Clinical trial · Observational
Impact of Vascular Resection on Survival and Postoperative Outcomes in Patients With Hilar Cholangiocarcinoma: A Retrospective Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Hilar cholangiocarcinoma is a highly aggressive malignancy, and surgical resection remains the only potentially curative treatment. Due to the frequent involvement of major vascular structures, vascular resection is increasingly performed to achieve negative surgical margins; however, its impact on survival and postoperative outcomes remains controversial. This retrospective study aims to evaluate the association between vascular resection and clinical outcomes, including survival and postoperative outcomes, in patients with hilar cholangiocarcinoma undergoing curative-intent surgery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cholangiocarcinoma, Hilar | Hilar Cholangiocarcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| No Intervention: Observational Cohort | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Vascular Resection Group
- description
- Patients with hilar cholangiocarcinoma who underwent curative-intent surgery with concomitant vascular resection, including portal vein and/or hepatic artery resection.
- interventionNames
- Other: No Intervention: Observational Cohort
- label
- Non-Vascular Resection Group
- description
- Patients with hilar cholangiocarcinoma who underwent curative-intent surgery without vascular resection.
- interventionNames
- Other: No Intervention: Observational Cohort
Primary outcomes (2)
- measure
- Postoperative Complications Grade II or Higher (Clavien-Dindo ≥ II)
- timeFrame
- Within 30 days after surgery
- description
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Patients who underwent surgical treatment at the Department of Hepatobiliary and Pancreatic Surgery of our hospital between January 2010 and December 2024, including those with or without concomitant vascular resection. * Pathologically confirmed diagnosis of hilar cholangiocarcinoma after surgery. * Complete clinical and follow-up data available for outcome analysis. Exclusion Criteria: * Patients with distant metastasis or who underwent only palliative or exploratory surgery. * Patients diagnosed preoperatively or intraoperatively with other types of biliary malignancies not located at the hilar region. * Patients with incomplete medical records or missing key clinical or follow-up data.
References
Publications (0)
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