Cancer
Malignant Central Nervous System Neoplasm
CI-CAN-00001115Explore in graph →
Top-level822 active trials5 approved drugs103 evidence items
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Cancer
CI-CAN-00001115Explore in graph →
Clinical trials
2,864 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (419)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04223999 | Improving Tumor Treating Fields Treatment for Brain Cancer Patients With Skullremodeling Surgery (Neurosurgery)(OptimalTTF-2) | unknown | Phase 2 | 70 | Anders Rosendal KorshøjOTHER | 1 | Jun 6, 2023 | clinicaltrials |
| NCT03411408 | Accelerated Hypofractionated Intensity - Modulated Radiotherapy After Hyperbaric Oxygenation for Recurrent High Grade Glioma.(HBO-RT) | unknown | N/A | 24 | Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS |
| 1 |
| May 30, 2023 |
| clinicaltrials |
| NCT05764460 | Social Cognition and Language in Patients With Gliomas | unknown | — | 105 | University Medical Center GroningenOTHER | 0 | May 17, 2023 | clinicaltrials |
| NCT05816746 | Decitabine and Anti-PD-1 in R/R DLBCL | unknown | Phase 2 | 20 | Chinese PLA General HospitalOTHER | 1 | May 9, 2023 | clinicaltrials |
| NCT05850377 | 5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas | unknown | — | 90 | Sociedad de Lucha Contra el Cáncer del EcuadorOTHER | 1 | May 9, 2023 | clinicaltrials |
| NCT02137759 | MRSI to Predict Response to RT/TMZ ± Belinostat in GBM | unknown | Phase 2 | 29 | Emory UniversityOTHER | 1 | May 6, 2023 | clinicaltrials |
| NCT04700514 | Effect of Anesthetic Drugs on Neurocognitive Function in Children With Retinoblastoma Requiring Multiple Anesthetic Exposure - Preliminary Study | unknown | N/A | 60 | Seoul National University HospitalOTHER | 1 | Apr 24, 2023 | clinicaltrials |
| NCT04359745 | Improving Treatment of Glioblastoma: Distinguishing Progression From Pseudoprogression | unknown | — | 500 | Guy's and St Thomas' NHS Foundation TrustOTHER | 1 | Apr 21, 2023 | clinicaltrials |
| NCT05170087 | Radiomic Analysis for Predicting Treatment Response and Clinical Outcomes in Malignancies | unknown | — | 1,200 | Sunnybrook Health Sciences CentreOTHER | 1 | Apr 19, 2023 | clinicaltrials |
| NCT05363826 | Intracavitary Photodynamic Therapy as an Adjuvant to Resection of Glioblastoma or Gliosarcoma Using IV Photobac® | unknown | Phase 1 | 30 | Photolitec LLCINDUSTRY | 1 | Apr 13, 2023 | clinicaltrials |
| NCT05811793 | Efficacy and Safety of SCAI of Bevacizumab Combined With IC of Tislelizumab in the Treatment of Recurrent Glioblastoma. | unknown | N/A | 36 | Second Affiliated Hospital of Nanchang UniversityOTHER | 0 | Apr 13, 2023 | clinicaltrials |
| NCT05793021 | FKBP51s: a New Molecular Biomarker for Glioblastoma? Pre- and Post-operative Blood Levels Evaluation of FKBP51s Protein and Correlation With MRI Phenotype | unknown | N/A | 70 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 31, 2023 | clinicaltrials |
| NCT01672463 | Clinical Trial of IV OKN-007 in a Pilot Cohort of Human Recurrent Malignant Glioma Patients(OKN-007) | unknown | Phase 1 | 31 | Oblato, Inc.INDUSTRY | 1 | Mar 29, 2023 | clinicaltrials |
| NCT03561207 | 3D Prediction of Patient-Specific Response(3D-PREDICT) | unknown | — | 570 | KIYATECINDUSTRY | 1 | Mar 24, 2023 | clinicaltrials |
| NCT05772741 | Grafts of GSCs Into Brain Organoids for Testing Anti-invasion Drugs(2253) | unknown | N/A | 160 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 16, 2023 | clinicaltrials |
| NCT05737368 | Treatment of Recurrent Glioblastoma With Fractionated Radiotherapy Combined With Cadonilimab | unknown | Phase 1 | 11 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 0 | Feb 21, 2023 | clinicaltrials |
| NCT04642937 | Study of CD200 Activation Receptor Ligand (CD200AR-L) and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent Glioblastoma | unknown | Phase 1 | 24 | OX2 TherapeuticsINDUSTRY | 1 | Jan 27, 2023 | clinicaltrials |
| NCT05700955 | Neoadjuvant Chemoimmunotherapy in Recurrent Glioblastoma | unknown | Phase 1 | 30 | University of LouisvilleOTHER | 1 | Jan 26, 2023 | clinicaltrials |
| NCT05694416 | Etoposide Plus Cisplatin Compared With Temozolomide in Patients With Glioblastoma | unknown | Phase 2 | 60 | Zhongnan HospitalOTHER | 0 | Jan 23, 2023 | clinicaltrials |
| NCT04840069 | Radiotherapy Planning Using Fluciclovine PET in Patients With Newly Diagnosed Glioblastoma | unknown | Phase 2 | 100 | St. Joseph's Hospital and Medical Center, PhoenixOTHER | 1 | Jan 13, 2023 | clinicaltrials |
| NCT04717739 | TIGER PRO-Active - Daily Activity, Sleep and Neurocognitive Functioning Study | unknown | — | 500 | NovoCure Ltd.INDUSTRY | 1 | Jan 10, 2023 | clinicaltrials |
| NCT05540873 | A Clinical Study of IL13Rα2 Targeted CAR-T in Patients With Malignant Glioma (MAGIC-I) | unknown | Phase 1 | 18 | CellabMEDINDUSTRY | 1 | Jan 6, 2023 | clinicaltrials |
| NCT04077866 | B7-H3 CAR-T for Recurrent or Refractory Glioblastoma | unknown | Phase 1 / Phase 2 | 40 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Dec 28, 2022 | clinicaltrials |
| NCT04385173 | Pilot Study of B7-H3 CAR-T in Treating Patients With Recurrent and Refractory Glioblastoma | unknown | Phase 1 | 12 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Dec 28, 2022 | clinicaltrials |
| NCT05667402 | Clinical Study of TBF Regimen in Allo-HSCT in Patients With CNS Leukemia | unknown | N/A | 50 | First Affiliated Hospital Xi'an Jiaotong UniversityOTHER | 1 | Dec 28, 2022 | clinicaltrials |
| NCT05663125 | LITT Combined With Early Use of Temozolomide for Recurrent Glioblastomas | unknown | Phase 1 / Phase 2 | 10 | Beijing Tiantan HospitalOTHER | 1 | Dec 23, 2022 | clinicaltrials |
| NCT05656300 | Glioblastoma Imaging Using a Strong Iron-like Bloodpool Contrast Medium? | unknown | — | 15 | Radboud University Medical CenterOTHER | 0 | Dec 19, 2022 | clinicaltrials |
| NCT05624736 | Hierarchical Diagnosis for Adult Diffuse Glioma Based on Deep Learning | unknown | — | 500 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolOTHER | 1 | Nov 22, 2022 | clinicaltrials |
| NCT04481815 | Rituximab Plus Methotrexate With or Without Lenalidomide in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma | unknown | Phase 2 | 240 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Nov 8, 2022 | clinicaltrials |
| NCT05600491 | A Phase III Study of Postoperative Early Temozolomide Treatment Plus STUPP Regimen for Newly Diagnosed GBM Multiforme | unknown | Phase 3 | 78 | Sun Yat-sen UniversityOTHER | 1 | Oct 31, 2022 | clinicaltrials |
| NCT05135858 | Dose Dense Re-challenge of High Dose Methotrexate With Glucarpidase for Relapsed Primary Central Nervous System Lymphoma(METHOGLU) | unknown | Phase 1 | 18 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Oct 25, 2022 | clinicaltrials |
| NCT05589961 | Safety and Efficacy of TRPP Therapy in Glioblastoma Multiforme | unknown | Early Phase 1 | 10 | The Second Hospital of Hebei Medical UniversityOTHER | 1 | Oct 21, 2022 | clinicaltrials |
| NCT03750071 | VXM01 Plus Avelumab Combination Study in Progressive Glioblastoma | unknown | Phase 1 / Phase 2 | 30 | Vaximm GmbHINDUSTRY | 1 | Oct 20, 2022 | clinicaltrials |
| NCT04438044 | A Study to Evaluate ICP-022 in Patients With R/R PCNSL and SCNSL | unknown | Phase 2 | 61 | Beijing InnoCare Pharma Tech Co., Ltd.INDUSTRY | 1 | Oct 12, 2022 | clinicaltrials |
| NCT05095441 | A Clinical Study of Intratumoral MVR-C5252 (C5252) in Patients With Recurrent or Progressive Glioblastoma | unknown | Phase 1 | 51 | ImmVira Pharma Co. LtdINDUSTRY | 1 | Oct 12, 2022 | clinicaltrials |
| NCT05557240 | Neoantigens Phase I Trial in Newly Diagnosed Glioblastoma Patients | unknown | N/A | 10 | Shanghai 10th People's HospitalOTHER | 1 | Oct 12, 2022 | clinicaltrials |
| NCT05556382 | Glioblastoma Evaluation for Heterogeneity In RadioseNsitivity(GEHIRN) | unknown | — | 30 | Istituto Clinico HumanitasOTHER | 1 | Oct 6, 2022 | clinicaltrials |
| NCT05305885 | Intra-pemetrexed Alone or Combined With Concurrent Radiotherapy for Leptomeningeal Metastasis | unknown | N/A | 100 | The First Hospital of Jilin UniversityOTHER | 1 | Sep 30, 2022 | clinicaltrials |
| NCT05515133 | Correlation Between Psychological Stress and Disease Progression in Newly Diagnosed Glioblastoma Patients | unknown | — | 60 | Henan Provincial People's HospitalOTHER | 1 | Sep 27, 2022 | clinicaltrials |
| NCT05539339 | Personalized Trial in ctDNA-level-relapse Glioblastoma | unknown | N/A | 20 | Henan Provincial People's HospitalOTHER | 1 | Sep 27, 2022 | clinicaltrials |
| NCT05556486 | Mapping of Tumor Stem Cells in the Resection Marigin During Extirpation of Highly Malignant Gliomas Using GlioStem(CeNo2) | unknown | — | 40 | Karolinska University HospitalOTHER | 1 | Sep 27, 2022 | clinicaltrials |
| NCT05549284 | Orelabrutinib,Rituximab and Methotrexate in Newly-diagnosed Primary Central Nervous System Lymphoma(PCNSL)(RMO) | unknown | Phase 2 | 36 | Affiliated Hospital to Academy of Military Medical SciencesOTHER | 1 | Sep 22, 2022 | clinicaltrials |
| NCT05267158 | The Cohort for Patient-reported Outcomes, Imaging and Trial Inclusion in Metastatic BRAin Disease (COIMBRA)(COIMBRA) | unknown | — | 1,000 | UMC UtrechtOTHER | 1 | Sep 6, 2022 | clinicaltrials |
| NCT05512195 | Safety and Efficacy of a New Approach to Delineating Clinical Target Volume of Glioblastoma(GBM) | unknown | N/A | 70 | Zhongnan HospitalOTHER | 0 | Aug 23, 2022 | clinicaltrials |
| NCT03722342 | TTAC-0001 and Pembrolizumab Combination phase1b Trial in Recurrent Glioblastoma | unknown | Phase 1 | 9 | PharmAbcineINDUSTRY | 1 | Aug 17, 2022 | clinicaltrials |
| NCT02285959 | Super-Selective Intraarterial Intracranial Infusion of Bevacizumab (Avastin) for Glioblastoma Multiforme | unknown | Phase 1 | 30 | Global Neurosciences InstituteOTHER | 1 | Aug 10, 2022 | clinicaltrials |
| NCT05493228 | Dexmedetomidine Infusion on Intraoperative Propofol,Fentanyl Requirements in Spine Surgery for Pediatric Cancer Patients | unknown | Phase 3 | 38 | Children's Cancer Hospital Egypt 57357OTHER | 1 | Aug 9, 2022 | clinicaltrials |
| NCT05117814 | Zanubrutinib Monotherapy in Relapsed/Refractory Central Nervous System Lymphoma | unknown | N/A | 20 | Peking University People's HospitalOTHER | 1 | Aug 3, 2022 | clinicaltrials |
| NCT05447195 | Phase 2 Study of CAN008 in Subjects With GBM | unknown | Phase 2 | 117 | CANbridge Life Sciences Ltd.INDUSTRY | 1 | Jul 12, 2022 | clinicaltrials |
Data updated 22 days agoSource updated Jun 6, 2023source: clinicaltrials