Cancer Family
Malignant Breast Neoplasm
CI-CAN-00000227Explore in graph →
Top-level2,627 active trials43 approved drugs310 evidence items
- NCIt
- C9335
- ICD-10
- C50
- DOID
- 1612
- Other
- 2 more codes
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Cancer Family
CI-CAN-00000227Explore in graph →
Clinical trials
12,360 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (1,368)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06926920 | A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer | recruiting | Phase 1 / Phase 2 | 100 | Gilead SciencesINDUSTRY | 3 | Jan 30, 2026 | clinicaltrials |
| NCT04680715 | Per-Operative Radiotherapy by Papillon +TM in Localized Breast Cancer(RPOS+2) | recruiting | Phase 2 | 40 | Centre Antoine LacassagneOTHER | 1 | Jan 29, 2026 | clinicaltrials |
| NCT03804944 | Converting HR+ Breast Cancer Into an Individualized Vaccine(CBCV) | recruiting | Phase 2 | 100 | Weill Medical College of Cornell UniversityOTHER | 1 | Jan 28, 2026 | clinicaltrials |
| NCT06715826 | Target-specific immunoPET Imaging of Breast Cancer | recruiting | Phase 1 / Phase 2 | 200 | RenJi HospitalOTHER | 1 | Jan 27, 2026 | clinicaltrials |
| NCT07371208 | Multicenter, Phase II Clinical Study of Sacituzumab Tirumotecan (Sac-TMT) in Combination With KL-A167 for Neoadjuvant Treatment of Triple-Negative Breast Cancer(ST-A-TN) | recruiting | Phase 2 | 40 | Shanghai Jiao Tong University School of MedicineOTHER | 1 | Jan 27, 2026 | clinicaltrials |
| NCT05693766 | Gene Signatures to Guide HR+MBC Therapy in a Diverse Cohort(INSIGHT) | recruiting | Phase 2 | 64 | Sonya ReidOTHER | 1 | Jan 20, 2026 | clinicaltrials |
| NCT05933395 | Genetically-informed Therapy for ER+ Breast Cancer Post-CDK4/6 Inhibitor(GERTRUDE) | recruiting | Phase 2 | 135 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | Jan 20, 2026 | clinicaltrials |
| NCT06682195 | Neoadjuvant Chemotherapy Combined With Toripalimab for TNBC (NEOTORCH-BREAST02) | recruiting | Phase 2 | 35 | First Affiliated Hospital of Zhejiang UniversityOTHER | 1 | Jan 14, 2026 | clinicaltrials |
| NCT05490472 | JAB-2485 Activity in Adult Patients With Advanced Solid Tumors | recruiting | Phase 1 / Phase 2 | 102 | Jacobio Pharmaceuticals Co., Ltd.INDUSTRY | 2 | Jan 9, 2026 | clinicaltrials |
| NCT06967103 | QL1706 for the Neoadjuvant Treatment of HR+/HER2- Breast Cancer | recruiting | Phase 2 | 238 | Henan Cancer HospitalOTHER_GOV | 1 | Jan 8, 2026 | clinicaltrials |
| NCT07327021 | MRI-Guided Neoadjuvant Treatment De-Escalation in Stage II-III TNBC(NOGA) | recruiting | Phase 2 | 54 | Tel-Aviv Sourasky Medical CenterOTHER_GOV | 1 | Jan 8, 2026 | clinicaltrials |
| NCT07002177 | A Phase Ib/II Study to Evaluate Multiple Combination Therapies of FWD1802 in Patients With ER+/HER2- BC | recruiting | Phase 1 / Phase 2 | 196 | Forward Pharmaceuticals Co., Ltd.INDUSTRY | 1 | Jan 7, 2026 | clinicaltrials |
| NCT06690840 | Atezolizumab and Chemotherapy Treatment as T-cell Activators in Metastatic Triple Negative Breast Cancer Patients(AZALEA) | recruiting | Phase 2 | 45 | European Institute of OncologyOTHER | 1 | Jan 5, 2026 | clinicaltrials |
| NCT05728268 | Neoadjuvant Dose-dense Chemotherapy for HR+/HER2- Breast Cancer Patients With High Proliferation Index | recruiting | Phase 2 | 64 | Shantou Central HospitalOTHER | 1 | Jan 2, 2026 | clinicaltrials |
| NCT07314073 | [18F]FES PET/CT for the Detection of Distant Metastasis in Low-grade ER-positive Stage III Breast Cancer | recruiting | Phase 2 | 85 | Asan Medical CenterOTHER | 1 | Jan 2, 2026 | clinicaltrials |
| NCT07037199 | Efficacy and Safety of Trastuzumab Rezetecan Followed by CDK4/6 Inhibitors and Endocrine Therapy in HR+/HER2-Low/Ultra-Low Advanced Breast Cancer | recruiting | Phase 2 | 45 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityOTHER | 1 | Dec 31, 2025 | clinicaltrials |
| NCT06452394 | NEODOXy: Targeting Breast Cancer Stem Cells With Doxycycline | recruiting | Phase 2 | 50 | Swiss Cancer InstituteOTHER | 1 | Dec 30, 2025 | clinicaltrials |
| NCT06596018 | Assessing Combined SBRT in Breast Cancer Non-Responders to Neoadjuvant Chemotherapy | recruiting | Phase 1 / Phase 2 | 96 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Dec 30, 2025 | clinicaltrials |
| NCT07310758 | Contrast-enhanced Ultrasound for Sentinel Node Detection | recruiting | Phase 2 / Phase 3 | 91 | The Netherlands Cancer InstituteOTHER | 1 | Dec 30, 2025 | clinicaltrials |
| NCT04965766 | Patritumab Deruxtecan (U3-1402) in Unresectable Locally Advanced or Metastatic Breast Cancer(ICARUS BREAST) | recruiting | Phase 2 | 139 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 1 | Dec 23, 2025 | clinicaltrials |
| NCT06085742 | BRE-08 Phase II Study of CMC Regimen for Early Stage Breast Cancer(BRE-08) | recruiting | Phase 2 | 25 | University of Illinois at ChicagoOTHER | 1 | Dec 19, 2025 | clinicaltrials |
| NCT06498154 | Eliminating Breast Surgery for Breast Cancer Patients With Clinical Complete Response to Neoadjuvant Systemic Therapy | recruiting | Phase 2 | 200 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Dec 19, 2025 | clinicaltrials |
| NCT04563507 | Combined Immunotherapies in Metastatic ER+ Breast Cancer | recruiting | Phase 2 | 102 | Weill Medical College of Cornell UniversityOTHER | 1 | Dec 15, 2025 | clinicaltrials |
| NCT04965064 | Trial of Neratinib Plus Capecitabine in Subjects With HER2-Negative Metastatic Breast Cancer With Brain Metastases and Abnormally Active HER2 Signaling | recruiting | Phase 2 | 22 | University of RochesterOTHER | 1 | Dec 15, 2025 | clinicaltrials |
| NCT06107673 | Dalpiciclib Plus AI (Neoadjuvant Endocrine Therapy) Compared With Neoadjuvant Chemotherapy in Early Breast Cancer (EBC) | recruiting | Phase 2 | 144 | Hebei Medical University Fourth HospitalOTHER | 1 | Dec 11, 2025 | clinicaltrials |
| NCT06943521 | A Study of MT-4561 in Patients With Various Advanced Solid Tumors | recruiting | Phase 1 / Phase 2 | 27 | Tanabe Pharma America, Inc.INDUSTRY | 2 | Dec 11, 2025 | clinicaltrials |
| NCT06961955 | 5 vs. 9-day Course of Whole Breast Radiotherapy With Boost for Early-stage Breast Cancer(FAST NOVEMBER) | recruiting | Phase 2 | 144 | University of UtahOTHER | 1 | Dec 9, 2025 | clinicaltrials |
| NCT06910761 | Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer | recruiting | Phase 2 | 35 | City of Hope Medical CenterOTHER | 1 | Dec 8, 2025 | clinicaltrials |
| NCT06238921 | Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain Metastases | recruiting | Phase 1 / Phase 2 | 31 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Dec 5, 2025 | clinicaltrials |
| NCT06731894 | Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors | recruiting | Phase 2 | 120 | City of Hope Medical CenterOTHER | 1 | Dec 5, 2025 | clinicaltrials |
| NCT06817525 | Nab-P+Cb+PD1 Inhibitors as Neoadjuvant Therapy for Early TNBC | recruiting | Phase 2 | 64 | Henan Cancer HospitalOTHER_GOV | 1 | Dec 5, 2025 | clinicaltrials |
| NCT06409390 | Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer | recruiting | Phase 2 | 15 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT05076682 | Reverse Triple Negative Immune Resistant Breast Cancer(Renaissance) | recruiting | Phase 2 | 80 | Fudan UniversityOTHER | 1 | Dec 3, 2025 | clinicaltrials |
| NCT06735131 | The Optimal Radioimmunotherapy Combinations for Advanced TNBC | recruiting | Phase 2 | 60 | Sun Yat-sen UniversityOTHER | 1 | Dec 3, 2025 | clinicaltrials |
| NCT06189209 | Efficacy and Safety of Tenalisib in Patients With Metastatic Triple Negative Breast Cancer (TNBC) | recruiting | Phase 2 | 40 | Rhizen Pharmaceuticals SAINDUSTRY | 1 | Dec 2, 2025 | clinicaltrials |
| NCT07259226 | Optimal Methods to Characterize ADC Resistance in Solid Tumors and Identify Clinically Useful Biomarkers(OASIS) | recruiting | Phase 2 | 400 | UNICANCEROTHER | 1 | Dec 2, 2025 | clinicaltrials |
| NCT07159451 | A Short-term Preoperative, Evaluating Activity and Safety of Elacestrant Monotherapy as Compared to Elacestrant + Ovarian Function Suppression (LHRH Agonist) in Premenopausal Patients With Stage I-II ER+/HER2- Breast Cancer(POP-ELA) | recruiting | Phase 2 | 140 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 1 | Dec 1, 2025 | clinicaltrials |
| NCT05982678 | Basket Study for Oligo-metastatic Breast Cancer(ANISE) | recruiting | Phase 2 | 72 | The Netherlands Cancer InstituteOTHER | 1 | Nov 26, 2025 | clinicaltrials |
| NCT06107686 | A Study of YL202 in Selected Patients With Advanced Solid Tumors | recruiting | Phase 2 | 200 | MediLink Therapeutics (Suzhou) Co., Ltd.INDUSTRY | 1 | Nov 26, 2025 | clinicaltrials |
| NCT07245069 | Use of Dapagliflozin in Primary Prevention of Cardiotoxicity of Anthracycline Chemotherapy in Breast Cancer Patients(Alpaca) | recruiting | Phase 2 | 100 | University Medical Centre LjubljanaOTHER | 1 | Nov 24, 2025 | clinicaltrials |
| NCT06185205 | ASHBY: Accelerated Super-Hypofractionated Breast Brachytherapy(ASHBY) | recruiting | Phase 2 | 170 | Virginia Commonwealth UniversityOTHER | 1 | Nov 21, 2025 | clinicaltrials |
| NCT05530057 | Eribulin With or Without Trastuzumab-biosimilar in Patients With HER2-overexpressed Recurrent or Stage IV Breast Cancer(ESPERO) | recruiting | Phase 2 | 180 | Seoul National University HospitalOTHER | 1 | Nov 20, 2025 | clinicaltrials |
| NCT06535893 | Sustainable and Efficient Platform Trial of New Therapeutic Development for Early Breast Cancer | recruiting | Phase 2 | 100 | Nagoya City UniversityOTHER | 1 | Nov 20, 2025 | clinicaltrials |
| NCT07233499 | Evaluation of the Cardioprotective Effect of Nebivolol on Trastuzumab-Induced Cardiotoxicity in Breast Cancer Patients | recruiting | Phase 2 | 56 | Ain Shams UniversityOTHER | 1 | Nov 19, 2025 | clinicaltrials |
| NCT06364267 | Low Dose Exemestane vs Low Dose Tamoxifen in Post-menopausal Women at High Risk for Breast Cancer.(BabyTears) | recruiting | Phase 2 | 140 | Andrea DeCensiOTHER | 1 | Nov 18, 2025 | clinicaltrials |
| NCT07130383 | A Study of MHB036C Combined With MHB039A in Patients With Advanced Breast Cancer or Other Advanced Malignant Solid Tumors | recruiting | Phase 2 | 210 | Minghui Pharmaceutical (Hangzhou) LtdINDUSTRY | 1 | Nov 18, 2025 | clinicaltrials |
| NCT07180082 | Continuous or Intermittent Pyrotinib for HER2-positive Advanced Breast Cancer(CORIN-PYRA) | recruiting | Phase 2 | 186 | Wenjin YinOTHER | 1 | Nov 18, 2025 | clinicaltrials |
| NCT07180160 | Iparomlimab and Tuvonralimab (QL1706) in Patients With HR-positive, HER2-negative Advanced Breast Cancer(ITHRAN) | recruiting | Phase 2 | 123 | Wenjin YinOTHER | 1 | Nov 18, 2025 | clinicaltrials |
| NCT05973864 | Capecitabine Plus Pembrolizumab in Patients With Triple Negative Breast Cancer After Chemo-immunotherapy and Surgery(CAPPA) | recruiting | Phase 2 | 220 | UNICANCEROTHER | 1 | Nov 17, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Jan 30, 2026source: clinicaltrials