Clinical trial · Observational
Prognosis Predicting of CRC Patients Based on Morphology and Molecular Biomaker of CTC
Prognosis Predicting of CRC Patients Based on Morphology and Molecular Biomaker of Circulating Tumor Cells
NCT04912882CI-TRIAL-00052098unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Detecting circulating tumor cells from I-IV stage colorectal cancer patients pre-and post-operatively. Analyzing the morphology and biomarkers of CTCs and builting prognosis predicting model based on the morphology and biomarkers of CTCs. Verifying the prognosis model by the survival data.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Circulating Tumor Cell | — | UNRESOLVED | — |
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Circulating tumor cell | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Training Group
- description
- Training group including about 500 patients that be using to building the prognosis model
- interventionNames
- Diagnostic Test: Circulating tumor cell
- label
- Validation Group
- description
- Validation group including about another 500 patients that be using to validating the prognosis model
- interventionNames
- Diagnostic Test: Circulating tumor cell
Primary outcomes (2)
- measure
- Sensitivity
- timeFrame
- 1 year
- description
- The sensitivity of the predictive based on the number and type of circulating tumor cell
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Age 18-80 years; Histologically proven colorectal carcinoma (TNM stage I-IV) R0 resection is possible according to preoperative evaluation Written informed consent for participation in the trial. Exclusion Criteria: * Primary tumor or metastases not able to be removed radically Receiving any preoperative treatment (Including chemotherapy, radiotherapy and target therapy) Have other malignant tumors meanwhile Other previous malignancy within 5 years
References
Publications (0)
Data not yet available
No reference posted for this study.