Cancer
Malignant Central Nervous System Neoplasm
CI-CAN-00001115Explore in graph →
Top-level822 active trials5 approved drugs103 evidence items
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Cancer
CI-CAN-00001115Explore in graph →
Clinical trials
2,864 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (418)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03551249 | Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption | completed | N/A | 20 | InSightecINDUSTRY | 1 | Mar 20, 2026 | clinicaltrials |
| NCT05393258 | Temporally-modulated Pulsed Radiation Therapy (TMPRT) After Prior EBRT for Recurrent IDH-mutant Gliomas | completed | N/A | 13 | Washington University School of MedicineOTHER | 1 | Mar 17, 2026 | clinicaltrials |
| NCT07472387 |
| Impact of Androgen Signaling on the Composition of the Immune Microenvironment in Glioblastomas(Andro-iGlio) |
| not yet recruiting |
| N/A |
| 40 |
| Assistance Publique - Hôpitaux de ParisOTHER |
| 1 |
| Mar 16, 2026 |
| clinicaltrials |
| NCT07459101 | UNIty-Based MR-Linac Guided Adaptive RadioThErapy for High GraDe Glioma-4(UNITED-4) | recruiting | N/A | 60 | Sunnybrook Health Sciences CentreOTHER | 1 | Mar 9, 2026 | clinicaltrials |
| NCT04908709 | Spectroscopic MRI Guided Proton Therapy in Assessing Metabolic Change in Pediatric Patients With Brain Tumors | recruiting | N/A | 25 | Emory UniversityOTHER | 1 | Mar 4, 2026 | clinicaltrials |
| NCT04243005 | Supramarginal Resection in Glioblastoma | active not recruiting | N/A | 90 | St. Olavs HospitalOTHER | 6 | Mar 3, 2026 | clinicaltrials |
| NCT07447531 | T2 Star Magnetic Resonance Imaging and Biomarker Blood Testing to Predict the Change and Progress of Malignant Gliomas | recruiting | N/A | 15 | John M. BuattiOTHER | 1 | Mar 3, 2026 | clinicaltrials |
| NCT06719440 | Achieving a Better Outcome Through Limiting the Glioblastoma Clinical Target Volume(BELGICA) | recruiting | N/A | 347 | Cliniques universitaires Saint-Luc- Université Catholique de LouvainOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT07426848 | OT SMILE: Occupational Therapy Group Intervention for Primary Brain Tumour Patients(OTSMILE) | recruiting | N/A | 96 | Royal College of Surgeons, IrelandOTHER | 1 | Feb 23, 2026 | clinicaltrials |
| NCT04268979 | Electronic Social Network Assessment Program (eSNAP) + Caregiver Navigator | completed | N/A | 296 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Feb 20, 2026 | clinicaltrials |
| NCT03450850 | Study Of NOVOTTF-200A In Bevacizumab-Naive Subjects With Recurrent Grade III Malignant Astrocytoma | completed | N/A | 1 | Daniela A. BotaOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT04278118 | Hypofractionated Proton Therapy for Benign Intracranial Brain Tumors, the HiPPI Study(HiPPI) | recruiting | N/A | 70 | Emory UniversityOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT06222138 | Study of Biologic Tumor and Plasma Biomarkers of Response to TTFields in Patients Treated for Newly Diagnosed Glioblastoma(EXOFIELDS) | recruiting | N/A | 80 | Institut Claudius RegaudOTHER | 1 | Feb 13, 2026 | clinicaltrials |
| NCT07406230 | Methotrexate Early Toxicity Monitoring(METoxiM) | not yet recruiting | N/A | 50 | Assistance Publique Hopitaux De MarseilleOTHER | 1 | Feb 12, 2026 | clinicaltrials |
| NCT07398066 | DEXmedetomidine for Postoperative Analgesia and Delirium Prevention After NEUROsurgery (DEX-NEURO Trial)(DEX-NEURO) | not yet recruiting | N/A | 60 | University of MalayaOTHER | 0 | Feb 9, 2026 | clinicaltrials |
| NCT05139277 | Evaluation of the CONVIVO System | recruiting | N/A | 30 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | Feb 6, 2026 | clinicaltrials |
| NCT01535911 | Pilot Study of a Metabolic Nutritional Therapy for the Management of Primary Brain Tumors(Ketones) | active not recruiting | N/A | 16 | Michigan State UniversityOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT03048240 | INtraoperative photoDYnamic Therapy of GliOblastoma(INDYGO) | completed | N/A | 10 | University Hospital, LilleOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT07368283 | Limited Target Volume Radiotherapy After Glioblastoma Surgery | not yet recruiting | N/A | 79 | Jiangxi Provincial Cancer HospitalOTHER | 0 | Jan 30, 2026 | clinicaltrials |
| NCT06592092 | Clinical Study of QH104 Cell Injection for the Treatment of Meningeal Metastases of B7H3+ Solid Tumors | completed | N/A | 3 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Jan 29, 2026 | clinicaltrials |
| NCT03251027 | Intensity-Modulated Stereotactic Radiation Therapy in Treating Patients With Grade II-IV Glioma | active not recruiting | N/A | 100 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | Jan 27, 2026 | clinicaltrials |
| NCT03144167 | Study of Prognostic Biomarkers of Survival at 6 Months for Patients Treated With Bevacizumab Glioblastomas in First Relapse After Failure of Radiochemotherapy(SPECTROBEVA) | recruiting | N/A | 170 | Centre Hospitalier Universitaire, AmiensOTHER | 1 | Jan 16, 2026 | clinicaltrials |
| NCT07339085 | Advanced Magnetic Resonance Imaging for the Identification of Recurrent Brain Tumors and Radiation Necrosis | recruiting | N/A | 42 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Jan 15, 2026 | clinicaltrials |
| NCT04745156 | A Study Using Brain Stimulation and Behavioral Therapy to Increase Extent of Resection in Low-Grade Gliomas | not yet recruiting | N/A | 3 | Medical College of WisconsinOTHER | 0 | Jan 12, 2026 | clinicaltrials |
| NCT07313709 | Measuring the Feasibility and Effect of a Virtual Reality Cognitive Training Intervention for Brain Cancer Survivors. | not yet recruiting | N/A | 40 | University of CincinnatiOTHER | 1 | Jan 2, 2026 | clinicaltrials |
| NCT01266096 | PET Imaging of Patients With Melanoma and Malignant Brain Tumors Using an 124I-labeled cRGDY Silica Nanomolecular Particle Tracer: A Microdosing Study | active not recruiting | N/A | 10 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Dec 31, 2025 | clinicaltrials |
| NCT05735171 | Supramarginal Resection in Glioblastoma Guided by Artificial Intelligence(SupraGlio-AI) | completed | N/A | 20 | Hospital del Rio HortegaOTHER | 1 | Dec 24, 2025 | clinicaltrials |
| NCT06468176 | Efficacy of a Mixed Distancial Neuropsychological Rehabilitation Program in Patients With Grade 2 or 3 Diffuse Glioma(FREEDOME) | recruiting | N/A | 187 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Dec 19, 2025 | clinicaltrials |
| NCT04566185 | Evaluation of the Predictive Value of 18F-fluorodeoxyglucose Positron Emission Tomography and Brain Perfusion Computed Tomography for the Efficacy of Anti-angiogenic Therapy (Bevacizumab) in Recurrent Glioblastoma(EVA DOPA) | completed | N/A | 14 | Centre Hospitalier Universitaire de NīmesOTHER | 1 | Dec 18, 2025 | clinicaltrials |
| NCT05976490 | NeuroPathways Intervention for Brain Tumor Patients | recruiting | N/A | 50 | Massachusetts General HospitalOTHER | 1 | Dec 17, 2025 | clinicaltrials |
| NCT06898684 | Medulloblastoma Online Video-based Exercise Pilot Study(MOVE) | recruiting | N/A | 15 | Aron OnerupOTHER_GOV | 2 | Dec 16, 2025 | clinicaltrials |
| NCT06098248 | Evaluation of cCeLL-Ex Vivo Confocal Microscopy for Real-time Brain Tumor Diagnosis(cCeLLExvivo) | terminated | N/A | 285 | VPIX MedicalINDUSTRY | 2 | Dec 15, 2025 | clinicaltrials |
| NCT05669326 | Evaluation of the Contribution of NODDI Protocol Tractography in Brain Tumor Surgery(NODDI-TRACT) | withdrawn | N/A | 0 | GCS Ramsay Santé pour l'Enseignement et la RechercheOTHER | 1 | Dec 3, 2025 | clinicaltrials |
| NCT06964815 | Silibinin in Association With Concomitant Chemoradiotherapy and Maintenance Temozolomide in STAT3 Positive IDH Wild-type, Newly Diagnosed Glioblastoma Patients(STRONG) | recruiting | N/A | 110 | Istituto Oncologico Veneto IRCCSOTHER | 1 | Dec 2, 2025 | clinicaltrials |
| NCT06776406 | Head Stabilization in Whole Brain RT | withdrawn | N/A | 0 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Nov 25, 2025 | clinicaltrials |
| NCT06930846 | HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)(HOBSCOTCH-CA) | recruiting | N/A | 125 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | Nov 21, 2025 | clinicaltrials |
| NCT07211841 | Correlative Analysis Between Magnetic Resonance Spectroscopy (MRS) and Essential Clinicobiological Data in Glioblatoma Multiforme (GBM)(GLIOMIT) | not yet recruiting | N/A | 30 | Centre Hospitalier Universitaire, AmiensOTHER | 1 | Nov 19, 2025 | clinicaltrials |
| NCT06090903 | Magnetic Resonance Imaging for Improving Knowledge of Brain Tumor Biology in Patients With Resectable Glioblastoma | recruiting | N/A | 50 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Nov 10, 2025 | clinicaltrials |
| NCT02162732 | Molecular-Guided Therapy for Childhood Cancer | completed | N/A | 186 | Giselle ShollerOTHER | 2 | Nov 3, 2025 | clinicaltrials |
| NCT00870129 | Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors | recruiting | N/A | 135 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Oct 10, 2025 | clinicaltrials |
| NCT06180460 | CALM: Managing Distress in Malignant Brain Cancer | completed | N/A | 60 | Virginia Commonwealth UniversityOTHER | 1 | Oct 8, 2025 | clinicaltrials |
| NCT05858359 | Contextualized Neuropsychological Rehabilitation for CNS Cancer Survivors: The ImPACT Program(ImPACT) | completed | N/A | 27 | Aarhus University HospitalOTHER | 1 | Oct 3, 2025 | clinicaltrials |
| NCT07198464 | Relmacabtagene Autoleucel Combined With Autologous Hematopoietic Stem Cell Transplantation, Orelabrutinib, and Sintilimab for Primary Central Nervous System Lymphoma | not yet recruiting | N/A | 30 | Zhengzhou UniversityOTHER | 0 | Sep 30, 2025 | clinicaltrials |
| NCT04344652 | Photoscreening for Retinoblastoma | withdrawn | N/A | 0 | Phoenix Children's HospitalOTHER | 0 | Sep 26, 2025 | clinicaltrials |
| NCT03026998 | MRI Screening of Second Primary Cancer Occurring Within Radiation Fields After Treatment by External Beam Radiation Therapy for Hereditary Retinoblastoma (DepiSCARRH)(DepiSCARRH) | active not recruiting | N/A | 88 | Institut CurieOTHER | 1 | Sep 15, 2025 | clinicaltrials |
| NCT03958240 | Deciphering Mechanisms Underlying Cancer Immunogenicity(DECIDE) | recruiting | N/A | 1,100 | Institut Claudius RegaudOTHER | 1 | Sep 15, 2025 | clinicaltrials |
| NCT07144735 | Allogeneic γδT Cells in Glioblastoma(ABOUT) | recruiting | N/A | 18 | Peking University Third HospitalOTHER | 1 | Aug 27, 2025 | clinicaltrials |
| NCT06582849 | Enhanced Assistance During Radiotherapy for Unmet Essential Needs(EARN) | completed | N/A | 33 | Washington University School of MedicineOTHER | 1 | Aug 26, 2025 | clinicaltrials |
| NCT07121842 | Glioblastoma Imaging for the Detection of Tumor Progression Using APTw-CEST MRI(GLIMPCE) | recruiting | N/A | 120 | Erasmus Medical CenterOTHER | 1 | Aug 14, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Mar 20, 2026source: clinicaltrials