Subtype
Malignant Colorectal Neoplasm
CI-CAN-00005874Explore in graph →
1,565 active trials21 approved drugs382 evidence items
- NCIt
- C4978
- DOID
- 9256
- Other
- 1 more code
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Subtype
CI-CAN-00005874Explore in graph →
Clinical trials
7,296 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (722)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07254910 | Feasibility of a Multi-Channel Intervention to Promote Colorectal Cancer Screening Among American Indians in Oklahoma(YVONNE) | recruiting | N/A | 150 | University of OklahomaOTHER | 1 | Jul 30, 2026 | clinicaltrials |
| NCT07733817 | Impact of Probiotics on Neuropathy Induced by Adjuvant Chemotherapy in Patients With Colon Cancer.(PROBIOCOL) | not yet recruiting | N/A | 130 | Centre Francois BaclesseOTHER | 1 | Jul 30, 2026 |
| clinicaltrials |
| NCT07736495 | Protective Role of Alpha-Lipoic Acid in Chemotherapy-Induced Mucositis | recruiting | Phase 2 / Phase 3 | 50 | Ain Shams UniversityOTHER | 1 | Jul 30, 2026 | clinicaltrials |
| NCT07738042 | To Explore a Single-arm Phase II Study on Intestinal Microbiota Transplantation Combined With Neoadjuvant Immunotherapy and Chemoradiotherapy for Locally Advanced Rectal Cancer Under MSS/pMMR | not yet recruiting | N/A | 46 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Jul 30, 2026 | clinicaltrials |
| NCT03526835 | A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors | recruiting | Phase 1 / Phase 2 | 560 | Merus B.V.INDUSTRY | 7 | Jul 29, 2026 | clinicaltrials |
| NCT05024097 | A Phase I-II Study to Test the Safety and Efficacy of PD1 (AB122) and Adenosine Receptor (AB928) Antagonists With Chemotherapy After Short-Course Radiation for Rectal Cancer.(PANTHER) | recruiting | Phase 2 | 43 | Weill Medical College of Cornell UniversityOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT06562192 | Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers | recruiting | Phase 1 | 162 | Novartis PharmaceuticalsINDUSTRY | 10 | Jul 29, 2026 | clinicaltrials |
| NCT06802172 | Effect of Meal Timing During Cancer Treatment in Patients in Alaska: A Randomized Clinical Trial | recruiting | N/A | 100 | Fred Hutchinson Cancer CenterOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT07409805 | YMN-136 Vaccine for Patients With Liver Metastasis of Colorectal Cancer Progressing After Third-Line Treatment | recruiting | Phase 1 | 9 | West China HospitalOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT07732686 | Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry | not yet recruiting | — | 2,000 | University of OklahomaOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT07732894 | Aerobic Exercise and Guided Imagery in Low Anterior Resection Syndrome | recruiting | N/A | 50 | Biruni UniversityOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT04098471 | Total Meso-rectal Excision Versus Transanal Local Excision Followed by Radiotherapy for T2N0M0 Distal Rectal Cancer | recruiting | N/A | 168 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Jul 28, 2026 | clinicaltrials |
| NCT05009069 | A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant Chemoradiotherapy in Participants With Locally Advanced Rectal Cancer | active not recruiting | Phase 2 | 58 | Hoffmann-La RocheINDUSTRY | 1 | Jul 28, 2026 | clinicaltrials |
| NCT06321081 | ICE Study: Combination of Irinotecan Plus Cetuximab and Envafolimab as a Rechallenge Regimen in mCRC | recruiting | Phase 2 | 60 | Beijing HospitalOTHER_GOV | 1 | Jul 28, 2026 | clinicaltrials |
| NCT06685497 | COLORECTUM+ Digital System for Postoperative Quality Improvement in Colorectal Cancer | recruiting | N/A | 236 | RenJi HospitalOTHER | 1 | Jul 28, 2026 | clinicaltrials |
| NCT07411599 | Dual Administration Of Intraperitoneal And Intravenous TROP2-Directed CAR-NK With TGF-Beta Receptor 2 (TGFBR2) Knock Out (KO) Therapy For Colorectal Cancer-Related Peritoneal Carcinomatosis: A Phase 1/2 Trial ("Chip-CRC Trial") | recruiting | Phase 1 / Phase 2 | 28 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 28, 2026 | clinicaltrials |
| NCT07580339 | Combining DCSZ11 With Radiation and Chemotherapy as Neoadjuvant Treatment for pMMR Locally Advanced Rectal Cancer | not yet recruiting | Phase 2 | 30 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Jul 28, 2026 | clinicaltrials |
| NCT04117087 | Pooled Mutant KRAS-Targeted Long Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Resected Mismatch Repair Protein (MMR-p) Colorectal and Pancreatic Cancer | active not recruiting | Phase 1 | 27 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Jul 27, 2026 | clinicaltrials |
| NCT06414122 | Modulated Mid-frequency Whole-body Electromyostimulation and Nutritional Therapy in Gastrointestinal Cancer Patients(MOMENT) | not yet recruiting | N/A | 88 | University of CologneOTHER | 1 | Jul 27, 2026 | clinicaltrials |
| NCT07436637 | Guardant Shield Colorectal Cancer Screening | recruiting | N/A | 500 | University of MiamiOTHER | 1 | Jul 27, 2026 | clinicaltrials |
| NCT07726966 | Betacyanin for Early Diagnosis and Recovery of Anastomotic Leakage After Rectal Cancer Surgery: A Single-Center, Prospective, Controlled Trial | not yet recruiting | N/A | 120 | Southwest Hospital, ChinaOTHER | 1 | Jul 27, 2026 | clinicaltrials |
| NCT07729605 | FOLFIRI Plus Bevacizuamb and QL1706 in Second-Line Treatment for mCRC(FIRBIT) | not yet recruiting | Phase 3 | 270 | Sun Yat-sen UniversityOTHER | 1 | Jul 27, 2026 | clinicaltrials |
| NCT01696981 | Screening for Colorectal Cancer in Older Patients (PLCO Screening Trial) | active not recruiting | N/A | 154,900 | National Cancer Institute (NCI)NIH | 1 | Jul 24, 2026 | clinicaltrials |
| NCT04258137 | Circulating DNA to Improve Outcome of Oncology PatiEnt. A Randomized Study(COPE) | active not recruiting | N/A | 332 | Institut BergoniéOTHER | 1 | Jul 24, 2026 | clinicaltrials |
| NCT04677413 | Ultra-fractionated Radiotherapy for Rectal Cancer | active not recruiting | Phase 1 | 27 | University of Texas Southwestern Medical CenterOTHER | 1 | Jul 24, 2026 | clinicaltrials |
| NCT04776655 | Study in mCRC Patients RAS/BRAF wt Tissue and RAS Mutated LIquid BIopsy to Compare FOLFIRI Plus CetuxiMAb or BevacizumaB(LIBImAb) | active not recruiting | Phase 3 | 280 | Azienda USL Reggio Emilia - IRCCSOTHER_GOV | 1 | Jul 24, 2026 | clinicaltrials |
| NCT05253846 | Short-course Radiotherapy Followed by Consolidation Chemotherapy. 2021-001206-29(ShorTrip) | active not recruiting | Phase 2 | 63 | Gruppo Oncologico del Nord-OvestOTHER | 1 | Jul 24, 2026 | clinicaltrials |
| NCT05394714 | A Phase I, Autologous ex Vivo Expanded and Activated NK Cell, Magicell-NK, Infusion for Colon Cancer Post Resection Study | recruiting | Phase 1 | 18 | Medigen Biotechnology CorporationINDUSTRY | 1 | Jul 24, 2026 | clinicaltrials |
| NCT07094893 | Anti-EGFR Agents in Patients With Right-sided Advanced Colorectal Cancer With Wild-type RAS and AREG/EREG High Status(ARIEL-ENGIC) | not yet recruiting | Phase 4 | 280 | Gruppo Oncologico del Nord-OvestOTHER | 0 | Jul 24, 2026 | clinicaltrials |
| NCT07104604 | Study on the Efficacy and Safety of Neoadjuvant Radiotherapy Combined With Tislelizumab, Liposomal Irinotecan, and Capecitabine in the Treatment of pMMR Locally Advanced Rectal Adenocarcinoma With Low Rectal Involvement | recruiting | Phase 2 | 51 | Affiliated Cancer Hospital of Shantou University Medical CollegeOTHER | 1 | Jul 24, 2026 | clinicaltrials |
| NCT07118800 | Study Evaluating Two Treatment Strategies for Rectal Cancer in Patients ≥75 Years Old(NACRE-2) | not yet recruiting | Phase 3 | 160 | UNICANCEROTHER | 0 | Jul 24, 2026 | clinicaltrials |
| NCT07724223 | Fruquintinib Plus Anti-EGFR Antibody for Third-Line Treatment of RAS Wild-Type mCRC | recruiting | Phase 2 | 46 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Jul 24, 2026 | clinicaltrials |
| NCT06974110 | Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors | recruiting | Phase 1 | 132 | MOMA TherapeuticsINDUSTRY | 2 | Jul 23, 2026 | clinicaltrials |
| NCT07042243 | The Florida ASCENT Study | recruiting | N/A | 100 | University of FloridaOTHER | 1 | Jul 23, 2026 | clinicaltrials |
| NCT07133750 | PM8002 (BNT327) in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancer | recruiting | Phase 2 | 100 | Biotheus Inc.INDUSTRY | 1 | Jul 23, 2026 | clinicaltrials |
| NCT07500298 | Phase 1 Study Of SAR445877 In Combination With FOLFOX6 And Bevacizumab As First-Line Treatment For Microsatellite Stable Metastatic Colorectal Cancer | recruiting | Phase 1 | 41 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 23, 2026 | clinicaltrials |
| NCT07589205 | Study of IBI3028 in Participants With Locally Advanced, Unresectable, or Metastatic Solid Tumors | recruiting | Phase 1 | 493 | Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD.INDUSTRY | 1 | Jul 23, 2026 | clinicaltrials |
| NCT07692555 | Development and Validation of a Colorectal Cancer Diagnostic Model | not yet recruiting | — | 20,000 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jul 23, 2026 | clinicaltrials |
| NCT02298959 | Testing the PD-1 Antibody, MK3475, Given With Ziv-aflibercept in Patients With Advanced Cancer | active not recruiting | Phase 1 | 59 | National Cancer Institute (NCI)NIH | 2 | Jul 22, 2026 | clinicaltrials |
| NCT03796884 | Linaclotide in Treating Patients With Stages 0-3 Colorectal Cancer | active not recruiting | Phase 2 | 150 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | Jul 22, 2026 | clinicaltrials |
| NCT03822572 | ABCSG C08-Exercise II: Trial of Endurance Exercise Following Adjuvant Chemotherapy for Colorectal Cancer(ABCSG C08) | active not recruiting | N/A | 92 | Austrian Breast & Colorectal Cancer Study GroupNETWORK | 1 | Jul 22, 2026 | clinicaltrials |
| NCT05848739 | A Phase 1-2 of ST316 With Selected Advanced Unresectable and Metastatic Solid Tumors | active not recruiting | Phase 1 | 130 | Sapience TherapeuticsINDUSTRY | 1 | Jul 22, 2026 | clinicaltrials |
| NCT06130826 | Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer | recruiting | Phase 1 | 24 | City of Hope Medical CenterOTHER | 1 | Jul 22, 2026 | clinicaltrials |
| NCT06834126 | Papaverine in Combination With Radiation Therapy for the Treatment of Locally Advanced Rectal Cancer, DINOMITE Trial | recruiting | Phase 1 | 36 | City of Hope Medical CenterOTHER | 1 | Jul 22, 2026 | clinicaltrials |
| NCT07318805 | A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors | recruiting | Phase 1 | 260 | PfizerINDUSTRY | 1 | Jul 22, 2026 | clinicaltrials |
| NCT07340567 | Personalizing Chemotherapy Selection After Surgery for Patients With Stage III Colorectal Cancer Using a Blood Test(CIRCULATEIII) | active not recruiting | Phase 3 | 2,450 | UNICANCEROTHER | 2 | Jul 22, 2026 | clinicaltrials |
| NCT07718490 | Immunotheray Combined With Simvastatin and Target Therapy and Chemotharepy for Advanced Colorectal Cancer | recruiting | Phase 2 | 43 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Jul 22, 2026 | clinicaltrials |
| NCT07720245 | Effectiveness of a Self-health Assessment Mobile Application in Young-to-midlife Adults in Hong Kong | recruiting | N/A | 574 | The University of Hong KongOTHER | 1 | Jul 22, 2026 | clinicaltrials |
| NCT07720505 | COLOFLOW: Laser Speckle Contrast Imaging Versus Near-infrared Fluorescence Imaging With Indocyanine Green(COLOFLOW) | not yet recruiting | — | 30 | Leiden University Medical CenterOTHER | 0 | Jul 22, 2026 | clinicaltrials |
| NCT04751435 | Developing New Educational Materials About Genetic Testing for a Diverse Group of Cancer Patients(IMAGINE) | recruiting | N/A | 445 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jul 21, 2026 | clinicaltrials |
Data updated 23 days agoSource updated Jul 30, 2026source: clinicaltrials