Clinical trial · Observational
Postoperative VEGF and Recurrence After Colon Cancer Surgery
Postoperative Serum VEGF Concentration as an Independent Prognostic Factor for Recurrence After Curative Colon Cancer Surgery. Multicentric Study.
NCT04851054CI-TRIAL-00051362unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this trial is to study the relationship between the angiogenic response to surgical aggression, determined through the serum levels of vascular endothelial growth factor (VEGF) on postoperative day four, and the tumor recurrence in patients with colon cancer operated with a curative intention.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Angiogenesis | — | UNRESOLVED | — |
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
| Recurrence | — | UNRESOLVED | — |
| Surgery | — | UNRESOLVED | — |
| VEGF Overexpression | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Surgery for colon cancer with intention to cure | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Patients after surgery for colon cancer with intention to cure
- description
- Patients with colon cancer admitted to the Colorectal Surgery Unit of the centers participating in the study, who will undergo elective surgical resection with potentially curative intention
- interventionNames
- Procedure: Surgery for colon cancer with intention to cure
Primary outcomes (1)
- measure
- VEGF in serum on postop day 4
- timeFrame
- Postoperative day 4
- description
- A 10cc sample of peripheral blood will be drawn on postoperative day 4
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with colon cancer admitted to the Colorectal Surgery Unit of the centers participating in the study, * Patients who will undergo elective surgical resection with potentially curative intention Exclusion Criteria: * Patients with metastatic disease * Patients with synchronous colon neoplasia or in the previous five years * Patients undergoing emergency surgery * Patients who do not sign the informed consent.
References
Publications (0)
Data not yet available
No reference posted for this study.