Cancer Family
Malignant Breast Neoplasm
CI-CAN-00000227Explore in graph →
Top-level2,627 active trials43 approved drugs310 evidence items
- NCIt
- C9335
- ICD-10
- C50
- DOID
- 1612
- Other
- 2 more codes
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Cancer Family
CI-CAN-00000227Explore in graph →
Clinical trials
12,360 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (1,368)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03071926 | Metronomic PLD in Patients With Primary Endocrine Resistant ABC | unknown | Phase 2 | 46 | Fudan UniversityOTHER | 1 | Apr 20, 2022 | clinicaltrials |
| NCT04192903 | Chidamide Combined With Cisplatin for Relapsed or Metastatic Triple-negative Breast Cancer | unknown | Phase 2 | 55 | Fudan UniversityOTHER | 1 | Apr 20, 2022 | clinicaltrials |
| NCT04609215 |
| ImmunoBreast - A Phase Ib Study |
| unknown |
| Phase 1 / Phase 2 |
| 20 |
| Henrik DitzelOTHER |
| 1 |
| Apr 20, 2022 |
| clinicaltrials |
| NCT04634747 | Phase 2 Study to Evaluate PVX-410 + Pembrolizumab + Chemotherapy for Metastatic, PD-L1+ Triple-Negative Breast Cancer | unknown | Phase 2 | 53 | OncoPep, Inc.INDUSTRY | 0 | Apr 20, 2022 | clinicaltrials |
| NCT04745975 | Guided Treatment Based on Mini-PDX in Metastatic Triple Negative Breast Cancer | unknown | Phase 2 | 100 | Fudan UniversityOTHER | 1 | Apr 20, 2022 | clinicaltrials |
| NCT05334810 | DP303c in Patients With HER2-positive Unresectable Locally Advanced, Relapsed, or Metastaticbreast Cancer | unknown | Phase 2 | 191 | CSPC ZhongQi Pharmaceutical Technology Co., Ltd.INDUSTRY | 0 | Apr 19, 2022 | clinicaltrials |
| NCT05331326 | A Study of RC48-ADC for the Treatment of HER2-expression Metastatic Breast Cancer With Abnormal Activation of PAM Pathway | unknown | Phase 2 | 64 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Apr 15, 2022 | clinicaltrials |
| NCT04004910 | A Study Comparing Immunopheresis® Alone or In Combination With Chemotherapy Versus Chemotherapy Alone in Treatment of Advanced Breast Cancer Patients | unknown | Phase 1 / Phase 2 | 170 | Immunicom IncINDUSTRY | 2 | Mar 24, 2022 | clinicaltrials |
| NCT02499367 | Nivolumab After Induction Treatment in Triple-negative Breast Cancer (TNBC) Patients(TONIC) | unknown | Phase 2 | 84 | The Netherlands Cancer InstituteOTHER | 1 | Mar 22, 2022 | clinicaltrials |
| NCT04669587 | ER+/HER2- Locally Advanced or Metastatic Breast Cancer (ENZENO Study)(ENZENO) | unknown | Phase 1 / Phase 2 | 106 | EnhancedBio USA Inc.OTHER | 2 | Mar 22, 2022 | clinicaltrials |
| NCT05288127 | Efficacy of Talazoparib in Asian Metastatic Breast Cancer Patients With a Homologous Recombinant Deficiency (HRD) Signature | unknown | Phase 2 | 55 | University of MalayaOTHER | 1 | Mar 21, 2022 | clinicaltrials |
| NCT04389073 | Safety and Efficacy of Toripalimab in HER2- Metastatic Breast Cancer Patients Treated With Metronomic Vinorelbine | unknown | Phase 2 | 138 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Feb 25, 2022 | clinicaltrials |
| NCT03145961 | A Trial Using ctDNA Blood Tests to Detect Cancer Cells After Standard Treatment to Trigger Additional Treatment in Early Stage Triple Negative Breast Cancer Patients(c-TRAK-TN) | unknown | Phase 2 | 208 | Institute of Cancer Research, United KingdomOTHER | 1 | Feb 24, 2022 | clinicaltrials |
| NCT05255523 | Pyrotinib Plus Trastuzumab After First-line TH (P) Treatment With HER-2 Positive Breast Cancer | unknown | Phase 2 | 60 | Fujian Medical University Union HospitalOTHER | 0 | Feb 24, 2022 | clinicaltrials |
| NCT02630368 | A Study of Metronomic CP and JX-594 in Patients With Advanced Breast Cancer and Advanced Soft-tissue Sarcoma (METROmaJX)(METROmaJX) | unknown | Phase 1 / Phase 2 | 197 | Institut BergoniéOTHER | 1 | Feb 2, 2022 | clinicaltrials |
| NCT05192278 | Comparison of Different Volumes Spread of Erector Spinae Block in Post Mastectomy Pain Syndrome Management | unknown | Phase 2 | 50 | Mansoura UniversityOTHER | 1 | Jan 14, 2022 | clinicaltrials |
| NCT05189067 | Efficacy and Safety of Adjuvant Docetaxel and Trastuzumab in Stage I HER2-positive Breast Cancer | unknown | Phase 2 / Phase 3 | 190 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Jan 12, 2022 | clinicaltrials |
| NCT05089643 | Anrotinib in Combination With Capecitabine in Advanced Triple Negative Breast Cancer | unknown | Phase 2 | 35 | Chinese Academy of Medical SciencesOTHER | 1 | Jan 10, 2022 | clinicaltrials |
| NCT02595320 | Capecitabine in Metastatic Breast and GI Cancers(X7-7) | unknown | Phase 2 | 200 | Qamar KhanOTHER | 1 | Dec 20, 2021 | clinicaltrials |
| NCT05154396 | Neratinib Dose Escalation Regimen for HER2 Positive Early Breast Cancer | unknown | Phase 2 | 60 | Chinese Academy of Medical SciencesOTHER | 0 | Dec 13, 2021 | clinicaltrials |
| NCT03238495 | Randomized Trial of Neo-adjuvant Chemotherapy With or Without Metformin for HER2 Positive Operable Breast Cancer(HERMET) | unknown | Phase 2 | 100 | Qamar KhanOTHER | 1 | Dec 7, 2021 | clinicaltrials |
| NCT01613560 | Clinical Study of Adjuvant Therapy on Post-menopausal Women With Breast Cancer Under the Guidance of the Results of Preoperative Endocrinotherapy | unknown | Phase 2 | 404 | Tao OUYANGOTHER | 1 | Nov 29, 2021 | clinicaltrials |
| NCT05134519 | RC48 for Neoadjuvant Chemotherapy of HER2 Positive Breast Cancer | unknown | Phase 2 | 20 | Xijing HospitalOTHER | 0 | Nov 26, 2021 | clinicaltrials |
| NCT01210768 | A Study of Pegylated Liposomal Doxorubicin and Cyclophosphamide in Her2-negative Stage I and II Breast Cancer Patients | unknown | Phase 2 | 254 | TTY BiopharmINDUSTRY | 1 | Nov 23, 2021 | clinicaltrials |
| NCT04781725 | INVINCIBLE TRIAL: Intratumoral INT230-6 in Breast Cancer | unknown | Phase 2 | 90 | Ottawa Hospital Research InstituteOTHER | 1 | Nov 17, 2021 | clinicaltrials |
| NCT05103917 | A Study to Assess the Safety, Tolerability and Antitumor Activity of X4P-001 in Combination With TNBC | unknown | Phase 1 / Phase 2 | 24 | Abbisko Therapeutics Co, LtdINDUSTRY | 1 | Nov 2, 2021 | clinicaltrials |
| NCT05097248 | Camrelizumab in Combination With PLD and Losartan in Patients With TNBC Who Have Received ≦ 1 Line of Chemotherapy | unknown | Phase 2 | 52 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Oct 28, 2021 | clinicaltrials |
| NCT05088057 | Neoadjuvant Camrelizumab Plus Chemotherapy in Triple Negative Breast Cancer | unknown | Phase 2 | 30 | Aiping ShiOTHER | 1 | Oct 21, 2021 | clinicaltrials |
| NCT05025735 | Alpelisib, Fulvestrant and Dapagliflozin for the Treatment of HR+, HER2 -, PIK3CA Mutant Metastatic Breast Cancer | unknown | Phase 2 | 25 | Saint Luke's Health SystemOTHER | 1 | Oct 19, 2021 | clinicaltrials |
| NCT05068141 | A Study to Evaluate the Efficacy and Safety of SG001 in Combination With Nab-Paclitaxel in Patients With Advanced Triple-Negative Breast Cancer (TNBC) | unknown | Phase 2 | 79 | CSPC ZhongQi Pharmaceutical Technology Co., Ltd.INDUSTRY | 1 | Oct 15, 2021 | clinicaltrials |
| NCT04407988 | Pyrotinib in Combination With Letrozole in Patients With HER2-Positive, ER-Positive Metastatic Breast Cancer | unknown | Phase 2 | 86 | Hunan Cancer HospitalOTHER | 1 | Oct 13, 2021 | clinicaltrials |
| NCT05076695 | Neoadjuvant With Trastuzumab, Pyrotinib Plus Palbociclib and Fulvestrant in HER2-positive, ER-positive Breast Cancer(NeoTPPF) | unknown | Phase 2 | 37 | Fudan UniversityOTHER | 1 | Oct 13, 2021 | clinicaltrials |
| NCT04061863 | Nivolumab and Eribulin in HER2 Negative Metastatic Breast Cancer(KORNELIA) | unknown | Phase 1 / Phase 2 | 90 | Seoul National University HospitalOTHER | 1 | Sep 8, 2021 | clinicaltrials |
| NCT05020964 | Screening Plasma HER2 Amplication by Digital PCR in Advanced Breast Cancer Patients Treated With Trastuzumab and Pyrotinib | unknown | Phase 2 | 68 | Chinese Academy of Medical SciencesOTHER | 0 | Aug 25, 2021 | clinicaltrials |
| NCT04996836 | Breast Cancer, Omics, and Precision Medicine(BR(E)2ASTOME) | unknown | Phase 2 | 200 | University of Campania Luigi VanvitelliOTHER | 0 | Aug 13, 2021 | clinicaltrials |
| NCT04999540 | Tucidinostat and Fulvestrant in Hormone-receptor Positive Advanced Breast Cancer | unknown | Phase 2 | 73 | Guangdong Women and Children HospitalOTHER | 0 | Aug 11, 2021 | clinicaltrials |
| NCT02917005 | PalbocIclib in PreMenopausal Women With ER Positive/HER-2 Negative MetAstatic Breast Cancer(FATIMA) | unknown | Phase 2 | 160 | Hamdy A. AzimOTHER | 1 | Jul 28, 2021 | clinicaltrials |
| NCT04975451 | ADCb (Anlotinib/Docetaxel/Carboplatin) as Neoadjuvant Therapy for Triple-Negative Breast Cancer | unknown | Phase 2 | 30 | Anqin ZhangOTHER | 1 | Jul 27, 2021 | clinicaltrials |
| NCT04452370 | Oral Etoposide Combined With Anlotinib in Advanced Triple Negative Breast Cancer | unknown | Phase 2 | 100 | Chinese Academy of Medical SciencesOTHER | 1 | Jul 21, 2021 | clinicaltrials |
| NCT03580395 | Apatinib in Neoadjuvant Therapy for Patients With Breast Cancer | unknown | Phase 2 / Phase 3 | 200 | Hebei Medical University Fourth HospitalOTHER | 1 | Jul 9, 2021 | clinicaltrials |
| NCT04941885 | Inetetamab Plus Cyclophosphamide Metronomic Chemotherapy Plus Aromatase Inhibitor in Metastatic HER2+/HR+ Breast Cancer(Increase) | unknown | Phase 2 | 78 | Sun Yat-sen UniversityOTHER | 1 | Jul 2, 2021 | clinicaltrials |
| NCT04946227 | Pembrolizumab and Paclitaxel in Hormone Receptor-positive, hyperMUTATted Metastatic Breast Cancer Identified by Whole exOme sequeNcing ('MUTATION2') | unknown | Phase 2 | 52 | Yonsei UniversityOTHER | 1 | Jun 30, 2021 | clinicaltrials |
| NCT04936295 | Fulvestrant Plus Anlotinib in HR(+)/HER2(-) Metastatic Breast Cancer With FGFR Mutation | unknown | Phase 2 | 61 | Sun Yat-sen UniversityOTHER | 1 | Jun 23, 2021 | clinicaltrials |
| NCT04922008 | Stage I HER2 Positive Invasive Breast Cancer De-escalation Study(IRIS-C/D) | unknown | Phase 2 | 356 | Fudan UniversityOTHER | 0 | Jun 10, 2021 | clinicaltrials |
| NCT04717531 | Pyrotinib as Neoadjuvant Agent for Non-objective Response HER2-positive Early Breast Cancer | unknown | Phase 2 | 60 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Jun 4, 2021 | clinicaltrials |
| NCT04913571 | Tislelizumab in Combination With Eribulin for Patients With Metastatic Previously heaviLy-treAted TriplE-negative Breast Cancer:A Prospective Multiple-center Phase II Study(TEMPLATE) | unknown | Phase 2 | 265 | Fudan UniversityOTHER | 1 | Jun 4, 2021 | clinicaltrials |
| NCT04024800 | Establishing the Recommended Biological Dose for AE37 Peptide Vaccine in Combination With Pembrolizumab That Will Enhance the Tumor-specific Immune Response and Demonstrate Efficacy in Patients With Advanced Triple-negative Breast Cancer(NSABP FB-14) | unknown | Phase 2 | 29 | NuGenerex Immuno-OncologyINDUSTRY | 1 | Jun 2, 2021 | clinicaltrials |
Data updated 23 days agoSource updated Apr 20, 2022source: clinicaltrials