Subtype
Malignant Colorectal Neoplasm
CI-CAN-00005874Explore in graph →
1,565 active trials21 approved drugs382 evidence items
- NCIt
- C4978
- DOID
- 9256
- Other
- 1 more code
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Subtype
CI-CAN-00005874Explore in graph →
Clinical trials
7,296 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (722)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02510378 | Short Course Radiotherapy Combined With Chemotherapy in Stage IV Rectal Cancer With Resectable Liver Metastases | unknown | Phase 2 | 47 | Chinese Academy of Medical SciencesOTHER | 1 | Jul 29, 2015 | clinicaltrials |
| NCT00100841 | Phase II Trial of FOLFOX6, Bevacizumab and Cetuximab in Patients With Colorectal Cancer | completed | Phase 2 | 66 | National Cancer Institute (NCI)NIH | 1 | Jul 27, 2015 | clinicaltrials |
| NCT01161316 | Safety and Efficacy Study of mFOLFOX-6 Plus Cetuximab for 8 Cycles Followed by mFOLFOX-6 Plus Cetuximab or Single Agent Cetuximab as Maintenance Therapy in Patients With Metastatic Colorectal Cancer and WT KRAS Tumours(MACRO-2) | completed | Phase 2 | 194 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)OTHER | 1 | Jul 27, 2015 | clinicaltrials |
| NCT00052507 | Bortezomib in Treating Patients With Metastatic or Recurrent Colorectal Cancer | completed | Phase 2 | — | University Health Network, TorontoOTHER | 1 | Jul 23, 2015 | clinicaltrials |
| NCT01853813 | First-line Irinotecan, Lederfolin and 5FU (FOLFIRI) and Bevacizumab in Patients With Advanced Colorectal Cancer(CENTRAL) | completed | Phase 2 | 85 | Gruppo Italiano per lo studio dei Carcinomi dell'Apparato DigerenteOTHER | 1 | Jul 15, 2015 | clinicaltrials |
| NCT01300858 | A Study of the Safety and Biological Activity of Intraperitoneal (IP) EGEN-001 Administered Alone and in Combination With Standard Chemotherapy in Colorectal Peritoneal Carcinomatosis Patients | terminated | Phase 1 / Phase 2 | 4 | EGEN, Inc.INDUSTRY | 1 | Jul 13, 2015 | clinicaltrials |
| NCT00890305 | Study to Evaluate the Safety, Tolerability and Efficacy of FOLFOX + CT-011 Versus FOLFOX Alone | completed | Phase 2 | 171 | Medivation, Inc.INDUSTRY | 6 | Jul 8, 2015 | clinicaltrials |
| NCT01478594 | A Study Combining mFOLFOX6 With Tivozanib or Bevacizumab in Patients With Metastatic Colorectal Cancer as First Line Therapy | completed | Phase 2 | 265 | AVEO Pharmaceuticals, Inc.INDUSTRY | 12 | Jul 8, 2015 | clinicaltrials |
| NCT02490709 | Local Excision of Clinical T3 Rectal Adenocarcinoma Showing Major Response(ycT0-1) After Neoadjuvant Chemoradiotherapy | unknown | Phase 2 | 86 | National Cancer Center, KoreaOTHER_GOV | 1 | Jul 7, 2015 | clinicaltrials |
| NCT02488707 | Minimally Invasive Sphincter Sparing Total Mesorectal Excision for Ultra-low Rectal Cancer After Initial Chemo-radiotherapy (MISS-TRICR).(MISS-TRICR) | unknown | Phase 2 | 250 | Mansoura UniversityOTHER | 1 | Jul 2, 2015 | clinicaltrials |
| NCT01461148 | Vaccination Against MSI Colorectal Cancer | completed | Phase 1 / Phase 2 | 22 | Oryx GmbH & Co. KGINDUSTRY | 1 | Jun 23, 2015 | clinicaltrials |
| NCT00004195 | Eniluracil and Surgery in Treating Patients With Primary or Metastatic Colorectal Cancer | completed | Phase 2 | 28 | University of Alabama at BirminghamOTHER | 0 | Jun 15, 2015 | clinicaltrials |
| NCT01818973 | Preoporative Bevacizumab, Radiation Therapy, and XELOX Chemotherapy for Locally Advanced Nonmetastatic Rectal Cancer | unknown | Phase 2 | 45 | Sun Yat-sen UniversityOTHER | 1 | Jun 8, 2015 | clinicaltrials |
| NCT01131078 | A Study of Avastin (Bevacizumab) in Combination Chemotherapy in Patients With Metastatic Cancer of the Colon or Rectum | completed | Phase 2 | 306 | Hoffmann-La RocheINDUSTRY | 1 | Jun 4, 2015 | clinicaltrials |
| NCT01375816 | Liposome-encapsulated Irinotecan Hydrochloride PEP02 or Irinotecan Hydrochloride, Leucovorin Calcium, and Fluorouracil as Second-Line Therapy in Treating Patients With Metastatic Colorectal Cancer(PEPCOL) | terminated | Phase 2 | 55 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Jun 4, 2015 | clinicaltrials |
| NCT01226719 | FOLFOXIRI Plus Panitumumab Patients With Metastatic KRAS Wild-Type Colorectal Cancer With Liver Metastases Only | completed | Phase 2 | 15 | SCRI Development Innovations, LLCOTHER | 1 | May 27, 2015 | clinicaltrials |
| NCT00735241 | FOLFOX6 Plus Sir-Spheres Microspheres Plus Avastin in Patients With Nonresectable Liver Metastases From Colorectal Carcinoma(FAST) | withdrawn | Phase 2 / Phase 3 | 0 | Sirtex MedicalINDUSTRY | 1 | May 22, 2015 | clinicaltrials |
| NCT01211210 | Neoadjuvant FOLFOX6 Chemotherapy With or Without Radiation in Rectal Cancer(FOWARC) | unknown | Phase 2 / Phase 3 | 495 | Sun Yat-sen UniversityOTHER | 1 | May 22, 2015 | clinicaltrials |
| NCT01108107 | Neoadjuvant Treatment of Colon Cancer | completed | Phase 2 | 76 | Vejle HospitalOTHER | 1 | May 21, 2015 | clinicaltrials |
| NCT01110941 | Feasibility Study of SOL (S-1,Oral Leucovorin,and Oxaliplatin) for Colorectal Cancer in China(SCI-101) | completed | Phase 1 / Phase 2 | 20 | Shen LinOTHER | 1 | May 19, 2015 | clinicaltrials |
| NCT00522665 | Phase I/Randomized Phase II Study of Second Line Therapy With Irinotecan + Cetuximab +/- RAD001 for Colorectal Cancer | completed | Phase 1 / Phase 2 | 41 | Hoosier Cancer Research NetworkOTHER | 1 | May 15, 2015 | clinicaltrials |
| NCT00778830 | Study Evaluating the Safety and Efficacy of FOLFIRI Plus Cetuximab or FOLFOX Plus Cetuximab as First-line Therapy in Subjects With KRAS Wild-type Metastatic Colorectal Cancer (APEC-Study)(APEC) | completed | Phase 1 / Phase 2 | 289 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 1 | May 14, 2015 | clinicaltrials |
| NCT01047475 | A Phase II Trial of MB-6 Plus FOLFOX4 for Metastatic Colorectal Cancer (FDA IND 103675) | completed | Phase 2 | 72 | Microbio Co LtdINDUSTRY | 1 | May 13, 2015 | clinicaltrials |
| NCT01443377 | Neoadjuvant Radiochemotherapy Combined With Panitumumab in Locally Advanced KRAS Wild-type Rectal Cancer(NEOREC-1) | completed | Phase 2 | 48 | National Center for Tumor Diseases, HeidelbergOTHER | 1 | May 7, 2015 | clinicaltrials |
| NCT01639326 | Study to Evaluate the Efficacy and Safety of FOLFIRI-AD in Patients With Metastatic Colorectal Cancer UGT1A Genotype 1(FOLFIRI-AD) | unknown | Phase 2 | 96 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauOTHER | 1 | May 7, 2015 | clinicaltrials |
| NCT01103479 | Low-Literacy Physician-Patient Intervention Promoting Colorectal Cancer Screening | completed | Phase 2 / Phase 3 | 569 | Northwestern UniversityOTHER | 1 | May 6, 2015 | clinicaltrials |
| NCT02235324 | Ziv-Aflibercept Followed by Ziv-Aflibercept, Fluorouracil, and Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer | withdrawn | Phase 2 | 0 | University of Southern CaliforniaOTHER | 1 | May 6, 2015 | clinicaltrials |
| NCT00459901 | Study of the Antitumor Activity of Capecitabine in Combination With Erlotinib in Patients With Metastatic Colorectal Cancer | terminated | Phase 2 | 13 | Peter KozuchOTHER | 1 | Apr 29, 2015 | clinicaltrials |
| NCT02423226 | Computed Tomography-guided Brachytherapy Plus Chemotherapy for Locally Recurrent Rectum Cancer | completed | Phase 2 | 56 | The First People's Hospital of ChangzhouOTHER | 0 | Apr 22, 2015 | clinicaltrials |
| NCT00230399 | Combination Chemotherapy Treatments in Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 15 | University of Michigan Rogel Cancer CenterOTHER | 1 | Apr 21, 2015 | clinicaltrials |
| NCT02419677 | Radiofrquency Ablation Combined With Cytokine-induced Killer Cells for Colorectal Cancer Liver Metastases | completed | Phase 2 / Phase 3 | 60 | The First People's Hospital of ChangzhouOTHER | 1 | Apr 17, 2015 | clinicaltrials |
| NCT00032110 | Erlotinib in Treating Patients With Recurrent or Metastatic Colorectal Cancer | completed | Phase 2 | 30 | National Cancer Institute (NCI)NIH | 1 | Apr 15, 2015 | clinicaltrials |
| NCT00077298 | Bevacizumab and Cetuximab With or Without Irinotecan in Treating Patients With Irinotecan-Refractory Metastatic Colorectal Cancer | completed | Phase 2 | 70 | National Cancer Institute (NCI)NIH | 1 | Apr 15, 2015 | clinicaltrials |
| NCT01916239 | Pomegranate Extract Supplementation in Colorectal Cancer Patients(POMEcolon) | completed | Phase 1 / Phase 2 | 60 | National Research Council, SpainOTHER_GOV | 1 | Apr 14, 2015 | clinicaltrials |
| NCT02415699 | DC-CIK Immunotherapy Plus Chemotherapy vs Chemotherapy Alone in the Adjuvant Treatment of Stage III Colorectal Cancer | unknown | Phase 2 / Phase 3 | 100 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 0 | Apr 14, 2015 | clinicaltrials |
| NCT02415829 | Efficacy and Safety of Oxaliplatin Combined With Capecitabine as Neoadjuvant Chemotherapy for Locally Advanced Colon Cancer Patients | unknown | Phase 2 | 55 | Fudan UniversityOTHER | 1 | Apr 14, 2015 | clinicaltrials |
| NCT01941953 | Metformin and 5-fluorouracil for Refractory Colorectal Cancer. | completed | Phase 2 | 50 | Instituto do Cancer do Estado de São PauloOTHER | 1 | Apr 8, 2015 | clinicaltrials |
| NCT01531777 | Dose Finding and Pharmacokinetics/Pharmacodynamics Study of Apatinib in the Treatment of Advanced Colorectal Cancer | completed | Phase 2 | 40 | Jiangsu HengRui Medicine Co., Ltd.INDUSTRY | 1 | Apr 3, 2015 | clinicaltrials |
| NCT01277406 | 4SC-201 (Resminostat) in Advanced Colorectal Carcinoma(SHORE) | completed | Phase 1 / Phase 2 | 17 | 4SC AGINDUSTRY | 1 | Apr 1, 2015 | clinicaltrials |
| NCT00551421 | Pertuzumab and Cetuximab in Treating Patients With Previously Treated Locally Advanced or Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 17 | National Cancer Institute (NCI)NIH | 1 | Mar 31, 2015 | clinicaltrials |
| NCT00958386 | Safety and Efficacy Study of Panitumumab+Irinotecan in Patients Wild-Type (WT) KRAS Metastatic Colorectal Cancer Refractory to Irinotecan Based Chemotherapy (SPECTRA)(SPECTRA) | completed | Phase 2 | 61 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)OTHER | 1 | Mar 24, 2015 | clinicaltrials |
| NCT01071655 | Selecting Treatment in Colorectal Cancer:Capecitabine or 5-fluorouracil Selection to be Combined With Oxaliplatin or Irinotecan as First-line Chemotherapy in Advanced Colorectal Cancer(SETICC) | completed | Phase 2 | 195 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)OTHER | 1 | Mar 24, 2015 | clinicaltrials |
| NCT01126112 | Study of First-line Single-agent Panitumumab in Frail Elderly Patients With Advanced Wild Type K-RAS Colorectal Cancer(FRAIL) | completed | Phase 2 | 33 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)OTHER | 1 | Mar 24, 2015 | clinicaltrials |
| NCT01215539 | Study of Panitumumab-Capecitabine-Oxaliplatin In Wild-Type K-Ras Metastatic Colorectal Cancer Patients | completed | Phase 2 | 78 | Hellenic Cooperative Oncology GroupOTHER | 1 | Mar 18, 2015 | clinicaltrials |
| NCT02075086 | Angiogenic Switch in Patients With Colorectal Cancer(ANGIOSWITCH) | unknown | Phase 2 | 100 | Grupo Hospital de MadridOTHER | 1 | Mar 17, 2015 | clinicaltrials |
| NCT02295930 | Induction Chemoterapy With Folfoxiri Plus Cetuxumab in Unresectable Colorectal Cancer Patient(MACBETH) | completed | Phase 2 | 143 | Gruppo Oncologico del Nord-OvestOTHER | 1 | Mar 12, 2015 | clinicaltrials |
| NCT01579357 | Pharmacokinetics and Metabolic Activation of Capecitabine | completed | Phase 2 | 24 | Arbeitsgemeinschaft medikamentoese TumortherapieOTHER | 1 | Mar 9, 2015 | clinicaltrials |
| NCT00575640 | Hydralazine as a Demethylating Agent in Rectal Cancer | withdrawn | Phase 1 / Phase 2 | 0 | University of ArkansasOTHER | 0 | Mar 4, 2015 | clinicaltrials |
| NCT02376452 | Phase II Study of 2-weekly RAILIRI Versus FOLFIRI as Second-line Treatment in Advanced Colorectal Cancer Patients | unknown | Phase 2 | 100 | Fudan UniversityOTHER | 1 | Mar 3, 2015 | clinicaltrials |
| NCT00103311 | SB-715992 in Treating Patients With Advanced or Metastatic Colorectal Cancer | completed | Phase 2 | 64 | National Cancer Institute (NCI)NIH | 1 | Mar 2, 2015 | clinicaltrials |
Data updated 24 days agoSource updated Jul 29, 2015source: clinicaltrials