Subtype
Malignant Biliary Tract Neoplasm
CI-CAN-00003139Explore in graph →
367 active trials6 approved drugs33 evidence items
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Subtype
CI-CAN-00003139Explore in graph →
Clinical trials
1,282 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (152)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04907643 | Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes | recruiting | N/A | 360 | Cedars-Sinai Medical CenterOTHER | 1 | Feb 20, 2026 | clinicaltrials |
| NCT06192719 | EULAT Eradicate GBC(EULAT) | recruiting | — | 15,000 | Centre Paul StraussOTHER | 5 | Feb 18, 2026 | clinicaltrials |
| NCT03445585 |
| Biobank for Cholestatic Liver Diseases. |
| recruiting |
| — |
| 9,150 |
| Mayo ClinicOTHER |
| 1 |
| Feb 17, 2026 |
| clinicaltrials |
| NCT04753996 | Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC Patients | recruiting | — | 300 | Mayo ClinicOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT05451290 | Camrelizumab Plus Apatinib in Combination With GEMOX (Gemcitabine and Oxaliplatin ) in Patients With Locally Advanced Biliary Tract Cancer | active not recruiting | Phase 2 | 30 | First Affiliated Hospital of Zhejiang UniversityOTHER | 1 | Feb 12, 2026 | clinicaltrials |
| NCT07326137 | A Prospective Observational Study of First-Line Systemic Therapy Combined With Celiac Plexus Blockade for Advanced Biliopancreatic Cancer With Pain | recruiting | — | 103 | Tongji HospitalOTHER | 1 | Feb 11, 2026 | clinicaltrials |
| NCT05430698 | PD-1 Antibody Plus GEMOX as Postoperative Adjuvant Therapy in Perihilar Cholangiocarcinoma | recruiting | Phase 2 | 62 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityOTHER | 1 | Feb 9, 2026 | clinicaltrials |
| NCT07223307 | REGULUS: MRI-guided Adaptive SABR for Liver Cancers | recruiting | Phase 2 | 62 | Stanford UniversityOTHER | 1 | Feb 9, 2026 | clinicaltrials |
| NCT07398339 | Cosiporfin Sodium for Injection Photodynamic Therapy(DVDMS) | recruiting | Phase 2 | 30 | Shanghai Guangsheng Biopharmaceutical Co., LtdINDUSTRY | 1 | Feb 9, 2026 | clinicaltrials |
| NCT04459273 | Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers(FAPI PET RDRC) | active not recruiting | Phase 1 | 26 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT07201519 | Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy | recruiting | Phase 2 | 80 | Michael J Cavnar, MDOTHER | 1 | Feb 4, 2026 | clinicaltrials |
| NCT06313203 | HAI-Floxuridine, or SIRT, Combined With Gemox For Patients With Intra-Hepatic Cholangiocarcinoma Not Amenable to Resection (TOMCAT)(TOMCAT) | recruiting | Phase 2 | 39 | Oslo University HospitalOTHER | 1 | Feb 2, 2026 | clinicaltrials |
| NCT07229625 | A Phase III Study of SHR-8068 in Combination With Adebrelimab and Platinum-Containing Chemotherapy Versus Durvalumab in Combination With Platinum-Containing Chemotherapy as First-line Treatment for Advanced Biliary Tract Cancer (BTC) | recruiting | Phase 3 | 604 | Suzhou Suncadia Biopharmaceuticals Co., Ltd.INDUSTRY | 1 | Jan 28, 2026 | clinicaltrials |
| NCT04005339 | NAPOLI-2: Fluorouracil, Leucovorin, and Nanoliposomal Irinotecan in Biliary Cancer | active not recruiting | Phase 2 | 48 | Georgetown UniversityOTHER | 1 | Jan 26, 2026 | clinicaltrials |
| NCT04781192 | The Purpose of This Trial is to Determine if Regorafenib Plus Durvalumab (MEDI4736) is Safe and Effective in Treatment of Chemo Refractory Advanced Biliary Tract Cancers | active not recruiting | Phase 1 / Phase 2 | 40 | University of Kansas Medical CenterOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT05210322 | Percutaneous Cholangiopancreatoscopy Registry | active not recruiting | — | 679 | Johns Hopkins UniversityOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT07364305 | HAIC Combined With Immune Therapy for Advanced, Non-Resectable ICC(Lalo) | recruiting | Phase 2 | 50 | Eastern Hepatobiliary Surgery HospitalOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT07359586 | Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia | recruiting | — | 1,200 | Zhejiang UniversityOTHER | 1 | Jan 22, 2026 | clinicaltrials |
| NCT06591520 | AK112 Combined With Chemotherapy Versus Durvalumab Combined With Chemotherapy in Advanced Biliary Tract Cancer | active not recruiting | Phase 3 | 682 | AkesoINDUSTRY | 1 | Jan 21, 2026 | clinicaltrials |
| NCT07328607 | Outcomes After Laparoscopic Versus Open Pancreaticoduodenectomy | recruiting | N/A | 90 | Minia UniversityOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT07351591 | A Phase II Trial of Organoid Drug Sensitivity Testing to Guide Therapy in Unresectable Biliary Tract Cancers | not yet recruiting | Phase 2 | 88 | Eastern Hepatobiliary Surgery HospitalOTHER | 0 | Jan 20, 2026 | clinicaltrials |
| NCT07353827 | FOLFOX-HAIC Combined With Donafenib and Pucotenlimab as First-Line Treatment for Unresectable Intrahepatic Cholangiocarcinoma | not yet recruiting | Phase 2 | 36 | Sun Yat-sen UniversityOTHER | 1 | Jan 20, 2026 | clinicaltrials |
| NCT07326189 | Preoperative Right Hepatic Artery Embolization for Locally Advanced Bismuth IIIb and IV Perihilar Cholangiocarcinoma(PHAE-PHCC) | not yet recruiting | N/A | 33 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityOTHER | 0 | Jan 16, 2026 | clinicaltrials |
| NCT07344116 | Hepatobiliary and Pancreatic Tumor Biobank | not yet recruiting | — | 300 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 0 | Jan 15, 2026 | clinicaltrials |
| NCT05668884 | GEMOX Combined With Donafenib and Tislelizumab in Advanced Biliary Tract Carcinoma | recruiting | Phase 2 | 93 | Fudan UniversityOTHER | 1 | Jan 14, 2026 | clinicaltrials |
| NCT07235007 | Repeated Endobiliary Radiofrequency Ablation Plus Durvalumab, Gemcitabine, and Cisplatin for Unresectable Extrahepatic Cholangiocarcinoma(BRAVE) | recruiting | N/A | 120 | Aichi Medical UniversityOTHER | 2 | Jan 13, 2026 | clinicaltrials |
| NCT07337850 | Prospective Evaluation of 68Ga-FAPI PET in Biliary Cancers(FAPi-2) | recruiting | — | 60 | Tata Memorial CentreOTHER | 1 | Jan 13, 2026 | clinicaltrials |
| NCT07328919 | Efficacy and Safety of TT-00420 (Tinengotinib) Tablets Versus Chemotherapy in Patients With Advanced Intrahepatic Cholangiocarcinoma Harboring FGFR2 Fusions/Rearrangements or Mutations | not yet recruiting | Phase 3 | 138 | TransThera Sciences (Nanjing), Inc.INDUSTRY | 1 | Jan 9, 2026 | clinicaltrials |
| NCT04353375 | HMPL-453 Tartrate in Advanced Intrahepatic Cholangiocarcinoma | recruiting | Phase 2 / Phase 3 | 235 | HutchmedINDUSTRY | 1 | Dec 31, 2025 | clinicaltrials |
| NCT06715839 | Target-specific immunoPET Imaging of Digestive System Carcinoma | recruiting | N/A | 400 | RenJi HospitalOTHER | 1 | Dec 31, 2025 | clinicaltrials |
| NCT07311798 | Impact of Vascular Resection on Survival and Postoperative Outcomes in Patients With Hilar Cholangiocarcinoma: A Retrospective Study | not yet recruiting | — | 300 | Yongjun ChenOTHER | 0 | Dec 31, 2025 | clinicaltrials |
| NCT07296666 | Adjuvant Chemotherapy for BTC Based on 3D-PTA | not yet recruiting | Phase 2 | 98 | Fudan UniversityOTHER | 0 | Dec 22, 2025 | clinicaltrials |
| NCT07291063 | Anti-PD-1/PD-L1 Antibodies Plus Gemcitabine and Cisplatin for Advanced CCA | recruiting | — | 50 | Shanghai Zhongshan HospitalOTHER | 1 | Dec 18, 2025 | clinicaltrials |
| NCT07291947 | PULSAR Combined With Immunotherapy and Chemotherapy | recruiting | Phase 1 / Phase 2 | 60 | Wang XinOTHER | 1 | Dec 18, 2025 | clinicaltrials |
| NCT06416397 | Diagnostic Approach for Cholangiocarcinoma Using Liquid Bile Biopsy(PROTEOBILE) | recruiting | — | 200 | University Hospital, BordeauxOTHER | 1 | Dec 16, 2025 | clinicaltrials |
| NCT04684862 | Infusion System for Hepatic Cancer | active not recruiting | N/A | 100 | Ronald DeMatteo, M.D.OTHER | 1 | Dec 15, 2025 | clinicaltrials |
| NCT07282262 | An Exploratory Study on the Use of Ivosidenib for the Precise Treatment of Advanced Biliary Tract Malignancies With IDH1 Mutations in the Later Line of Therapy. | recruiting | Phase 2 | 300 | Peking Union Medical College HospitalOTHER | 1 | Dec 15, 2025 | clinicaltrials |
| NCT06909188 | The Study of Association of Helicobacter Infections in Biliary Tract Cancers | recruiting | — | 250 | Institute of Liver and Biliary Sciences, IndiaOTHER | 1 | Dec 12, 2025 | clinicaltrials |
| NCT06943521 | A Study of MT-4561 in Patients With Various Advanced Solid Tumors | recruiting | Phase 1 / Phase 2 | 27 | Tanabe Pharma America, Inc.INDUSTRY | 2 | Dec 11, 2025 | clinicaltrials |
| NCT06546969 | Chemoimmunotherapy Combined With Hyperthermia and Spatially-Fractionated Radiotherapy in Advanced Biliary Tract Cancer | recruiting | Phase 1 | 15 | University of Maryland, BaltimoreOTHER | 1 | Dec 10, 2025 | clinicaltrials |
| NCT04238637 | Immunotherapy Combined With Y-90 SIRT Therapy in Advanced Stage Intrahepatic Biliary Tract Cancer (BTC) | active not recruiting | Phase 2 | 50 | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus NordwestOTHER | 1 | Dec 5, 2025 | clinicaltrials |
| NCT05174650 | Treatment of Atezolizumab and Derazantinib in Patients With Advanced iCCA With FGFR2 Fusions/Rearrangements | active not recruiting | Phase 2 | 27 | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus NordwestOTHER | 1 | Dec 5, 2025 | clinicaltrials |
| NCT07267078 | Tuvonralimab and Iparomlimab Based Regimens for the Neoadjuvant Treatment of Biliary Tract Cancer | recruiting | Phase 2 | 45 | Peking Union Medical College HospitalOTHER | 1 | Dec 5, 2025 | clinicaltrials |
| NCT05921552 | Senior Adult Hepatobiliary Prehab Study | active not recruiting | N/A | 25 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT07263217 | Mechanistic Study on the Protective and Regenerative Effects of Spirulina in Hepatectomy-Related Liver Injury | recruiting | N/A | 30 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT06440993 | Durvalumab + Intraductal Radiofrequency Ablation (ID-RFA) in Extrahepatic Cholangiocarcinoma | recruiting | Phase 2 | 42 | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus NordwestOTHER | 1 | Dec 1, 2025 | clinicaltrials |
| NCT07106827 | A Study of GV20-0251 in Advanced or Refractory Solid Tumors | recruiting | Phase 1 | 10 | West China HospitalOTHER | 1 | Nov 24, 2025 | clinicaltrials |
| NCT07237464 | To Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of GB18 Injection in Healthy Participants | recruiting | Phase 1 | 36 | Shenzhen Kexing Pharmaceutical Co., Ltd.NETWORK | 1 | Nov 19, 2025 | clinicaltrials |
| NCT03452774 | SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry | recruiting | — | 50,000 | Massive Bio, Inc.INDUSTRY | 2 | Oct 28, 2025 | clinicaltrials |
| NCT07208526 | A Randomized Trial of Surgical Decision-Making Guided by TDTP-RECIST | not yet recruiting | N/A | 270 | Shanghai Zhongshan HospitalOTHER | 1 | Oct 6, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Feb 20, 2026source: clinicaltrials