Malignant Choroid Plexus Neoplasm — Variants & evidence

Malignant Choroid Plexus Neoplasm — Variants & evidence · CancerIndex

Variants & evidence

Curated clinical evidence by variant and therapy

2 evidence items mapped to this entity or its descendants, grouped by molecular profile, then therapy. 50 items per page.

civicCuratedShowing 1–2 of 2 evidence items (2 on this page mapped to a descendant entity) · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
FOXO3 Mutation2
(prognostic)	Choroid Plexus Carcinoma	Prognostic	A	Supports Poor Outcome	3	rejected	EID7223 From UniProt: A chromosomal aberration involving FOXO3 is found in secondary acute leukemias. PMID 26822237 · Parsons et al., 2016 · Open in CIViC	civic
(functional)	Choroid Plexus Carcinoma	Functional	D	Supports Loss Of Function	4	rejected	EID7222 Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. PMID 26822237 · Parsons et al., 2016 · Open in CIViC	civic

Data updated 16 hours agoSource updated unknownsource: civic (CC0)

Evidence levels, directions and ratings are those assigned by CIViC curators. "Submitted" items have not completed curation review. This is not treatment guidance.