Subtype
Malignant Anorectal Neoplasm
CI-CAN-00005864Explore in graph →
452 active trials1 approved drugs6 evidence items
- NCIt
- C215225
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Subtype
CI-CAN-00005864Explore in graph →
Clinical trials
1,783 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (174)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00645710 | Hepatic Arterial Infusion of Floxuridine, Gemcitabine Hydrochloride, and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer Previously Treated With Surgery | completed | Phase 1 / Phase 2 | 16 | City of Hope Medical CenterOTHER | 1 | Mar 28, 2019 | clinicaltrials |
| NCT00321685 | Bevacizumab, Radiation Therapy, and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Locally Advanced Nonmetastatic Rectal Cancer | completed | Phase 2 | 57 | National Cancer Institute (NCI)NIH |
| 1 |
| Mar 27, 2019 |
| clinicaltrials |
| NCT00409994 | Safety Study of Rapamycin Administered Before and During Radiotherapy to Treat Rectum Cancer | completed | Phase 1 / Phase 2 | 44 | Maastricht Radiation OncologyOTHER | 1 | Mar 18, 2019 | clinicaltrials |
| NCT00423293 | Intensity-Modulated Radiation Therapy, Fluorouracil, and Mitomycin C in Treating Patients With Invasive Anal Cancer | completed | Phase 2 | 63 | Radiation Therapy Oncology GroupNETWORK | 2 | Feb 27, 2019 | clinicaltrials |
| NCT01585727 | Intraoperative Monitoring of the Pelvic Autonomic Nerves(NEUROS) | completed | N/A | 188 | Johannes Gutenberg University MainzOTHER | 1 | Feb 27, 2019 | clinicaltrials |
| NCT03202992 | Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection | completed | Phase 1 | 57 | Antiva BiosciencesINDUSTRY | 2 | Feb 7, 2019 | clinicaltrials |
| NCT03238885 | Predicting Pathological Complete Response of Rectal Cancer With Magnetic Resonance(MR) Radiomics | completed | — | 538 | Sun Ying-ShiOTHER | 1 | Feb 4, 2019 | clinicaltrials |
| NCT03506529 | Identification of Predictive Factors for Physiological Hypermetabolism of the Anal Canal in 18F-FDG PET / CT(HYPHYCA) | completed | — | 644 | Centre Francois BaclesseOTHER | 1 | Jan 11, 2019 | clinicaltrials |
| NCT01923337 | Irinotecan and Alisertib in Treating Patients With Advanced Solid Tumors or Colorectal Cancer | completed | Phase 1 | 17 | University of California, DavisOTHER | 1 | Jan 4, 2019 | clinicaltrials |
| NCT01282502 | Midostaurin (PKC412) for Locally Advanced Rectal Cancer | completed | Phase 1 | 19 | Massachusetts General HospitalOTHER | 1 | Dec 12, 2018 | clinicaltrials |
| NCT01560377 | Perfusion Assessment in Laparoscopic Left Anterior Resection(PILLAR II) | completed | Phase 1 | 147 | Novadaq Technologies ULC, now a part of StrykerINDUSTRY | 1 | Dec 11, 2018 | clinicaltrials |
| NCT03765411 | Safe Colorectal Surgery in the Elderly | completed | — | 6,740 | Tripler Army Medical CenterFED | 1 | Dec 5, 2018 | clinicaltrials |
| NCT00068692 | Comparison of Adjuvant Chemotherapy Regimens in Treating Stage II/III Rectal Cancer | completed | Phase 3 | 225 | National Cancer Institute (NCI)NIH | 1 | Dec 4, 2018 | clinicaltrials |
| NCT01651949 | Multivalent HPV (Human Papillomavirus) Vaccine Study in 16- to 26-Year Old Men and Women (V503-003) | completed | Phase 3 | 2,520 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Nov 27, 2018 | clinicaltrials |
| NCT00257322 | Cellular Immune Augmentation in Colon and Rectal Cancer | completed | Phase 2 | 20 | University of California, IrvineOTHER | 1 | Oct 31, 2018 | clinicaltrials |
| NCT02966509 | Engagement of Patients With Advanced Cancer(EPAC) | completed | N/A | 213 | Stanford UniversityOTHER | 0 | Oct 31, 2018 | clinicaltrials |
| NCT00094809 | Chemotherapy Administered Every 2 Weeks With or Without Pegfilgrastim in Subjects With Advanced or Metastatic Colon Cancer | completed | Phase 2 | 252 | AmgenINDUSTRY | 0 | Oct 17, 2018 | clinicaltrials |
| NCT00418938 | SPIRITT - Second-Line Panitumumab Irinotecan Treatment Trial | completed | Phase 2 | 266 | AmgenINDUSTRY | 0 | Oct 17, 2018 | clinicaltrials |
| NCT01460641 | Perfusion CT as a Predictor of Treatment Response in Patients With Rectal Cancer | completed | — | 21 | Stanford UniversityOTHER | 1 | Sep 7, 2018 | clinicaltrials |
| NCT02017509 | Immunoscore in Rectal Cancer | completed | — | 3 | Providence Health & ServicesOTHER | 1 | Aug 29, 2018 | clinicaltrials |
| NCT01590147 | Supportive Intervention Programs Study(SIPS) | completed | N/A | 15 | Wake Forest UniversityOTHER | 1 | Aug 15, 2018 | clinicaltrials |
| NCT02551471 | Benchmarking Trial Between France and Australia Comparing Management of Primary Rectal Cancer Beyond TME (Total Mesorectum Excision) and Locally Recurrent Rectal Cancer(PELVICARE) | completed | — | 165 | University Hospital, BordeauxOTHER | 2 | Aug 9, 2018 | clinicaltrials |
| NCT02127645 | Neoadjuvant Radiotherapy Followed by Transanal Endoscopic Microsurgery for T1-T2 Extraperitoneal Rectal Cancer(NERATEM) | completed | Phase 3 | 25 | European Association for Endoscopic SurgeryOTHER | 1 | Jul 26, 2018 | clinicaltrials |
| NCT02129218 | Low Glycemic Load Diet in Patients With Stage I-III Colon Cancer | completed | N/A | 18 | Case Comprehensive Cancer CenterOTHER | 1 | Jul 20, 2018 | clinicaltrials |
| NCT03589131 | Robotic-assisted Versus Conventional Laparoscopic Approach for Rectal Cancer Surgery | completed | N/A | 57 | National Cancer Institute, EgyptOTHER | 0 | Jul 17, 2018 | clinicaltrials |
| NCT01656044 | Negative Pressure Therapy in Preventing Infection After Surgery in Patients With Colon, Rectal, Pancreatic, or Peritoneal Surface Cancer | completed | N/A | 375 | Wake Forest University Health SciencesOTHER | 1 | Jul 3, 2018 | clinicaltrials |
| NCT02145416 | ART: Anal Squamous Cell Carcinoma: Investigation of Functional Imaging During chemoRadioTherapy(ART) | completed | — | 29 | University of OxfordOTHER | 1 | Jun 6, 2018 | clinicaltrials |
| NCT01528683 | Phase I/II Trial Evaluating Carbon Ion Radiotherapy for the Treatment of Recurrent Rectal Cancer(PANDORA) | completed | N/A | 14 | University Hospital HeidelbergOTHER | 1 | May 17, 2018 | clinicaltrials |
| NCT01285778 | Vectibix for the Treatment of Anal Cancer(VITAL) | completed | Phase 2 | 58 | Grupo Espanol Multidisciplinario del Cancer DigestivoOTHER | 1 | May 16, 2018 | clinicaltrials |
| NCT01182116 | Quality of Life in Patients That Undergo J Pouch or Side to End Coloanal Anastomosis for Rectal Cancer | completed | N/A | 46 | The Cleveland ClinicOTHER | 1 | May 9, 2018 | clinicaltrials |
| NCT00379743 | Partnership for Healthy Seniors | completed | N/A | 2,593 | Johns Hopkins Bloomberg School of Public HealthOTHER | 1 | Apr 26, 2018 | clinicaltrials |
| NCT02966054 | Self-monitoring and Reminder Texts to Increase Physical Activity After Cancer: a Pilot Randomized Controlled Trial(Smart Pace) | completed | N/A | 42 | University of California, San FranciscoOTHER | 1 | Apr 9, 2018 | clinicaltrials |
| NCT03469596 | Evaluation by MRI of Anal Canal Cell Carcinoma: is There Predictive Factor? | completed | — | 87 | Fondation Hôpital Saint-JosephOTHER | 1 | Mar 22, 2018 | clinicaltrials |
| NCT03085992 | Folfoxiri Plus Bevacizumab Followed by Chemoradiotherapy Plus Bevacizumab in Patients With Resectable Rectal Cancer(TRUST) | completed | Phase 2 | 49 | Azienda Ospedaliero, Universitaria PisanaOTHER | 1 | Mar 14, 2018 | clinicaltrials |
| NCT03465501 | Interstitial Brachytherapy Boost for Treatment of Anal Canal Cancers, Comparison of Two Dose Rates(BOOST-CA) | completed | — | 89 | Institut Paoli-CalmettesOTHER | 1 | Mar 14, 2018 | clinicaltrials |
| NCT01585428 | Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Human Papillomavirus-Associated Cancers | completed | Phase 2 | 29 | National Cancer Institute (NCI)NIH | 1 | Mar 7, 2018 | clinicaltrials |
| NCT02353858 | Preoperative Radiochemotherapy With Hyperthermia for Locally Advanced Rectal Cancer(HT01) | completed | Phase 2 | 78 | University Hospital TuebingenOTHER | 1 | Feb 13, 2018 | clinicaltrials |
| NCT01589471 | The Value of Botox-A for Management of Low Anterior Resection Syndrome | completed | Phase 2 | 23 | Centre hospitalier de l'Université de Montréal (CHUM)OTHER | 1 | Feb 12, 2018 | clinicaltrials |
| NCT03420443 | Action of Synbiotics on Irradiated GI Mucosa in Rectal Cancer Treatment(FIPIREX) | completed | N/A | 30 | Region SkaneOTHER | 0 | Feb 5, 2018 | clinicaltrials |
| NCT02041481 | MEK Inhibitor MEK162 in Combination With Leucovorin Calcium, Fluorouracil, and Oxaliplatin in Treating Patients With Advanced Metastatic Colorectal Cancer | completed | Phase 1 | 26 | City of Hope Medical CenterOTHER | 1 | Jan 25, 2018 | clinicaltrials |
| NCT00911170 | PAVES: Pegfilgrastim Anti-vascular Endothelial Growth Factor (VEGF) Evaluation Study | completed | Phase 3 | 847 | AmgenINDUSTRY | 17 | Dec 29, 2017 | clinicaltrials |
| NCT01589419 | A Clinical Study Conducted in Multiple Centers Evaluating Escalating Doses of Veliparib in Combination With Capecitabine and Radiation in Patients With Locally Advanced Rectal Cancer | completed | Phase 1 | 32 | AbbVie (prior sponsor, Abbott)INDUSTRY | 2 | Nov 20, 2017 | clinicaltrials |
| NCT02243267 | GI SPORE Colon Biosample Protocol | completed | — | 115 | University of MichiganOTHER | 1 | Nov 8, 2017 | clinicaltrials |
| NCT00972881 | Capecitabine, Irinotecan Hydrochloride, Cetuximab, and Radiation Therapy in Treating Patients Undergoing Surgery for Locally Advanced Rectal Cancer(EXCITE) | completed | Phase 1 / Phase 2 | 82 | University College, LondonOTHER | 1 | Oct 25, 2017 | clinicaltrials |
| NCT00682786 | Genotype-directed Neoadjuvant Chemoradiation for Rectal Carcinoma | completed | Phase 2 | 135 | Washington University School of MedicineOTHER | 1 | Oct 6, 2017 | clinicaltrials |
| NCT01340755 | Laparoscopy-Assisted Transanal Endoscopy Rectosigmoid Resection for Rectal Cancer | completed | N/A | 5 | Massachusetts General HospitalOTHER | 1 | Sep 6, 2017 | clinicaltrials |
| NCT02280811 | T Cell Receptor Immunotherapy Targeting HPV-16 E6 for HPV-Associated Cancers | completed | Phase 1 / Phase 2 | 12 | National Cancer Institute (NCI)NIH | 1 | Sep 6, 2017 | clinicaltrials |
| NCT00847119 | Xeloda and Bevacizumab to Treat Rectal Cancer(xeberecto) | completed | Phase 2 | 43 | Institut Català d'OncologiaOTHER | 1 | Aug 29, 2017 | clinicaltrials |
| NCT01333709 | Multicenter Phase 2 Trial: a Tailored Strategy for Locally Advanced Rectal Carcinoma(GRECCAR4) | completed | Phase 2 | 150 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Aug 21, 2017 | clinicaltrials |
Data updated 23 days agoSource updated Mar 28, 2019source: clinicaltrials