Subtype
Malignant Colorectal Neoplasm
CI-CAN-00005874Explore in graph →
1,565 active trials21 approved drugs382 evidence items
- NCIt
- C4978
- DOID
- 9256
- Other
- 1 more code
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Subtype
CI-CAN-00005874Explore in graph →
Clinical trials
7,296 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (722)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03727763 | Cetuximab and Vemurafenib Plus FOLFIRI for BRAF V600E Mutated Advanced Colorectal Cancer (IMPROVEMENT) | unknown | Phase 2 | 30 | Shanghai Changzheng HospitalOTHER | 1 | Aug 19, 2021 | clinicaltrials |
| NCT04906733 | Cetuximab Sensitivity Correlation Between Patient-Derived Organoids and Clinical Response in Colon Cancer Patients. | unknown | — | 80 | D1 Medical Technology (Shanghai) Co., Ltd, ChinaINDUSTRY | 1 | Aug 13, 2021 |
| clinicaltrials |
| NCT04999072 | Carbohydrate Antigen 19-9 in Colorectal Cancer | unknown | — | 4,972 | Seoul National University HospitalOTHER | 1 | Aug 10, 2021 | clinicaltrials |
| NCT04267575 | Canady Helios Cold Plasma Scalpel Treatment at the Surgical Margin and Macroscopic Tumor Sites | unknown | N/A | 20 | Jerome Canady, M.D.OTHER | 1 | Aug 9, 2021 | clinicaltrials |
| NCT04989855 | Fruquintinib Plus PD-1 Antibody in pMMR / MSS Locally Advanced Rectal Cancer (LARC) With High Immune Score | unknown | Phase 2 | 48 | Sun Yat-sen UniversityOTHER | 1 | Aug 4, 2021 | clinicaltrials |
| NCT04988191 | Toripalimab Plus Bevacizumab and Chemotherapy as Neoadjuvant Therapy in Advanced MSI-H or dMMR Colorectal Cancer | unknown | Phase 1 / Phase 2 | 44 | Peking UniversityOTHER | 1 | Aug 3, 2021 | clinicaltrials |
| NCT04980950 | "The Impact of Immunonutrition on Gut Microbiota-related Aspects in Colorectal Cancer and Gastric Cancer Patients" | unknown | N/A | 80 | Medical University of GdanskOTHER | 0 | Jul 30, 2021 | clinicaltrials |
| NCT04970498 | Application of MRI in Identifying Myelosuppression Risk of Neoadjuvant Chemoradiotherapy for Rectal Cancer | unknown | — | 120 | Peking University Third HospitalOTHER | 1 | Jul 21, 2021 | clinicaltrials |
| NCT04969029 | Immunotherapy Versus Chemotherapy as Adjuvant Therapy for Colon Cancer With MSI-H or POLE/ POLD1 Mutations | unknown | Phase 2 | 30 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Jul 20, 2021 | clinicaltrials |
| NCT02533271 | Optimization of Preoperative Treatment in Locally Advanced Rectal Cancer(STELLAR) | unknown | Phase 3 | 600 | Chinese Academy of Medical SciencesOTHER | 1 | Jul 16, 2021 | clinicaltrials |
| NCT03958435 | Real-world Retrospective Data Analysis of Adjuvant Therapy for Patients With Stage II-III Colon Cancer After Radical Surgery | unknown | — | 20,000 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Jul 15, 2021 | clinicaltrials |
| NCT04131803 | Probiotics Combined With Standard Chemotherapy Plus Targeted Therapy in Patients With Metastatic Colorectal Cancer | unknown | N/A | 140 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 0 | Jul 15, 2021 | clinicaltrials |
| NCT04380012 | A Clinical Study of Pyrotinib in Patients With HER2-positive Advanced Colorectal Cancer | unknown | Phase 2 | 40 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Jul 15, 2021 | clinicaltrials |
| NCT02546596 | The Effect of Electro-Hyperthermia in Preoperative Radiotherapy for Locally Advanced Rectal Cancer | unknown | N/A | 76 | Yonsei Hyperthermia Study GroupOTHER | 1 | Jul 13, 2021 | clinicaltrials |
| NCT04947930 | Fecal Metagenomics and Metabolomics Analyses to Identify Potential Screening Biomarkers for Colorectal Polyps and Cancer in Chinese Population | unknown | — | 600 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Jul 1, 2021 | clinicaltrials |
| NCT04293419 | Durvalumab (MEDI4736) Plus Total Neoadjuvant Therapy (TNT) in Locally Advanced Rectal Cancer(DUREC) | unknown | Phase 2 | 58 | Grupo Espanol Multidisciplinario del Cancer DigestivoOTHER | 1 | Jun 21, 2021 | clinicaltrials |
| NCT04929652 | Surufatinib Combine With Immunotherapy and Chemotherapy for Second-line Treatment in Advanced Colorectal Cancer | unknown | Phase 1 / Phase 2 | 48 | Jiangsu Cancer Institute & HospitalOTHER | 1 | Jun 18, 2021 | clinicaltrials |
| NCT04687384 | Systemic and Peritoneal Inflammatory Response In Robotic-assisted And Laparoscopic Surgery for Colon Cancer | unknown | N/A | 50 | University of Southern DenmarkOTHER | 1 | Jun 16, 2021 | clinicaltrials |
| NCT04924686 | Changes of Muramyl Dipeptide in Intestinal and Extra-intestinal Diseases | unknown | — | 600 | Zhujiang HospitalOTHER | 1 | Jun 14, 2021 | clinicaltrials |
| NCT04664504 | A Prospective Phase II Study of Individualized Neoadjuvant Chemoradiotherapy for Rectal Cancer Based on Recurrence Risk | unknown | Phase 2 | 150 | Jing Jin, M.D.UNKNOWN | 1 | Jun 8, 2021 | clinicaltrials |
| NCT04917263 | IMMUNOlogical Microenvironment in REctal Adenocarcinoma Treatment.(IMMUNOREACT2) | unknown | — | 544 | University of PadovaOTHER | 1 | Jun 8, 2021 | clinicaltrials |
| NCT04917276 | Treatment Response Prediction System of mCRC Patients Based on CTC | unknown | — | 100 | Fudan UniversityOTHER | 0 | Jun 8, 2021 | clinicaltrials |
| NCT04917289 | CTC vs Radiography as the Evidence of Recurrence in Colorectal Cancer Patients | unknown | Phase 3 | 100 | Fudan UniversityOTHER | 0 | Jun 8, 2021 | clinicaltrials |
| NCT04913233 | Establishment and Clinical Validation of New Technologies for Accurate Screening of Colorectal Cancer Based on Multi-omics | unknown | — | 9,000 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Jun 4, 2021 | clinicaltrials |
| NCT04912258 | Preoperative Irinotecan Drug-eluting Beads for Patients With Unresectable Colorectal Liver Metastasis | unknown | Phase 3 | 80 | Fudan UniversityOTHER | 1 | Jun 3, 2021 | clinicaltrials |
| NCT04912882 | Prognosis Predicting of CRC Patients Based on Morphology and Molecular Biomaker of CTC | unknown | — | 1,000 | Fudan UniversityOTHER | 0 | Jun 3, 2021 | clinicaltrials |
| NCT04907864 | Effect of Multi-modal Intervention Care on Cachexia in Patients With Advanced Cancer Compared to Conventional Management (MIRACLE)(MIRACLE) | unknown | Phase 2 | 112 | Kil Yeon LeeOTHER | 1 | Jun 1, 2021 | clinicaltrials |
| NCT04535024 | The Combination of Immunotherapy and Stereotactic Ablative Radiotherapy in MSS Oligometastatic Colorectal Cancer | unknown | Phase 2 | 60 | Fudan UniversityOTHER | 1 | May 11, 2021 | clinicaltrials |
| NCT04879004 | EFFECT - EFFectiveness of ESPB (Erector Spinae Plane Block) in Laparoscopic Cοlectomies Trial(EFFECT) | unknown | N/A | 40 | Democritus University of ThraceOTHER | 1 | May 10, 2021 | clinicaltrials |
| NCT03256084 | Tumoral Circulating Cells and Colorectal Cancer Progression | unknown | N/A | 120 | Institut Paoli-CalmettesOTHER | 1 | May 6, 2021 | clinicaltrials |
| NCT04870879 | Colorectal Metastasis and Liver Transplantation With Organs From Deceased Donors(MELODIC) | unknown | N/A | 18 | Azienda Ospedaliera di PadovaOTHER | 1 | May 4, 2021 | clinicaltrials |
| NCT02942706 | Cetuximab Maintenance Treatment Versus Continuation After Induction Therapy in mCRC | unknown | Phase 2 / Phase 3 | 200 | Ruijin HospitalOTHER | 0 | Apr 30, 2021 | clinicaltrials |
| NCT04672603 | Complete Versus Partial Preservation of Denonvilliers' Fascia on Urogenital Function in Locally Advanced Rectal Cancer | unknown | N/A | 214 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Apr 29, 2021 | clinicaltrials |
| NCT04862793 | Computerized Feedback in Colonoscopy | unknown | N/A | 3,000 | Copenhagen Academy for Medical Education and SimulationOTHER | 0 | Apr 28, 2021 | clinicaltrials |
| NCT04863768 | Molecular Profiling of Colorectal Cancer | unknown | — | 300 | Hellenic Cooperative Oncology GroupOTHER | 1 | Apr 28, 2021 | clinicaltrials |
| NCT04495387 | Improving Food Pleasure and Intake of Oncology Patients Receiving Chemotherapy | unknown | — | 100 | University of FlorenceOTHER | 0 | Apr 27, 2021 | clinicaltrials |
| NCT04850027 | MRI-guided Lateral Lymph Node Dissection in Rectal Cancer | unknown | — | 268 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Apr 26, 2021 | clinicaltrials |
| NCT02167321 | Rectal Cancer, Adjuvant Chemotherapy, FOLFOX(5-fluorouracil/Leucovorin/Oxaliplatin), Total Mesorectal Excision | unknown | Phase 2 | 90 | Yonsei UniversityOTHER | 1 | Apr 22, 2021 | clinicaltrials |
| NCT03286738 | Pattern of Use of Bevacizumab or Cetuximab + FOLFIRI Regimen as First-line Treatment in Metastatic Colorectal Cancer | unknown | — | 1,800 | Joong Bae AhnOTHER | 1 | Apr 22, 2021 | clinicaltrials |
| NCT04852250 | Centralized Tumour Board and Secondary Intervention Rate in mCRC | unknown | — | 130 | Ludwig-Maximilians - University of MunichOTHER | 0 | Apr 21, 2021 | clinicaltrials |
| NCT04853784 | Prospective Registration Study of Totally Laparoscopy Versus Laparoscopy Assisted Colon Cancer Surgery(STARS-CC01) | unknown | — | 650 | The First Hospital of Jilin UniversityOTHER | 1 | Apr 21, 2021 | clinicaltrials |
| NCT04851054 | Postoperative VEGF and Recurrence After Colon Cancer Surgery | unknown | — | 280 | Hospital del MarOTHER | 0 | Apr 20, 2021 | clinicaltrials |
| NCT04848311 | Indocanine Green as Tracer for Lymph Nodes Dissection in Station 253 | unknown | N/A | 66 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Apr 19, 2021 | clinicaltrials |
| NCT04843189 | Prospective Registration Study of Robtic Laparoscopy Versus Laparoscopy Assisted Colon Cancer Surgery(STARS-CC02) | unknown | — | 648 | The First Hospital of Jilin UniversityOTHER | 1 | Apr 13, 2021 | clinicaltrials |
| NCT04838496 | Induction Chemotherapy for Locally Advanced Rectal Cancer(MEND-IT) | unknown | Phase 2 | 128 | Catharina Ziekenhuis EindhovenOTHER | 1 | Apr 9, 2021 | clinicaltrials |
| NCT04823793 | Fecal DNA Methylation Test for Colorectal Cancer Screening | unknown | — | 80 | Tri-Service General Hospital (TSGH)OTHER | 1 | Apr 8, 2021 | clinicaltrials |
| NCT04833036 | c-CetuIRI Versus Ersecond-line Irinotecan s-IRI-CetuIRI | unknown | Phase 2 | 120 | Fudan UniversityOTHER | 1 | Apr 6, 2021 | clinicaltrials |
| NCT04831528 | Decision-making of ctDNA in Patients With mCRC After Failure of First-line Treatment Containing Cetuximab - a Single-center, Phase II Clinical Study | unknown | — | 100 | Fudan UniversityOTHER | 0 | Apr 5, 2021 | clinicaltrials |
| NCT02752698 | Domestic Surgical Robot Clinical Study | unknown | N/A | 200 | The Third Xiangya Hospital of Central South UniversityOTHER | 1 | Apr 1, 2021 | clinicaltrials |
| NCT04819516 | Study of the Safety and Effectiveness of HIFU Combined With REGOTORI for Metastatic Colorectal Cancer | unknown | Phase 1 | 10 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Mar 29, 2021 | clinicaltrials |
Data updated 24 days agoSource updated Aug 19, 2021source: clinicaltrials