospices Civils de LyonOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT07438418 | An Observational Study on Gastric Cancer in High-risk Individuals | not yet recruiting | — | 3,000 | Fudan UniversityOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT06943794 | Eradication of Helicobacter Pylori Subtypes at High Gastric Cancer Risk: a Cluster-randomized Controlled Trial | not yet recruiting | N/A | 4,824 | Fudan UniversityOTHER | 1 | Feb 25, 2026 | clinicaltrials |
| NCT07432568 | A Study of Liposomal Irinotecan Plus 5-FU/LV HAIC With Lenvatinib and a PD-1 Inhibitor in Advanced ICC | not yet recruiting | Phase 2 | 30 | Tianjin Medical University Cancer Institute and HospitalOTHER | 0 | Feb 25, 2026 | clinicaltrials |
| NCT07429643 | Endoscopic Ultrasound-Guided Loco-regional Chemotherapy Injection as Adjuvant Therapy for Locally Advanced Pancreatic Cancer. | not yet recruiting | Phase 2 / Phase 3 | 20 | Assiut UniversityOTHER | 0 | Feb 24, 2026 | clinicaltrials |
Data updated 23 days agoSource updated Apr 6, 2026source: clinicaltrials