Subtype
Malignant Colorectal Neoplasm
CI-CAN-00005874Explore in graph →
1,565 active trials21 approved drugs382 evidence items
- NCIt
- C4978
- DOID
- 9256
- Other
- 1 more code
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Subtype
CI-CAN-00005874Explore in graph →
Clinical trials
7,296 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (722)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02851004 | Special Combination of BBI608 and Pembrolizumab | terminated | Phase 1 / Phase 2 | 55 | Takayuki YoshinoOTHER | 1 | Sep 5, 2021 | clinicaltrials |
| NCT02908451 | A Study of AbGn-107 in Patients With Gastric, Colorectal, Pancreatic or Biliary Cancer | terminated | Phase 1 | 39 | AbGenomics B.V Taiwan BranchINDUSTRY | 2 | Jul 13, 2021 | clinicaltrials |
| NCT01767857 |
| A Phase III Study of Xilonix in Patients With Advanced Colorectal Cancer(XCITE) |
| terminated |
| Phase 3 |
| 643 |
| Janssen Research & Development, LLCINDUSTRY |
| 13 |
| Jun 29, 2021 |
| clinicaltrials |
| NCT03856255 | Polyp Measurement Device | terminated | N/A | 36 | NYU Langone HealthOTHER | 1 | Jun 14, 2021 | clinicaltrials |
| NCT03311750 | Anti-EGFR Therapy Rechallenge in Combination With Chemotherapy in Patients With Advanced Colorectal Cancer(A-REPEAT) | terminated | Phase 2 | 23 | Hellenic Cooperative Oncology GroupOTHER | 2 | Jun 7, 2021 | clinicaltrials |
| NCT02448810 | Phase 2a Study of BAX69 and 5-FU/Leucovorin or Panitumumab Versus Standard of Care in Subjects With Metastatic Colorectal Cancer | terminated | Phase 2 | 115 | Baxalta now part of ShireINDUSTRY | 1 | May 25, 2021 | clinicaltrials |
| NCT03158610 | Biological-guided Metronomic Chemotherapy as Maintenance Strategy in Metastatic Colorectal Cancer | terminated | Phase 2 / Phase 3 | 20 | Ruijin HospitalOTHER | 1 | May 3, 2021 | clinicaltrials |
| NCT02117466 | Image Guided Treatment Optimization With Cetuximab for Patients With Metastatic Colorectal Cancer(IMPACT-CRC) | terminated | Phase 1 / Phase 2 | 85 | Amsterdam UMC, location VUmcOTHER | 1 | Apr 14, 2021 | clinicaltrials |
| NCT03137706 | Characterization of Mechanical Tissue Properties in Patients With Pancreatic, Liver, or Colon Cancer | terminated | — | 8 | University of Southern CaliforniaOTHER | 1 | Apr 5, 2021 | clinicaltrials |
| NCT01280643 | Combination Chemotherapy and Cetuximab or Bevacizumab in Treating Patients With Metastatic Colorectal Cancer | terminated | N/A | 3 | Fox Chase Cancer CenterOTHER | 1 | Mar 15, 2021 | clinicaltrials |
| NCT02550743 | BrUOG 302:BYL719, Capecitabine and Radiation for Rectal Cancer: A Brown University Oncology Research Group Study | terminated | Phase 1 | 7 | howard safranOTHER | 1 | Mar 12, 2021 | clinicaltrials |
| NCT00005944 | Second-look Surgery With or Without Intraperitoneal Chemotherapy in Treating Patients With Recurrent Colorectal Cancer | terminated | Phase 2 | — | UNICANCEROTHER | 2 | Feb 17, 2021 | clinicaltrials |
| NCT01318161 | Epidural Versus Patient-controlled Analgesia for Reduction in Long-term Mortality Following Colorectal Cancer Surgery(EPICOL) | terminated | Phase 3 | 221 | Örebro University, SwedenOTHER | 1 | Feb 16, 2021 | clinicaltrials |
| NCT02614157 | Lateral Lymph Node Dissection After Neoadjuvant Chemo-radiation in Advanced Low Rectal Cancer | terminated | N/A | 51 | West China HospitalOTHER | 1 | Feb 1, 2021 | clinicaltrials |
| NCT04664543 | Efficacy of Free Versus Low Residue Diet as Preparation for Screening Colonoscopy(CriLi) | terminated | N/A | 100 | Parc Taulí Hospital UniversitariOTHER | 1 | Jan 26, 2021 | clinicaltrials |
| NCT03149679 | The p53 Colorectal Cancer Trial | terminated | Phase 2 | 12 | Haukeland University HospitalOTHER | 1 | Jan 22, 2021 | clinicaltrials |
| NCT03170115 | Induction Chemotherapy Plus Chemoradiotherapy With or Without Aspirin in High Risk Rectal Cancer(ICAR) | terminated | Phase 2 | 25 | Instituto Nacional de Cancer, BrazilOTHER_GOV | 1 | Dec 17, 2020 | clinicaltrials |
| NCT00023868 | Combination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655) | terminated | Phase 3 | — | American College of Radiology Imaging NetworkNETWORK | 1 | Dec 2, 2020 | clinicaltrials |
| NCT00986440 | Study of CS-7017 in Colorectal Cancer Patients Who Have Achieved Disease Control Following First-Line Chemotherapy | terminated | Phase 2 | 84 | Daiichi SankyoINDUSTRY | 9 | Nov 5, 2020 | clinicaltrials |
| NCT02010567 | Neoadjuvant Chemoradiotherapy With CRLX-101 and Capecitabine for Rectal Cancer | terminated | Phase 1 / Phase 2 | 32 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Nov 3, 2020 | clinicaltrials |
| NCT02757391 | CD8+ T Cell Therapy and Pembrolizumab in Treating Patients With Metastatic Gastrointestinal Tumors | terminated | Phase 1 | 1 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 30, 2020 | clinicaltrials |
| NCT03724253 | [68Ga]-NeoBOMB1 Imaging in Patients With Malignancies Known to Overexpress Gastrin Releasing Peptide Receptor (GRPR)(NeoFIND) | terminated | Phase 2 | 19 | Advanced Accelerator ApplicationsINDUSTRY | 2 | Oct 23, 2020 | clinicaltrials |
| NCT00671645 | Preoperative Combined RadioChemo-Molecular Target Therapy With Capecitabine, Bevacizumab, and Radiotherapy | terminated | Phase 2 | 8 | Austrian Breast & Colorectal Cancer Study GroupNETWORK | 1 | Oct 19, 2020 | clinicaltrials |
| NCT02012231 | Phase I/IIa Study to Evaluate the Safety, PK, PD, and Preliminary Efficacy of PLX8394 in Patients With Advanced Cancers. | terminated | Phase 1 | 5 | Fore BiotherapeuticsINDUSTRY | 1 | Oct 19, 2020 | clinicaltrials |
| NCT03549338 | Sym004 Versus Futuximab or Modotuximab in Patients With mCRC | terminated | Phase 2 | 2 | Symphogen A/SINDUSTRY | 4 | Sep 28, 2020 | clinicaltrials |
| NCT03957096 | A Safety Study of SGN-CD47M in Patients With Solid Tumors | terminated | Phase 1 | 16 | Seagen Inc.INDUSTRY | 1 | Sep 17, 2020 | clinicaltrials |
| NCT03029988 | An Evaluation of Tilmanocept by IV Injection Using SPECT/CT vs PET Imaging in Subjects With Liver Metastases. | terminated | Phase 1 | 3 | Navidea BiopharmaceuticalsINDUSTRY | 1 | Sep 10, 2020 | clinicaltrials |
| NCT01367275 | Irinotecan Plus Brivanib in Metastatic Colorectal Cancer (CRC) Enriched for Elevated Levels of Plasma FGF | terminated | Phase 2 | 8 | M.D. Anderson Cancer CenterOTHER | 1 | Sep 3, 2020 | clinicaltrials |
| NCT02346955 | Study of CM-24 (MK-6018) Alone and In Combination With Pembrolizumab (MK-3475) in Participants With Selected Advanced or Recurrent Malignancies (MK-6018-001) | terminated | Phase 1 | 27 | Famewave Ltd.INDUSTRY | 2 | Aug 27, 2020 | clinicaltrials |
| NCT03035253 | A Study of OMP-305B83 in Subjects With Metastatic Colorectal Cancer | terminated | Phase 1 | 16 | OncoMed Pharmaceuticals, Inc.INDUSTRY | 1 | Aug 11, 2020 | clinicaltrials |
| NCT00740961 | Older Patients With Newly Diagnosed Breast Cancer or Colon Cancer | terminated | — | 63 | Case Comprehensive Cancer CenterOTHER | 1 | Jul 27, 2020 | clinicaltrials |
| NCT02453490 | Compare Efficacy and Safety of Raltitrexed-based and 5fu-based Neoadjuvant Chemotherapy for Colorectal Liver Metastasis | terminated | Phase 3 | 360 | Zhejiang UniversityOTHER | 1 | Jul 14, 2020 | clinicaltrials |
| NCT02652702 | Study Comparing Circular Stapler-assisted Colostomy vs Hand-stitching Colostomy of Colorectal Cancer Patients(STAPLER) | terminated | Phase 2 | 60 | Zhejiang UniversityOTHER | 1 | Jul 7, 2020 | clinicaltrials |
| NCT02205307 | A Study Assessing Perfusion Outcomes With PINPOINT® Near Infrared Fluorescence Imaging in Low Anterior Resection(PILLAR III) | terminated | N/A | 347 | Novadaq Technologies ULC, now a part of StrykerINDUSTRY | 1 | Jun 24, 2020 | clinicaltrials |
| NCT03300609 | 5-FU Based Maintenance Therapy in RAS Wild Type Metastatic Colorectal Cancer After Induction With FOLFOX Plus Panitumumab | terminated | Phase 3 | 4 | University of Southern CaliforniaOTHER | 1 | Jun 11, 2020 | clinicaltrials |
| NCT03480152 | Messenger RNA (mRNA)-Based, Personalized Cancer Vaccine Against Neoantigens Expressed by the Autologous Cancer | terminated | Phase 1 / Phase 2 | 5 | National Cancer Institute (NCI)NIH | 1 | Jun 2, 2020 | clinicaltrials |
| NCT03258541 | Organ-sparing With TraceIT® for Rectal Cancer Radiotherapy | terminated | N/A | 2 | Thomas ZilliOTHER | 1 | May 15, 2020 | clinicaltrials |
| NCT02052921 | Observation Versus Surgical Resection in Patients With Rectal Cancer Who Achieved Complete Clinical Response After Neoadjuvant Chemoradiotherapy | terminated | N/A | 13 | Instituto do Cancer do Estado de São PauloOTHER | 1 | May 11, 2020 | clinicaltrials |
| NCT00602329 | MRI in Predicting Response in Patients Receiving Combination Chemotherapy and Bevacizumab For Advanced or Metastatic Colorectal Cancer | terminated | Phase 2 | 5 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Apr 28, 2020 | clinicaltrials |
| NCT03705013 | Observational Study of Sub-populations From Cologuard Post-Approval Study (2014-01) | terminated | — | 51 | Exact Sciences CorporationINDUSTRY | 1 | Apr 14, 2020 | clinicaltrials |
| NCT03487484 | Quality of Life in Patients With Rectal Cancer Receiving Total Mesorectal Excision With or Without Stoma | terminated | — | 5 | University Hospital, Basel, SwitzerlandOTHER | 1 | Apr 10, 2020 | clinicaltrials |
| NCT00353457 | Capecitabine,Oxaliplatin & Erbitux Given Throughout Multi-Modal Therapy for Locally Advanced Rectal Adenocarcinoma | terminated | Phase 2 | 6 | Abramson Cancer Center at Penn MedicineOTHER | 0 | Apr 9, 2020 | clinicaltrials |
| NCT00091286 | Vaccine Therapy in Treating Patients With Stage IIB, Stage III, or Stage IV Colorectal Cancer | terminated | Early Phase 1 | 11 | Craig L Slingluff, JrOTHER | 1 | Mar 30, 2020 | clinicaltrials |
| NCT02889276 | Effects of Functional Exercise on Fitness and QoL in Cancer Survivors(RETRACE) | terminated | N/A | 4 | University of PortsmouthOTHER | 1 | Mar 26, 2020 | clinicaltrials |
| NCT00207831 | Trial Testing Ftorafur (UFT) Associated With Neoadjuvant Radiotherapy Versus Radiotherapy Alone in Rectal Adenocarcinoma(UFT RT Phase 3) | terminated | Phase 3 | 219 | Institut Cancerologie de l'OuestOTHER | 1 | Mar 25, 2020 | clinicaltrials |
| NCT01547923 | Pre-therapeutic Identification of Dihydropyrimidine Dehydrogenase Gene (DPD) Deficiency for Predicting Toxicity to Fluoropyrimidines(DPD côlon) | terminated | N/A | 1,142 | Institut Cancerologie de l'OuestOTHER | 1 | Mar 25, 2020 | clinicaltrials |
| NCT02141295 | A Study Comparing the Efficacy and Safety of Vanucizumab and FOLFOX With Bevacizumab and FOLFOX in Participants With Untreated Metastatic Colorectal Cancer(McCAVE) | terminated | Phase 2 | 197 | Hoffmann-La RocheINDUSTRY | 7 | Mar 25, 2020 | clinicaltrials |
| NCT02797405 | Tumour and HEalthy Tissues DOse-response and Radiosensitivity Assay(THEODORA) | terminated | N/A | 97 | Centre Leon BerardOTHER | 1 | Mar 25, 2020 | clinicaltrials |
| NCT01504477 | Panitumumab and Bortezomib for Patients With Advanced Colorectal Cancer | terminated | Phase 1 / Phase 2 | 6 | Georgetown UniversityOTHER | 1 | Mar 16, 2020 | clinicaltrials |
| NCT01557881 | Positron Emission Tomography/Magnetic Resonance Imaging in Patients | terminated | N/A | 98 | Case Comprehensive Cancer CenterOTHER | 1 | Feb 24, 2020 | clinicaltrials |
Data updated 23 days agoSource updated Sep 5, 2021source: clinicaltrials